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UniProtKB - Q9T1V0 (S1_BPMU)
Protein
Tail fiber protein S
Gene
S
Organism
Escherichia phage Mu (Bacteriophage Mu)
Status
Functioni
Component of the tail fiber that acts as receptor binding protein. Binds to the primary receptor, thereby determining the host range. Two alternate tail fiber S and S' proteins are encoded extending the host range of the virus.
1 PublicationMiscellaneous
The orientation of the G segment is defined as G+ and G-. G+ orientation provides S-U fibers whereas G- provides S'-U' fibers. S-U and S'-U' dont have the same host range (e.g. respectively E.coli and C.freundii).
GO - Biological processi
- adhesion receptor-mediated virion attachment to host cell Source: UniProtKB-KW
- viral entry into host cell Source: UniProtKB-KW
- viral tropism switching Source: UniProtKB-KW
Keywordsi
Biological process | Host-virus interaction, Viral attachment to host adhesion receptor, Viral attachment to host cell, Viral receptor tropism switching, Virus entry into host cell |
Names & Taxonomyi
Protein namesi | Recommended name: Tail fiber protein SAlternative name(s): Gene product 49 Short name: gp49 Gene product S Short name: gpS |
Gene namesi | Name:S Ordered Locus Names:Mup49 |
Organismi | Escherichia phage Mu (Bacteriophage Mu) |
Taxonomic identifieri | 10677 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes › Caudovirales › Myoviridae › Muvirus |
Virus hosti | Enterobacteriaceae [TaxID: 543] |
Proteomesi |
|
Subcellular locationi
- Virion 1 Publication
- Host cytoplasm 1 Publication Note: Tail fiber.
Keywords - Cellular componenti
Host cytoplasm, Viral tail fiber protein, Viral tail protein, VirionPathology & Biotechi
Disruption phenotypei
Viral particles lack tail fibers in inversion-defective gin mutants (blocked in G+ orientation; no switch to S'-U').1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000077693 | 1 – 504 | Tail fiber protein SAdd BLAST | 504 |
Expressioni
Inductioni
Expressed in the late phase of the viral replicative cycle. Expression of late genes is activated by the viral late transcription activator C. Expressed alternatively with tail fiber protein S' (associated with tail fiber assembly protein U'). The switch from S-U to S'-U' occurs through inversion of a DNA segment called G by the phage invertase protein Gin.1 Publication
Keywords - Developmental stagei
Late proteinStructurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q9T1V0 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the caudovirales tail fiber protein family.Curated
Family and domain databases
InterProi | View protein in InterPro IPR005068, Phage_lambda_Stf-r2 |
Pfami | View protein in Pfam PF03406, Phage_fiber_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9T1V0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFYIDNDSGV TVMPPVSAQR SAIVRWFSEG DGNNVITWPG MDWFNIVQAE
60 70 80 90 100
LLNTLEEAGI QPDKTKLNQL ALSIKAIMSN NALLIKNNLS EIKTAGASAQ
110 120 130 140 150
RTARENLDIY DASLNKKGLV QLTSATDSPS ETLAATAKAV KIAMDNANAR
160 170 180 190 200
LAKDRNGADI PNKPLFIQNL GLQETVNRAR NAVQKNGDTL SGGLTFENDS
210 220 230 240 250
ILAWIRNTDW AKIGFKNDAD SDTDSYMWFE TGDNGNEYFK WRSKQSTTTK
260 270 280 290 300
DLMNLKWDAL SVLVNAIVNG EVISKSANGL RIAYGNYGFF IRNDGSNTYF
310 320 330 340 350
MLTNSGDNMG TYNGLRPLWI NNATGAVSMG RGLNVSGDTL SDRFAINSSN
360 370 380 390 400
GMWIQMRDNN AIFGKNIVNT DSAQALLRQN HADRKFMIGG LGNKQFGIYM
410 420 430 440 450
INNSRTANGT DGQAYMDNNG NWLCGAQVIP GNYANFDSRY VRDVRLGTQS
460 470 480 490 500
LTGGLSRDYK APSGHVITGF HTNGDWEMQG GDDKVYIRPV QKNINGTWYN
VASA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF083977 Genomic DNA Translation: AAF01127.1 |
RefSeqi | NP_050653.1, NC_000929.1 |
Genome annotation databases
GeneIDi | 2636293 |
KEGGi | vg:2636293 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF083977 Genomic DNA Translation: AAF01127.1 |
RefSeqi | NP_050653.1, NC_000929.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5YVQ | X-ray | 2.10 | A | 1-504 | [»] | |
SMRi | Q9T1V0 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Genome annotation databases
GeneIDi | 2636293 |
KEGGi | vg:2636293 |
Family and domain databases
InterProi | View protein in InterPro IPR005068, Phage_lambda_Stf-r2 |
Pfami | View protein in Pfam PF03406, Phage_fiber_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | S1_BPMU | |
Accessioni | Q9T1V0Primary (citable) accession number: Q9T1V0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 23, 2022 | |
This is version 73 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families