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Protein

Putative phospholipid-transporting ATPase 9

Gene

ALA9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in transport of phospholipids.1 Publication

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei4304-aspartylphosphate intermediateBy similarity1
Metal bindingi870MagnesiumBy similarity1
Metal bindingi874MagnesiumBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-6798695 Neutrophil degranulation
R-ATH-936837 Ion transport by P-type ATPases

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phospholipid-transporting ATPase 91 Publication (EC:3.6.3.11 Publication)
Short name:
AtALA91 Publication
Alternative name(s):
Aminophospholipid flippase 91 Publication
Gene namesi
Name:ALA91 Publication
Ordered Locus Names:At1g68710Imported
ORF Names:F24J5.6Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G68710
TAIRilocus:2026900 AT1G68710

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 75CytoplasmicSequence analysisAdd BLAST75
Transmembranei76 – 97HelicalSequence analysisAdd BLAST22
Topological domaini98 – 101ExtracellularSequence analysis4
Transmembranei102 – 124HelicalSequence analysisAdd BLAST23
Topological domaini125 – 306CytoplasmicSequence analysisAdd BLAST182
Transmembranei307 – 328HelicalSequence analysisAdd BLAST22
Topological domaini329 – 364ExtracellularSequence analysisAdd BLAST36
Transmembranei365 – 382HelicalSequence analysisAdd BLAST18
Topological domaini383 – 925CytoplasmicSequence analysisAdd BLAST543
Transmembranei926 – 945HelicalSequence analysisAdd BLAST20
Topological domaini946 – 959ExtracellularSequence analysisAdd BLAST14
Transmembranei960 – 979HelicalSequence analysisAdd BLAST20
Topological domaini980 – 1009CytoplasmicSequence analysisAdd BLAST30
Transmembranei1010 – 1032HelicalSequence analysisAdd BLAST23
Topological domaini1033 – 1045ExtracellularSequence analysisAdd BLAST13
Transmembranei1046 – 1068HelicalSequence analysisAdd BLAST23
Topological domaini1069 – 1074CytoplasmicSequence analysis6
Transmembranei1075 – 1095HelicalSequence analysisAdd BLAST21
Topological domaini1096 – 1112ExtracellularSequence analysisAdd BLAST17
Transmembranei1113 – 1137HelicalSequence analysisAdd BLAST25
Topological domaini1138 – 1200CytoplasmicSequence analysisAdd BLAST63

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000463931 – 1200Putative phospholipid-transporting ATPase 9Add BLAST1200

Proteomic databases

PaxDbiQ9SX33

PTM databases

iPTMnetiQ9SX33

Expressioni

Gene expression databases

ExpressionAtlasiQ9SX33 differential
GenevisibleiQ9SX33 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G68710.1

Structurei

3D structure databases

ProteinModelPortaliQ9SX33
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410ITKD Eukaryota
ENOG410XPYK LUCA
HOGENOMiHOG000202528
InParanoidiQ9SX33
KOiK01530
OMAiGFGELIM
OrthoDBiEOG0936012H
PhylomeDBiQ9SX33

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
PANTHERiPTHR24092 PTHR24092, 1 hit
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 3 hits
SSF81653 SSF81653, 2 hits
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 4 hits
TIGRFAMsiTIGR01652 ATPase-Plipid, 1 hit
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SX33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGGGTKRRR RRLQLSKLYT LTCAQACFKQ DHSQIGGPGF SRVVYCNEPD
60 70 80 90 100
SPEADSRNYS DNYVRTTKYT LATFLPKSLF EQFRRVANFY FLVTGVLAFT
110 120 130 140 150
PLAPYTASSA IVPLLFVIGA TMVKEGVEDW RRQKQDNEVN NRKVKVHRGD
160 170 180 190 200
GSFDAKEWKT LSIGDIVKVE KNEFFPADLV LLSSSYEDAI CYVETMNLDG
210 220 230 240 250
ETNLKVKQGL EVTSSLRDEF NFKGFEAFVK CEDPNANLYS FVGTMELKGA
260 270 280 290 300
KYPLSPQQLL LRDSKLRNTD FIFGAVIFTG HDTKVIQNST DPPSKRSMIE
310 320 330 340 350
KKMDKIIYLM FFMVITMAFI GSVIFGVTTR DDLKDGVMKR WYLRPDSSSI
360 370 380 390 400
FFDPKRAPVA AIYHFLTAVM LYSYFIPISL YVSIEIVKVL QSIFINQDIH
410 420 430 440 450
MYYEEADKPA RARTSNLNEE LGQVDTILSD KTGTLTCNSM EFIKCSVAGT
460 470 480 490 500
AYGRGVTEVE MAMGRRKGGP LVFQSDENDI DMEYSKEAIT EESTVKGFNF
510 520 530 540 550
RDERIMNGNW VTETHADVIQ KFFRLLAVCH TVIPEVDEDT EKISYEAESP
560 570 580 590 600
DEAAFVIAAR ELGFEFFNRT QTTISVRELD LVSGKRVERL YKVLNVLEFN
610 620 630 640 650
STRKRMSVIV QEEDGKLLLL CKGADNVMFE RLSKNGREFE EETRDHVNEY
660 670 680 690 700
ADAGLRTLIL AYRELDEKEY KVFNERISEA KSSVSADRES LIEEVTEKIE
710 720 730 740 750
KDLILLGATA VEDKLQNGVP DCIDKLAQAG IKIWVLTGDK METAINIGFA
760 770 780 790 800
CSLLRQDMKQ IIINLETPEI QSLEKTGEKD VIAKASKENV LSQIINGKTQ
810 820 830 840 850
LKYSGGNAFA LIIDGKSLAY ALDDDIKHIF LELAVSCASV ICCRSSPKQK
860 870 880 890 900
ALVTRLVKSG NGKTTLAIGD GANDVGMLQE ADIGVGISGV EGMQAVMSSD
910 920 930 940 950
IAIAQFRYLE RLLLVHGHWC YRRISTMICY FFYKNITFGF TLFLYETYTT
960 970 980 990 1000
FSSTPAYNDW FLSLYNVFFS SLPVIALGVF DQDVSARYCL KFPLLYQEGV
1010 1020 1030 1040 1050
QNVLFSWRRI LGWMFNGFYS AVIIFFLCKS SLQSQAFNHD GKTPGREILG
1060 1070 1080 1090 1100
GTMYTCIVWV VNLQMALAIS YFTLIQHIVI WSSIVVWYFF ITVYGELPSR
1110 1120 1130 1140 1150
ISTGAYKVFV EALAPSLSYW LITLFVVVAT LMPYFIYSAL QMSFFPMYHG
1160 1170 1180 1190 1200
MIQWLRYEGQ CNDPEYCDIV RQRSIRPTTV GFTARLEAKK RSVRISEPAS
Length:1,200
Mass (Da):136,045
Last modified:May 1, 2000 - v1
Checksum:iE8CAB216E2D2B261
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008075 Genomic DNA Translation: AAD49973.1
CP002684 Genomic DNA Translation: AEE34830.1
CP002684 Genomic DNA Translation: ANM58269.1
PIRiF96711
RefSeqiNP_001320717.1, NM_001334377.1
NP_177038.1, NM_105543.6
UniGeneiAt.52438

Genome annotation databases

EnsemblPlantsiAT1G68710.1; AT1G68710.1; AT1G68710
AT1G68710.2; AT1G68710.2; AT1G68710
GeneIDi843201
GrameneiAT1G68710.1; AT1G68710.1; AT1G68710
AT1G68710.2; AT1G68710.2; AT1G68710
KEGGiath:AT1G68710

Similar proteinsi

Entry informationi

Entry nameiALA9_ARATH
AccessioniPrimary (citable) accession number: Q9SX33
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 138 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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