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Entry version 124 (02 Dec 2020)
Sequence version 1 (01 May 2000)
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Protein

Protein CLP1 homolog

Gene

CLPS3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation (By similarity).

Functions in gametophyte, embryo and postembryotic development (PubMed:18971429).

UniRule annotation2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei33ATPUniRule annotation1
Binding sitei72ATP; via carbonyl oxygenUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi140 – 145ATPUniRule annotation6

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA processing
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein CLP1 homologUniRule annotation
Alternative name(s):
CLP-like protein 3
Protein CLP-SIMILAR PROTEIN 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CLPS3
Ordered Locus Names:At3g04680
ORF Names:F7O18.15
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G04680

The Arabidopsis Information Resource

More...
TAIRi
locus:2084938, AT3G04680

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004219231 – 444Protein CLP1 homologAdd BLAST444

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9SR06

PRoteomics IDEntifications database

More...
PRIDEi
Q9SR06

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
246753

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SR06, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9SR06, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PCFS4 and SYM5.

Forms a complex with cleavage and polyadenylation specificity factor (CPSF) subunits CPSF30, CPSF100, PCFS1, PCFS4, PCFS5, CPSF160 and FY.

4 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
4961, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q9SR06, 4 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT3G04680.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9SR06

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Clp1 family. Clp1 subfamily.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2749, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_018195_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9SR06

Identification of Orthologs from Complete Genome Data

More...
OMAi
KVAIFTY

Database of Orthologous Groups

More...
OrthoDBi
814241at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9SR06

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.1030, 1 hit
3.30.70.2410, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_03035, Clp1, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028606, Clp1
IPR010655, Clp1_C
IPR038238, Clp1_C_sf
IPR032324, Clp1_N
IPR038239, Clp1_N_sf
IPR032319, CLP1_P
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06807, Clp1, 1 hit
PF16573, CLP1_N, 1 hit
PF16575, CLP1_P, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9SR06-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAYGGPSMNP PALSGAVPGS ANLKQVKLER ESELRIEVSE EPLRLRVVNG
60 70 80 90 100
TAEIFGSELP PEIWRTFPPR MKFAVFTWYG ATIEMDGVTE TDYTADETPM
110 120 130 140 150
VSYINVHAIL DARRRFAKAS TSNDPESSQG PRVIVVGPTD SGKSTLTKML
160 170 180 190 200
LSWAAKQGWR PTFVDLDVGQ GSITIPGSIA AAPIEMPLDP VEGFPLDMAL
210 220 230 240 250
VYYYGHASPN MNVELYKALV KELAQVLEKQ FVGNPESRAA GMVINTMGWI
260 270 280 290 300
EGIGYELLLH AIDTFNASVV LVLGQEKLFS RLKDVLRSKS NVDVVKLHKS
310 320 330 340 350
GGVVARVKEV RKRSRNFKIQ EYFYGLSKEL SPYANTSSFS DLQVFRIGGG
360 370 380 390 400
PQAPKSALPA GSTSVSNPLR VTPVNIDDRD LLHSVLAVSY AEEPDQIISS
410 420 430 440
NVSGFVYVTE VNVQKKKITY LAPSPGTLPS KLLVAGSLAW LESV
Length:444
Mass (Da):48,421
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i04968918D3A539AA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC011437 Genomic DNA Translation: AAF04897.1
CP002686 Genomic DNA Translation: AEE74118.1
CP002686 Genomic DNA Translation: AEE74119.1
CP002686 Genomic DNA Translation: ANM65538.1
AY062866 mRNA Translation: AAL32944.1
AY128751 mRNA Translation: AAM91151.1

NCBI Reference Sequences

More...
RefSeqi
NP_001319471.1, NM_001337539.1
NP_001327497.1, NM_001337540.1
NP_187119.1, NM_111340.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G04680.1; AT3G04680.1; AT3G04680
AT3G04680.2; AT3G04680.2; AT3G04680
AT3G04680.3; AT3G04680.3; AT3G04680

Database of genes from NCBI RefSeq genomes

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GeneIDi
819626

Gramene; a comparative resource for plants

More...
Gramenei
AT3G04680.1; AT3G04680.1; AT3G04680
AT3G04680.2; AT3G04680.2; AT3G04680
AT3G04680.3; AT3G04680.3; AT3G04680

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G04680

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011437 Genomic DNA Translation: AAF04897.1
CP002686 Genomic DNA Translation: AEE74118.1
CP002686 Genomic DNA Translation: AEE74119.1
CP002686 Genomic DNA Translation: ANM65538.1
AY062866 mRNA Translation: AAL32944.1
AY128751 mRNA Translation: AAM91151.1
RefSeqiNP_001319471.1, NM_001337539.1
NP_001327497.1, NM_001337540.1
NP_187119.1, NM_111340.3

3D structure databases

SMRiQ9SR06
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4961, 9 interactors
IntActiQ9SR06, 4 interactors
STRINGi3702.AT3G04680.1

Proteomic databases

PaxDbiQ9SR06
PRIDEiQ9SR06
ProteomicsDBi246753

Genome annotation databases

EnsemblPlantsiAT3G04680.1; AT3G04680.1; AT3G04680
AT3G04680.2; AT3G04680.2; AT3G04680
AT3G04680.3; AT3G04680.3; AT3G04680
GeneIDi819626
GrameneiAT3G04680.1; AT3G04680.1; AT3G04680
AT3G04680.2; AT3G04680.2; AT3G04680
AT3G04680.3; AT3G04680.3; AT3G04680
KEGGiath:AT3G04680

Organism-specific databases

AraportiAT3G04680
TAIRilocus:2084938, AT3G04680

Phylogenomic databases

eggNOGiKOG2749, Eukaryota
HOGENOMiCLU_018195_1_0_1
InParanoidiQ9SR06
OMAiKVAIFTY
OrthoDBi814241at2759
PhylomeDBiQ9SR06

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9SR06

Gene expression databases

ExpressionAtlasiQ9SR06, baseline and differential
GenevisibleiQ9SR06, AT

Family and domain databases

Gene3Di2.60.120.1030, 1 hit
3.30.70.2410, 1 hit
HAMAPiMF_03035, Clp1, 1 hit
InterProiView protein in InterPro
IPR028606, Clp1
IPR010655, Clp1_C
IPR038238, Clp1_C_sf
IPR032324, Clp1_N
IPR038239, Clp1_N_sf
IPR032319, CLP1_P
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF06807, Clp1, 1 hit
PF16573, CLP1_N, 1 hit
PF16575, CLP1_P, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCLP1_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SR06
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2013
Last sequence update: May 1, 2000
Last modified: December 2, 2020
This is version 124 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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