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Entry version 125 (02 Dec 2020)
Sequence version 2 (01 Jun 2002)
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Protein

Probable sucrose-phosphatase 2

Gene

SPP2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the final step of sucrose synthesis.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: sucrose biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes sucrose from D-fructose 6-phosphate and UDP-alpha-D-glucose.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Sucrose-phosphate synthase (AXX17_At5g20260), Sucrose-phosphate synthase (AXX17_At5g10800), Probable sucrose-phosphate synthase 3 (SPS3), Probable sucrose-phosphate synthase 4 (SPS4), Sucrose-phosphate synthase (AT9943_LOCUS356), Sucrose-phosphate synthase 1 (SPS1), Probable sucrose-phosphate synthase 2 (SPS2), Sucrose-phosphate synthase (ATSPS4F), Sucrose-phosphate synthase (AN1_LOCUS21906), Sucrose-phosphate synthase (AT9943_LOCUS18861), Sucrose-phosphate synthase (AT5G20280), Sucrose-phosphate synthase (AN1_LOCUS17595), Sucrose-phosphate synthase (AT1G04920), Sucrose-phosphate synthase (AXX17_At1g04250), Sucrose-phosphate synthase (AT4G10120), Sucrose-phosphate synthase (AT5G11110), Sucrose-phosphate synthase (AT9943_LOCUS15172), Sucrose-phosphate synthase (C24_LOCUS21797), Sucrose-phosphate synthase (ATSPS4F)
  2. Sucrose-phosphatase (AN1_LOCUS15800), Probable sucrose-phosphatase 3b (SPP3B), Sucrose-phosphatase (C24_LOCUS4135), Sucrose-phosphatase (AXX17_At3g48700), Sucrose-phosphatase (AT9943_LOCUS13595), Sucrose-phosphatase (AT9943_LOCUS3609), Sucrose-phosphatase (AN1_LOCUS10037), Sucrose-phosphatase (AN1_LOCUS4249), Sucrose-phosphatase (AXX17_At2g32500), Sucrose-phosphatase (SPP2), Sucrose-phosphatase (SPP2), Sucrose-phosphatase (AXX17_At1g45630), Sucrose-phosphatase (SPP1), Sucrose-phosphatase (AXX17_At3g46760), Probable sucrose-phosphatase 1 (SPP1), Probable sucrose-phosphatase 2 (SPP2), Sucrose-phosphatase (C24_LOCUS15683), Probable sucrose-phosphatase 3a (SPP3A)
This subpathway is part of the pathway sucrose biosynthesis, which is itself part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sucrose from D-fructose 6-phosphate and UDP-alpha-D-glucose, the pathway sucrose biosynthesis and in Glycan biosynthesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandMagnesium

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT2G35840-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00371;UER00546

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable sucrose-phosphatase 2 (EC:3.1.3.24)
Short name:
AtSPP2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SPP2
Synonyms:SPP1
Ordered Locus Names:At2g35840
ORF Names:F11F19.25
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G35840

The Arabidopsis Information Resource

More...
TAIRi
locus:2039295, AT2G35840

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003506141 – 422Probable sucrose-phosphatase 2Add BLAST422

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9SJ66

PRoteomics IDEntifications database

More...
PRIDEi
Q9SJ66

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
234095

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SJ66, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9SJ66, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
3501, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT2G35840.3

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9SJ66

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sucrose phosphatase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S8I4, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_030534_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9SJ66

Identification of Orthologs from Complete Genome Data

More...
OMAi
FNLWELE

Database of Orthologous Groups

More...
OrthoDBi
612145at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9SJ66

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.1000, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036412, HAD-like_sf
IPR006379, HAD-SF_hydro_IIB
IPR023214, HAD_sf
IPR032710, NTF2-like_dom_sf
IPR013679, SPP_C
IPR006380, SPP_N
IPR012847, Sucrose_phosphatase_pln/cyn

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05116, S6PP, 1 hit
PF08472, S6PP_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54427, SSF54427, 1 hit
SSF56784, SSF56784, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01484, HAD-SF-IIB, 1 hit
TIGR01485, SPP_plant-cyano, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9SJ66-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERLTSPPRL MIVSDLDHTM VDHHDPENLS LLRFNSLWEH AYRHDSLLVF
60 70 80 90 100
STGRSPTLYK ELRKEKPLLT PDITIMSVGT EITYGNSMVP DHGWVEALNN
110 120 130 140 150
KWDLGIVKQE ASNFPELKLQ AETEQRPHKV SFYVEKSKAQ EVTKELSQRF
160 170 180 190 200
LKRGLDVKII YSGGMDLDIL PQGAGKGQAL AYLLKKLKTE GKLPVNTLAC
210 220 230 240 250
GDSGNDAELF SIPDVYGVMV SNAQEELLKW HAENAKDNPK VIHAKERCAG
260 270 280 290 300
GIIQAIGHFK LGPNLSPRDV SDFLEIKVEN VNPGHEVVKF FLFYERWRRG
310 320 330 340 350
EVENSEAYTA SLKASVHPGG VFVHPSGTEK SLRDTIDELR KYHGDKQGKK
360 370 380 390 400
FRVWADQVLA TDTTPGTWIV KLDKWEQDGD ERRCCTTTVK FTSKEGEGLV
410 420
WEHVQQTWSK ETMVKDDSSW II
Length:422
Mass (Da):47,855
Last modified:June 1, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6CC4B0D5A1AF4BCF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC007017 Genomic DNA Translation: AAD21473.2
CP002685 Genomic DNA Translation: AEC09168.1
CP002685 Genomic DNA Translation: AEC09169.1
CP002685 Genomic DNA Translation: AEC09170.1
CP002685 Genomic DNA Translation: ANM63145.1
AY054474 mRNA Translation: AAK96665.1
AY114634 mRNA Translation: AAM47953.1
AF283565 mRNA Translation: AAG31075.1
AY735594 mRNA Translation: AAU44464.1
AY954816 mRNA Translation: AAX55142.1

Protein sequence database of the Protein Information Resource

More...
PIRi
F84773

NCBI Reference Sequences

More...
RefSeqi
NP_001189687.1, NM_001202758.1
NP_001325253.1, NM_001336575.1
NP_565828.1, NM_129143.4
NP_973609.1, NM_201880.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G35840.1; AT2G35840.1; AT2G35840
AT2G35840.2; AT2G35840.2; AT2G35840
AT2G35840.3; AT2G35840.3; AT2G35840
AT2G35840.4; AT2G35840.4; AT2G35840

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
818157

Gramene; a comparative resource for plants

More...
Gramenei
AT2G35840.1; AT2G35840.1; AT2G35840
AT2G35840.2; AT2G35840.2; AT2G35840
AT2G35840.3; AT2G35840.3; AT2G35840
AT2G35840.4; AT2G35840.4; AT2G35840

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G35840

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007017 Genomic DNA Translation: AAD21473.2
CP002685 Genomic DNA Translation: AEC09168.1
CP002685 Genomic DNA Translation: AEC09169.1
CP002685 Genomic DNA Translation: AEC09170.1
CP002685 Genomic DNA Translation: ANM63145.1
AY054474 mRNA Translation: AAK96665.1
AY114634 mRNA Translation: AAM47953.1
AF283565 mRNA Translation: AAG31075.1
AY735594 mRNA Translation: AAU44464.1
AY954816 mRNA Translation: AAX55142.1
PIRiF84773
RefSeqiNP_001189687.1, NM_001202758.1
NP_001325253.1, NM_001336575.1
NP_565828.1, NM_129143.4
NP_973609.1, NM_201880.2

3D structure databases

SMRiQ9SJ66
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi3501, 2 interactors
STRINGi3702.AT2G35840.3

Proteomic databases

PaxDbiQ9SJ66
PRIDEiQ9SJ66
ProteomicsDBi234095

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
818157

Genome annotation databases

EnsemblPlantsiAT2G35840.1; AT2G35840.1; AT2G35840
AT2G35840.2; AT2G35840.2; AT2G35840
AT2G35840.3; AT2G35840.3; AT2G35840
AT2G35840.4; AT2G35840.4; AT2G35840
GeneIDi818157
GrameneiAT2G35840.1; AT2G35840.1; AT2G35840
AT2G35840.2; AT2G35840.2; AT2G35840
AT2G35840.3; AT2G35840.3; AT2G35840
AT2G35840.4; AT2G35840.4; AT2G35840
KEGGiath:AT2G35840

Organism-specific databases

AraportiAT2G35840
TAIRilocus:2039295, AT2G35840

Phylogenomic databases

eggNOGiENOG502S8I4, Eukaryota
HOGENOMiCLU_030534_1_0_1
InParanoidiQ9SJ66
OMAiFNLWELE
OrthoDBi612145at2759
PhylomeDBiQ9SJ66

Enzyme and pathway databases

UniPathwayiUPA00371;UER00546
BioCyciARA:AT2G35840-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9SJ66

Gene expression databases

ExpressionAtlasiQ9SJ66, baseline and differential
GenevisibleiQ9SJ66, AT

Family and domain databases

Gene3Di3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR036412, HAD-like_sf
IPR006379, HAD-SF_hydro_IIB
IPR023214, HAD_sf
IPR032710, NTF2-like_dom_sf
IPR013679, SPP_C
IPR006380, SPP_N
IPR012847, Sucrose_phosphatase_pln/cyn
PfamiView protein in Pfam
PF05116, S6PP, 1 hit
PF08472, S6PP_C, 1 hit
SUPFAMiSSF54427, SSF54427, 1 hit
SSF56784, SSF56784, 1 hit
TIGRFAMsiTIGR01484, HAD-SF-IIB, 1 hit
TIGR01485, SPP_plant-cyano, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPP2_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SJ66
Secondary accession number(s): Q5XVC8, Q940K7, Q9FUW2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: June 1, 2002
Last modified: December 2, 2020
This is version 125 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families
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