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Entry version 131 (11 Dec 2019)
Sequence version 1 (01 May 2000)
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Protein

Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

Gene

EMB3004

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=685 µM for shikimate1 Publication
  2. KM=131 µM for NADP1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: chorismate biosynthesis

    This protein is involved in step 3 and 4 of the subpathway that synthesizes chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate.
    Proteins known to be involved in the 7 steps of the subpathway in this organism are:
    1. Phospho-2-dehydro-3-deoxyheptonate aldolase, Phospho-2-dehydro-3-deoxyheptonate aldolase (DHS2), Phospho-2-dehydro-3-deoxyheptonate aldolase (AXX17_At4g38330), Phospho-2-dehydro-3-deoxyheptonate aldolase (At4g33510), Phospho-2-dehydro-3-deoxyheptonate aldolase 2, chloroplastic (DHS2), Phospho-2-dehydro-3-deoxyheptonate aldolase (At4g33510), Phospho-2-dehydro-3-deoxyheptonate aldolase (AXX17_At4g45420), Phospho-2-dehydro-3-deoxyheptonate aldolase (At1g22410), Phospho-2-dehydro-3-deoxyheptonate aldolase, Phospho-2-dehydro-3-deoxyheptonate aldolase 1, chloroplastic (DHS1), Phospho-2-dehydro-3-deoxyheptonate aldolase (AXX17_At1g23540)
    2. 3-dehydroquinate synthase, chloroplastic (DHQS), DHQ_synthase domain-containing protein (AXX17_At5g66050)
    3. Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic (EMB3004)
    4. Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic (EMB3004)
    5. Shikimate kinase 1, chloroplastic (SK1), Shikimate kinase 2, chloroplastic (SK2)
    6. 3-phosphoshikimate 1-carboxyvinyltransferase (At2g45300), 3-phosphoshikimate 1-carboxyvinyltransferase (F27K7.11), 3-phosphoshikimate 1-carboxyvinyltransferase (AXX17_At1g42980), 3-phosphoshikimate 1-carboxyvinyltransferase, 3-phosphoshikimate 1-carboxyvinyltransferase (AXX17_At2g42890), 3-phosphoshikimate 1-carboxyvinyltransferase, chloroplastic (At2g45300)
    7. Chorismate synthase (At1g48850), Chorismate synthase, chloroplastic (EMB1144), Chorismate synthase (EMB1144), Chorismate synthase (EMB1144), Chorismate synthase (AXX17_At1g42970)
    This subpathway is part of the pathway chorismate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate, the pathway chorismate biosynthesis and in Metabolic intermediate biosynthesis.

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei214Proton acceptor; for 3-dehydroquinate dehydratase activity1
    Active sitei241Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei279Substrate; for 3-dehydroquinate dehydratase activity1
    Binding sitei336Substrate; for shikimate dehydrogenase activity1
    Binding sitei338Substrate; for shikimate dehydrogenase activity1
    Active sitei385For shikimate dehydrogenase activity1
    Binding sitei406Substrate; for shikimate dehydrogenase activity1
    Active sitei423For shikimate dehydrogenase activity1
    Binding sitei550Substrate; for shikimate dehydrogenase activity1
    Binding sitei578Substrate; for shikimate dehydrogenase activity1
    Binding sitei582Substrate; for shikimate dehydrogenase activity1

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionLyase, Multifunctional enzyme, Oxidoreductase
    Biological processAmino-acid biosynthesis, Aromatic amino acid biosynthesis
    LigandNADP

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    ARA:AT3G06350-MONOMER
    MetaCyc:AT3G06350-MONOMER

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    4.2.1.10 399

    SABIO-RK: Biochemical Reaction Kinetics Database

    More...
    SABIO-RKi
    Q9SQT8

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...
    UniPathwayi
    UPA00053;UER00086
    UPA00053;UER00087

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic
    Short name:
    DHQ-SDH protein
    Alternative name(s):
    DHQase-SORase
    Protein EMBRYO DEFECTIVE 3004
    Including the following 2 domains:
    Dehydroquinate dehydratase (EC:4.2.1.10)
    Short name:
    DHQ
    Shikimate dehydrogenase (EC:1.1.1.25)
    Short name:
    SDH
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:EMB3004
    Ordered Locus Names:At3g06350
    ORF Names:F24P17.18
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

    Organism-specific databases

    Arabidopsis Information Portal

    More...
    Araporti
    AT3G06350

    The Arabidopsis Information Resource

    More...
    TAIRi
    locus:2081036 AT3G06350

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Chloroplast, Plastid

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi336S → A: 13-fold decrease in substrate affinity but almost no change in activity. 1 Publication1
    Mutagenesisi338S → A: 10-fold decrease in activity, and 9-fold decrease in substrate affinity. 1 Publication1
    Mutagenesisi385K → A: Strongly reduced shikimate dehydrogenase activity, but minor change in substrate affinity. 1 Publication1
    Mutagenesisi385K → N: Strongly reduced shikimate dehydrogenase activity, but no change in substrate affinity. 1 Publication1
    Mutagenesisi423D → A: Loss of shikimate dehydrogenase activity. 1 Publication1
    Mutagenesisi423D → N: Reduced shikimate dehydrogenase activity, but no change in substrate affinity. 1 Publication1
    Mutagenesisi550Y → F or A: 100-fold decrease in activity, and 2-fold decrease in substrate affinity. 1 Publication1

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 66ChloroplastSequence analysisAdd BLAST66
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025064567 – 603Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplasticAdd BLAST537

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q9SQT8

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q9SQT8

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    Q9SQT8

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    Gene expression databases

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q9SQT8 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q9SQT8 AT

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Monomer.

    1 Publication

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    3702.AT3G06350.1

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    Secondary structure

    1603
    Legend: HelixTurnBeta strandPDB Structure known for this area
    Show more details

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q9SQT8

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    Protein Data Bank in Europe - Knowledge Base

    More...
    PDBe-KBi
    Search...

    Miscellaneous databases

    Relative evolutionary importance of amino acids within a protein sequence

    More...
    EvolutionaryTracei
    Q9SQT8

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni96 – 3133-dehydroquinate dehydrataseAdd BLAST218
    Regioni328 – 558Shikimate dehydrogenaseAdd BLAST231

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    In the N-terminal section; belongs to the type-I 3-dehydroquinase family.Curated
    In the C-terminal section; belongs to the shikimate dehydrogenase family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0692 Eukaryota
    COG0169 LUCA
    COG0710 LUCA

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000237875

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q9SQT8

    KEGG Orthology (KO)

    More...
    KOi
    K13832

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    RSMEPSN

    Database of Orthologous Groups

    More...
    OrthoDBi
    187464at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q9SQT8

    Family and domain databases

    Conserved Domains Database

    More...
    CDDi
    cd00502 DHQase_I, 1 hit

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    3.20.20.70, 1 hit

    HAMAP database of protein families

    More...
    HAMAPi
    MF_00214 AroD, 1 hit
    MF_00222 Shikimate_DH_AroE, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR013785 Aldolase_TIM
    IPR001381 DHquinase_I
    IPR036291 NAD(P)-bd_dom_sf
    IPR041121 SDH_C
    IPR011342 Shikimate_DH
    IPR013708 Shikimate_DH-bd_N
    IPR022893 Shikimate_DH_fam
    IPR006151 Shikm_DH/Glu-tRNA_Rdtase

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF01487 DHquinase_I, 1 hit
    PF18317 SDH_C, 1 hit
    PF01488 Shikimate_DH, 1 hit
    PF08501 Shikimate_dh_N, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF51735 SSF51735, 1 hit

    TIGRFAMs; a protein family database

    More...
    TIGRFAMsi
    TIGR01093 aroD, 1 hit
    TIGR00507 aroE, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9SQT8-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MAASSTNARL TNPPRLLSKP RLSPTSVANL RFPAADFSTR FFADSSSPRL
    60 70 80 90 100
    RSVPFPVVFS DQRRRRSMEP SNVYVASNST EMEIGSHDIV KNPSLICAPV
    110 120 130 140 150
    MADSIDKMVI ETSKAHELGA DLVEIRLDWL KDFNPLEDLK TIIKKSPLPT
    160 170 180 190 200
    LFTYRPKWEG GQYEGDENER RDVLRLAMEL GADYIDVELQ VASEFIKSID
    210 220 230 240 250
    GKKPGKFKVI VSSHNYQNTP SVEDLDGLVA RIQQTGADIV KIATTAVDIA
    260 270 280 290 300
    DVARMFHITS KAQVPTIGLV MGERGLMSRI LCSKFGGYLT FGTLDSSKVS
    310 320 330 340 350
    APGQPTIKDL LDLYNFRRIG PDTKVYGIIG KPVSHSKSPI VHNQAFKSVD
    360 370 380 390 400
    FNGVYVHLLV DNLVSFLQAY SSSDFAGFSC TIPHKEAALQ CCDEVDPLAK
    410 420 430 440 450
    SIGAVNTILR RKSDGKLLGY NTDCIGSISA IEDGLRSSGD PSSVPSSSSP
    460 470 480 490 500
    LASKTVVVIG AGGAGKALAY GAKEKGAKVV IANRTYERAL ELAEAIGGKA
    510 520 530 540 550
    LSLTDLDNYH PEDGMVLANT TSMGMQPNVE ETPISKDALK HYALVFDAVY
    560 570 580 590 600
    TPRITRLLRE AEESGAITVS GSEMFVRQAY EQFEIFTGLP APKELYWQIM

    SKY
    Length:603
    Mass (Da):65,796
    Last modified:May 1, 2000 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4DAAB35F594E7CB6
    GO

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti491E → K in BAD94599 (Ref. 5) Curated1
    Sequence conflicti557L → Q in AAS76684 (Ref. 3) Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AC011623 Genomic DNA Translation: AAF08579.1
    CP002686 Genomic DNA Translation: AEE74381.1
    BT012197 mRNA Translation: AAS76684.1
    AY736474 mRNA Translation: AAW63134.1
    AK220988 mRNA Translation: BAD94599.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_187286.1, NM_111510.4

    Genome annotation databases

    Ensembl plant genome annotation project

    More...
    EnsemblPlantsi
    AT3G06350.1; AT3G06350.1; AT3G06350

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    819809

    Gramene; a comparative resource for plants

    More...
    Gramenei
    AT3G06350.1; AT3G06350.1; AT3G06350

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    ath:AT3G06350

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AC011623 Genomic DNA Translation: AAF08579.1
    CP002686 Genomic DNA Translation: AEE74381.1
    BT012197 mRNA Translation: AAS76684.1
    AY736474 mRNA Translation: AAW63134.1
    AK220988 mRNA Translation: BAD94599.1
    RefSeqiNP_187286.1, NM_111510.4

    3D structure databases

    Select the link destinations:

    Protein Data Bank Europe

    More...
    PDBei

    Protein Data Bank RCSB

    More...
    RCSB PDBi

    Protein Data Bank Japan

    More...
    PDBji
    Links Updated
    PDB entryMethodResolution (Å)ChainPositionsPDBsum
    2GPTX-ray1.95A90-603[»]
    2O7QX-ray2.20A90-603[»]
    2O7SX-ray1.78A90-603[»]
    6BMBX-ray2.08A90-603[»]
    6BMQX-ray2.08A90-603[»]
    SMRiQ9SQT8
    ModBaseiSearch...
    PDBe-KBiSearch...

    Protein-protein interaction databases

    STRINGi3702.AT3G06350.1

    PTM databases

    iPTMnetiQ9SQT8

    Proteomic databases

    PaxDbiQ9SQT8
    PRIDEiQ9SQT8

    Genome annotation databases

    EnsemblPlantsiAT3G06350.1; AT3G06350.1; AT3G06350
    GeneIDi819809
    GrameneiAT3G06350.1; AT3G06350.1; AT3G06350
    KEGGiath:AT3G06350

    Organism-specific databases

    AraportiAT3G06350
    TAIRilocus:2081036 AT3G06350

    Phylogenomic databases

    eggNOGiKOG0692 Eukaryota
    COG0169 LUCA
    COG0710 LUCA
    HOGENOMiHOG000237875
    InParanoidiQ9SQT8
    KOiK13832
    OMAiRSMEPSN
    OrthoDBi187464at2759
    PhylomeDBiQ9SQT8

    Enzyme and pathway databases

    UniPathwayiUPA00053;UER00086
    UPA00053;UER00087
    BioCyciARA:AT3G06350-MONOMER
    MetaCyc:AT3G06350-MONOMER
    BRENDAi4.2.1.10 399
    SABIO-RKiQ9SQT8

    Miscellaneous databases

    EvolutionaryTraceiQ9SQT8

    Protein Ontology

    More...
    PROi
    PR:Q9SQT8

    Gene expression databases

    ExpressionAtlasiQ9SQT8 baseline and differential
    GenevisibleiQ9SQT8 AT

    Family and domain databases

    CDDicd00502 DHQase_I, 1 hit
    Gene3Di3.20.20.70, 1 hit
    HAMAPiMF_00214 AroD, 1 hit
    MF_00222 Shikimate_DH_AroE, 1 hit
    InterProiView protein in InterPro
    IPR013785 Aldolase_TIM
    IPR001381 DHquinase_I
    IPR036291 NAD(P)-bd_dom_sf
    IPR041121 SDH_C
    IPR011342 Shikimate_DH
    IPR013708 Shikimate_DH-bd_N
    IPR022893 Shikimate_DH_fam
    IPR006151 Shikm_DH/Glu-tRNA_Rdtase
    PfamiView protein in Pfam
    PF01487 DHquinase_I, 1 hit
    PF18317 SDH_C, 1 hit
    PF01488 Shikimate_DH, 1 hit
    PF08501 Shikimate_dh_N, 1 hit
    SUPFAMiSSF51735 SSF51735, 1 hit
    TIGRFAMsiTIGR01093 aroD, 1 hit
    TIGR00507 aroE, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDHQSD_ARATH
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SQT8
    Secondary accession number(s): Q3ZLP7, Q56ZH7, Q6NLY1
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
    Last sequence update: May 1, 2000
    Last modified: December 11, 2019
    This is version 131 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    3D-structure, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families
    4. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
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