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Protein

Type IV inositol polyphosphate 5-phosphatase 9

Gene

IP5P9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Has phosphatase activity toward PtdIns(4,5)P2 and at a lower extent toward PtdIns(3,4,5)P3 but not toward Ins(1,4,5)P3. Functions in salt stress response by regulating reactive oxygen species (ROS) production, endocytosis, Ca2+ influx and stress-responsive genes expression.1 Publication

Catalytic activityi

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.1 Publication
1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3,4-diphosphate + phosphate.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Type IV inositol polyphosphate 5-phosphatase 91 Publication (EC:3.1.3.361 Publication, EC:3.1.3.861 Publication)
Short name:
At5PTase91 Publication
Gene namesi
Name:IP5P9Curated
Ordered Locus Names:At2g01900Imported
ORF Names:T23K3.9Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G01900
TAIRilocus:2059708 AT2G01900

Pathology & Biotechi

Disruption phenotypei

Increased salt sensitivity with reduced production of reactive oxygen species (ROS), reduced Ca2+ influx, as well as decreased fluid-phase endocytosis.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004332591 – 417Type IV inositol polyphosphate 5-phosphatase 9Add BLAST417

Proteomic databases

PaxDbiQ9SIS4

Expressioni

Tissue specificityi

Specifically expressed in roots.1 Publication

Gene expression databases

ExpressionAtlasiQ9SIS4 baseline and differential
GenevisibleiQ9SIS4 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G01900.1

Structurei

3D structure databases

ProteinModelPortaliQ9SIS4
SMRiQ9SIS4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni258 – 273Catalytic 1By similarityAdd BLAST16
Regioni339 – 354Catalytic 2By similarityAdd BLAST16

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0565 Eukaryota
COG5411 LUCA
HOGENOMiHOG000241161
InParanoidiQ9SIS4
OMAiCASHGRK
OrthoDBiEOG093608N0
PhylomeDBiQ9SIS4

Family and domain databases

Gene3Di3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000300 IPPc
PfamiView protein in Pfam
PF03372 Exo_endo_phos, 1 hit
SMARTiView protein in SMART
SM00128 IPPc, 1 hit
SUPFAMiSSF56219 SSF56219, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9SIS4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWPRLVANKI LRKSLGSNNF VADFPPNTDQ KLIEASGLAD ERSKSILHNQ
60 70 80 90 100
HKTTLLNYKV FVSTWNVGGI VPDDGLDMED LLETHKTPCD IYVLGFQEVV
110 120 130 140 150
PLRASNVLGS DNNKVSTKWN SLIRDALNKR ARPHRDEDLS ESKGINGISQ
160 170 180 190 200
DFRCIISKQM VGILITVWVR GDLWPYIRYP SVSCVGCGIM GCLGNKGSVS
210 220 230 240 250
VRFQLHETTF CFVCSHLASG GRDRDERQRN SDVNEILARS SFPRGSSLDL
260 270 280 290 300
PKKILDHDRV IFLGDLNYRI SLPEEKTRLL VESKKWNILL ENDQLRMEIM
310 320 330 340 350
NGQIFRGWQE GIVKFAPTYK YVPNSDLYYG CITYKKDEKK RAPAWCDRII
360 370 380 390 400
WYGNGLKQHE YTRGETKISD HRPVKAIFTT EITVTRRGKK IRNFFFSDRF
410
EERIGDIDSK DYSWIST
Length:417
Mass (Da):47,924
Last modified:May 1, 2000 - v1
Checksum:i13A4527DEC6A6B7B
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8AXD3A0A1P8AXD3_ARATH
DNAse I-like superfamily protein
At2g01900, T23K3.9, T23K3_9
408Annotation score:
A0A1P8AXI3A0A1P8AXI3_ARATH
DNAse I-like superfamily protein
At2g01900, T23K3.9, T23K3_9
425Annotation score:

Sequence cautioni

The sequence BX818920 differs from that shown. Sequencing errors.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007069 Genomic DNA Translation: AAD21781.1
CP002685 Genomic DNA Translation: AEC05514.1
BX818920 mRNA No translation available.
PIRiE84430
RefSeqiNP_178299.1, NM_126251.3

Genome annotation databases

EnsemblPlantsiAT2G01900.1; AT2G01900.1; AT2G01900
GeneIDi814721
GrameneiAT2G01900.1; AT2G01900.1; AT2G01900
KEGGiath:AT2G01900

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007069 Genomic DNA Translation: AAD21781.1
CP002685 Genomic DNA Translation: AEC05514.1
BX818920 mRNA No translation available.
PIRiE84430
RefSeqiNP_178299.1, NM_126251.3

3D structure databases

ProteinModelPortaliQ9SIS4
SMRiQ9SIS4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G01900.1

Proteomic databases

PaxDbiQ9SIS4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G01900.1; AT2G01900.1; AT2G01900
GeneIDi814721
GrameneiAT2G01900.1; AT2G01900.1; AT2G01900
KEGGiath:AT2G01900

Organism-specific databases

AraportiAT2G01900
TAIRilocus:2059708 AT2G01900

Phylogenomic databases

eggNOGiKOG0565 Eukaryota
COG5411 LUCA
HOGENOMiHOG000241161
InParanoidiQ9SIS4
OMAiCASHGRK
OrthoDBiEOG093608N0
PhylomeDBiQ9SIS4

Miscellaneous databases

PROiPR:Q9SIS4

Gene expression databases

ExpressionAtlasiQ9SIS4 baseline and differential
GenevisibleiQ9SIS4 AT

Family and domain databases

Gene3Di3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000300 IPPc
PfamiView protein in Pfam
PF03372 Exo_endo_phos, 1 hit
SMARTiView protein in SMART
SM00128 IPPc, 1 hit
SUPFAMiSSF56219 SSF56219, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiIP5P9_ARATH
AccessioniPrimary (citable) accession number: Q9SIS4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 24, 2015
Last sequence update: May 1, 2000
Last modified: October 10, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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Main funding by: National Institutes of Health

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