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Entry version 131 (16 Oct 2019)
Sequence version 1 (01 May 2000)
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Protein

Phenylalanine--tRNA ligase beta subunit, cytoplasmic

Gene

At1g72550

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi361MagnesiumPROSITE-ProRule annotation1
Metal bindingi367Magnesium; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi370MagnesiumPROSITE-ProRule annotation1
Metal bindingi371MagnesiumPROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phenylalanine--tRNA ligase beta subunit, cytoplasmicCurated (EC:6.1.1.20Curated)
Alternative name(s):
Phenylalanyl-tRNA synthetase beta subunitCurated
Short name:
PheRSCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At1g72550
ORF Names:F28P22.26
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G72550

The Arabidopsis Information Resource

More...
TAIRi
locus:2030290 AT1G72550

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001270201 – 598Phenylalanine--tRNA ligase beta subunit, cytoplasmicAdd BLAST598

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9SGE9

PRoteomics IDEntifications database

More...
PRIDEi
Q9SGE9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9SGE9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SGE9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9SGE9 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Tetramer of two alpha and two beta subunits.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
28806, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT1G72550.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9SGE9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini303 – 383B5PROSITE-ProRule annotationAdd BLAST81

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2472 Eukaryota
COG0072 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000105095

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9SGE9

KEGG Orthology (KO)

More...
KOi
K01890

Identification of Orthologs from Complete Genome Data

More...
OMAi
TIGVKRD

Database of Orthologous Groups

More...
OrthoDBi
378921at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9SGE9

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00769 PheRS_beta_core, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.50.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005146 B3/B4_tRNA-bd
IPR009061 DNA-bd_dom_put_sf
IPR004531 Phe-tRNA-synth_IIc_bsu_arc
IPR020825 Phe-tRNA_synthase_B3/B4
IPR041616 PheRS_beta_core
IPR040659 PhetRS_B1
IPR005147 tRNA_synthase_B5-dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03483 B3_4, 1 hit
PF03484 B5, 1 hit
PF18262 PhetRS_B1, 1 hit
PF17759 tRNA_synthFbeta, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00873 B3_4, 1 hit
SM00874 B5, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46955 SSF46955, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00471 pheT_arch, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51483 B5, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 1 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9SGE9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPTISVGRDR LFAALGESYT QEKFEELCFS FGIELDDVTT EKAIIRKEKH
60 70 80 90 100
IDEEADDDEE IIYKIEIPAN RPDLLCLEGL AQSLRVFIEK QEIPTYTLAD
110 120 130 140 150
ISKDKILQMN VKPETSKIRP FVVCAVLRGV TFDEARYNSF IDLQDKLHQN
160 170 180 190 200
ICRRRSLVAI GTHDLDTLQG PFTYEALPPT DINFVPLKQT KSFRADELIE
210 220 230 240 250
FYKSDMKLKK FLHIIENSPV FPVLYDSKRT VLSLPPIING AHSAITLQTK
260 270 280 290 300
NVFIECTATD LTKAKIVLNT MVTTFSEFCA RKFEIEPVEV TYDDGKSYIY
310 320 330 340 350
PDLAVYDMEV PLSFITDSIG VSLKVEQVTS LLTRMQLQAE QAKSSDNQCA
360 370 380 390 400
IKVHVPPSRS DVLHPCDVME DVAIAYGFNN IPTRKPASIK PLTLNELTDL
410 420 430 440 450
LRIEIAMCVY TEVVTWLLCS HKENFAMLNR EDVNSAVIVG NPRSADFEAM
460 470 480 490 500
RRALMPGLLK TVGHNNKYPK PIKIFEISDV VMLDESKDVG ASNRRHLAAL
510 520 530 540 550
YCGATSGFEL IHGLVDRIME VMAIPFLTIH ENNVPINEKD GYYVKLSQEP
560 570 580 590
EFLPGRQASI IVRGKHIGNF GIVHPEVLNN FDIPDPCSYL ELDIEAIL
Length:598
Mass (Da):67,543
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i271EE650875410A2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4IDD6F4IDD6_ARATH
tRNA synthetase beta subunit family...
At1g72550, F28P22.26, F28P22_26
584Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC010926 Genomic DNA Translation: AAG51865.1
CP002684 Genomic DNA Translation: AEE35338.1
AY062707 mRNA Translation: AAL32785.1
AY128795 mRNA Translation: AAM91195.1

Protein sequence database of the Protein Information Resource

More...
PIRi
H96749

NCBI Reference Sequences

More...
RefSeqi
NP_177399.1, NM_105914.5 [Q9SGE9-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G72550.1; AT1G72550.1; AT1G72550 [Q9SGE9-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
843587

Gramene; a comparative resource for plants

More...
Gramenei
AT1G72550.1; AT1G72550.1; AT1G72550 [Q9SGE9-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G72550

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010926 Genomic DNA Translation: AAG51865.1
CP002684 Genomic DNA Translation: AEE35338.1
AY062707 mRNA Translation: AAL32785.1
AY128795 mRNA Translation: AAM91195.1
PIRiH96749
RefSeqiNP_177399.1, NM_105914.5 [Q9SGE9-1]

3D structure databases

SMRiQ9SGE9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi28806, 2 interactors
STRINGi3702.AT1G72550.1

PTM databases

iPTMnetiQ9SGE9

Proteomic databases

PaxDbiQ9SGE9
PRIDEiQ9SGE9

Genome annotation databases

EnsemblPlantsiAT1G72550.1; AT1G72550.1; AT1G72550 [Q9SGE9-1]
GeneIDi843587
GrameneiAT1G72550.1; AT1G72550.1; AT1G72550 [Q9SGE9-1]
KEGGiath:AT1G72550

Organism-specific databases

AraportiAT1G72550
TAIRilocus:2030290 AT1G72550

Phylogenomic databases

eggNOGiKOG2472 Eukaryota
COG0072 LUCA
HOGENOMiHOG000105095
InParanoidiQ9SGE9
KOiK01890
OMAiTIGVKRD
OrthoDBi378921at2759
PhylomeDBiQ9SGE9

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9SGE9

Gene expression databases

ExpressionAtlasiQ9SGE9 baseline and differential
GenevisibleiQ9SGE9 AT

Family and domain databases

CDDicd00769 PheRS_beta_core, 1 hit
Gene3Di3.50.40.10, 1 hit
InterProiView protein in InterPro
IPR005146 B3/B4_tRNA-bd
IPR009061 DNA-bd_dom_put_sf
IPR004531 Phe-tRNA-synth_IIc_bsu_arc
IPR020825 Phe-tRNA_synthase_B3/B4
IPR041616 PheRS_beta_core
IPR040659 PhetRS_B1
IPR005147 tRNA_synthase_B5-dom
PfamiView protein in Pfam
PF03483 B3_4, 1 hit
PF03484 B5, 1 hit
PF18262 PhetRS_B1, 1 hit
PF17759 tRNA_synthFbeta, 1 hit
SMARTiView protein in SMART
SM00873 B3_4, 1 hit
SM00874 B5, 1 hit
SUPFAMiSSF46955 SSF46955, 2 hits
TIGRFAMsiTIGR00471 pheT_arch, 1 hit
PROSITEiView protein in PROSITE
PS51483 B5, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYFB_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SGE9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: May 1, 2000
Last modified: October 16, 2019
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  3. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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