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Protein
Submitted name:

Tumor necrosis factor alpha

Gene

TNF-alpha

Organism
Aotus lemurinus (Gray-bellied night monkey)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor alphaImported
Gene namesi
Name:TNF-alphaImported
OrganismiAotus lemurinus (Gray-bellied night monkey)Imported
Taxonomic identifieri43147 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniAotidaeAotus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneSAAS annotation

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ9TTG7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 137TNF_2InterPro annotationAdd BLAST132

Sequence similaritiesi

Belongs to the tumor necrosis factor family.SAAS annotation

Phylogenomic databases

HOVERGENiHBG012516

Family and domain databases

Gene3Di2.60.120.40, 1 hit
InterProiView protein in InterPro
IPR006053 TNF
IPR002959 TNF_alpha
IPR021184 TNF_CS
IPR006052 TNF_dom
IPR008983 Tumour_necrosis_fac-like_dom
PANTHERiPTHR11471:SF23 PTHR11471:SF23, 1 hit
PfamiView protein in Pfam
PF00229 TNF, 1 hit
PRINTSiPR01234 TNECROSISFCT
PR01235 TNFALPHA
SMARTiView protein in SMART
SM00207 TNF, 1 hit
SUPFAMiSSF49842 SSF49842, 1 hit
PROSITEiView protein in PROSITE
PS00251 TNF_1, 1 hit
PS50049 TNF_2, 1 hit

Sequencei

Sequence statusi: Fragment.

Q9TTG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PSDKPVAHVV ANPQAEGQLQ WLNRRANALL ANGVELRDNQ LVVPSEGLYL
60 70 80 90 100
VYSQVLFKGQ GCPSTFMLLT HSISRIAVSY QAKVNLLSAI KSPCQRETPR
110 120 130
GAKTNPWYEP IYLGGVFQLE KGDRLSAEIN LPDYLDFG
Length:138
Mass (Da):15,269
Last modified:May 1, 2000 - v1
Checksum:i29275EE4F4CD5068
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF097329 mRNA Translation: AAF21304.1

Similar proteinsi

Entry informationi

Entry nameiQ9TTG7_AOTLE
AccessioniPrimary (citable) accession number: Q9TTG7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 25, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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