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Protein

Protein PHYTOCHROME KINASE SUBSTRATE 1

Gene

PKS1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be responsible for light-regulated cytoplasmic sequestration of phytochromes or may be a negative regulator of phytochrome B signaling. Component of the network that modulates the very low-fluence response (VLFR) branch of phyA signaling. Acts positively in PHOT1 signaling. Regulates phytochrome-mediated photomorphogenesis and hypocotyl phototropism. Involved in the control of leaf flattening and leaf positioning. Promotes negative root phototropism and negatively regulates root gravitropism. May act by controlling auxin homeostasis.5 Publications

Miscellaneous

PKS1, PKS2 and/or PKS4 are essential for phototropism but not for inhibition of gravitropism under long-term blue light irradiation.

GO - Biological processi

  • phototropism Source: TAIR
  • positive gravitropism Source: TAIR
  • red, far-red light phototransduction Source: TAIR
  • red or far-red light signaling pathway Source: TAIR
  • response to far red light Source: TAIR
  • response to red light Source: TAIR

Keywordsi

Biological processPhytochrome signaling pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PHYTOCHROME KINASE SUBSTRATE 1
Gene namesi
Name:PKS1
Ordered Locus Names:At2g02950
ORF Names:T17M13.12
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G02950
TAIRilocus:2056695 AT2G02950

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Increased hypocotyl growth inhibition and cotyledon unfolding responses in the very low fluence response (VLFR) mode. Reduced phototropic response. Reduced hyponasty when grown under blue light. Loss of negative root phototropism. Auxin accumulation in protoplasts.4 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000584501 – 439Protein PHYTOCHROME KINASE SUBSTRATE 1Add BLAST439

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei238PhosphoserineBy similarity1
Modified residuei244PhosphoserineBy similarity1

Post-translational modificationi

Phosphorylated on Ser and to a lower extent on Thr by phytochromes. Phosphorylation is stimulated twofold by red light.2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9SWI1

PTM databases

iPTMnetiQ9SWI1

Expressioni

Tissue specificityi

Expressed in young seedlings in both darkness and light. Moderate in leaves and very low in roots and flowers. Expressed in the elongation zone of the root and hypocotyl.4 Publications

Developmental stagei

Decreases with development.1 Publication

Inductioni

Up-regulated by white, red, far-red and blue light.2 Publications

Gene expression databases

ExpressionAtlasiQ9SWI1 differential
GenevisibleiQ9SWI1 AT

Interactioni

Subunit structurei

Interacts with PKS2, RPT3, PHOT1, PHOT2 and the C-termini of both phytochromes A (phyA) and B (phyB). Binds both spectral forms of phytochrome, Pr and Pfr.4 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi225, 6 interactors
DIPiDIP-34783N
IntActiQ9SWI1, 7 interactors
STRINGi3702.AT2G02950.1

Structurei

3D structure databases

ProteinModelPortaliQ9SWI1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi31 – 34Poly-Ser4
Compositional biasi365 – 369Poly-Ser5

Sequence similaritiesi

Belongs to the PKS family.Curated

Phylogenomic databases

eggNOGiENOG410IXAU Eukaryota
ENOG4111ACR LUCA
HOGENOMiHOG000115571
InParanoidiQ9SWI1
OMAiFLMSCKS
OrthoDBiEOG09360DBV
PhylomeDBiQ9SWI1

Sequencei

Sequence statusi: Complete.

Q9SWI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTLTPSSAS TPKTSFDFMK NNNSHSSLYV SSSSYLSSKE DALVTTKKLM
60 70 80 90 100
EPSKTLNMSI NPKQEEFGDE KKMVKKAPED PEIGVFGAEK YFNGDMDSDQ
110 120 130 140 150
GSSVLSLTNP EVERTVVDSK QSAKKSTGTP SVRSESSWNS QSVLLQNKLV
160 170 180 190 200
NSCNSSFKEK KNSNGQIQKV TNNKKSFLAN LGCKCACSDG DSVDVEEKTS
210 220 230 240 250
VKRSADPNIS VITMRSSADM NTELIKIQKQ EELSQRKSLE VFGSPVAIEK
260 270 280 290 300
KSSVVQKKLP LPPWKSRTEE DDTKSEGSDS SSDLFEIEGL TGNPKPFLTR
310 320 330 340 350
QGSDPASPTC YAPSEVSVEW SIVTASAADF SVMSECATSP VRRNRPTQIP
360 370 380 390 400
RIPITAKSAP QRRKSSSSSG GNGFLMSCKS HKSVMVSGDL DRRSSMNKTQ
410 420 430
PSYVPRFPME TTKPKSFETR RRISNSSISH TQSSLLYSQ
Length:439
Mass (Da):48,085
Last modified:May 10, 2002 - v2
Checksum:i7A0A825FF7D3F3FC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti196E → D in AAD38033 (PubMed:10348744).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF149053 mRNA Translation: AAD38033.1
AC004138 Genomic DNA Translation: AAC32913.1
CP002685 Genomic DNA Translation: AEC05643.1
AF325064 mRNA Translation: AAK17132.1
AY052708 mRNA Translation: AAK96612.1
AY063721 mRNA Translation: AAL36071.1
PIRiE84442
T52304
RefSeqiNP_565292.1, NM_126347.3
UniGeneiAt.24751

Genome annotation databases

EnsemblPlantsiAT2G02950.1; AT2G02950.1; AT2G02950
GeneIDi814823
GrameneiAT2G02950.1; AT2G02950.1; AT2G02950
KEGGiath:AT2G02950

Similar proteinsi

Entry informationi

Entry nameiPKS1_ARATH
AccessioniPrimary (citable) accession number: Q9SWI1
Secondary accession number(s): O80610
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: May 10, 2002
Last modified: May 23, 2018
This is version 102 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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