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Entry version 119 (02 Dec 2020)
Sequence version 1 (01 May 2000)
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Protein

Cullin-2

Gene

CUL2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes. Involved in ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cullin-2
Short name:
AtCUL1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CUL2
Ordered Locus Names:At1g02980
ORF Names:F22D16.2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

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Araporti
AT1G02980

The Arabidopsis Information Resource

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TAIRi
locus:2024755, AT1G02980

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003968481 – 742Cullin-2Add BLAST742

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki686Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in NEDD8)By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Neddylated; which enhances the ubiquitination activity of E3 ubiquitin-protein ligase complexes.By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9SRZ0

PRoteomics IDEntifications database

More...
PRIDEi
Q9SRZ0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
220461

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9SRZ0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SRZ0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9SRZ0, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SKIP17 and FBW2/SKIP18.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
24650, 2 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1471, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-SKP1A
CPX-1472, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-SKP1B
CPX-1473, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK3
CPX-1474, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK4
CPX-1475, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK5
CPX-1476, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK6
CPX-1477, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK7
CPX-1478, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK8
CPX-1479, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK9
CPX-1480, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK10
CPX-1481, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK11
CPX-1482, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK12
CPX-1483, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK13
CPX-1484, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK14
CPX-1485, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK15
CPX-1486, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK16
CPX-1487, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK17
CPX-1488, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK18
CPX-1489, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK19
CPX-1490, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK20
CPX-1491, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK21
CPX-1492, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-SKP1A
CPX-1493, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-SKP1B
CPX-1494, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK3
CPX-1495, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK4
CPX-1496, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK5
CPX-1497, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK6
CPX-1498, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK7
CPX-1499, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK8
CPX-1502, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK9
CPX-1503, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK10
CPX-1504, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK11
CPX-1505, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK12
CPX-1506, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK13
CPX-1507, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK14
CPX-1508, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK15
CPX-1509, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK16
CPX-1510, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK17
CPX-1511, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK18
CPX-1512, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK19
CPX-1513, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK20
CPX-1514, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK21
CPX-1557, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-SKP1A
CPX-1558, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-SKP1B
CPX-1559, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK3
CPX-1560, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK4
CPX-1561, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK5
CPX-1562, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK6
CPX-1563, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK7
CPX-1564, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK8
CPX-1565, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK9
CPX-1566, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK10
CPX-1567, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK11
CPX-1568, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK12
CPX-1569, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK13
CPX-1570, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK14
CPX-1571, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK15
CPX-1572, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK16
CPX-1573, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK17
CPX-1574, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK18
CPX-1575, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK19
CPX-1576, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK20
CPX-1577, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK21
CPX-1578, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-SKP1A
CPX-1579, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-SKP1B
CPX-1580, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK3
CPX-1581, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK4
CPX-1582, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK5
CPX-1583, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK6
CPX-1584, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK7
CPX-1585, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK8
CPX-1586, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK9
CPX-1587, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK10
CPX-1588, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK11
CPX-1589, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK12
CPX-1590, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK13
CPX-1591, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK14
CPX-1592, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK15
CPX-1593, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK16
CPX-1594, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK17
CPX-1595, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK18
CPX-1596, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK19
CPX-1597, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK20
CPX-1598, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK21

STRING: functional protein association networks

More...
STRINGi
3702.AT1G02980.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9SRZ0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the cullin family.PROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2166, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004747_3_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9SRZ0

Database of Orthologous Groups

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OrthoDBi
1040292at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9SRZ0

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016158, Cullin_homology
IPR036317, Cullin_homology_sf
IPR001373, Cullin_N
IPR019559, Cullin_neddylation_domain
IPR016159, Cullin_repeat-like_dom_sf
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00888, Cullin, 1 hit
PF10557, Cullin_Nedd8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00182, CULLIN, 1 hit
SM00884, Cullin_Nedd8, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 1 hit
SSF74788, SSF74788, 1 hit
SSF75632, SSF75632, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50069, CULLIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9SRZ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKKDSVLEA GWSVMEAGVA KLQKILEEVP DEPPFDPVQR MQLYTTVHNL
60 70 80 90 100
CTQKPPNDYS QQIYDRYGGV YVDYNKQTVL PAIREKHGEY MLRELVKRWA
110 120 130 140 150
NQKILVRWLS HFFEYLDRFY TRRGSHPTLS AVGFISFRDL VYQELQSKAK
160 170 180 190 200
DAVLALIHKE REGEQIDRAL LKNVIDVYCG NGMGELVKYE EDFESFLLED
210 220 230 240 250
SASYYSRNAS RWNQENSCPD YMIKAEESLR LEKERVTNYL HSTTEPKLVA
260 270 280 290 300
KVQNELLVVV AKQLIENEHS GCRALLRDDK MDDLARMYRL YHPIPQGLDP
310 320 330 340 350
VADLFKQHIT VEGSALIKQA TEAATDKAAS TSGLKVQDQV LIRQLIDLHD
360 370 380 390 400
KFMVYVDECF QKHSLFHKAL KEAFEVFCNK TVAGVSSAEI LATYCDNILK
410 420 430 440 450
TGGGIEKLEN EDLELTLEKV VKLLVYISDK DLFAEFFRKK QARRLLFDRN
460 470 480 490 500
GNDYHERSLL TKFKELLGAQ FTSKMEGMLT DMTLAKEHQT NFVEFLSVNK
510 520 530 540 550
TKKLGMDFTV TVLTTGFWPS YKTTDLNLPI EMVNCVEAFK AYYGTKTNSR
560 570 580 590 600
RLSWIYSLGT CQLAGKFDKK TIEIVVTTYQ AAVLLLFNNT ERLSYTEILE
610 620 630 640 650
QLNLGHEDLA RLLHSLSCLK YKILIKEPMS RNISNTDTFE FNSKFTDKMR
660 670 680 690 700
RIRVPLPPMD ERKKIVEDVD KDRRYAIDAA LVRIMKSRKV LGHQQLVSEC
710 720 730 740
VEHLSKMFKP DIKMIKKRIE DLISRDYLER DTDNPNTFKY LA
Length:742
Mass (Da):85,965
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i453EF10CDA6A82F8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC009525 Genomic DNA Translation: AAF02868.1
CP002684 Genomic DNA Translation: AEE27509.1
CP002684 Genomic DNA Translation: ANM59352.1
AK117909 mRNA Translation: BAC42547.1
BT006231 mRNA Translation: AAP12880.1

Protein sequence database of the Protein Information Resource

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PIRi
D86160

NCBI Reference Sequences

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RefSeqi
NP_001318910.1, NM_001331372.1
NP_171797.2, NM_100179.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G02980.1; AT1G02980.1; AT1G02980
AT1G02980.2; AT1G02980.2; AT1G02980

Database of genes from NCBI RefSeq genomes

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GeneIDi
839415

Gramene; a comparative resource for plants

More...
Gramenei
AT1G02980.1; AT1G02980.1; AT1G02980
AT1G02980.2; AT1G02980.2; AT1G02980

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G02980

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009525 Genomic DNA Translation: AAF02868.1
CP002684 Genomic DNA Translation: AEE27509.1
CP002684 Genomic DNA Translation: ANM59352.1
AK117909 mRNA Translation: BAC42547.1
BT006231 mRNA Translation: AAP12880.1
PIRiD86160
RefSeqiNP_001318910.1, NM_001331372.1
NP_171797.2, NM_100179.4

3D structure databases

SMRiQ9SRZ0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi24650, 2 interactors
ComplexPortaliCPX-1471, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-SKP1A
CPX-1472, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-SKP1B
CPX-1473, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK3
CPX-1474, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK4
CPX-1475, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK5
CPX-1476, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK6
CPX-1477, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK7
CPX-1478, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK8
CPX-1479, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK9
CPX-1480, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK10
CPX-1481, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK11
CPX-1482, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK12
CPX-1483, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK13
CPX-1484, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK14
CPX-1485, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK15
CPX-1486, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK16
CPX-1487, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK17
CPX-1488, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK18
CPX-1489, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK19
CPX-1490, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK20
CPX-1491, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK21
CPX-1492, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-SKP1A
CPX-1493, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-SKP1B
CPX-1494, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK3
CPX-1495, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK4
CPX-1496, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK5
CPX-1497, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK6
CPX-1498, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK7
CPX-1499, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK8
CPX-1502, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK9
CPX-1503, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK10
CPX-1504, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK11
CPX-1505, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK12
CPX-1506, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK13
CPX-1507, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK14
CPX-1508, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK15
CPX-1509, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK16
CPX-1510, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK17
CPX-1511, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK18
CPX-1512, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK19
CPX-1513, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK20
CPX-1514, SCF(COI1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK21
CPX-1557, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-SKP1A
CPX-1558, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-SKP1B
CPX-1559, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK3
CPX-1560, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK4
CPX-1561, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK5
CPX-1562, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK6
CPX-1563, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK7
CPX-1564, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK8
CPX-1565, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK9
CPX-1566, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK10
CPX-1567, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK11
CPX-1568, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK12
CPX-1569, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK13
CPX-1570, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK14
CPX-1571, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK15
CPX-1572, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK16
CPX-1573, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK17
CPX-1574, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK18
CPX-1575, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK19
CPX-1576, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK20
CPX-1577, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1A-ASK21
CPX-1578, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-SKP1A
CPX-1579, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-SKP1B
CPX-1580, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK3
CPX-1581, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK4
CPX-1582, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK5
CPX-1583, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK6
CPX-1584, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK7
CPX-1585, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK8
CPX-1586, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK9
CPX-1587, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK10
CPX-1588, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK11
CPX-1589, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK12
CPX-1590, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK13
CPX-1591, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK14
CPX-1592, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK15
CPX-1593, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK16
CPX-1594, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK17
CPX-1595, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK18
CPX-1596, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK19
CPX-1597, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK20
CPX-1598, SCF(TIR1) ubiquitin ligase complex, variant CUL2-RBX1B-ASK21
STRINGi3702.AT1G02980.1

PTM databases

iPTMnetiQ9SRZ0

Proteomic databases

PaxDbiQ9SRZ0
PRIDEiQ9SRZ0
ProteomicsDBi220461

Genome annotation databases

EnsemblPlantsiAT1G02980.1; AT1G02980.1; AT1G02980
AT1G02980.2; AT1G02980.2; AT1G02980
GeneIDi839415
GrameneiAT1G02980.1; AT1G02980.1; AT1G02980
AT1G02980.2; AT1G02980.2; AT1G02980
KEGGiath:AT1G02980

Organism-specific databases

AraportiAT1G02980
TAIRilocus:2024755, AT1G02980

Phylogenomic databases

eggNOGiKOG2166, Eukaryota
HOGENOMiCLU_004747_3_0_1
InParanoidiQ9SRZ0
OrthoDBi1040292at2759
PhylomeDBiQ9SRZ0

Miscellaneous databases

Protein Ontology

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PROi
PR:Q9SRZ0

Gene expression databases

ExpressionAtlasiQ9SRZ0, baseline and differential
GenevisibleiQ9SRZ0, AT

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR016158, Cullin_homology
IPR036317, Cullin_homology_sf
IPR001373, Cullin_N
IPR019559, Cullin_neddylation_domain
IPR016159, Cullin_repeat-like_dom_sf
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF00888, Cullin, 1 hit
PF10557, Cullin_Nedd8, 1 hit
SMARTiView protein in SMART
SM00182, CULLIN, 1 hit
SM00884, Cullin_Nedd8, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
SSF74788, SSF74788, 1 hit
SSF75632, SSF75632, 1 hit
PROSITEiView protein in PROSITE
PS50069, CULLIN_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCUL2_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SRZ0
Secondary accession number(s): Q8GY26
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: May 1, 2000
Last modified: December 2, 2020
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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