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Entry version 135 (11 Dec 2019)
Sequence version 1 (01 May 2000)
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Protein

ETHYLENE INSENSITIVE 3-like 1 protein

Gene

EIL1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable transcription factor acting as a positive regulator in the ethylene response pathway. Could bind the primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter.2 Publications

Miscellaneous

Loss-of-function mutations (EIL1-1 and EIL1-2) in the gene show a weak ethylene-insensitive phenotype.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, DNA-binding
Biological processEthylene signaling pathway, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ETHYLENE INSENSITIVE 3-like 1 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:EIL1
Ordered Locus Names:At2g27050
ORF Names:T20P8.10
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

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Araporti
AT2G27050

The Arabidopsis Information Resource

More...
TAIRi
locus:2059247 AT2G27050

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001134991 – 584ETHYLENE INSENSITIVE 3-like 1 proteinAdd BLAST584

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9SLH0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SLH0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9SLH0 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Acts as homodimer to bind the primary ethylene response element.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
2599, 14 interactors

Database of interacting proteins

More...
DIPi
DIP-34866N

Protein interaction database and analysis system

More...
IntActi
Q9SLH0, 10 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT2G27050.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9SLH0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili41 – 74Sequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi570 – 578Poly-Gln9

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the EIN3 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IFT4 Eukaryota
ENOG4110EBS LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000240021

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9SLH0

KEGG Orthology (KO)

More...
KOi
K14514

Identification of Orthologs from Complete Genome Data

More...
OMAi
MMEGNIF

Database of Orthologous Groups

More...
OrthoDBi
266873at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9SLH0

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.3180.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006957 EIN3
IPR023278 Ethylene_insens-like_DNA-bd

The PANTHER Classification System

More...
PANTHERi
PTHR33305 PTHR33305, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04873 EIN3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF116768 SSF116768, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9SLH0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMMFNEMGMY GNMDFFSSST SLDVCPLPQA EQEPVVEDVD YTDDEMDVDE
60 70 80 90 100
LEKRMWRDKM RLKRLKEQQS KCKEGVDGSK QRQSQEQARR KKMSRAQDGI
110 120 130 140 150
LKYMLKMMEV CKAQGFVYGI IPEKGKPVTG ASDNLREWWK DKVRFDRNGP
160 170 180 190 200
AAIAKYQSEN NISGGSNDCN SLVGPTPHTL QELQDTTLGS LLSALMQHCD
210 220 230 240 250
PPQRRFPLEK GVSPPWWPNG NEEWWPQLGL PNEQGPPPYK KPHDLKKAWK
260 270 280 290 300
VGVLTAVIKH MSPDIAKIRK LVRQSKCLQD KMTAKESATW LAIINQEEVV
310 320 330 340 350
ARELYPESCP PLSSSSSLGS GSLLINDCSE YDVEGFEKEQ HGFDVEERKP
360 370 380 390 400
EIVMMHPLAS FGVAKMQHFP IKEEVATTVN LEFTRKRKQN NDMNVMVMDR
410 420 430 440 450
SAGYTCENGQ CPHSKMNLGF QDRSSRDNHQ MVCPYRDNRL AYGASKFHMG
460 470 480 490 500
GMKLVVPQQP VQPIDLSGVG VPENGQKMIT ELMAMYDRNV QSNQTPPTLM
510 520 530 540 550
ENQSMVIDAK AAQNQQLNFN SGNQMFMQQG TNNGVNNRFQ MVFDSTPFDM
560 570 580
AAFDYRDDWQ TGAMEGMGKQ QQQQQQQQDV SIWF
Length:584
Mass (Da):66,495
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i471E1715D1483B11
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti74E → G in AAC49746 (PubMed:9215635).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF004213 mRNA Translation: AAC49746.1
AC005623 Genomic DNA Translation: AAC77863.1
CP002685 Genomic DNA Translation: AEC07930.1
AY065191 mRNA Translation: AAL38367.1
BT003344 mRNA Translation: AAO29962.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B84668

NCBI Reference Sequences

More...
RefSeqi
NP_180273.1, NM_128263.5

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G27050.1; AT2G27050.1; AT2G27050

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
817247

Gramene; a comparative resource for plants

More...
Gramenei
AT2G27050.1; AT2G27050.1; AT2G27050

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G27050

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF004213 mRNA Translation: AAC49746.1
AC005623 Genomic DNA Translation: AAC77863.1
CP002685 Genomic DNA Translation: AEC07930.1
AY065191 mRNA Translation: AAL38367.1
BT003344 mRNA Translation: AAO29962.1
PIRiB84668
RefSeqiNP_180273.1, NM_128263.5

3D structure databases

SMRiQ9SLH0
ModBaseiSearch...

Protein-protein interaction databases

BioGridi2599, 14 interactors
DIPiDIP-34866N
IntActiQ9SLH0, 10 interactors
STRINGi3702.AT2G27050.1

Proteomic databases

PaxDbiQ9SLH0

Genome annotation databases

EnsemblPlantsiAT2G27050.1; AT2G27050.1; AT2G27050
GeneIDi817247
GrameneiAT2G27050.1; AT2G27050.1; AT2G27050
KEGGiath:AT2G27050

Organism-specific databases

AraportiAT2G27050
TAIRilocus:2059247 AT2G27050

Phylogenomic databases

eggNOGiENOG410IFT4 Eukaryota
ENOG4110EBS LUCA
HOGENOMiHOG000240021
InParanoidiQ9SLH0
KOiK14514
OMAiMMEGNIF
OrthoDBi266873at2759
PhylomeDBiQ9SLH0

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9SLH0

Gene expression databases

ExpressionAtlasiQ9SLH0 baseline and differential
GenevisibleiQ9SLH0 AT

Family and domain databases

Gene3Di1.10.3180.10, 1 hit
InterProiView protein in InterPro
IPR006957 EIN3
IPR023278 Ethylene_insens-like_DNA-bd
PANTHERiPTHR33305 PTHR33305, 1 hit
PfamiView protein in Pfam
PF04873 EIN3, 1 hit
SUPFAMiSSF116768 SSF116768, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiEIL1_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SLH0
Secondary accession number(s): O23114
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: May 1, 2000
Last modified: December 11, 2019
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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