UniProtKB - Q9TW65 (DMD_CAEEL)
Dystrophin-1
dys-1
Functioni
Plays a role in cholinergic transmission and as a functional partner of dystrobrevin (dyb-1), necessary for muscle maintenance. Required for neuronal positioning.
5 PublicationsSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 3306 | Zinc 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 3309 | Zinc 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 3321 | Zinc 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 3324 | Zinc 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 3330 | Zinc 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 3333 | Zinc 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 3343 | Zinc 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 3347 | Zinc 2PROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 3301 – 3357 | ZZ-typePROSITE-ProRule annotationAdd BLAST | 57 |
GO - Molecular functioni
- actin binding Source: UniProtKB-KW
- zinc ion binding Source: InterPro
GO - Biological processi
- acetylcholine transport Source: UniProtKB
- forward locomotion Source: WormBase
- locomotory behavior Source: WormBase
- muscle cell cellular homeostasis Source: UniProtKB
- positive regulation of locomotion Source: UniProtKB
- positive regulation of synaptic transmission, cholinergic Source: WormBase
- sarcomere organization Source: WormBase
- synaptic signaling Source: GO_Central
- synaptic transmission, cholinergic Source: UniProtKB
Keywordsi
Molecular function | Actin-binding |
Ligand | Calcium, Metal-binding, Zinc |
Protein family/group databases
TCDBi | 8.A.66.1.1, the dystrophin (dystrophin) family |
Names & Taxonomyi
Protein namesi | Recommended name: Dystrophin-1 |
Gene namesi | Name:dys-1 ORF Names:F15D3.1 |
Organismi | Caenorhabditis elegans |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | F15D3.1a ; CE27129 ; WBGene00001131 ; dys-1 F15D3.1b ; CE24904 ; WBGene00001131 ; dys-1 |
Subcellular locationi
Cytoskeleton
Plasma membrane
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Plasma Membrane
- dystrobrevin complex Source: WormBase
- dystrophin-associated glycoprotein complex Source: UniProtKB
- plasma membrane Source: GO_Central
- sarcolemma Source: UniProtKB-SubCell
Other locations
- striated muscle dense body Source: WormBase
- synapse Source: GOC
Keywords - Cellular componenti
Cell membrane, Cytoplasm, Cytoskeleton, MembranePathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000076079 | 1 – 3674 | Dystrophin-1Add BLAST | 3674 |
Proteomic databases
EPDi | Q9TW65 |
PaxDbi | Q9TW65 |
PeptideAtlasi | Q9TW65 |
PRIDEi | Q9TW65 |
PTM databases
iPTMneti | Q9TW65 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | WBGene00001131, Expressed in multi-cellular organism and 5 other tissues |
ExpressionAtlasi | Q9TW65, baseline and differential |
Interactioni
Subunit structurei
Component of the dystrophin glycoprotein complex (DGC).
Interacts with dyb-1 and stn-1 to form the DGC.
Interacts with stn-2.
2 PublicationsBinary interactionsi
Q9TW65
With | #Exp. | IntAct |
---|---|---|
dyb-1 [Q9Y048] | 4 | EBI-446952,EBI-322698 |
GO - Molecular functioni
- actin binding Source: UniProtKB-KW
Protein-protein interaction databases
BioGRIDi | 38445, 6 interactors |
IntActi | Q9TW65, 3 interactors |
STRINGi | 6239.F15D3.1a |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 129 – 234 | Calponin-homology (CH)PROSITE-ProRule annotationAdd BLAST | 106 | |
Repeati | 327 – 435 | Spectrin 1Add BLAST | 109 | |
Repeati | 436 – 541 | Spectrin 2Add BLAST | 106 | |
Repeati | 612 – 656 | Spectrin 3Add BLAST | 45 | |
Repeati | 2576 – 2673 | Spectrin 4Add BLAST | 98 | |
Repeati | 2725 – 2789 | Spectrin 5Add BLAST | 65 | |
Repeati | 2792 – 2905 | Spectrin 6Add BLAST | 114 | |
Repeati | 2926 – 3032 | Spectrin 7Add BLAST | 107 | |
Domaini | 3047 – 3081 | WWPROSITE-ProRule annotationAdd BLAST | 35 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 25 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 30 – 39 | Actin-binding | 10 | |
Regioni | 265 – 325 | DisorderedSequence analysisAdd BLAST | 61 | |
Regioni | 655 – 689 | DisorderedSequence analysisAdd BLAST | 35 | |
Regioni | 968 – 991 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 1587 – 1606 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 1796 – 1833 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 2387 – 2466 | DisorderedSequence analysisAdd BLAST | 80 | |
Regioni | 3481 – 3522 | DisorderedSequence analysisAdd BLAST | 42 | |
Regioni | 3568 – 3645 | DisorderedSequence analysisAdd BLAST | 78 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 9 – 25 | Basic and acidic residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 265 – 283 | Polar residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 291 – 305 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 662 – 684 | Polar residuesSequence analysisAdd BLAST | 23 | |
Compositional biasi | 976 – 991 | Basic and acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 1796 – 1827 | Basic and acidic residuesSequence analysisAdd BLAST | 32 | |
Compositional biasi | 2388 – 2427 | Polar residuesSequence analysisAdd BLAST | 40 | |
Compositional biasi | 2430 – 2448 | Basic and acidic residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 2449 – 2466 | Polar residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 3481 – 3501 | Basic and acidic residuesSequence analysisAdd BLAST | 21 | |
Compositional biasi | 3502 – 3522 | Polar residuesSequence analysisAdd BLAST | 21 | |
Compositional biasi | 3568 – 3606 | Polar residuesSequence analysisAdd BLAST | 39 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 3301 – 3357 | ZZ-typePROSITE-ProRule annotationAdd BLAST | 57 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG4286, Eukaryota |
HOGENOMi | CLU_000246_3_0_1 |
InParanoidi | Q9TW65 |
OMAi | NQRWDAI |
OrthoDBi | 629209at2759 |
PhylomeDBi | Q9TW65 |
Family and domain databases
CDDi | cd00014, CH, 1 hit cd00201, WW, 1 hit |
Gene3Di | 1.10.418.10, 1 hit 3.30.60.90, 1 hit |
InterProi | View protein in InterPro IPR001589, Actinin_actin-bd_CS IPR001715, CH-domain IPR036872, CH_dom_sf IPR011992, EF-hand-dom_pair IPR015153, EF-hand_dom_typ1 IPR015154, EF-hand_dom_typ2 IPR018159, Spectrin/alpha-actinin IPR002017, Spectrin_repeat IPR001202, WW_dom IPR036020, WW_dom_sf IPR013087, Znf_C2H2_type IPR000433, Znf_ZZ IPR043145, Znf_ZZ_sf |
Pfami | View protein in Pfam PF00307, CH, 1 hit PF09068, EF-hand_2, 1 hit PF09069, EF-hand_3, 1 hit PF00435, Spectrin, 2 hits PF00569, ZZ, 1 hit |
SMARTi | View protein in SMART SM00033, CH, 1 hit SM00150, SPEC, 7 hits SM00456, WW, 1 hit SM00291, ZnF_ZZ, 1 hit |
SUPFAMi | SSF47473, SSF47473, 2 hits SSF47576, SSF47576, 1 hit SSF51045, SSF51045, 1 hit |
PROSITEi | View protein in PROSITE PS00019, ACTININ_1, 1 hit PS50021, CH, 1 hit PS01159, WW_DOMAIN_1, 1 hit PS50020, WW_DOMAIN_2, 1 hit PS50135, ZF_ZZ_2, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MLFSGASTAK PKKDEKKDKK SDRDPKNELQ EWVFVRWANH LLGTERLTDY
60 70 80 90 100
KSLQDGSNAI FVYQAIIGQT MAVLGNPSDD WPNVLQNIGD SKTNPQEVME
110 120 130 140 150
GQQKAVLSAW WQLVQFFWKN NAPVQLREEK LSEAIKQWCI EVMKSYEEID
160 170 180 190 200
VYDFTSSFRD GHAFNYLIHS YDRKLINLTK TAEMSAIDRI ENAFAVAEKT
210 220 230 240 250
WNVPRLLNPK DLHSDQLDSH SVLCYLMSLY LAMISTSKIE TELEAQQIQQ
260 270 280 290 300
QKVAALLASH KMLSSQPSTS SSSALQIPPQ TPPTAHHQAM LDRGKSFEQS
310 320 330 340 350
AEGEVRSRKS SSSSQKSGKS KKARREEQLA EFKSCIEQVL TWLLEAEDEL
360 370 380 390 400
TTLTQMPRVE LASVRSQFSD FESFMSSLTD SQDTVGRVLL RGQMLSNKSE
410 420 430 440 450
SEEEKESIGA NLHLVNTRWE ALREQAMQEQ AVLQQQIHLL QQSELDTISQ
460 470 480 490 500
WLDAAELEIE SFGPLAADSS QALRQIELHT KFQQKLNDFQ ETIDKLESFV
510 520 530 540 550
AVVDEENDAS VATLEDALSA VSVRWGHVCE WAEKRATKLD GLADLLDKTN
560 570 580 590 600
EVFENLSGWL AERENELMTG LKSAHHLENE EQVAQQVRRL QKTEEQLEQE
610 620 630 640 650
HASFVRLSQL SCELVGRLDD SNGAAANAVR LSLDSITQRW DNLVARIEEH
660 670 680 690 700
GKTLVKSGKA DVKQVQESQN EQKEQPASSE GLSTDTEGEE QKNQLVDKFL
710 720 730 740 750
LHISKLSHEL EPLQDWSEKF EVSRKKDDIR KMMNTCQEKL IQIKEQEARV
760 770 780 790 800
NRLQLELEHL HVAKLNARQL KRANDAFEQF AKGWARIVTK ISEAMNVLTG
810 820 830 840 850
QEAGGNGNGS EEAAVAAKIE QWIEAVDKVI NELSQLPVNE RRSRIDKLEQ
860 870 880 890 900
QLQVQDKNVG FIEKDLLKKA ILKKGLEIAG KRLAALKVEE KPVEKEEQLV
910 920 930 940 950
LSNSEEPEAE KHVTFVQETT EKPAPLQEPT SEAQLLEELD GPWSRVGDVV
960 970 980 990 1000
AIEHDLLRAK RAVDTARNSQ MSNETVEKAE TRKAEMEEKR RVTMSARSKF
1010 1020 1030 1040 1050
RMAEETLEEI ERNLDRLQVS DLEIADLVRG LEQEAAKLGE RVSQRKEAER
1060 1070 1080 1090 1100
TAEKILSMDD DEISQEIVIK TKDSTEKLIK RWNQLELDLE ENLRKAKRDQ
1110 1120 1130 1140 1150
DVFIQKRLRE GEEALNEIKT AIEGKRESLD AETAAENLDH LESSLDNISS
1160 1170 1180 1190 1200
LFGEIGSLPM DDNSREKLSK LAKAKDQITA RANEALAALT RTVSECEDFE
1210 1220 1230 1240 1250
KQIMLFQNWS ARIGFLLQAR KSADISAFDI PHEYHEDLGN EAELIPKLSR
1260 1270 1280 1290 1300
EFEEWTVKLN EMNSTATEKD DSARMREQLN HANETMAELK RKFNEFKRPK
1310 1320 1330 1340 1350
GFEEKLEKVI TTLSNVEMGL DDTTGIDGSE CGGALMEVRA LVRMLDGAQE
1360 1370 1380 1390 1400
KWKDLAENRE QLVKDRVLDE ETSKETLQKL QYAKTKSKEL YERSSTCIER
1410 1420 1430 1440 1450
LEDCVEMYQR LKMESDEIER FLEEMEGKLD QYAASDRPEE AEIVNELISE
1460 1470 1480 1490 1500
WNRNEAAMKN AEHLQRQLNE RAIKIPDDVL SLKRLRADAL KNRLNSWCRT
1510 1520 1530 1540 1550
IQEMSEDDES ALLEIDELHQ NLEKELKLVS DKEPSKIAEK LRFLRADRDR
1560 1570 1580 1590 1600
LSSRTRKLAA KNPRLAATSS DVLAGLNQKW KELEVKASAE KAPAPELRDA
1610 1620 1630 1640 1650
RLSSPSEQPF DKRVQELCDL FENLEAQLDF NGSPVSMVTE YQKRVENLDE
1660 1670 1680 1690 1700
YLDEYRPALD DTIEEGRKIA ETGRLELQTH SAIEKLDELT NRIEQVEVEL
1710 1720 1730 1740 1750
DKHRDKVPSL VEQHEQLKKD IDSFLLVLDV FTDRNLDDVD IAKSTRKELA
1760 1770 1780 1790 1800
ERDSHIVSLT SRATAIHCAL PGKGPQLHDV TLDKLRDRIE KLEARLSATE
1810 1820 1830 1840 1850
KKPVETVKST IPDRPEVPEE PEKSSPDRTS RSSLQLAMEA YGTATEDDSV
1860 1870 1880 1890 1900
ISEAVTVGQK SVDQVDPVEQ LEPVEPVEPK LEVKQLKDEA TEEEEKRTII
1910 1920 1930 1940 1950
LPDETEKVIE TIPAARPSAG PSEGTVAEVS TSEILKARPA QESIERTVRE
1960 1970 1980 1990 2000
VPVDEYEETA NISSGDELQD HKISSAVPDS ESEIASMFEV LDSIEDSHTN
2010 2020 2030 2040 2050
FEEFPFDYLD SADDDLKKTL LKLESCEKTL AKNEMTINIA QAENARERIT
2060 2070 2080 2090 2100
MLRQMALQRK DKLPKFNEEW NAMQELIQLA DALVDEAERY ESDQIPQMDR
2110 2120 2130 2140 2150
KSAPNVLGEL RKRVANAEGP VIDLVKKLSQ LVPRMQEDSP KSQDIRQKVY
2160 2170 2180 2190 2200
GIEDRFRRVG QAEGAAISKA LSSALTEPEL KLELDEVVRW CEMAEKEAAQ
2210 2220 2230 2240 2250
NVNSLDGDGL EKLDGRLAQF TKELQERKDD MVQLEMAKNM IIPSLKGDAH
2260 2270 2280 2290 2300
HDLRRNFSDT AKRVAMVRDE LSDAHKWVAT SRDTCDTFWA DIDSLEQLAR
2310 2320 2330 2340 2350
DVVRRANGIR MAVIYTPSRE NVEGVLRDVQ RLKMSIGDVK KRVQTANLPP
2360 2370 2380 2390 2400
AIKLAGKNAK RVVQVLTETA TTIADCHDIP TYLIDEMNDS GGDTTESRST
2410 2420 2430 2440 2450
VVEMTSVHTK QSSSSSSNKT PSAGGESDDA HTLNGDDEQS EEDQKIYSRE
2460 2470 2480 2490 2500
SSSTLPRGVS SLGSTGSSGV LDPVAVQLTH TRHWLHDVER DASITVDLAQ
2510 2520 2530 2540 2550
WQPARELWQS IQGIIDEIRL RSVHVTGAHD ASPNRQVRQQ AAQLLTEMRR
2560 2570 2580 2590 2600
TIENCEKRCL ILNQISDIAR QNEASRNEME LWLKSASDVI GERRVEELSE
2610 2620 2630 2640 2650
EVVRQELQVL ERVVEQLTER KDKMAEINSQ ANKIVDTYTK DEAHNLSHLL
2660 2670 2680 2690 2700
SRLNMSWTKF NDNIRIRRAV LEASLRSRRD FHSALSEFEK WLSRQEDNCS
2710 2720 2730 2740 2750
KLSADTSNHQ AIKDTSKRKN WTQSFKTLNA ELNAHEDVMK SVEKMGKMLA
2760 2770 2780 2790 2800
ESLESGNEKV ELLKRVGETT RRWTALRKTT NEIGERLEKA EQEWEKLSDG
2810 2820 2830 2840 2850
LADLLSWVEA KKQAIMDEQP TGGSLSAVMQ QASFVKGLQR EIESKTANYK
2860 2870 2880 2890 2900
STVEEAHSFL MQHDLRPKLH SPHVLDDDYE KEELANLEQR RRGLEINANC
2910 2920 2930 2940 2950
ERLKKNWAEL GIEVESWDKL VQHAMQRLQE LERNLAECQL HLTSSENEIE
2960 2970 2980 2990 3000
TMKAVEKIHL EDLKIAREET DQISKRIDEV RLFVDDVNDA AARLLAEDLK
3010 3020 3030 3040 3050
LDEHAKGQIE HVNKRYSTLK RAIRIRQAAV RNAASDFGPT SEHFLNQSVT
3060 3070 3080 3090 3100
LPWQRAISKS NLLPYYIEQT SEKTQWEHPV WVEIVKELSQ FNRVKFLAYR
3110 3120 3130 3140 3150
TAMKLRALQK RLCLDLVDLT LLEKAFVRLK GLSAEECPGL EGMVCALLPM
3160 3170 3180 3190 3200
YEALHAKYPN QVQSVSLAVD ICINFLLNLF DQSRDGIMRV LSFKIAMIVF
3210 3220 3230 3240 3250
SNIPLEEKYR YLFKLVSQDG HATQKQIALL LYDLIHIPRL VGESAAFGGT
3260 3270 3280 3290 3300
NVEPSVRSCF ETVRLAPTIS EGAFIDWVKK EPQSIVWLAV MHRLVISEST
3310 3320 3330 3340 3350
KHASKCNVCK MFPIIGIRYR CLTCFNCDLC QNCFFSQRTA KSHRTNHPMQ
3360 3370 3380 3390 3400
EYCEKTTSSD DARDFAKMIR NKFRASKRQK GYLPIDVAEE GIPLTCPPAK
3410 3420 3430 3440 3450
VTNQATEQMN ADTSQMTAHL AKLSAEHGGG AEHMEPVQSP LQIINQVEQL
3460 3470 3480 3490 3500
QRDEMDQMLH RLQFENKQLR KELEWKRGAA STMEIDRSSK RHQERHQSES
3510 3520 3530 3540 3550
RGGTLPLRNG RSVVSLKSTQ SQNDVMDEAK ALRLHKQRLE HRSRILEQQN
3560 3570 3580 3590 3600
EQLEMQLQRL KKVIDAQKQQ APLSTNSLLR GSHHQPWSPE RARSGSASTL
3610 3620 3630 3640 3650
DRGLIVSSRH QEQAEAAGGG AEDSSDEAGG AGGGPRGSSV GQMQNLMTAC
3660 3670
DDLGKAMESL VVSVVYDSDD EEND
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketV6CLV8 | V6CLV8_CAEEL | Dystrophin-1 | dys-1 CELE_F15D3.1, F15D3.1 | 3,663 | Annotation score: | ||
V6CJD7 | V6CJD7_CAEEL | Dystrophin-1 | dys-1 CELE_F15D3.1, F15D3.1 | 3,448 | Annotation score: | ||
V6CKJ6 | V6CKJ6_CAEEL | Dystrophin-1 | dys-1 CELE_F15D3.1, F15D3.1 | 2,515 | Annotation score: | ||
V6CLR8 | V6CLR8_CAEEL | Dystrophin-1 | dys-1 CELE_F15D3.1, F15D3.1 | 3,437 | Annotation score: | ||
V6CLW7 | V6CLW7_CAEEL | Dystrophin-1 | dys-1 CELE_F15D3.1, F15D3.1 | 1,577 | Annotation score: | ||
V6CJE3 | V6CJE3_CAEEL | Dystrophin-1 | dys-1 CELE_F15D3.1, F15D3.1 | 2,504 | Annotation score: | ||
V6CIR0 | V6CIR0_CAEEL | Dystrophin-1 | dys-1 CELE_F15D3.1, F15D3.1 | 149 | Annotation score: | ||
V6CL65 | V6CL65_CAEEL | Dystrophin-1 | dys-1 CELE_F15D3.1, F15D3.1 | 220 | Annotation score: |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_051614 | 1 – 3410 | Missing in isoform b. CuratedAdd BLAST | 3410 | |
Alternative sequenceiVSP_051615 | 3411 – 3446 | ADTSQ…QIINQ → MCSLLKLLKISGKSVSDDDP IERYIKCEQCKCKRHW in isoform b. CuratedAdd BLAST | 36 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ012469 mRNA Translation: CAA10033.1 Z81063, Z81522 Genomic DNA Translation: CAB61012.2 Z81522 Genomic DNA Translation: CAB61004.1 |
PIRi | T21635 |
RefSeqi | NP_492946.1, NM_060545.5 [Q9TW65-1] NP_492947.1, NM_060546.6 [Q9TW65-2] |
Genome annotation databases
EnsemblMetazoai | F15D3.1a.1; F15D3.1a.1; WBGene00001131 [Q9TW65-1] F15D3.1b.1; F15D3.1b.1; WBGene00001131 [Q9TW65-2] |
GeneIDi | 173038 |
UCSCi | F15D3.1b, c. elegans [Q9TW65-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ012469 mRNA Translation: CAA10033.1 Z81063, Z81522 Genomic DNA Translation: CAB61012.2 Z81522 Genomic DNA Translation: CAB61004.1 |
PIRi | T21635 |
RefSeqi | NP_492946.1, NM_060545.5 [Q9TW65-1] NP_492947.1, NM_060546.6 [Q9TW65-2] |
3D structure databases
SMRi | Q9TW65 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 38445, 6 interactors |
IntActi | Q9TW65, 3 interactors |
STRINGi | 6239.F15D3.1a |
Protein family/group databases
TCDBi | 8.A.66.1.1, the dystrophin (dystrophin) family |
PTM databases
iPTMneti | Q9TW65 |
Proteomic databases
EPDi | Q9TW65 |
PaxDbi | Q9TW65 |
PeptideAtlasi | Q9TW65 |
PRIDEi | Q9TW65 |
Genome annotation databases
EnsemblMetazoai | F15D3.1a.1; F15D3.1a.1; WBGene00001131 [Q9TW65-1] F15D3.1b.1; F15D3.1b.1; WBGene00001131 [Q9TW65-2] |
GeneIDi | 173038 |
UCSCi | F15D3.1b, c. elegans [Q9TW65-1] |
Organism-specific databases
CTDi | 173038 |
WormBasei | F15D3.1a ; CE27129 ; WBGene00001131 ; dys-1 F15D3.1b ; CE24904 ; WBGene00001131 ; dys-1 |
Phylogenomic databases
eggNOGi | KOG4286, Eukaryota |
HOGENOMi | CLU_000246_3_0_1 |
InParanoidi | Q9TW65 |
OMAi | NQRWDAI |
OrthoDBi | 629209at2759 |
PhylomeDBi | Q9TW65 |
Miscellaneous databases
PROi | PR:Q9TW65 |
Gene expression databases
Bgeei | WBGene00001131, Expressed in multi-cellular organism and 5 other tissues |
ExpressionAtlasi | Q9TW65, baseline and differential |
Family and domain databases
CDDi | cd00014, CH, 1 hit cd00201, WW, 1 hit |
Gene3Di | 1.10.418.10, 1 hit 3.30.60.90, 1 hit |
InterProi | View protein in InterPro IPR001589, Actinin_actin-bd_CS IPR001715, CH-domain IPR036872, CH_dom_sf IPR011992, EF-hand-dom_pair IPR015153, EF-hand_dom_typ1 IPR015154, EF-hand_dom_typ2 IPR018159, Spectrin/alpha-actinin IPR002017, Spectrin_repeat IPR001202, WW_dom IPR036020, WW_dom_sf IPR013087, Znf_C2H2_type IPR000433, Znf_ZZ IPR043145, Znf_ZZ_sf |
Pfami | View protein in Pfam PF00307, CH, 1 hit PF09068, EF-hand_2, 1 hit PF09069, EF-hand_3, 1 hit PF00435, Spectrin, 2 hits PF00569, ZZ, 1 hit |
SMARTi | View protein in SMART SM00033, CH, 1 hit SM00150, SPEC, 7 hits SM00456, WW, 1 hit SM00291, ZnF_ZZ, 1 hit |
SUPFAMi | SSF47473, SSF47473, 2 hits SSF47576, SSF47576, 1 hit SSF51045, SSF51045, 1 hit |
PROSITEi | View protein in PROSITE PS00019, ACTININ_1, 1 hit PS50021, CH, 1 hit PS01159, WW_DOMAIN_1, 1 hit PS50020, WW_DOMAIN_2, 1 hit PS50135, ZF_ZZ_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DMD_CAEEL | |
Accessioni | Q9TW65Primary (citable) accession number: Q9TW65 Secondary accession number(s): Q9TYG9, Q9U3H3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 25, 2004 |
Last sequence update: | October 1, 2001 | |
Last modified: | September 29, 2021 | |
This is version 159 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Caenorhabditis annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Caenorhabditis elegans
Caenorhabditis elegans: entries, gene names and cross-references to WormBase