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Entry version 152 (02 Jun 2021)
Sequence version 1 (01 May 2000)
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Protein

Cell division control protein 48 homolog D

Gene

CDC48D

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity).

By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi249 – 256ATPSequence analysis8
Nucleotide bindingi522 – 529ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, Protein transport, Transport
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cell division control protein 48 homolog D
Short name:
AtCDC48d
Alternative name(s):
Transitional endoplasmic reticulum ATPase D
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDC48D
Ordered Locus Names:At3g53230
ORF Names:T4D2.160
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G53230

The Arabidopsis Information Resource

More...
TAIRi
locus:2101933, AT3G53230

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000845822 – 815Cell division control protein 48 homolog DAdd BLAST814

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1
Modified residuei42PhosphoserineBy similarity1
Modified residuei720PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9SCN8

PRoteomics IDEntifications database

More...
PRIDEi
Q9SCN8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
223921

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9SCN8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9SCN8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9SCN8, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
9806, 3 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT3G53230.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9SCN8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni772 – 815DisorderedSequence analysisAdd BLAST44

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the AAA ATPase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0730, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000688_12_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9SCN8

Identification of Orthologs from Complete Genome Data

More...
OMAi
IANECQT

Database of Orthologous Groups

More...
OrthoDBi
194195at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9SCN8

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR005938, AAA_ATPase_CDC48
IPR041569, AAA_lid_3
IPR009010, Asp_de-COase-like_dom_sf
IPR003959, ATPase_AAA_core
IPR003960, ATPase_AAA_CS
IPR004201, Cdc48_dom2
IPR029067, CDC48_domain_2-like_sf
IPR003338, CDC4_N-term_subdom
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00004, AAA, 2 hits
PF17862, AAA_lid_3, 2 hits
PF02933, CDC48_2, 1 hit
PF02359, CDC48_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits
SM01072, CDC48_2, 1 hit
SM01073, CDC48_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50692, SSF50692, 1 hit
SSF52540, SSF52540, 2 hits
SSF54585, SSF54585, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01243, CDC48, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00674, AAA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9SCN8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANQAESSDS KGTKKDFSTA ILEKKKAANR LVVDEAINDD NSVVSLHPDT
60 70 80 90 100
MEKLQLFRGD TILIKGKKRK DTVCIALADE TCDEPKIRMN KVVRSNLRVR
110 120 130 140 150
LGDVISVHQC PDVKYGNRVH ILPLDDTIEG VSGNIFDAYL KPYFLEAYRP
160 170 180 190 200
VRKGDLFLVR GGMRSIEFKV IETDPAEYCV VAPDTEIFCE GEPIKREDEE
210 220 230 240 250
RLDEVGYDDV GGVRKQMAQI RELVELPLRH PQLFKSIGVK PPKGILLYGP
260 270 280 290 300
PGSGKTLIAR AVANETGAFF FCINGPEIMS KLAGESESNL RKAFEEAEKN
310 320 330 340 350
APSIIFIDEI DSIAPKREKT HGEVERRIVS QLLTLMDGLK SRAHVIVMGA
360 370 380 390 400
TNRPNSIDPA LRRFGRFDRE IDIGVPDEIG RLEVLRIHTK NMKLAEDVDL
410 420 430 440 450
ERVSKDTHGY VGADLAALCT EAALQCIREK MDVIDLDDEE IDAEILNSMA
460 470 480 490 500
VSNDHFQTAL GNSNPSALRE TVVEVPNVSW EDIGGLENVK RELQETVQYP
510 520 530 540 550
VEHPEKFEKF GMSPSKGVLF YGPPGCGKTL LAKAIANECQ ANFISIKGPE
560 570 580 590 600
LLTMWFGESE ANVREIFDKA RQSAPCVLFF DELDSIATQR GNSVGDAGGA
610 620 630 640 650
ADRVLNQLLT EMDGMNAKKT VFIIGATNRP DIIDPALLRP GRLDQLIYIP
660 670 680 690 700
LPDEESRYQI FKSCLRKSPV AKDVDLRALA KYTQGFSGAD ITEICQRSCK
710 720 730 740 750
YAIRENIEKD IEKERKRAES PEAMEEDEEE IAEIKAGHFE ESMKYARRSV
760 770 780 790 800
SDADIRKYQA FAQTLQQSRG FGSEFRFPDA PTGTTGAFPG AAATVGGVDP
810
FATSGGAADD DDLYS
Length:815
Mass (Da):90,340
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8F2817396748B6CC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8B1Y1A0A1P8B1Y1_ARATH
Cell division cycle 48B
CDC48B cell division cycle 48B, At2g03670, F19B11.12, F19B11_12, T4D2.160
430Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL132958 Genomic DNA Translation: CAB64226.1
CP002686 Genomic DNA Translation: AEE79050.1
AK228801 mRNA Translation: BAF00697.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T46169

NCBI Reference Sequences

More...
RefSeqi
NP_190891.1, NM_115183.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G53230.1; AT3G53230.1; AT3G53230

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
824489

Gramene; a comparative resource for plants

More...
Gramenei
AT3G53230.1; AT3G53230.1; AT3G53230

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G53230

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132958 Genomic DNA Translation: CAB64226.1
CP002686 Genomic DNA Translation: AEE79050.1
AK228801 mRNA Translation: BAF00697.1
PIRiT46169
RefSeqiNP_190891.1, NM_115183.4

3D structure databases

SMRiQ9SCN8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi9806, 3 interactors
STRINGi3702.AT3G53230.1

PTM databases

iPTMnetiQ9SCN8

Proteomic databases

PaxDbiQ9SCN8
PRIDEiQ9SCN8
ProteomicsDBi223921

Genome annotation databases

EnsemblPlantsiAT3G53230.1; AT3G53230.1; AT3G53230
GeneIDi824489
GrameneiAT3G53230.1; AT3G53230.1; AT3G53230
KEGGiath:AT3G53230

Organism-specific databases

AraportiAT3G53230
TAIRilocus:2101933, AT3G53230

Phylogenomic databases

eggNOGiKOG0730, Eukaryota
HOGENOMiCLU_000688_12_0_1
InParanoidiQ9SCN8
OMAiIANECQT
OrthoDBi194195at2759
PhylomeDBiQ9SCN8

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9SCN8

Gene expression databases

ExpressionAtlasiQ9SCN8, baseline and differential
GenevisibleiQ9SCN8, AT

Family and domain databases

InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR005938, AAA_ATPase_CDC48
IPR041569, AAA_lid_3
IPR009010, Asp_de-COase-like_dom_sf
IPR003959, ATPase_AAA_core
IPR003960, ATPase_AAA_CS
IPR004201, Cdc48_dom2
IPR029067, CDC48_domain_2-like_sf
IPR003338, CDC4_N-term_subdom
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00004, AAA, 2 hits
PF17862, AAA_lid_3, 2 hits
PF02933, CDC48_2, 1 hit
PF02359, CDC48_N, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SM01072, CDC48_2, 1 hit
SM01073, CDC48_N, 1 hit
SUPFAMiSSF50692, SSF50692, 1 hit
SSF52540, SSF52540, 2 hits
SSF54585, SSF54585, 1 hit
TIGRFAMsiTIGR01243, CDC48, 1 hit
PROSITEiView protein in PROSITE
PS00674, AAA, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCD48D_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SCN8
Secondary accession number(s): Q0WQA2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: May 1, 2000
Last modified: June 2, 2021
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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