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Protein

Glutathione S-transferase U26

Gene

GSTU26

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB). May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.1 Publication

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  • glutathione transferase activity Source: TAIR

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • response to cold Source: TAIR
  • response to herbicide Source: TAIR
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification, Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U26 (EC:2.5.1.18)
Short name:
AtGSTU26
Alternative name(s):
GST class-tau member 26
Gene namesi
Name:GSTU26
Ordered Locus Names:At1g17190
ORF Names:F20D23.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G17190
TAIRilocus:2020302 AT1G17190

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135711 – 220Glutathione S-transferase U26Add BLAST220

Proteomic databases

PaxDbiQ9SHH8

Expressioni

Inductioni

By alachlor, metolachlor and benoxacor.1 Publication

Gene expression databases

ExpressionAtlasiQ9SHH8 baseline and differential
GenevisibleiQ9SHH8 AT

Interactioni

Protein-protein interaction databases

BioGridi23530, 4 interactors
IntActiQ9SHH8, 4 interactors
STRINGi3702.AT1G17190.1

Structurei

3D structure databases

ProteinModelPortaliQ9SHH8
SMRiQ9SHH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 83GST N-terminalAdd BLAST80
Domaini89 – 210GST C-terminalAdd BLAST122

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni14 – 15Glutathione bindingBy similarity2
Regioni40 – 41Glutathione bindingBy similarity2
Regioni54 – 55Glutathione bindingBy similarity2
Regioni67 – 68Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406 Eukaryota
ENOG410XSIX LUCA
HOGENOMiHOG000125749
InParanoidiQ9SHH8
KOiK00799
OMAiWATMGEE
OrthoDBiEOG09360PCQ
PhylomeDBiQ9SHH8

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SHH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANDQVILLD YWPSMFGMRT KMALAEKGVK YEYKETDPWV KTPLLIEMNP
60 70 80 90 100
IHKKIPVLIH NGKPICESLI QLEYIDEVWS DASPILPSDP YQKSRARFWA
110 120 130 140 150
EFIDKKFYDP SWKVWATMGE EHAAVKKELL EHFKTLETEL GDKPYYGGEV
160 170 180 190 200
FGYLDIALMG YYSWFKAMEK FGEFSIETEF PILTTWTKRC LERESVVKAL
210 220
ADSDRIIEYV YVLRKKFGAA
Length:220
Mass (Da):25,779
Last modified:May 1, 2000 - v1
Checksum:iCE898118920E502A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ306688 mRNA Translation: CAC36895.1
AC007651 Genomic DNA Translation: AAD50014.1
CP002684 Genomic DNA Translation: AEE29556.1
BT004605 mRNA Translation: AAO42851.1
AK227997 mRNA Translation: BAE99962.1
PIRiA86308
RefSeqiNP_173162.1, NM_101580.4
UniGeneiAt.10364

Genome annotation databases

EnsemblPlantsiAT1G17190.1; AT1G17190.1; AT1G17190
GeneIDi838290
GrameneiAT1G17190.1; AT1G17190.1; AT1G17190
KEGGiath:AT1G17190

Similar proteinsi

Entry informationi

Entry nameiGSTUQ_ARATH
AccessioniPrimary (citable) accession number: Q9SHH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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