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Entry version 128 (07 Oct 2020)
Sequence version 3 (31 May 2011)
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Protein

Zinc finger CCCH domain-containing protein 44

Gene

At3g51120

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri110 – 176PHD-typePROSITE-ProRule annotationAdd BLAST67
Zinc fingeri1267 – 1292C3H1-typePROSITE-ProRule annotationAdd BLAST26

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger CCCH domain-containing protein 44
Short name:
AtC3H44
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At3g51120
ORF Names:F24M12.160
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G51120

The Arabidopsis Information Resource

More...
TAIRi
locus:2080863, AT3G51120

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003719981 – 1292Zinc finger CCCH domain-containing protein 44Add BLAST1292

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9SD34

PRoteomics IDEntifications database

More...
PRIDEi
Q9SD34

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
240496

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SD34, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9SD34, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT3G51120.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9SD34

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini313 – 396SWIB/MDM2PROSITE-ProRule annotationAdd BLAST84
Domaini453 – 586Plus3PROSITE-ProRule annotationAdd BLAST134
Domaini716 – 770GYFPROSITE-ProRule annotationAdd BLAST55

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi98 – 103Poly-Pro6
Compositional biasi969 – 975Poly-Thr7
Compositional biasi1145 – 1150Poly-Pro6

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri110 – 176PHD-typePROSITE-ProRule annotationAdd BLAST67
Zinc fingeri1267 – 1292C3H1-typePROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1081, Eukaryota
KOG1862, Eukaryota
KOG1946, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002000_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9SD34

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00072, GYF, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.245.10, 1 hit
2.170.260.30, 1 hit
3.30.1490.40, 1 hit
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003169, GYF
IPR035445, GYF-like_dom_sf
IPR004343, Plus-3_dom
IPR036128, Plus3-like_sf
IPR019835, SWIB_domain
IPR036885, SWIB_MDM2_dom_sf
IPR003121, SWIB_MDM2_domain
IPR019786, Zinc_finger_PHD-type_CS
IPR000571, Znf_CCCH
IPR036855, Znf_CCCH_sf
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02213, GYF, 1 hit
PF03126, Plus-3, 1 hit
PF02201, SWIB, 1 hit
PF00642, zf-CCCH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00444, GYF, 1 hit
SM00249, PHD, 1 hit
SM00719, Plus3, 1 hit
SM00151, SWIB, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF159042, SSF159042, 1 hit
SSF47592, SSF47592, 1 hit
SSF55277, SSF55277, 1 hit
SSF57903, SSF57903, 1 hit
SSF90229, SSF90229, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50829, GYF, 1 hit
PS51360, PLUS3, 1 hit
PS51925, SWIB_MDM2, 1 hit
PS50103, ZF_C3H1, 1 hit
PS01359, ZF_PHD_1, 1 hit
PS50016, ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9SD34-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENQQKQLQQ GVPELASLAG REESSVRGID LMRVDQCEEI GVNQVPALSV
60 70 80 90 100
PASTVAGAVA VPMSNEQEVK VIDEAAPIKR KRGRPPRAQA NTPLHIRPPP
110 120 130 140 150
PPPKKEDKEE DVCFICFDGG DLVLCDRRNC PKAYHPACIK RDEAFFRTTA
160 170 180 190 200
KWNCGWHICG TCQKASSYMC YTCTFSVCKR CIKDADYVIV RGNMGLCGTC
210 220 230 240 250
IKPIMLIENI AQGDNEAVKV DFDDKLSWEY LFKVYWLCLK EELSLTVDEL
260 270 280 290 300
TRANNPWKEV PNTAPKVESQ NDHTNNRALD VAVNGTKRRR TSDSPTLPNK
310 320 330 340 350
LDGKNPSNIL KKAPGDTSWA TKELLEFVSF MKNGDTSVLS QFDVQGLLLD
360 370 380 390 400
YIKKKNLRDP LQKSQVLCDQ MLVKLFGKQR VGHFEMLKLL ESHVLIQEKP
410 420 430 440 450
KGAKTTNGET THAVPSQIEE DSVHDPMVRD RRRKMRRKTD GRVQNENLDA
460 470 480 490 500
YAAIDVHNIN LIYLRRKFLE SLLDDINKVD EKVVGTILRI KVSGSDQKLD
510 520 530 540 550
IHRLVQVVGT SKAIASYQLG AKTTDVMLEI LNLDKREVIS IDQLSDQNIT
560 570 580 590 600
EDECKRLRQS IKCGLNKRLT VVDILKTAAT LQAMRINEAL EAEILKLNHL
610 620 630 640 650
RDRAKKLELL KSPEERQRLL QEVPEVHTDP SMDPSHALSE DAGLGTRKQD
660 670 680 690 700
NHVKAQSKGP QNKGVNLNNV GNNVQKKYDA PILRSRNNVH ADKDDCSKVH
710 720 730 740 750
NNSSNIQETG KDDEESEIWH YRDPTGKTQG PFSMVQLRRW KSSGHFPPYL
760 770 780 790 800
RIWRAHENQD ESVLLTDALA GRFDKATTLP SSSSLPQELK PSPHDSGRTG
810 820 830 840 850
ADVNCLQKNQ MPVNTSATSS SSSTVTAHSN DPKEKQVVAL VACSGKVEDG
860 870 880 890 900
NSVRPQPQVS CPASISVVPG HVVTPDVRET PGTDQYNTVR ADGNHNTTKT
910 920 930 940 950
LEDETNGGSV SINGSVHAPN LNQESHFLDF PSPTPKSSPE DLEAQAAETI
960 970 980 990 1000
QSLSSCVLVK GPSGVTWSTT TTSTTDAATT TSSVVVTGGQ LPQVIQQNTV
1010 1020 1030 1040 1050
VLAAPSVKPI ELAADHATAT QTSDNTQVAQ ASGWPAIVAD PDECDESVSD
1060 1070 1080 1090 1100
LLAEVEAMEQ NGLPSSPTST FHCDDDDDLK GPEKDFFNPV ARMSLTPETC
1110 1120 1130 1140 1150
RLDVSQTSIL DNVSAGKSSM LTEAKDNTPF SHCGTAGPEL LLFAPPPPPP
1160 1170 1180 1190 1200
TAISHDLTLT TTALRLGSET TVEAGTVERL PKSVLGVSSE PSPRSLSSHD
1210 1220 1230 1240 1250
SSSARGSTER SPRVSQPKRS SGHSRDRQWL NNGHNSSFNN SHNNRQWPYS
1260 1270 1280 1290
NSHGYDHGSG SYAAHPPKGL KICKFYESGY CKRGASCSFW HP
Length:1,292
Mass (Da):142,092
Last modified:May 31, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4CCA51445844BDBE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2H1ZEK0A0A2H1ZEK0_ARATH
Zinc finger CCCH domain-containing ...
At3g51120
1,305Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB62634 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL132980 Genomic DNA Translation: CAB62634.1 Sequence problems.
CP002686 Genomic DNA No translation available.

Protein sequence database of the Protein Information Resource

More...
PIRi
T45743

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132980 Genomic DNA Translation: CAB62634.1 Sequence problems.
CP002686 Genomic DNA No translation available.
PIRiT45743

3D structure databases

SMRiQ9SD34
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G51120.1

Proteomic databases

PaxDbiQ9SD34
PRIDEiQ9SD34
ProteomicsDBi240496

Organism-specific databases

AraportiAT3G51120
TAIRilocus:2080863, AT3G51120

Phylogenomic databases

eggNOGiKOG1081, Eukaryota
KOG1862, Eukaryota
KOG1946, Eukaryota
HOGENOMiCLU_002000_1_0_1
InParanoidiQ9SD34

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9SD34

Gene expression databases

ExpressionAtlasiQ9SD34, baseline and differential
GenevisibleiQ9SD34, AT

Family and domain databases

CDDicd00072, GYF, 1 hit
Gene3Di1.10.245.10, 1 hit
2.170.260.30, 1 hit
3.30.1490.40, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR003169, GYF
IPR035445, GYF-like_dom_sf
IPR004343, Plus-3_dom
IPR036128, Plus3-like_sf
IPR019835, SWIB_domain
IPR036885, SWIB_MDM2_dom_sf
IPR003121, SWIB_MDM2_domain
IPR019786, Zinc_finger_PHD-type_CS
IPR000571, Znf_CCCH
IPR036855, Znf_CCCH_sf
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF02213, GYF, 1 hit
PF03126, Plus-3, 1 hit
PF02201, SWIB, 1 hit
PF00642, zf-CCCH, 1 hit
SMARTiView protein in SMART
SM00444, GYF, 1 hit
SM00249, PHD, 1 hit
SM00719, Plus3, 1 hit
SM00151, SWIB, 1 hit
SUPFAMiSSF159042, SSF159042, 1 hit
SSF47592, SSF47592, 1 hit
SSF55277, SSF55277, 1 hit
SSF57903, SSF57903, 1 hit
SSF90229, SSF90229, 1 hit
PROSITEiView protein in PROSITE
PS50829, GYF, 1 hit
PS51360, PLUS3, 1 hit
PS51925, SWIB_MDM2, 1 hit
PS50103, ZF_C3H1, 1 hit
PS01359, ZF_PHD_1, 1 hit
PS50016, ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC3H44_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SD34
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 31, 2011
Last modified: October 7, 2020
This is version 128 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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