UniProtKB - Q9SW97 (GLR35_ARATH)
Glutamate receptor 3.5
GLR3.5
Functioni
Glutamate-gated receptor that probably acts as non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
GO - Molecular functioni
- calcium channel activity Source: UniProtKB
- glutamate receptor activity Source: UniProtKB
- ligand-gated ion channel activity Source: GO_Central
- signaling receptor activity Source: GO_Central
GO - Biological processi
- calcium ion transport Source: UniProtKB
- calcium-mediated signaling Source: UniProtKB
- cellular response to amino acid stimulus Source: UniProtKB
Keywordsi
Molecular function | Ion channel, Ligand-gated ion channel, Receptor |
Biological process | Ion transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Glutamate receptor 3.5Alternative name(s): Ionotropic glutamate receptor GLR6 Ligand-gated ion channel 3.5 |
Gene namesi | Name:GLR3.5 Synonyms:GLR6 Ordered Locus Names:At2g32390 ORF Names:T32F6.9 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G32390 |
Subcellular locationi
Other locations
Plasma Membrane
- plasma membrane Source: UniProtKB
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 30 – 606 | ExtracellularSequence analysisAdd BLAST | 577 | |
Transmembranei | 607 – 627 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 628 – 636 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 637 – 657 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 658 – 668 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 669 – 689 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 690 – 850 | ExtracellularSequence analysisAdd BLAST | 161 | |
Transmembranei | 851 – 871 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 872 – 953 | CytoplasmicSequence analysisAdd BLAST | 82 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 29 | Sequence analysisAdd BLAST | 29 | |
ChainiPRO_0000011609 | 30 – 953 | Glutamate receptor 3.5Add BLAST | 924 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 38 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 95 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 223 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 371 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 397 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 436 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 454 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 569 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PRIDEi | Q9SW97 |
ProteomicsDBi | 247365 [Q9SW97-1] |
Expressioni
Tissue specificityi
Gene expression databases
ExpressionAtlasi | Q9SW97, baseline and differential |
Interactioni
Subunit structurei
May form heteromers.
By similarityProtein-protein interaction databases
STRINGi | 3702.AT2G32390.3 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 928 – 953 | DisorderedSequence analysisAdd BLAST | 26 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 937 – 953 | Polar residuesSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
InParanoidi | Q9SW97 |
OMAi | YHCNFRI |
OrthoDBi | 188544at2759 |
PhylomeDBi | Q9SW97 |
Family and domain databases
CDDi | cd19990, PBP1_GABAb_receptor_plant, 1 hit |
InterProi | View protein in InterPro IPR001828, ANF_lig-bd_rcpt IPR044440, GABAb_receptor_plant_PBP1 IPR001320, Iontro_rcpt IPR017103, Iontropic_Glu_rcpt_pln IPR028082, Peripla_BP_I IPR001638, Solute-binding_3/MltF_N |
Pfami | View protein in Pfam PF01094, ANF_receptor, 1 hit PF00060, Lig_chan, 1 hit PF00497, SBP_bac_3, 1 hit |
PIRSFi | PIRSF037090, Iontro_Glu-like_rcpt_pln, 1 hit |
SMARTi | View protein in SMART SM00079, PBPe, 1 hit |
SUPFAMi | SSF53822, SSF53822, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 1 produced by isoform ialternative splicing. AlignAdd to basketThis entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGFFVMIRDV SMGFMLLCIS ALWVLPIQGA GRESFSRNSS SSSLPSSVNV
60 70 80 90 100
GALFTYDSFI GRAAKLAFVA AIEDINADQS ILRGTKLNIV FQDTNCSGFV
110 120 130 140 150
GTMGALQLME NKVVAAIGPQ SSGIGHIISH VANELHVPFL SFAATDPTLS
160 170 180 190 200
SLQYPYFLRT TQNDYFQMNA ITDFVSYFRW REVVAIFVDD EYGRNGISVL
210 220 230 240 250
GDALAKKRAK ISYKAAFPPG ADNSSISDLL ASVNLMESRI FVVHVNPDSG
260 270 280 290 300
LNIFSVAKSL GMMGSGYVWI TTDWLLTALD SMEPLDPRAL DLLQGVVAFR
310 320 330 340 350
HYTPESDNKR QFKGRWKNLR FKESLKSDDG FNSYALYAYD SVWLVARALD
360 370 380 390 400
VFFSQGNTVT FSNDPSLRNT NDSGIKLSKL HIFNEGERFL QVILEMNYTG
410 420 430 440 450
LTGQIEFNSE KNRINPAYDI LNIKSTGPLR VGYWSNHTGF SVAPPETLYS
460 470 480 490 500
KPSNTSAKDQ RLNEIIWPGE VIKPPRGWVF PENGKPLKIG VPNRVSYKNY
510 520 530 540 550
ASKDKNPLGV KGFCIDIFEA AIQLLPYPVP RTYILYGDGK KNPSYDNLIS
560 570 580 590 600
EVAANIFDVA VGDVTIITNR TKFVDFTQPF IESGLVVVAP VKGAKSSPWS
610 620 630 640 650
FLKPFTIEMW AVTGALFLFV GAVIWILEHR FNEEFRGPPR RQIITVFWFS
660 670 680 690 700
FSTMFFSHRE NTVSTLGRFV LLVWLFVVLI INSSYTASLT SILTVQQLTS
710 720 730 740 750
RIEGMDTLIA SNEPIGVQDG TFAWKFLVNE LNIAPSRIIP LKDEEEYLSA
760 770 780 790 800
LQRGPRGGGV AAIVDELPYI KALLSNSNCK FRTVGQEFTR TGWGFAFQRD
810 820 830 840 850
SPLAVDMSTA ILQLAEEGKL EKIRKKWLTY DHECTMQISD TENYQISVQS
860 870 880 890 900
FWGLFLICGV VWFIALTLFC WKVFWQYQRL RPEESDEVQA RSEEAGSSRG
910 920 930 940 950
KSLRAVSFKD LIKVVDKREA EIKEMLKEKS SKKLKDGQSS AENSQSKDHE
TPQ
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF4ITQ0 | F4ITQ0_ARATH | Glutamate receptor 3.5 | GLR3.5 ATGLR3.5, GLR6, glutamate receptor 3.5, At2g32390, T32F6.9 | 695 | Annotation score: | ||
F4ITQ2 | F4ITQ2_ARATH | Glutamate receptor | GLR3.5 ATGLR3.5, GLR6, glutamate receptor 3.5, At2g32390, T32F6.9 | 851 | Annotation score: | ||
A0A1P8AYR0 | A0A1P8AYR0_ARATH | Glutamate receptor 3.5 | GLR3.5 ATGLR3.5, GLR6, glutamate receptor 3.5, At2g32390, T32F6.9 | 654 | Annotation score: | ||
A0A1P8AYW8 | A0A1P8AYW8_ARATH | Glutamate receptor 3.5 | GLR3.5 ATGLR3.5, GLR6, glutamate receptor 3.5, At2g32390, T32F6.9 | 668 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 78 | D → G in AAD50976 (PubMed:11379626).Curated | 1 | |
Sequence conflicti | 104 – 107 | GALQ → E in AAD50976 (PubMed:11379626).Curated | 4 | |
Sequence conflicti | 127 | I → V in AAD50976 (PubMed:11379626).Curated | 1 | |
Sequence conflicti | 159 | R → C in AAD50976 (PubMed:11379626).Curated | 1 | |
Sequence conflicti | 443 | A → V in AAD50976 (PubMed:11379626).Curated | 1 | |
Sequence conflicti | 459 | D → N in AAD50976 (PubMed:11379626).Curated | 1 | |
Sequence conflicti | 495 | V → I in AAD50976 (PubMed:11379626).Curated | 1 | |
Sequence conflicti | 550 | S → G in AAD50976 (PubMed:11379626).Curated | 1 | |
Sequence conflicti | 860 | V → A in AAD50976 (PubMed:11379626).Curated | 1 | |
Sequence conflicti | 878 | Q → H in AAD50976 (PubMed:11379626).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF170494 mRNA Translation: AAD50976.1 AC005700 Genomic DNA Translation: AAC69939.2 Sequence problems. CP002685 Genomic DNA Translation: AEC08676.1 Sequence problems. CP002685 Genomic DNA Translation: ANM61816.1 |
PIRi | E84732 T51134 |
RefSeqi | NP_001324013.1, NM_001336391.1 [Q9SW97-1] NP_565743.1, NM_128798.1 |
Genome annotation databases
EnsemblPlantsi | AT2G32390.5; AT2G32390.5; AT2G32390 [Q9SW97-1] |
GeneIDi | 817800 |
Gramenei | AT2G32390.5; AT2G32390.5; AT2G32390 [Q9SW97-1] |
KEGGi | ath:AT2G32390 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF170494 mRNA Translation: AAD50976.1 AC005700 Genomic DNA Translation: AAC69939.2 Sequence problems. CP002685 Genomic DNA Translation: AEC08676.1 Sequence problems. CP002685 Genomic DNA Translation: ANM61816.1 |
PIRi | E84732 T51134 |
RefSeqi | NP_001324013.1, NM_001336391.1 [Q9SW97-1] NP_565743.1, NM_128798.1 |
3D structure databases
AlphaFoldDBi | Q9SW97 |
SMRi | Q9SW97 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT2G32390.3 |
Proteomic databases
PRIDEi | Q9SW97 |
ProteomicsDBi | 247365 [Q9SW97-1] |
Genome annotation databases
EnsemblPlantsi | AT2G32390.5; AT2G32390.5; AT2G32390 [Q9SW97-1] |
GeneIDi | 817800 |
Gramenei | AT2G32390.5; AT2G32390.5; AT2G32390 [Q9SW97-1] |
KEGGi | ath:AT2G32390 |
Organism-specific databases
Araporti | AT2G32390 |
Phylogenomic databases
InParanoidi | Q9SW97 |
OMAi | YHCNFRI |
OrthoDBi | 188544at2759 |
PhylomeDBi | Q9SW97 |
Miscellaneous databases
PROi | PR:Q9SW97 |
Gene expression databases
ExpressionAtlasi | Q9SW97, baseline and differential |
Family and domain databases
CDDi | cd19990, PBP1_GABAb_receptor_plant, 1 hit |
InterProi | View protein in InterPro IPR001828, ANF_lig-bd_rcpt IPR044440, GABAb_receptor_plant_PBP1 IPR001320, Iontro_rcpt IPR017103, Iontropic_Glu_rcpt_pln IPR028082, Peripla_BP_I IPR001638, Solute-binding_3/MltF_N |
Pfami | View protein in Pfam PF01094, ANF_receptor, 1 hit PF00060, Lig_chan, 1 hit PF00497, SBP_bac_3, 1 hit |
PIRSFi | PIRSF037090, Iontro_Glu-like_rcpt_pln, 1 hit |
SMARTi | View protein in SMART SM00079, PBPe, 1 hit |
SUPFAMi | SSF53822, SSF53822, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GLR35_ARATH | |
Accessioni | Q9SW97Primary (citable) accession number: Q9SW97 Secondary accession number(s): F4ITQ1, Q9ZV67 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 16, 2004 |
Last sequence update: | January 16, 2004 | |
Last modified: | May 25, 2022 | |
This is version 136 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families