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UniProtKB - Q9SAK4 (SSDH_ARATH)

Entry version 140 (07 Apr 2021)
Sequence version 2 (31 Oct 2006)
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Protein

Succinate-semialdehyde dehydrogenase, mitochondrial

Gene

ALDH5F1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Oxidizes specifically succinate semialdehyde. Involved in plant response to environmental stress by preventing the accumulation of reactive oxygen species, probably by regulating proline, gamma-hydroxybutyrate (GHB) and gamma-aminobutyrate (GABA) levels (PubMed:15642352).

Required for the maintenance of the shoot apical meristem (SAM) structure and subsequent adaxial-abaxial axis-dependent development of cotyledons and leaves (PubMed:21690177, PubMed:25840087).

5 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Competitive inhibition by NADH. Inhibited by ATP, ADP and AMP. Redox-regulated. Inhibited under oxydizing conditions (By similarity).By similarity

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=130 µM for NAD+ (at 24 degrees Celsius)1 Publication

    pH dependencei

    Optimum pH is 9-9.5.1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: 4-aminobutanoate degradation

    This protein is involved in the pathway 4-aminobutanoate degradation, which is part of Amino-acid degradation.1 Publication
    View all proteins of this organism that are known to be involved in the pathway 4-aminobutanoate degradation and in Amino-acid degradation.

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei199Transition state stabilizerBy similarity1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei207SubstrateBy similarity1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei297Proton acceptorPROSITE-ProRule annotation1
    Binding sitei297NADBy similarity1
    Binding sitei325SubstrateBy similarity1
    Active sitei331NucleophilePROSITE-ProRule annotation1
    Binding sitei488SubstrateBy similarity1

    Regions

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi196 – 198NADBy similarity3
    Nucleotide bindingi222 – 225NADBy similarity4
    Nucleotide bindingi275 – 280NADBy similarity6
    Nucleotide bindingi428 – 430NADBy similarity3

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    Complete GO annotation on QuickGO ...

    GO - Biological processi

    Complete GO annotation on QuickGO ...

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionOxidoreductase
    LigandNAD

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...    BioCyci    		ARA:AT1G79440-MONOMER

    BRENDA Comprehensive Enzyme Information System

    More...    BRENDAi    		1.2.1.24, 399

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...    UniPathwayi    		UPA00733

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Succinate-semialdehyde dehydrogenase, mitochondrial1 Publication (EC:1.2.1.241 Publication)
    Short name:
    At-SSADH11 Publication
    Alternative name(s):
    Aldehyde dehydrogenase family 5 member F12 Publications
    NAD(+)-dependent succinic semialdehyde dehydrogenase1 Publication
    Protein ENLARGED FIL EXPRESSING DOMAIN 12 Publications
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:ALDH5F12 Publications
    Synonyms:ENF12 Publications, SSADH11 Publication
    Ordered Locus Names:At1g79440Imported
    ORF Names:T8K14.14Imported
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

    Organism-specific databases

    Arabidopsis Information Portal

    More...    Araporti    		AT1G79440

    The Arabidopsis Information Resource

    More...    TAIRi    		locus:2206405, AT1G79440

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Keywords - Cellular componenti

    Mitochondrion

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    <p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

    Plants are sensitive to UVB and heat stress, and accumulate elevated levels of H2O2 (PubMed:12740438). High light-dependent increased of proline, gamma-hydroxybutyrate (GHB) and gamma-aminobutyrate (GABA) levels. Treatment with gamma-vinyl-gamma-aminobutyrate, a specific gamma-aminobutyrate (GABA)-transaminase inhibitor, prevents the accumulation of reactive oxygen intermediates (ROI) and GHB in ssadh mutants, inhibits cell death, and improves growth (PubMed:15642352). The ssadh mutant defects associated with stress responses are suppressed by POP2 disruption (PubMed:18846220). In enf1, pleiotropic developmental defects including dwarfism, and abnormal leaf shape (including abaxialized and adaxialized leaves) and cotyledon associated with altered GABA and SucA levels in shoots; these phenotypes are partially suppressed by the disruption of POP2/GABAT1, GSA1, GSA2 and HEMA1 (PubMed:21690177, PubMed:25840087). Abnormal FIL expression, especially in the adaxial side, in the leaf primordia (PubMed:21690177).5 Publications

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 34MitochondrionSequence analysisAdd BLAST34
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025606435 – 528Succinate-semialdehyde dehydrogenase, mitochondrialAdd BLAST494

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi331 ↔ 333In inhibited formBy similarity

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...    PaxDbi    		Q9SAK4

    PRoteomics IDEntifications database

    More...    PRIDEi    		Q9SAK4

    ProteomicsDB: a multi-organism proteome resource

    More...    ProteomicsDBi    		232490

    PTM databases

    MetOSite database of methionine sulfoxide sites

    More...    MetOSitei    		Q9SAK4

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed in developing leaf tissues.1 Publication

    <p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    Induced during cold (4 degrees Celsius) acclimation (PubMed:17461790). Induced by salt (NaCl) (PubMed:20122158).2 Publications

    Gene expression databases

    ExpressionAtlas, Differential and Baseline Expression

    More...    ExpressionAtlasi    		Q9SAK4, baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...    Genevisiblei    		Q9SAK4, AT

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Homotetramer.

    1 Publication

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...    STRINGi    		3702.AT1G79440.1

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...    SMRi    		Q9SAK4

    Database of comparative protein structure models

    More...    ModBasei    		Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...    eggNOGi    		KOG2451, Eukaryota

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...    HOGENOMi    		CLU_005391_5_0_1

    InParanoid: Eukaryotic Ortholog Groups

    More...    InParanoidi    		Q9SAK4

    Identification of Orthologs from Complete Genome Data

    More...    OMAi    		WHKLIEQ

    Database of Orthologous Groups

    More...    OrthoDBi    		899961at2759

    Database for complete collections of gene phylogenies

    More...    PhylomeDBi    		Q9SAK4

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...    Gene3Di    		3.40.309.10, 1 hit
    3.40.605.10, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...    InterProi    		View protein in InterPro
    IPR016161, Ald_DH/histidinol_DH
    IPR016163, Ald_DH_C
    IPR016160, Ald_DH_CS_CYS
    IPR029510, Ald_DH_CS_GLU
    IPR016162, Ald_DH_N
    IPR015590, Aldehyde_DH_dom
    IPR010102, Succ_semiAld_DH

    Pfam protein domain database

    More...    Pfami    		View protein in Pfam
    PF00171, Aldedh, 1 hit

    Superfamily database of structural and functional annotation

    More...    SUPFAMi    		SSF53720, SSF53720, 1 hit

    TIGRFAMs; a protein family database

    More...    TIGRFAMsi    		TIGR01780, SSADH, 1 hit

    PROSITE; a protein domain and family database

    More...    PROSITEi    		View protein in PROSITE
    PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit
    PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9SAK4-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MVIGAAARVA IGGCRKLISS HTSLLLVSSQ CRQMSMDAQS VSEKLRSSGL 
            60         70         80         90        100
    LRTQGLIGGK WLDSYDNKTI KVNNPATGEI IADVACMGTK ETNDAIASSY 
           110        120        130        140        150
    EAFTSWSRLT AGERSKVLRR WYDLLIAHKE ELGQLITLEQ GKPLKEAIGE 
           160        170        180        190        200
    VAYGASFIEY YAEEAKRVYG DIIPPNLSDR RLLVLKQPVG VVGAITPWNF 
           210        220        230        240        250
    PLAMITRKVG PALASGCTVV VKPSELTPLT ALAAAELALQ AGVPPGALNV 
           260        270        280        290        300
    VMGNAPEIGD ALLTSPQVRK ITFTGSTAVG KKLMAAAAPT VKKVSLELGG 
           310        320        330        340        350
    NAPSIVFDDA DLDVAVKGTL AAKFRNSGQT CVCANRVLVQ DGIYDKFAEA 
           360        370        380        390        400
    FSEAVQKLEV GDGFRDGTTQ GPLINDAAVQ KVETFVQDAV SKGAKIIIGG 
           410        420        430        440        450
    KRHSLGMTFY EPTVIRDVSD NMIMSKEEIF GPVAPLIRFK TEEDAIRIAN 
           460        470        480        490        500
    DTIAGLAAYI FTNSVQRSWR VFEALEYGLV GVNEGLISTE VAPFGGVKQS 
           510        520 
    GLGREGSKYG MDEYLEIKYV CLGDMNRH
    Length:528
    Mass (Da):56,559
    Last modified:October 31, 2006 - v2
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA0DA95A3A592B5B9
    GO

    <p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence AAD30232 differs from that shown. Reason: Erroneous gene model prediction.Curated

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...    EMBLi

    GenBank nucleotide sequence database

    More...    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...    DDBJi
    Links Updated
    		AF117335 mRNA Translation: AAF23590.1
    AC007202 Genomic DNA Translation: AAD30232.1 Sequence problems.
    CP002684 Genomic DNA Translation: AEE36243.1
    AF428367 mRNA Translation: AAL16297.1
    AY056147 mRNA Translation: AAL07226.1

    Protein sequence database of the Protein Information Resource

    More...    PIRi    		E96825

    NCBI Reference Sequences

    More...    RefSeqi    		NP_178062.1, NM_106592.5

    Genome annotation databases

    Ensembl plant genome annotation project

    More...    EnsemblPlantsi    		AT1G79440.1; AT1G79440.1; AT1G79440

    Database of genes from NCBI RefSeq genomes

    More...    GeneIDi    		844282

    Gramene; a comparative resource for plants

    More...    Gramenei    		AT1G79440.1; AT1G79440.1; AT1G79440

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...    KEGGi    		ath:AT1G79440

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    		AF117335 mRNA Translation: AAF23590.1
    AC007202 Genomic DNA Translation: AAD30232.1 Sequence problems.
    CP002684 Genomic DNA Translation: AEE36243.1
    AF428367 mRNA Translation: AAL16297.1
    AY056147 mRNA Translation: AAL07226.1
    PIRiE96825
    RefSeqiNP_178062.1, NM_106592.5

    3D structure databases

    SMRiQ9SAK4
    ModBaseiSearch...

    Protein-protein interaction databases

    STRINGi3702.AT1G79440.1

    PTM databases

    MetOSiteiQ9SAK4

    Proteomic databases

    PaxDbiQ9SAK4
    PRIDEiQ9SAK4
    ProteomicsDBi232490

    Genome annotation databases

    EnsemblPlantsiAT1G79440.1; AT1G79440.1; AT1G79440
    GeneIDi844282
    GrameneiAT1G79440.1; AT1G79440.1; AT1G79440
    KEGGiath:AT1G79440

    Organism-specific databases

    AraportiAT1G79440
    TAIRilocus:2206405, AT1G79440

    Phylogenomic databases

    eggNOGiKOG2451, Eukaryota
    HOGENOMiCLU_005391_5_0_1
    InParanoidiQ9SAK4
    OMAiWHKLIEQ
    OrthoDBi899961at2759
    PhylomeDBiQ9SAK4

    Enzyme and pathway databases

    UniPathwayiUPA00733
    BioCyciARA:AT1G79440-MONOMER
    BRENDAi1.2.1.24, 399

    Miscellaneous databases

    Protein Ontology

    More...    PROi    		PR:Q9SAK4

    Gene expression databases

    ExpressionAtlasiQ9SAK4, baseline and differential
    GenevisibleiQ9SAK4, AT

    Family and domain databases

    Gene3Di3.40.309.10, 1 hit
    3.40.605.10, 1 hit
    InterProiView protein in InterPro
    IPR016161, Ald_DH/histidinol_DH
    IPR016163, Ald_DH_C
    IPR016160, Ald_DH_CS_CYS
    IPR029510, Ald_DH_CS_GLU
    IPR016162, Ald_DH_N
    IPR015590, Aldehyde_DH_dom
    IPR010102, Succ_semiAld_DH
    PfamiView protein in Pfam
    PF00171, Aldedh, 1 hit
    SUPFAMiSSF53720, SSF53720, 1 hit
    TIGRFAMsiTIGR01780, SSADH, 1 hit
    PROSITEiView protein in PROSITE
    PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit
    PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit

    MobiDB: a database of protein disorder and mobility annotations

    More...    MobiDBi    		Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSSDH_ARATH
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9SAK4
    Secondary accession number(s): Q9SEK4
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: October 31, 2006
    Last modified: April 7, 2021
    This is version 140 of the entry and version 2 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families
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