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Entry version 95 (31 Jul 2019)
Sequence version 1 (01 May 2000)
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Protein
Submitted name:

Uncharacterized protein AT4g38350

Gene

F22I13.120

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein AT4g38350Imported
Submitted name:
Uncharacterized protein F22I13.120Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:F22I13.120Imported
Ordered Locus Names:At4g38350Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei222 – 241HelicalSequence analysisAdd BLAST20
Transmembranei309 – 328HelicalSequence analysisAdd BLAST20
Transmembranei578 – 602HelicalSequence analysisAdd BLAST25
Transmembranei608 – 633HelicalSequence analysisAdd BLAST26
Transmembranei653 – 675HelicalSequence analysisAdd BLAST23
Transmembranei681 – 707HelicalSequence analysisAdd BLAST27
Transmembranei754 – 776HelicalSequence analysisAdd BLAST23
Transmembranei911 – 929HelicalSequence analysisAdd BLAST19
Transmembranei936 – 958HelicalSequence analysisAdd BLAST23
Transmembranei978 – 997HelicalSequence analysisAdd BLAST20
Transmembranei1009 – 1029HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9SVF0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SVF0 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini544 – 707SSDInterPro annotationAdd BLAST164

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032190 NPC1_N
IPR003392 Ptc/Disp
IPR000731 SSD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16414 NPC1_N, 1 hit
PF02460 Patched, 1 hit
PF12349 Sterol-sensing, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50156 SSD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9SVF0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYDICGHRSD GKVLNCPYAS PSIQPDELFS AKIQSLCPTI SGNVCCTETQ
60 70 80 90 100
FDTLRSQVQQ AVPFLVGCPA CLRNFLNLFC ELSCSPNQSL FINVTSVAEV
110 120 130 140 150
SGNLTVDGID YHITDTFGEG LYESCKEVKF GTMNTRAINF VGGGAKNFRE
160 170 180 190 200
WFTFIGQKAP SGFPGSPYAI NFKSSIPESS AMVPMNVSVY SCACSSPEPL
210 220 230 240 250
PPHDEDSCSI RIGPLKVRCI ELSMALVYVL LVSCFFGWAG LNRRRNTTQP
260 270 280 290 300
LDSSKPLLHP VEEDGINSEM KENILGVKVQ RHAQLSPVQR YMAKFYRSYG
310 320 330 340 350
SWIARNPSLV LFMSVAIVLA LCSGLYNFKV ETRPEKLWVG PESKAAEEKK
360 370 380 390 400
FFDTHLSPFY RIEQLILATV PDPKSGRAPS IVTDENILLL FDIQQKYFKM
410 420 430 440 450
DSGTFDDYGG VEHAEYCFQH YTSSETCLSA FQAPVDPSAV LGGFSGNNYS
460 470 480 490 500
EVMVSELGCS VPFDCYSDVK RTLFQATAFV VTYPVNNVIG DSSNENARAV
510 520 530 540 550
AWEKSFIQLA KEELLPMVRS KNLSLSFSSE SSIEEELKRE STADVITIAA
560 570 580 590 600
SYLVMFVYIS VTLGDAPQFY TFYISSKVLL GLSGVVLVLL SVLGSVGVFS
610 620 630 640 650
ALGVKSTLII MEVIPFLVLA VGVDNMCILV HAVKRQPREV SLEQRISSAL
660 670 680 690 700
VEVGPSITLA SLSEVLAFAV GAFVPMPACR IFSMFAALAI MLDFFLQITA
710 720 730 740 750
FVALIVFDCK RSADNRIDCF PCIKVPSSSR ESVEGGREPG FLERYMKEVH
760 770 780 790 800
APVLGLWGVK MVVVAVFFAF ALASIISRAS QASDTSYIAK PAASWLDDFL
810 820 830 840 850
VWLSPEAFGC CRKFTNGSYC PPDDQCFRHS DLVQDRPSTA QFREKLPWFL
860 870 880 890 900
NALPSADCAK GGHGAYTNSV DLKGYESGVI QASEFRTYHT PLNTQIDIFP
910 920 930 940 950
YSVFYIFFEQ YLNIWTVALT NLAIAIVGIQ LNAVSVVNLI MSIGIAVEFC
960 970 980 990 1000
VHISHAFLMS SGDREHRARE ALETMGASVF SGITLTKLVG VIVLCFARSE
1010 1020 1030 1040 1050
IFVVYYFQMY LALVIIGFLH GLVFLPVILS LAGPPQLNLD IEQQQTDEAS

SSLLN
Length:1,055
Mass (Da):116,149
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i15E154A61DC936BC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL035539 Genomic DNA Translation: CAB37491.1
AL161593 Genomic DNA Translation: CAB80500.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T05663

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035539 Genomic DNA Translation: CAB37491.1
AL161593 Genomic DNA Translation: CAB80500.1
PIRiT05663

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiQ9SVF0

Gene expression databases

ExpressionAtlasiQ9SVF0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR032190 NPC1_N
IPR003392 Ptc/Disp
IPR000731 SSD
PfamiView protein in Pfam
PF16414 NPC1_N, 1 hit
PF02460 Patched, 1 hit
PF12349 Sterol-sensing, 1 hit
PROSITEiView protein in PROSITE
PS50156 SSD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9SVF0_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SVF0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 31, 2019
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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