UniProtKB - Q9SVG4 (RETOL_ARATH)
Protein
Berberine bridge enzyme-like 19
Gene
At4g20830
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Cofactori
FADBy similarityNote: Binds 1 FAD per subunit in a bicovalent manner.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 120 | FAD (covalent; via 2 links, pros nitrogen)By similarity | 1 | |
Binding sitei | 182 | FAD (covalent; via 2 links)By similarity | 1 |
GO - Molecular functioni
- FAD binding Source: InterPro
- oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor Source: TAIR
GO - Biological processi
- defense response to fungus Source: TAIR
- response to oxidative stress Source: TAIR
Keywordsi
Molecular function | Oxidoreductase |
Ligand | FAD, Flavoprotein, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | ARA:AT4G20830-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:At4g20830 ORF Names:F21C20.180 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G20830 |
TAIRi | locus:2121539 AT4G20830 |
Subcellular locationi
Cell Wall
- plant-type cell wall Source: TAIR
Cytosol
- cytosol Source: TAIR
Extracellular region or secreted
- apoplast Source: TAIR
Mitochondrion
- mitochondrion Source: TAIR
Plasma Membrane
- plasma membrane Source: TAIR
Vacuole
- vacuole Source: TAIR
Other locations
- plasmodesma Source: TAIR
Keywords - Cellular componenti
Cell wall, SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 30 | Sequence analysisAdd BLAST | 30 | |
ChainiPRO_0000259448 | 31 – 570 | Berberine bridge enzyme-like 19Add BLAST | 540 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 42 ↔ 105 | By similarity | ||
Glycosylationi | 80 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 341 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 359 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 |
Post-translational modificationi
The FAD cofactor is bound via a bicovalent 6-S-cysteinyl, 8alpha-N1-histidyl FAD linkage.By similarity
Keywords - PTMi
Disulfide bond, GlycoproteinProteomic databases
PaxDbi | Q9SVG4 |
PRIDEi | Q9SVG4 |
PTM databases
SwissPalmi | Q9SVG4 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9SVG4 baseline and differential |
Genevisiblei | Q9SVG4 AT |
Interactioni
Protein-protein interaction databases
BioGridi | 13122, 1 interactor |
STRINGi | 3702.AT4G20830.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 83 – 257 | FAD-binding PCMH-typePROSITE-ProRule annotationAdd BLAST | 175 |
Sequence similaritiesi
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | ENOG410IKGW Eukaryota COG0277 LUCA |
HOGENOMi | HOG000238933 |
InParanoidi | Q9SVG4 |
OMAi | GYPFPGG |
OrthoDBi | 1049549at2759 |
PhylomeDBi | Q9SVG4 |
Family and domain databases
Gene3Di | 3.30.43.10, 1 hit |
InterProi | View protein in InterPro IPR012951 BBE IPR016166 FAD-bd_PCMH IPR036318 FAD-bd_PCMH-like_sf IPR016167 FAD-bd_PCMH_sub1 IPR006094 Oxid_FAD_bind_N |
Pfami | View protein in Pfam PF08031 BBE, 1 hit PF01565 FAD_binding_4, 1 hit |
SUPFAMi | SSF56176 SSF56176, 1 hit |
PROSITEi | View protein in PROSITE PS51387 FAD_PCMH, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q9SVG4-1) [UniParc]FASTAAdd to basket
Also known as: AtBBE-like 19
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MLTTPPRTFV SVPFFFFFLL FLSLPLSSFS QSNSVYNSFL KCFSDKTKSP
60 70 80 90 100
QSQITDNVFS QTNPAFSSVL RAYIRNARFN TSSTLKPTII ITPRSESHVS
110 120 130 140 150
AAVTCSKTLN FLLKIRSGGH DYDGLSYISD KPFFILDMSN IRDVSVDIAS
160 170 180 190 200
NSAWISAGAT LGEVYYRIWE KSRVHGFPAG VCPTVGVGGH LSGGGYGNMV
210 220 230 240 250
RKFGLSVDYV EDAKIVDVNG RVLDRKAMGE DLFWAITGGG GGSYGVVLGY
260 270 280 290 300
KVKLVPVPSV VTVFRVEQYM DSGAVDMVHK WQSVGPKTDP NLFMRMLIQP
310 320 330 340 350
VTRKKVKTVR ASVVALFLGR ADEVVALLSK EFPELGLKKE NCSEMTWFQS
360 370 380 390 400
ALWWDNRLNA TQVDPKVFLD RNLDTSSFGK RKSDYVATAI PKKGIESLFK
410 420 430 440 450
KMIELGKIGL VFNPYGGKMA EVAVNAKPFP HRNKLFKIQY SVNWKENSAE
460 470 480 490 500
IEKGYLNQAK VLYSFMTGFV SKNPRSSYFN YRDVDIGVND HGANSYKEGE
510 520 530 540 550
VYGRKYFGEN FDRLVKIKTA VDPGNFFRNE QSIPTLKNEK GMLLPEPGKA
560 570
RRWSRVGGAT VVATVVLHVF
Note: Derived from EST data. No experimental confirmation available.
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 14 | Missing in AAN60314 (Ref. 5) Curated | 1 | |
Sequence conflicti | 45 | D → E in AAN60314 (Ref. 5) Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_021389 | 538 – 540 | NEK → SKA in isoform 2. 1 Publication | 3 | |
Alternative sequenceiVSP_021390 | 541 – 570 | Missing in isoform 2. 1 PublicationAdd BLAST | 30 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL080254 Genomic DNA Translation: CAB45849.1 AL161553 Genomic DNA Translation: CAB79083.1 CP002687 Genomic DNA Translation: AEE84365.1 CP002687 Genomic DNA Translation: AEE84366.1 AY133533 mRNA Translation: AAM91363.1 AY062595 mRNA Translation: AAL32673.1 AF424621 mRNA Translation: AAL11614.1 AK316833 mRNA Translation: BAH19545.1 AF083756 mRNA Translation: AAN60314.1 |
PIRi | T10625 |
RefSeqi | NP_193815.2, NM_118201.3 [Q9SVG4-1] NP_974580.1, NM_202851.1 [Q9SVG4-2] |
Genome annotation databases
EnsemblPlantsi | AT4G20830.1; AT4G20830.1; AT4G20830 [Q9SVG4-1] AT4G20830.2; AT4G20830.2; AT4G20830 [Q9SVG4-2] |
GeneIDi | 827831 |
Gramenei | AT4G20830.1; AT4G20830.1; AT4G20830 [Q9SVG4-1] AT4G20830.2; AT4G20830.2; AT4G20830 [Q9SVG4-2] |
KEGGi | ath:AT4G20830 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL080254 Genomic DNA Translation: CAB45849.1 AL161553 Genomic DNA Translation: CAB79083.1 CP002687 Genomic DNA Translation: AEE84365.1 CP002687 Genomic DNA Translation: AEE84366.1 AY133533 mRNA Translation: AAM91363.1 AY062595 mRNA Translation: AAL32673.1 AF424621 mRNA Translation: AAL11614.1 AK316833 mRNA Translation: BAH19545.1 AF083756 mRNA Translation: AAN60314.1 |
PIRi | T10625 |
RefSeqi | NP_193815.2, NM_118201.3 [Q9SVG4-1] NP_974580.1, NM_202851.1 [Q9SVG4-2] |
3D structure databases
SMRi | Q9SVG4 |
ModBasei | Search... |
Protein-protein interaction databases
BioGridi | 13122, 1 interactor |
STRINGi | 3702.AT4G20830.1 |
PTM databases
SwissPalmi | Q9SVG4 |
Proteomic databases
PaxDbi | Q9SVG4 |
PRIDEi | Q9SVG4 |
Genome annotation databases
EnsemblPlantsi | AT4G20830.1; AT4G20830.1; AT4G20830 [Q9SVG4-1] AT4G20830.2; AT4G20830.2; AT4G20830 [Q9SVG4-2] |
GeneIDi | 827831 |
Gramenei | AT4G20830.1; AT4G20830.1; AT4G20830 [Q9SVG4-1] AT4G20830.2; AT4G20830.2; AT4G20830 [Q9SVG4-2] |
KEGGi | ath:AT4G20830 |
Organism-specific databases
Araporti | AT4G20830 |
TAIRi | locus:2121539 AT4G20830 |
Phylogenomic databases
eggNOGi | ENOG410IKGW Eukaryota COG0277 LUCA |
HOGENOMi | HOG000238933 |
InParanoidi | Q9SVG4 |
OMAi | GYPFPGG |
OrthoDBi | 1049549at2759 |
PhylomeDBi | Q9SVG4 |
Enzyme and pathway databases
BioCyci | ARA:AT4G20830-MONOMER |
Miscellaneous databases
PROi | PR:Q9SVG4 |
Gene expression databases
ExpressionAtlasi | Q9SVG4 baseline and differential |
Genevisiblei | Q9SVG4 AT |
Family and domain databases
Gene3Di | 3.30.43.10, 1 hit |
InterProi | View protein in InterPro IPR012951 BBE IPR016166 FAD-bd_PCMH IPR036318 FAD-bd_PCMH-like_sf IPR016167 FAD-bd_PCMH_sub1 IPR006094 Oxid_FAD_bind_N |
Pfami | View protein in Pfam PF08031 BBE, 1 hit PF01565 FAD_binding_4, 1 hit |
SUPFAMi | SSF56176 SSF56176, 1 hit |
PROSITEi | View protein in PROSITE PS51387 FAD_PCMH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RETOL_ARATH | |
Accessioni | Q9SVG4Primary (citable) accession number: Q9SVG4 Secondary accession number(s): B9DFM8, Q3E9Y2, Q8H7B5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2006 |
Last sequence update: | October 31, 2006 | |
Last modified: | October 16, 2019 | |
This is version 125 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names