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Entry version 105 (12 Aug 2020)
Sequence version 1 (01 May 2000)
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Protein
Submitted name:

Sel1 repeat-containing protein, putative

Gene

PF3D7_0204100

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PLASMO:PFB0190C-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Sel1 repeat-containing protein, putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PF3D7_0204100Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaSarAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
PlasmoDB:PF3D7_0204100

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501906681922 – 2295Sequence analysisAdd BLAST2274

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9TY98

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9TY98, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9TY98

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni65 – 107DisorderedSequence analysisAdd BLAST43
Regioni120 – 154DisorderedSequence analysisAdd BLAST35
Regioni513 – 580DisorderedSequence analysisAdd BLAST68
Regioni1183 – 1212DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili714 – 734Sequence analysisAdd BLAST21
Coiled coili1628 – 1659Sequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi65 – 86PolyampholyteSequence analysisAdd BLAST22
Compositional biasi87 – 106PolarSequence analysisAdd BLAST20
Compositional biasi120 – 144PolyampholyteSequence analysisAdd BLAST25
Compositional biasi516 – 537PolarSequence analysisAdd BLAST22
Compositional biasi547 – 563AcidicSequence analysisAdd BLAST17
Compositional biasi564 – 580PolyampholyteSequence analysisAdd BLAST17

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_230208_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
QHSNEQH

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006597, Sel1-like
IPR011990, TPR-like_helical_dom_sf
IPR011004, Trimer_LpxA-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08238, Sel1, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00671, SEL1, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51161, SSF51161, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9TY98-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIKNVFYLNF IFSFFLLIIK CDESVSNGRK EIYFDDDEKL KLSSFFDRST
60 70 80 90 100
NINLDVGEND ELSSYVPREV DEKKKKNKKD IDSKENSKSG NNIYNKDNTK
110 120 130 140 150
NNEDVNYNVV LKDGRAKEGI ITDEKRRSST KDGKNKEQNN NKMNSDDVHD
160 170 180 190 200
NNNNMNDINF VVEYNKMIDN YDKILDELIL KSINRNNYNY FNMLDEYSLQ
210 220 230 240 250
TKLNKEMYDS LNYLIRLMNN KNSRKYFISF SNNEKKKIIK NDMNENIYIR
260 270 280 290 300
HFIVSLFRWY NNFKLIETCF DKNNFIYYID ENKIYSYKYN YKLMLNLFSS
310 320 330 340 350
ENFLYYINLS KFSLLEIIDN YNKYSFIINN IKRDYPNNMY VCQSFYDFIY
360 370 380 390 400
SYFLSYNHHF FDKHKYLINM DIWNNSIQTK GQIGNHKLYK KLKKLNENLI
410 420 430 440 450
LYNYIKNDDS EMIPYVTLEM RMIFSNFTNL LIDILNKLYN IDYQDNIKQE
460 470 480 490 500
NVNVNPQRDA PQDYVHNKND VDVSLKNVKE PKKVEHNKAM SNYETDERGD
510 520 530 540 550
MIYDNTNKEK FEKSEGTFNN ISGGEDTFKN ISGGEDTFKN ISEGDGEVDG
560 570 580 590 600
DGEGDGDGDG EGADDSSVDT HNNKNDGKES ESDVWNLLMD SYKKLANDEN
610 620 630 640 650
FKKYNKYILK NLDKFLNMSS EKKEDINSYK NKYELKEGII YNKVSDKYIP
660 670 680 690 700
LIFNPTKDVF TSINQINIKS KINFFNIYEY LITITKYKEN KNFYDDLLKC
710 720 730 740 750
RREIFFKDRH LLENNNIMDK QEELKKNIRN LMRIHEVSNE GNNRNTINRK
760 770 780 790 800
YKKYGTYDYD KMNELYYVEK NILNVNDTNT FNFMNNKEKD KNYFDINKTM
810 820 830 840 850
RIYDYYNNIN LNIFTPAAIK MKDKIYDQLK LLRSNFVEKL KNESICVLSF
860 870 880 890 900
LYLIGINDDN GKLHFPYGFP RNIDFSVKLI REGKDGLCNF LSGVLYHINL
910 920 930 940 950
PIFVNNSSIS ISTEMNDDVL EMNDNSINSF FYIYYKNNEN IRNHDFLSDE
960 970 980 990 1000
NRIIPRKEDN IKSKIISYSL GSSKDDFFSK LAFTNNVIRL KYKNKTNNTY
1010 1020 1030 1040 1050
LKDYFDFTFD KINYKNSVIK NNVSPFLTTC DYLLSNILGA VVDSLRNSST
1060 1070 1080 1090 1100
LESGVYEENI NDKNKNIIQN TVVQNKNLFE YFVKLADNRN SYALAALGEI
1110 1120 1130 1140 1150
YYLGNESIGI ERDEIKAFEF WKKAADQGDT TSALSTGYAY LDEYKKFLKK
1160 1170 1180 1190 1200
EELVKNMDRE DILTMIHLEN STKDKKNVTL EMFQESSEKK NQKKKKKEKK
1210 1220 1230 1240 1250
EQDGNTDGDR VDDKIVQNVG NVFQQSYGNV DESMGRNGSI DGFSMPPSGG
1260 1270 1280 1290 1300
LNNVSVQNNA NIQNNANIQN NANIQSNANI QNNANIQSNA NIQSNANIQS
1310 1320 1330 1340 1350
NANIQSNVNS HGGTNRQNNI NNVNFFENNA YTQQTSYGGW ANPSEDVFNN
1360 1370 1380 1390 1400
SFSSSVPSSF LFDIPEGSEY EHMTENILDE QMNFFNTKNN KEQQEGGPNN
1410 1420 1430 1440 1450
ESNGMWNDEN DEMIKKYMKD LNDDLNKSLK NAEEYFHKAI RNNDDSLENI
1460 1470 1480 1490 1500
LAKYNIHKFG LGTEKNIELA GIYLKKAADK GDNISQMLLG HYYSGSDIGI
1510 1520 1530 1540 1550
KLNDYKDDDK IENLRKSYKY YKMSAQNGNI ISLYNKSILI LKGVNPKYKT
1560 1570 1580 1590 1600
FNEKCEKTLK HFHFIGLFNE RLYMLTKLLR RNYQFKDYTG SLLLSIMLSE
1610 1620 1630 1640 1650
LGDHAHNVNA SMLWTLKRKT MQQFTEKYNI VENLKLSLIK ELKNKEEKEK
1660 1670 1680 1690 1700
EKRKNNIHNV YNNNNSNING YKKCDKNCND NVRKNQKDLN QIDHTIVKGD
1710 1720 1730 1740 1750
TPYYYEKNIN EKIKRIYKKN KNASYSFSKV RKMYSISLLT NCSMLSEFLR
1760 1770 1780 1790 1800
ERPLFSKIIY CYNFKRELYI YYNRLSWFTY QMMKMQHEDD LSDDKDRSEG
1810 1820 1830 1840 1850
WNSINIKKFN ENVQRDHVNR KENVNVKANA NVKANANVKE NANVKENANV
1860 1870 1880 1890 1900
KANANVKANA NVKANANVKE NANVKENANV KENANVKANA NVNDNANSVL
1910 1920 1930 1940 1950
NKNHNNDIYD YSYYKKNDER RNDKKSEFFN TSKNKKEEKK EIKITYHDTY
1960 1970 1980 1990 2000
DLCKKYSQIE LYEKYDKIIL NTLKKDDDVE EKINKIENMK SVILEHLRIS
2010 2020 2030 2040 2050
EFLHCYYKPI SYYQIKLEEE KEKRAKIDEH IYNEERYYKN DKSNYNSFYS
2060 2070 2080 2090 2100
NKWKTMKDYN IKNLYESEFY RYSVFLENID MKEIFNYKKK YSSNIFDEIQ
2110 2120 2130 2140 2150
SFSKNCEVCK QYYDIYSAYY GHKKSGINLI KKYREGDEFT IKSKRKELQF
2160 2170 2180 2190 2200
LIRNSDEDNH QSLYYKALFL EHNNLDNLKN ILQIYFKLAT DDHNTCNVIG
2210 2220 2230 2240 2250
FLGIMKIFFK KLFFDFNIFS KNNKKNIFTF PLKHKTFYDD NLCSLQKNIL
2260 2270 2280 2290
LKSEFDNKCF NFDYLLKNNY IYSQIRYSDF FKVLYNLILS FFKII
Length:2,295
Mass (Da):271,490
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i725403DF6586A060
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LN999943 Genomic DNA Translation: CZT98053.1

NCBI Reference Sequences

More...
RefSeqi
XP_001349553.1, XM_001349517.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CZT98053; CZT98053; PF3D7_0204100

GeneDB pathogen genome database from Sanger Institute

More...
GeneDBi
PF3D7_0204100.1:pep

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
812635

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pfa:PF3D7_0204100

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999943 Genomic DNA Translation: CZT98053.1
RefSeqiXP_001349553.1, XM_001349517.1

3D structure databases

SMRiQ9TY98
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9TY98, 1 interactor

Proteomic databases

PRIDEiQ9TY98

Genome annotation databases

EnsemblProtistsiCZT98053; CZT98053; PF3D7_0204100
GeneDBiPF3D7_0204100.1:pep
GeneIDi812635
KEGGipfa:PF3D7_0204100

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0204100

Phylogenomic databases

HOGENOMiCLU_230208_0_0_1
OMAiQHSNEQH

Enzyme and pathway databases

BioCyciPLASMO:PFB0190C-MONOMER

Family and domain databases

Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR006597, Sel1-like
IPR011990, TPR-like_helical_dom_sf
IPR011004, Trimer_LpxA-like_sf
PfamiView protein in Pfam
PF08238, Sel1, 3 hits
SMARTiView protein in SMART
SM00671, SEL1, 3 hits
SUPFAMiSSF51161, SSF51161, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9TY98_PLAF7
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9TY98
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: August 12, 2020
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
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