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Entry version 111 (31 Jul 2019)
Sequence version 2 (01 Mar 2001)
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Protein
Submitted name:

F1K23.2

Gene
N/A
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi318 – 329PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi359 – 370PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi796 – 807PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi837 – 848PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotationSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
F1K23.2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei78 – 96HelicalSequence analysisAdd BLAST19
Transmembranei103 – 129HelicalSequence analysisAdd BLAST27
Transmembranei149 – 172HelicalSequence analysisAdd BLAST24
Transmembranei217 – 234HelicalSequence analysisAdd BLAST18
Transmembranei246 – 267HelicalSequence analysisAdd BLAST22
Transmembranei425 – 443HelicalSequence analysisAdd BLAST19
Transmembranei503 – 523HelicalSequence analysisAdd BLAST21
Transmembranei529 – 550HelicalSequence analysisAdd BLAST22
Transmembranei600 – 620HelicalSequence analysisAdd BLAST21
Transmembranei640 – 661HelicalSequence analysisAdd BLAST22
Transmembranei673 – 697HelicalSequence analysisAdd BLAST25
Transmembranei722 – 739HelicalSequence analysisAdd BLAST18
Transmembranei899 – 917HelicalSequence analysisAdd BLAST19
Transmembranei937 – 957HelicalSequence analysisAdd BLAST21
Transmembranei978 – 996HelicalSequence analysisAdd BLAST19
Transmembranei1002 – 1021HelicalSequence analysisAdd BLAST20
Transmembranei1028 – 1049HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500433714622 – 1062Sequence analysisAdd BLAST1041

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9SHR0

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9SHR0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SHR0 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini305 – 340EF-handInterPro annotationAdd BLAST36
Domaini346 – 381EF-handInterPro annotationAdd BLAST36
Domaini783 – 818EF-handInterPro annotationAdd BLAST36
Domaini824 – 859EF-handInterPro annotationAdd BLAST36

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000148342

Database of Orthologous Groups

More...
OrthoDBi
435926at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9SHR0

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00051 EFh, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR039647 EF_hand_pair_protein_CML-like

The PANTHER Classification System

More...
PANTHERi
PTHR10891 PTHR10891, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13499 EF-hand_7, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00054 EFh, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473 SSF47473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00018 EF_HAND_1, 4 hits
PS50222 EF_HAND_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9SHR0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARLTLFLSF LSLALVSVVN CRVLSSVSED NNSSILVSDG VQDRSSNDFL
60 70 80 90 100
SLNPPNLSES ACVHVYGFLP CADNIEGYVF QVFSFGCLLI IGEYFLSKGR
110 120 130 140 150
SKLFVIFEVG FFGGIIFPLL TMFPRIALIL STGLIGSREI ANSMTGNNVA
160 170 180 190 200
VTVGYSVFAL TMQWGACVVF GLSGLRSDDQ SITCDISSPR RQVKKSINLL
210 220 230 240 250
KNLAGASIRA DPKNKKAAGI MLLTLLPFVL VTFSETFHIK SWDDNMVLVT
260 270 280 290 300
LIFSGSATVL YFVYLYFDKA DQVKSLEYAK FELMSEVHKH LQNFSPQSLI
310 320 330 340 350
RNGQLCQESL KSLFKKFDVN KDGKIQVSEL KDLTVDFGVL GRVKCDINEL
360 370 380 390 400
ATTLLADFDS NRDGEIDETE FAIGIEKWLK QYKFSFNGTE SQGEDIAEDD
410 420 430 440 450
GVLKVEQLLK GCLFTKLLTK RTLKAVIEVI IGITIVSFLA MPFMMNIELL
460 470 480 490 500
SVSAGVPSFY VVFAVIPLAR NLKNALSAHF CRKKEKAKIT SDTFSEIYRD
510 520 530 540 550
VTLNNLLGIT IILAIVYIRG LTWDYSTEVL IIVIVGLIIA LISVVNCRVL
560 570 580 590 600
SSLSEKDSIL VSDGVQDGSS YEFLSLDPPN DITKNMCVHV YDFLPCADNV
610 620 630 640 650
AGYVFQVFSF GCILIIGEYF LTKGRTKLFL IFEVGFYGGI IFPLLTMFPR
660 670 680 690 700
IALILSTGLV GSREMASSRV GNIIGVTVGY SVFALTIQWG ACILFGLSGT
710 720 730 740 750
KPEQPIDLSA ASVEADITNK KSAGIMLLTI LPFILVFFVK NSQYFDRDDQ
760 770 780 790 800
AKSLDHARFE LMSEVHKHLQ IFSPKSLIRD GQLNQESLKR LFQKIDANGD
810 820 830 840 850
GKIQVAELKD LTVEFGMIGR VKCHIDKLVH TLVDDFDRDG DREIDEAEFE
860 870 880 890 900
IGIKKWLNQY KFSFDTTVPP REDQAEGVPI LKVEKPEQSL VKKLLSWRTL
910 920 930 940 950
RASLEVILGM LVVIYLARPF MMNIQLLSES AGVPSFYVVF VVIPLARNLK
960 970 980 990 1000
NTLSAHFCRK KDKAKITSDT FSEIYKDVTM NNLMGISIIL AIVYARELVW
1010 1020 1030 1040 1050
DYTTEVLIIV IVGLLIGLPA YVRTTYPFWI CLLAFALYFI SLVVVYFHFM
1060
SLEKGTTVTF NK
Length:1,062
Mass (Da):118,517
Last modified:March 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA2A2BD2649E58543
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC007508 Genomic DNA Translation: AAF24539.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G29025.1; AT1G29025.1; AT1G29025

Gramene; a comparative resource for plants

More...
Gramenei
AT1G29025.1; AT1G29025.1; AT1G29025

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007508 Genomic DNA Translation: AAF24539.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiQ9SHR0

Proteomic databases

PRIDEiQ9SHR0

Genome annotation databases

EnsemblPlantsiAT1G29025.1; AT1G29025.1; AT1G29025
GrameneiAT1G29025.1; AT1G29025.1; AT1G29025

Phylogenomic databases

HOGENOMiHOG000148342
OrthoDBi435926at2759
PhylomeDBiQ9SHR0

Gene expression databases

ExpressionAtlasiQ9SHR0 baseline and differential

Family and domain databases

CDDicd00051 EFh, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR039647 EF_hand_pair_protein_CML-like
PANTHERiPTHR10891 PTHR10891, 3 hits
PfamiView protein in Pfam
PF13499 EF-hand_7, 2 hits
SMARTiView protein in SMART
SM00054 EFh, 4 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 4 hits
PS50222 EF_HAND_2, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9SHR0_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SHR0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: March 1, 2001
Last modified: July 31, 2019
This is version 111 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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