Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alcohol dehydrogenase-like 1

Gene

At1g22430

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A primary alcohol + NAD+ = an aldehyde + NADH.By similarity
A secondary alcohol + NAD+ = a ketone + NADH.By similarity

Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi53Zinc 1; catalyticBy similarity1
Metal bindingi55Zinc 1By similarity1
Binding sitei55NADBy similarity1
Binding sitei55SubstrateBy similarity1
Metal bindingi76Zinc 1; catalyticBy similarity1
Binding sitei76SubstrateBy similarity1
Metal bindingi106Zinc 2By similarity1
Metal bindingi109Zinc 2By similarity1
Metal bindingi112Zinc 2By similarity1
Metal bindingi120Zinc 2By similarity1
Metal bindingi185Zinc 1; catalyticBy similarity1
Binding sitei234NADBy similarity1
Binding sitei239NADBy similarity1
Binding sitei331NAD; via amide nitrogenBy similarity1
Binding sitei381NADBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi210 – 215NADBy similarity6
Nucleotide bindingi304 – 306NADBy similarity3

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, NAD, Zinc

Enzyme and pathway databases

BioCyciARA:AT1G22430-MONOMER
ReactomeiR-ATH-2161541 Abacavir metabolism
R-ATH-5365859 RA biosynthesis pathway
R-ATH-71384 Ethanol oxidation

Names & Taxonomyi

Protein namesi
Recommended name:
Alcohol dehydrogenase-like 1 (EC:1.1.1.1By similarity)
Gene namesi
Ordered Locus Names:At1g22430
ORF Names:F12K8.22
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G22430
TAIRilocus:2009522 AT1G22430

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002991831 – 388Alcohol dehydrogenase-like 1Add BLAST388

Proteomic databases

PaxDbiQ9SK86
PRIDEiQ9SK86

Expressioni

Gene expression databases

ExpressionAtlasiQ9SK86 baseline and differential
GenevisibleiQ9SK86 AT

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

BioGridi24088, 1 interactor
STRINGi3702.AT1G22430.1

Structurei

3D structure databases

ProteinModelPortaliQ9SK86
SMRiQ9SK86
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0022 Eukaryota
COG1062 LUCA
HOGENOMiHOG000294674
InParanoidiQ9SK86
KOiK00121
OMAiGTFRHHT
OrthoDBiEOG09360CLU
PhylomeDBiQ9SK86

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR002328 ADH_Zn_CS
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SUPFAMiSSF50129 SSF50129, 2 hits
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00059 ADH_ZINC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SK86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKTFFSSNE GKPITCKAAI CRKAGEALVI EDIHVDPPQA YEVRIKILCT
60 70 80 90 100
SLCHTDLTFW KLSFGPISRF PRILGHEAVG VVESIGENVD GFKQGDVVLP
110 120 130 140 150
VFHPYCEECK DCKSSKTNWC DRYAEDFISN TRRYGMASRF KDSSGEVIHH
160 170 180 190 200
FLFVSSFSEY TVVDIAHLVK ISPEIPVDKA ALLSCGVSTG IGAAWKVANV
210 220 230 240 250
EEGSTIAIFG LGAVGLAVAE GARLRGAAKI IGIDTNSDKF ELGKKFGFTD
260 270 280 290 300
FINPTLCGEK KISEVIKEMT EGGVDYSFEC VGLASLLNEA FISTRTGTGK
310 320 330 340 350
TVMLGMEKHA APISLGSFDL LRGRVICGSL FGGLKSKLDI PILVDHYLKK
360 370 380
ELNLDSFITH ELNFKEINKA FALLEEGKSL RCILWMDK
Length:388
Mass (Da):42,529
Last modified:May 1, 2000 - v1
Checksum:i6B604C871850B421
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006551 Genomic DNA Translation: AAF18534.1
CP002684 Genomic DNA Translation: AEE30240.1
CP002684 Genomic DNA Translation: AEE30241.1
AY093114 mRNA Translation: AAM13113.1
AY128821 mRNA Translation: AAM91221.1
PIRiD86357
RefSeqiNP_001031079.1, NM_001036002.1
NP_173659.1, NM_102092.6
UniGeneiAt.41602

Genome annotation databases

EnsemblPlantsiAT1G22430.1; AT1G22430.1; AT1G22430
AT1G22430.2; AT1G22430.2; AT1G22430
GeneIDi838849
GrameneiAT1G22430.1; AT1G22430.1; AT1G22430
AT1G22430.2; AT1G22430.2; AT1G22430
KEGGiath:AT1G22430

Similar proteinsi

Entry informationi

Entry nameiADHL1_ARATH
AccessioniPrimary (citable) accession number: Q9SK86
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health