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Protein

Probable WRKY transcription factor 19

Gene

WRKY19

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. May act also as a disease resistance protein with a serine/threonine-protein kinase activity (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei1654ATPPROSITE-ProRule annotation1
Active sitei1758By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi462 – 526WRKY 1PROSITE-ProRule annotationAdd BLAST65
DNA bindingi635 – 700WRKY 2PROSITE-ProRule annotationAdd BLAST66
Nucleotide bindingi844 – 851ATPPROSITE-ProRule annotation8
Nucleotide bindingi1632 – 1640ATPPROSITE-ProRule annotation9

GO - Molecular functioni

  • ADP binding Source: InterPro
  • ATP binding Source: UniProtKB-KW
  • DNA-binding transcription factor activity Source: TAIR
  • protein serine/threonine kinase activity Source: UniProtKB-KW
  • sequence-specific DNA binding Source: GO_Central
  • transcription regulatory region DNA binding Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Kinase, Serine/threonine-protein kinase, Transferase
Biological processPlant defense, Transcription, Transcription regulation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-2871796 FCERI mediated MAPK activation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable WRKY transcription factor 19
Alternative name(s):
WRKY DNA-binding protein 19
Gene namesi
Name:WRKY19
Ordered Locus Names:At4g12020
ORF Names:F16J13.90
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G12020
TAIRilocus:2118116 AT4G12020

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001336611 – 1895Probable WRKY transcription factor 19Add BLAST1895

Proteomic databases

PaxDbiQ9SZ67
PRIDEiQ9SZ67

Expressioni

Gene expression databases

ExpressionAtlasiQ9SZ67 baseline and differential
GenevisibleiQ9SZ67 AT

Interactioni

Protein-protein interaction databases

BioGridi12108, 1 interactor
IntActiQ9SZ67, 1 interactor
STRINGi3702.AT4G12020.2

Structurei

3D structure databases

ProteinModelPortaliQ9SZ67
SMRiQ9SZ67
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini291 – 371PAHPROSITE-ProRule annotationAdd BLAST81
Domaini800 – 1087NB-ARCAdd BLAST288
Repeati1206 – 1227LRR 1Add BLAST22
Repeati1228 – 1249LRR 2Add BLAST22
Repeati1259 – 1281LRR 3Add BLAST23
Repeati1282 – 1304LRR 4Add BLAST23
Repeati1306 – 1328LRR 5Add BLAST23
Repeati1329 – 1351LRR 6Add BLAST23
Repeati1352 – 1371LRR 7Add BLAST20
Repeati1373 – 1395LRR 8Add BLAST23
Repeati1397 – 1419LRR 9Add BLAST23
Repeati1421 – 1442LRR 10Add BLAST22
Domaini1626 – 1877Protein kinasePROSITE-ProRule annotationAdd BLAST252

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi35 – 39Poly-Ser5
Compositional biasi87 – 90Poly-Ser4
Compositional biasi97 – 307Gly-richAdd BLAST211
Compositional biasi980 – 983Poly-Leu4
Compositional biasi1568 – 1571Poly-Ser4

Sequence similaritiesi

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG0198 Eukaryota
ENOG410XQGS LUCA
OrthoDBiEOG093603EG

Family and domain databases

Gene3Di2.20.25.80, 2 hits
3.40.50.10140, 1 hit
3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR011713 Leu-rich_rpt_3
IPR032675 LRR_dom_sf
IPR002182 NB-ARC
IPR027417 P-loop_NTPase
IPR003822 PAH
IPR036600 PAH_sf
IPR000719 Prot_kinase_dom
IPR035897 Toll_tir_struct_dom_sf
IPR036390 WH_DNA-bd_sf
IPR003657 WRKY_dom
IPR036576 WRKY_dom_sf
PfamiView protein in Pfam
PF07725 LRR_3, 1 hit
PF00931 NB-ARC, 1 hit
PF02671 PAH, 1 hit
PF00069 Pkinase, 1 hit
PF03106 WRKY, 2 hits
SMARTiView protein in SMART
SM00774 WRKY, 2 hits
SUPFAMiSSF118290 SSF118290, 2 hits
SSF46785 SSF46785, 1 hit
SSF47762 SSF47762, 1 hit
SSF52200 SSF52200, 1 hit
SSF52540 SSF52540, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51477 PAH, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS50811 WRKY, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9SZ67-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSEKEELPLT LTSIGAATAT SDYHQRVGSS GEGISSSSSD VDPRFMQNSP
60 70 80 90 100
TGLMISQSSS MCTVPPGMAA TPPISSGSGL SQQLNNSSSS KLCQVEGCQK
110 120 130 140 150
GARDASGRCI SHGGGRRCQK PDCQKGAEGK TVYCKAHGGG RRCEYLGCTK
160 170 180 190 200
GAEGSTDFCI AHGGGRRCNH EDCTRSAWGR TEFCVKHGGG ARCKTYGCGK
210 220 230 240 250
SASGPLPFCR AHGGGKKCSH EDCTGFARGR SGLCLMHGGG KRCQRENCTK
260 270 280 290 300
SAEGLSGLCI SHGGGRRCQS IGCTKGAKGS KMFCKACITK RPLTIDGGGN
310 320 330 340 350
MGGVTTGDAL NYLKAVKDKF EDSEKYDTFL EVLNDCKHQG VDTSGVIARL
360 370 380 390 400
KDLFKGHDDL LLGFNTYLSK EYQITILPED DFPIDFLDKV EGPYEMTYQQ
410 420 430 440 450
AQTVQANANM QPQTEYPSSS AVQSFSSGQP QIPTSAPDSS LLAKSNTSGI
460 470 480 490 500
TIIEHMSQQP LNVDKQVNDG YNWQKYGQKK VKGSKFPLSY YKCTYLGCPS
510 520 530 540 550
KRKVERSLDG QVAEIVYKDR HNHEPPNQGK DGSTTYLSGS STHINCMSSE
560 570 580 590 600
LTASQFSSNK TKIEQQEAAS LATTIEYMSE ASDNEEDSNG ETSEGEKDED
610 620 630 640 650
EPEPKRRITE VQVSELADAS DRTVREPRVI FQTTSEVDNL DDGYRWRKYG
660 670 680 690 700
QKVVKGNPYP RFSSSKDYDV VIRYGRADIS NEDFISHLRA SLCRRGISVY
710 720 730 740 750
EKFNEVDALP KCRVLIIVLT STYVPSNLLN ILEHQHTEDR VVYPIFYRLS
760 770 780 790 800
PYDFVCNSKN YERFYLQDEP KKWQAALKEI TQMPGYTLTD KSESELIDEI
810 820 830 840 850
VRDALKVLCS ADKVNMIGMD MQVEEILSLL CIESLDVRSI GIWGTVGIGK
860 870 880 890 900
TTIAEEIFRK ISVQYETCVV LKDLHKEVEV KGHDAVRENF LSEVLEVEPH
910 920 930 940 950
VIRISDIKTS FLRSRLQRKR ILVILDDVND YRDVDTFLGT LNYFGPGSRI
960 970 980 990 1000
IMTSRNRRVF VLCKIDHVYE VKPLDIPKSL LLLDRGTCQI VLSPEVYKTL
1010 1020 1030 1040 1050
SLELVKFSNG NPQVLQFLSS IDREWNKLSQ EVKTTSPIYI PGIFEKSCCG
1060 1070 1080 1090 1100
LDDNERGIFL DIACFFNRID KDNVAMLLDG CGFSAHVGFR GLVDKSLLTI
1110 1120 1130 1140 1150
SQHNLVDMLS FIQATGREIV RQESADRPGD RSRLWNADYI RHVFINDTGT
1160 1170 1180 1190 1200
SAIEGIFLDM LNLKFDANPN VFEKMCNLRL LKLYCSKAEE KHGVSFPQGL
1210 1220 1230 1240 1250
EYLPSKLRLL HWEYYPLSSL PKSFNPENLV ELNLPSSCAK KLWKGKKARF
1260 1270 1280 1290 1300
CTTNSSLEKL KKMRLSYSDQ LTKIPRLSSA TNLEHIDLEG CNSLLSLSQS
1310 1320 1330 1340 1350
ISYLKKLVFL NLKGCSKLEN IPSMVDLESL EVLNLSGCSK LGNFPEISPN
1360 1370 1380 1390 1400
VKELYMGGTM IQEIPSSIKN LVLLEKLDLE NSRHLKNLPT SIYKLKHLET
1410 1420 1430 1440 1450
LNLSGCISLE RFPDSSRRMK CLRFLDLSRT DIKELPSSIS YLTALDELLF
1460 1470 1480 1490 1500
VDSRRNSPVV TNPNANSTEL MPSESSKLEI LGTPADNEVV VGGTVEKTRG
1510 1520 1530 1540 1550
IERTPTILVK SREYLIPDDV VAVGGDIKGL RPPVLQLQPA MKLSHIPRGS
1560 1570 1580 1590 1600
TWDFVTHFAP PETVAPPSSS SEAREEEVET EETGAMFIPL GDKETCSFTV
1610 1620 1630 1640 1650
NKGDSSRTIS NTSPIYASEG SFITCWQKGQ LLGRGSLGSV YEGISADGDF
1660 1670 1680 1690 1700
FAFKEVSLLD QGSQAHEWIQ QVEGGIALLS QLQHQNIVRY RGTTKDESNL
1710 1720 1730 1740 1750
YIFLELVTQG SLRKLYQRNQ LGDSVVSLYT RQILDGLKYL HDKGFIHRNI
1760 1770 1780 1790 1800
KCANVLVDAN GTVKLADFGL AKVMSLWRTP YWNWMAPEVI LNPKDYDGYG
1810 1820 1830 1840 1850
TPADIWSLGC TVLEMLTGQI PYSDLEIGTA LYNIGTGKLP KIPDILSLDA
1860 1870 1880 1890
RDFILTCLKV NPEERPTAAE LLNHPFVNMP LPSSGSGSVS SLLRG
Length:1,895
Mass (Da):210,322
Last modified:May 1, 2000 - v1
Checksum:i1C19D3EE164C9363
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4JPV9F4JPV9_ARATH
Protein kinase family protein
WRKY19 ATWRKY19, ERK KINASE KINASE 4, MAPK, MAPKKK11, MEKK4
1,879Annotation score:
B3H4T8B3H4T8_ARATH
Protein kinase family protein
WRKY19 ATWRKY19, ERK KINASE KINASE 4, MAPK, MAPKKK11, MEKK4
1,798Annotation score:
A0A1P8B8D2A0A1P8B8D2_ARATH
Protein kinase family protein
WRKY19 ATWRKY19, ERK KINASE KINASE 4, MAPK, MAPKKK11, MEKK4
1,820Annotation score:
A0A1P8B8G5A0A1P8B8G5_ARATH
Protein kinase family protein
WRKY19 ATWRKY19, ERK KINASE KINASE 4, MAPK, MAPKKK11, MEKK4
1,871Annotation score:
A0A1P8B8D3A0A1P8B8D3_ARATH
Protein kinase family protein
WRKY19 ATWRKY19, ERK KINASE KINASE 4, MAPK, MAPKKK11, MEKK4
1,887Annotation score:
A0A1P8B8E0A0A1P8B8E0_ARATH
Protein kinase family protein
WRKY19 ATWRKY19, ERK KINASE KINASE 4, MAPK, MAPKKK11, MEKK4
1,790Annotation score:
A0A1P8B8D4A0A1P8B8D4_ARATH
Protein kinase family protein
WRKY19 ATWRKY19, ERK KINASE KINASE 4, MAPK, MAPKKK11, MEKK4
1,768Annotation score:
A0A1P8B8F0A0A1P8B8F0_ARATH
Protein kinase family protein
WRKY19 ATWRKY19, ERK KINASE KINASE 4, MAPK, MAPKKK11, MEKK4
1,261Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049638 Genomic DNA Translation: CAB40943.1
AL161533 Genomic DNA Translation: CAB78245.1
CP002687 Genomic DNA Translation: AEE83085.1
PIRiT06609
RefSeqiNP_001118968.1, NM_001125496.2 [Q9SZ67-1]
UniGeneiAt.3076

Genome annotation databases

EnsemblPlantsiAT4G12020.2; AT4G12020.2; AT4G12020 [Q9SZ67-1]
GeneIDi826810
GrameneiAT4G12020.2; AT4G12020.2; AT4G12020 [Q9SZ67-1]
KEGGiath:AT4G12020

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Web resourcesi

NIB-LRRS

Functional and comparative genomics of disease resistance gene homologs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049638 Genomic DNA Translation: CAB40943.1
AL161533 Genomic DNA Translation: CAB78245.1
CP002687 Genomic DNA Translation: AEE83085.1
PIRiT06609
RefSeqiNP_001118968.1, NM_001125496.2 [Q9SZ67-1]
UniGeneiAt.3076

3D structure databases

ProteinModelPortaliQ9SZ67
SMRiQ9SZ67
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi12108, 1 interactor
IntActiQ9SZ67, 1 interactor
STRINGi3702.AT4G12020.2

Proteomic databases

PaxDbiQ9SZ67
PRIDEiQ9SZ67

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G12020.2; AT4G12020.2; AT4G12020 [Q9SZ67-1]
GeneIDi826810
GrameneiAT4G12020.2; AT4G12020.2; AT4G12020 [Q9SZ67-1]
KEGGiath:AT4G12020

Organism-specific databases

AraportiAT4G12020
TAIRilocus:2118116 AT4G12020

Phylogenomic databases

eggNOGiKOG0198 Eukaryota
ENOG410XQGS LUCA
OrthoDBiEOG093603EG

Enzyme and pathway databases

ReactomeiR-ATH-2871796 FCERI mediated MAPK activation

Miscellaneous databases

PROiPR:Q9SZ67

Gene expression databases

ExpressionAtlasiQ9SZ67 baseline and differential
GenevisibleiQ9SZ67 AT

Family and domain databases

Gene3Di2.20.25.80, 2 hits
3.40.50.10140, 1 hit
3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR011713 Leu-rich_rpt_3
IPR032675 LRR_dom_sf
IPR002182 NB-ARC
IPR027417 P-loop_NTPase
IPR003822 PAH
IPR036600 PAH_sf
IPR000719 Prot_kinase_dom
IPR035897 Toll_tir_struct_dom_sf
IPR036390 WH_DNA-bd_sf
IPR003657 WRKY_dom
IPR036576 WRKY_dom_sf
PfamiView protein in Pfam
PF07725 LRR_3, 1 hit
PF00931 NB-ARC, 1 hit
PF02671 PAH, 1 hit
PF00069 Pkinase, 1 hit
PF03106 WRKY, 2 hits
SMARTiView protein in SMART
SM00774 WRKY, 2 hits
SUPFAMiSSF118290 SSF118290, 2 hits
SSF46785 SSF46785, 1 hit
SSF47762 SSF47762, 1 hit
SSF52200 SSF52200, 1 hit
SSF52540 SSF52540, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51477 PAH, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS50811 WRKY, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiWRK19_ARATH
AccessioniPrimary (citable) accession number: Q9SZ67
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: May 1, 2000
Last modified: November 7, 2018
This is version 160 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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