UniProtKB - Q9SEP4 (CHSY_ARAAL)
Protein
Chalcone synthase
Gene
CHS
Organism
Arabis alpina (Alpine rock-cress)
Status
Functioni
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
Catalytic activityi
- 4-coumaroyl-CoA + 2 H+ + 3 malonyl-CoA = 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoAPROSITE-ProRule annotationEC:2.3.1.74PROSITE-ProRule annotation
: flavonoid biosynthesis Pathwayi
This protein is involved in the pathway flavonoid biosynthesis, which is part of Secondary metabolite biosynthesis.View all proteins of this organism that are known to be involved in the pathway flavonoid biosynthesis and in Secondary metabolite biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 165 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- naringenin-chalcone synthase activity Source: UniProtKB-EC
GO - Biological processi
- flavonoid biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Flavonoid biosynthesis |
Enzyme and pathway databases
UniPathwayi | UPA00154 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:CHS |
Organismi | Arabis alpina (Alpine rock-cress) |
Taxonomic identifieri | 50452 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Arabideae › Arabis |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000215953 | 1 – 391 | Chalcone synthaseAdd BLAST | 391 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG502S4A6, Eukaryota |
Family and domain databases
Gene3Di | 3.40.47.10, 2 hits |
InterProi | View protein in InterPro IPR012328, Chalcone/stilbene_synt_C IPR001099, Chalcone/stilbene_synt_N IPR018088, Chalcone/stilbene_synthase_AS IPR011141, Polyketide_synthase_type-III IPR016039, Thiolase-like |
PANTHERi | PTHR11877, PTHR11877, 1 hit |
Pfami | View protein in Pfam PF02797, Chal_sti_synt_C, 1 hit PF00195, Chal_sti_synt_N, 1 hit |
PIRSFi | PIRSF000451, PKS_III, 1 hit |
SUPFAMi | SSF53901, SSF53901, 2 hits |
PROSITEi | View protein in PROSITE PS00441, CHALCONE_SYNTH, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9SEP4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPSLEEIRK AQRADGPAGI LGIGTANPPN HVLQAEYPDY YFRITNSDHM
60 70 80 90 100
TDLKEKFKRM CDKSMIRKRH MHLTEEFLKE NPKMCAYMAP SLDTRQDIVV
110 120 130 140 150
VEVPKLGKEA AVKAIKEWGQ PKSKITHVVF CTTSGVDMPG ADYQLTKLLG
160 170 180 190 200
LRPSVKRLMM YQQGCFAGGT VLRLAKDLAE NNRGARVLVV CSEITAVTFR
210 220 230 240 250
GPSDTHLDSL VGQALFSDGA AALIVGSDPD TSVGEKPIFE MVSAAQTILP
260 270 280 290 300
DSDGAIDGHL REVGLTFHLL KDVPGLISKN IEKSLDEAFK PLGISDWNSL
310 320 330 340 350
FWIAHPGGPA ILDQVEIKLG LKAEKMRATR HVLSEYGNMS SACVLFILDE
360 370 380 390
MRKKSAKDGA ATTGEGLEWG VLFGFGPGLT VETVVLHSVP L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF112083 Genomic DNA Translation: AAF23558.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF112083 Genomic DNA Translation: AAF23558.1 |
3D structure databases
SMRi | Q9SEP4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 50452.A0A087G6X7 |
Phylogenomic databases
eggNOGi | ENOG502S4A6, Eukaryota |
Enzyme and pathway databases
UniPathwayi | UPA00154 |
Family and domain databases
Gene3Di | 3.40.47.10, 2 hits |
InterProi | View protein in InterPro IPR012328, Chalcone/stilbene_synt_C IPR001099, Chalcone/stilbene_synt_N IPR018088, Chalcone/stilbene_synthase_AS IPR011141, Polyketide_synthase_type-III IPR016039, Thiolase-like |
PANTHERi | PTHR11877, PTHR11877, 1 hit |
Pfami | View protein in Pfam PF02797, Chal_sti_synt_C, 1 hit PF00195, Chal_sti_synt_N, 1 hit |
PIRSFi | PIRSF000451, PKS_III, 1 hit |
SUPFAMi | SSF53901, SSF53901, 2 hits |
PROSITEi | View protein in PROSITE PS00441, CHALCONE_SYNTH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CHSY_ARAAL | |
Accessioni | Q9SEP4Primary (citable) accession number: Q9SEP4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 25, 2003 |
Last sequence update: | May 1, 2000 | |
Last modified: | April 7, 2021 | |
This is version 79 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families