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UniProtKB - Q9SZP1 (MYB4_ARATH)
Protein
Transcription repressor MYB4
Gene
MYB4
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Transcription repressor involved in regulation of protection against UV. Mediates transcriptional repression of CYP73A5, the gene encoding trans-cinnamate 4-monooxygenase, thereby regulating the accumulation of the UV-protectant compound sinapoylmalate.
1 PublicationRegions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 37 – 61 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 25 | |
DNA bindingi | 89 – 112 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 24 |
GO - Molecular functioni
- DNA binding Source: TAIR
- DNA-binding transcription factor activity Source: TAIR
- transcription cis-regulatory region binding Source: TAIR
GO - Biological processi
- negative regulation of sinapate ester biosynthetic process Source: TAIR
- negative regulation of transcription, DNA-templated Source: TAIR
- regulation of phenylpropanoid metabolic process Source: TAIR
- response to UV-B Source: TAIR
Keywordsi
Molecular function | DNA-binding, Repressor |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription repressor MYB4Alternative name(s): Myb-related protein 4 Short name: AtMYB4 |
Gene namesi | Name:MYB4 Ordered Locus Names:At4g38620 ORF Names:F20M13.180 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G38620 |
TAIRi | locus:2121259, AT4G38620 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPathology & Biotechi
Disruption phenotypei
Defects lead to a better tolerance of UV-B irradiation due to the increase in sinapate ester accumulation.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000197075 | 1 – 282 | Transcription repressor MYB4Add BLAST | 282 |
Proteomic databases
PaxDbi | Q9SZP1 |
ProteomicsDBi | 251002 |
Expressioni
Tissue specificityi
Widely expressed at low level. Highly expressed in siliques. Weakly expressed in seedlings, young and mature leaves, cauline leaves, stems, flower buds and roots.1 Publication
Inductioni
Down-regulated by exposure to UV-B light.1 Publication
Gene expression databases
ExpressionAtlasi | Q9SZP1, baseline and differential |
Genevisiblei | Q9SZP1, AT |
Interactioni
Subunit structurei
Protein-protein interaction databases
BioGRIDi | 15298, 6 interactors |
IntActi | Q9SZP1, 4 interactors |
STRINGi | 3702.AT4G38620.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 9 – 61 | HTH myb-type 1PROSITE-ProRule annotationAdd BLAST | 53 | |
Domaini | 62 – 116 | HTH myb-type 2PROSITE-ProRule annotationAdd BLAST | 55 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 119 – 145 | DisorderedSequence analysisAdd BLAST | 27 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 125 – 145 | Polar residuesSequence analysisAdd BLAST | 21 |
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | KOG0048, Eukaryota |
HOGENOMi | CLU_028567_23_0_1 |
InParanoidi | Q9SZP1 |
OMAi | ETFHESI |
OrthoDBi | 1499244at2759 |
PhylomeDBi | Q9SZP1 |
Family and domain databases
CDDi | cd00167, SANT, 2 hits |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017930, Myb_dom IPR001005, SANT/Myb |
Pfami | View protein in Pfam PF00249, Myb_DNA-binding, 2 hits |
SMARTi | View protein in SMART SM00717, SANT, 2 hits |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS51294, HTH_MYB, 2 hits |
i Sequence
Sequence statusi: Complete.
Q9SZP1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGRSPCCEKA HTNKGAWTKE EDERLVAYIK AHGEGCWRSL PKAAGLLRCG
60 70 80 90 100
KSCRLRWINY LRPDLKRGNF TEEEDELIIK LHSLLGNKWS LIAGRLPGRT
110 120 130 140 150
DNEIKNYWNT HIRRKLINRG IDPTSHRPIQ ESSASQDSKP TQLEPVTSNT
160 170 180 190 200
INISFTSAPK VETFHESISF PGKSEKISML TFKEEKDECP VQEKFPDLNL
210 220 230 240 250
ELRISLPDDV DRLQGHGKST TPRCFKCSLG MINGMECRCG RMRCDVVGGS
260 270 280
SKGSDMSNGF DFLGLAKKET TSLLGFRSLE MK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 141 | T → I in AAC83582 (PubMed:9839469).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF062860 mRNA Translation: AAC83582.1 AL035540 Genomic DNA Translation: CAB37518.1 AL161593 Genomic DNA Translation: CAB80526.1 CP002687 Genomic DNA Translation: AEE86955.1 AY519615 mRNA Translation: AAS10085.1 AY070100 mRNA Translation: AAL49837.1 AY123004 mRNA Translation: AAM67537.1 AY140037 mRNA Translation: AAM98178.1 BT006302 mRNA Translation: AAP13410.1 Z95763 mRNA Translation: CAB09195.1 |
PIRi | T05690 T51632 |
RefSeqi | NP_195574.1, NM_120023.3 |
Genome annotation databases
EnsemblPlantsi | AT4G38620.1; AT4G38620.1; AT4G38620 |
GeneIDi | 830018 |
Gramenei | AT4G38620.1; AT4G38620.1; AT4G38620 |
KEGGi | ath:AT4G38620 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF062860 mRNA Translation: AAC83582.1 AL035540 Genomic DNA Translation: CAB37518.1 AL161593 Genomic DNA Translation: CAB80526.1 CP002687 Genomic DNA Translation: AEE86955.1 AY519615 mRNA Translation: AAS10085.1 AY070100 mRNA Translation: AAL49837.1 AY123004 mRNA Translation: AAM67537.1 AY140037 mRNA Translation: AAM98178.1 BT006302 mRNA Translation: AAP13410.1 Z95763 mRNA Translation: CAB09195.1 |
PIRi | T05690 T51632 |
RefSeqi | NP_195574.1, NM_120023.3 |
3D structure databases
SMRi | Q9SZP1 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 15298, 6 interactors |
IntActi | Q9SZP1, 4 interactors |
STRINGi | 3702.AT4G38620.1 |
Proteomic databases
PaxDbi | Q9SZP1 |
ProteomicsDBi | 251002 |
Genome annotation databases
EnsemblPlantsi | AT4G38620.1; AT4G38620.1; AT4G38620 |
GeneIDi | 830018 |
Gramenei | AT4G38620.1; AT4G38620.1; AT4G38620 |
KEGGi | ath:AT4G38620 |
Organism-specific databases
Araporti | AT4G38620 |
TAIRi | locus:2121259, AT4G38620 |
Phylogenomic databases
eggNOGi | KOG0048, Eukaryota |
HOGENOMi | CLU_028567_23_0_1 |
InParanoidi | Q9SZP1 |
OMAi | ETFHESI |
OrthoDBi | 1499244at2759 |
PhylomeDBi | Q9SZP1 |
Miscellaneous databases
PROi | PR:Q9SZP1 |
Gene expression databases
ExpressionAtlasi | Q9SZP1, baseline and differential |
Genevisiblei | Q9SZP1, AT |
Family and domain databases
CDDi | cd00167, SANT, 2 hits |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017930, Myb_dom IPR001005, SANT/Myb |
Pfami | View protein in Pfam PF00249, Myb_DNA-binding, 2 hits |
SMARTi | View protein in SMART SM00717, SANT, 2 hits |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS51294, HTH_MYB, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | MYB4_ARATH | |
Accessioni | Q9SZP1Primary (citable) accession number: Q9SZP1 Secondary accession number(s): O49774, Q7DLI1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 21, 2004 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 23, 2022 | |
This is version 145 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names