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UniProtKB - Q9SUM3 (NCPR2_ARATH)

Entry version 141 (07 Apr 2021)
Sequence version 1 (01 May 2000)
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Protein

NADPH--cytochrome P450 reductase 2

Gene

ATR2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and dichloroindophenol.UniRule annotation5 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=23 µM for NADPH (at pH 7.7 and 28 degrees Celsius)4 Publications
  2. KM=2.0 µM for NADPH (at pH 7.25 and 25 degrees Celsius)4 Publications
  3. KM=15 µM for cytochrome c (at pH 7.7 and 30 degrees Celsius)4 Publications
  4. KM=16 µM for cytochrome c (at pH 7.0 and 25 degrees Celsius)4 Publications
  5. KM=22.5 µM for cytochrome c (at pH 7.7 and 28 degrees Celsius)4 Publications

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei239FMNUniRule annotation1
    Binding sitei330NADPUniRule annotation1
    Binding sitei570NADPUniRule annotation1
    Binding sitei673NADPUniRule annotation1
    Binding sitei711FADUniRule annotation1

    Regions

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi111 – 116FMNUniRule annotation6
    Nucleotide bindingi166 – 169FMNUniRule annotation4
    Nucleotide bindingi204 – 213FMNUniRule annotation10
    Nucleotide bindingi489 – 492FADUniRule annotation4
    Nucleotide bindingi507 – 509FADUniRule annotation3
    Nucleotide bindingi523 – 526FADUniRule annotation4
    Nucleotide bindingi631 – 632NADPUniRule annotation2
    Nucleotide bindingi637 – 641NADPUniRule annotation5

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    Complete GO annotation on QuickGO ...

    GO - Biological processi

    Complete GO annotation on QuickGO ...

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionOxidoreductase
    Biological processPhenylpropanoid metabolism
    LigandFAD, Flavoprotein, FMN, NADP

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...    BioCyci    		MetaCyc:MONOMER-2102

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    NADPH--cytochrome P450 reductase 2UniRule annotation (EC:1.6.2.4UniRule annotation)
    Short name:
    CPR 2UniRule annotation
    Short name:
    P450R 2UniRule annotation
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:ATR2
    Synonyms:AR2
    Ordered Locus Names:At4g30210
    ORF Names:F9N11.60
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

    Organism-specific databases

    Arabidopsis Information Portal

    More...    Araporti    		AT4G30210

    The Arabidopsis Information Resource

    More...    TAIRi    		locus:2128951, AT4G30210

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 51LumenalUniRule annotationAdd BLAST51
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei52 – 72HelicalUniRule annotationAdd BLAST21
    Topological domaini73 – 711CytoplasmicUniRule annotationAdd BLAST639

    Keywords - Cellular componenti

    Endoplasmic reticulum, Membrane

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004168401 – 711NADPH--cytochrome P450 reductase 2Add BLAST711

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...    PaxDbi    		Q9SUM3

    PRoteomics IDEntifications database

    More...    PRIDEi    		Q9SUM3

    ProteomicsDB: a multi-organism proteome resource

    More...    ProteomicsDBi    		251241 [Q9SUM3-1]

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...    iPTMneti    		Q9SUM3

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed in roots, leaves, stems, flowers and siliques.1 Publication

    <p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    By wounding and transition from dark to light.1 Publication

    Gene expression databases

    ExpressionAtlas, Differential and Baseline Expression

    More...    ExpressionAtlasi    		Q9SUM3, baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...    Genevisiblei    		Q9SUM3, AT

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...    STRINGi    		3702.AT4G30210.1

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    Secondary structure

    1711
    Legend: HelixTurnBeta strandPDB Structure known for this area
    Show more details

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...    SMRi    		Q9SUM3

    Database of comparative protein structure models

    More...    ModBasei    		Search...

    Protein Data Bank in Europe - Knowledge Base

    More...    PDBe-KBi    		Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini105 – 255Flavodoxin-likeUniRule annotationAdd BLAST151
    Domaini310 – 556FAD-binding FR-typeUniRule annotationAdd BLAST247

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the NADPH--cytochrome P450 reductase family.UniRule annotation
    In the N-terminal section; belongs to the flavodoxin family.UniRule annotation
    In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...    eggNOGi    		KOG1158, Eukaryota

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...    HOGENOMi    		CLU_001570_17_3_1

    InParanoid: Eukaryotic Ortholog Groups

    More...    InParanoidi    		Q9SUM3

    Database for complete collections of gene phylogenies

    More...    PhylomeDBi    		Q9SUM3

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...    Gene3Di    		1.20.990.10, 1 hit
    3.40.50.360, 1 hit
    3.40.50.80, 1 hit

    HAMAP database of protein families

    More...    HAMAPi    		MF_03212, NCPR, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...    InterProi    		View protein in InterPro
    IPR003097, CysJ-like_FAD-binding
    IPR017927, FAD-bd_FR_type
    IPR001094, Flavdoxin-like
    IPR008254, Flavodoxin/NO_synth
    IPR001709, Flavoprot_Pyr_Nucl_cyt_Rdtase
    IPR029039, Flavoprotein-like_sf
    IPR039261, FNR_nucleotide-bd
    IPR023173, NADPH_Cyt_P450_Rdtase_alpha
    IPR001433, OxRdtase_FAD/NAD-bd
    IPR023208, P450R
    IPR017938, Riboflavin_synthase-like_b-brl

    Pfam protein domain database

    More...    Pfami    		View protein in Pfam
    PF00667, FAD_binding_1, 1 hit
    PF00258, Flavodoxin_1, 1 hit
    PF00175, NAD_binding_1, 1 hit

    PIRSF; a whole-protein classification database

    More...    PIRSFi    		PIRSF000208, P450R, 1 hit

    Protein Motif fingerprint database; a protein domain database

    More...    PRINTSi    		PR00369, FLAVODOXIN
    PR00371, FPNCR

    Superfamily database of structural and functional annotation

    More...    SUPFAMi    		SSF52218, SSF52218, 1 hit
    SSF52343, SSF52343, 1 hit
    SSF63380, SSF63380, 1 hit

    PROSITE; a protein domain and family database

    More...    PROSITEi    		View protein in PROSITE
    PS51384, FAD_FR, 1 hit
    PS50902, FLAVODOXIN_LIKE, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

    This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

    Isoform 1 (identifier: Q9SUM3-1) [UniParc]FASTAAdd to basket

    This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide
            10         20         30         40         50
    MSSSSSSSTS MIDLMAAIIK GEPVIVSDPA NASAYESVAA ELSSMLIENR 
            60         70         80         90        100
    QFAMIVTTSI AVLIGCIVML VWRRSGSGNS KRVEPLKPLV IKPREEEIDD 
           110        120        130        140        150
    GRKKVTIFFG TQTGTAEGFA KALGEEAKAR YEKTRFKIVD LDDYAADDDE 
           160        170        180        190        200
    YEEKLKKEDV AFFFLATYGD GEPTDNAARF YKWFTEGNDR GEWLKNLKYG 
           210        220        230        240        250
    VFGLGNRQYE HFNKVAKVVD DILVEQGAQR LVQVGLGDDD QCIEDDFTAW 
           260        270        280        290        300
    REALWPELDT ILREEGDTAV ATPYTAAVLE YRVSIHDSED AKFNDINMAN 
           310        320        330        340        350
    GNGYTVFDAQ HPYKANVAVK RELHTPESDR SCIHLEFDIA GSGLTYETGD 
           360        370        380        390        400
    HVGVLCDNLS ETVDEALRLL DMSPDTYFSL HAEKEDGTPI SSSLPPPFPP 
           410        420        430        440        450
    CNLRTALTRY ACLLSSPKKS ALVALAAHAS DPTEAERLKH LASPAGKDEY 
           460        470        480        490        500
    SKWVVESQRS LLEVMAEFPS AKPPLGVFFA GVAPRLQPRF YSISSSPKIA 
           510        520        530        540        550
    ETRIHVTCAL VYEKMPTGRI HKGVCSTWMK NAVPYEKSEN CSSAPIFVRQ 
           560        570        580        590        600
    SNFKLPSDSK VPIIMIGPGT GLAPFRGFLQ ERLALVESGV ELGPSVLFFG 
           610        620        630        640        650
    CRNRRMDFIY EEELQRFVES GALAELSVAF SREGPTKEYV QHKMMDKASD 
           660        670        680        690        700
    IWNMISQGAY LYVCGDAKGM ARDVHRSLHT IAQEQGSMDS TKAEGFVKNL 
           710 
    QTSGRYLRDV W
    Length:711
    Mass (Da):78,927
    Last modified:May 1, 2000 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF0503108EB7F508F
    GO
    Isoform 2 (identifier: Q9SUM3-2) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         447-447: K → KV

    Note: May be due to a competing donor splice site.Curated
    Show »
    Length:712
    Mass (Da):79,026
    Checksum:i75656CFE0CC4DB63
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    		Gene namesLengthAnnotation
    A0A1P8B3S1A0A1P8B3S1_ARATH
    NADPH--cytochrome P450 reductase
    ATR2 AR2, P450 reductase 2, At4g30210, F9N11.60, F9N11_60
    		774Annotation score:

    Annotation score:3 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti297 – 298NM → TL in CAA46815 (PubMed:9235908).Curated2
    Sequence conflicti346 – 348YET → MKL in CAA46815 (PubMed:9235908).Curated3
    Sequence conflicti540 – 544NCSSA → KLFLGR in CAA46815 (PubMed:9235908).Curated5

    Alternative sequence

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_042906447K → KV in isoform 2. Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...    EMBLi

    GenBank nucleotide sequence database

    More...    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...    DDBJi
    Links Updated
    		X66017 mRNA Translation: CAA46815.1
    AL109796 Genomic DNA Translation: CAB52465.1
    AL161576 Genomic DNA Translation: CAB81014.1
    CP002687 Genomic DNA Translation: AEE85737.1
    CP002687 Genomic DNA Translation: AEE85738.1
    AF325101 mRNA Translation: AAK17169.1

    Protein sequence database of the Protein Information Resource

    More...    PIRi    		S21531
    T14081

    NCBI Reference Sequences

    More...    RefSeqi    		NP_194750.1, NM_119167.4 [Q9SUM3-1]
    NP_849472.2, NM_179141.2 [Q9SUM3-2]

    Genome annotation databases

    Ensembl plant genome annotation project

    More...    EnsemblPlantsi    		AT4G30210.1; AT4G30210.1; AT4G30210 [Q9SUM3-2]
    AT4G30210.2; AT4G30210.2; AT4G30210 [Q9SUM3-1]

    Database of genes from NCBI RefSeq genomes

    More...    GeneIDi    		829144

    Gramene; a comparative resource for plants

    More...    Gramenei    		AT4G30210.1; AT4G30210.1; AT4G30210 [Q9SUM3-2]
    AT4G30210.2; AT4G30210.2; AT4G30210 [Q9SUM3-1]

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...    KEGGi    		ath:AT4G30210

    Keywords - Coding sequence diversityi

    Alternative splicing

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    		X66017 mRNA Translation: CAA46815.1
    AL109796 Genomic DNA Translation: CAB52465.1
    AL161576 Genomic DNA Translation: CAB81014.1
    CP002687 Genomic DNA Translation: AEE85737.1
    CP002687 Genomic DNA Translation: AEE85738.1
    AF325101 mRNA Translation: AAK17169.1
    PIRiS21531
    T14081
    RefSeqiNP_194750.1, NM_119167.4 [Q9SUM3-1]
    NP_849472.2, NM_179141.2 [Q9SUM3-2]

    3D structure databases

    Select the link destinations:

    Protein Data Bank Europe

    More...    PDBei

    Protein Data Bank RCSB

    More...    RCSB PDBi

    Protein Data Bank Japan

    More...    PDBji
    Links Updated
    		PDB entryMethodResolution (Å)ChainPositionsPDBsum
    5GXUX-ray2.30A/B73-711[»]
    SMRiQ9SUM3
    ModBaseiSearch...
    PDBe-KBiSearch...

    Protein-protein interaction databases

    STRINGi3702.AT4G30210.1

    PTM databases

    iPTMnetiQ9SUM3

    Proteomic databases

    PaxDbiQ9SUM3
    PRIDEiQ9SUM3
    ProteomicsDBi251241 [Q9SUM3-1]

    Genome annotation databases

    EnsemblPlantsiAT4G30210.1; AT4G30210.1; AT4G30210 [Q9SUM3-2]
    AT4G30210.2; AT4G30210.2; AT4G30210 [Q9SUM3-1]
    GeneIDi829144
    GrameneiAT4G30210.1; AT4G30210.1; AT4G30210 [Q9SUM3-2]
    AT4G30210.2; AT4G30210.2; AT4G30210 [Q9SUM3-1]
    KEGGiath:AT4G30210

    Organism-specific databases

    AraportiAT4G30210
    TAIRilocus:2128951, AT4G30210

    Phylogenomic databases

    eggNOGiKOG1158, Eukaryota
    HOGENOMiCLU_001570_17_3_1
    InParanoidiQ9SUM3
    PhylomeDBiQ9SUM3

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-2102

    Miscellaneous databases

    Protein Ontology

    More...    PROi    		PR:Q9SUM3

    Gene expression databases

    ExpressionAtlasiQ9SUM3, baseline and differential
    GenevisibleiQ9SUM3, AT

    Family and domain databases

    Gene3Di1.20.990.10, 1 hit
    3.40.50.360, 1 hit
    3.40.50.80, 1 hit
    HAMAPiMF_03212, NCPR, 1 hit
    InterProiView protein in InterPro
    IPR003097, CysJ-like_FAD-binding
    IPR017927, FAD-bd_FR_type
    IPR001094, Flavdoxin-like
    IPR008254, Flavodoxin/NO_synth
    IPR001709, Flavoprot_Pyr_Nucl_cyt_Rdtase
    IPR029039, Flavoprotein-like_sf
    IPR039261, FNR_nucleotide-bd
    IPR023173, NADPH_Cyt_P450_Rdtase_alpha
    IPR001433, OxRdtase_FAD/NAD-bd
    IPR023208, P450R
    IPR017938, Riboflavin_synthase-like_b-brl
    PfamiView protein in Pfam
    PF00667, FAD_binding_1, 1 hit
    PF00258, Flavodoxin_1, 1 hit
    PF00175, NAD_binding_1, 1 hit
    PIRSFiPIRSF000208, P450R, 1 hit
    PRINTSiPR00369, FLAVODOXIN
    PR00371, FPNCR
    SUPFAMiSSF52218, SSF52218, 1 hit
    SSF52343, SSF52343, 1 hit
    SSF63380, SSF63380, 1 hit
    PROSITEiView protein in PROSITE
    PS51384, FAD_FR, 1 hit
    PS50902, FLAVODOXIN_LIKE, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...    ProtoNeti    		Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...    MobiDBi    		Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNCPR2_ARATH
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SUM3
    Secondary accession number(s): F4JPK2, Q39036
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2012
    Last sequence update: May 1, 2000
    Last modified: April 7, 2021
    This is version 141 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    3D-structure, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families
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