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Entry version 118 (02 Jun 2021)
Sequence version 1 (01 May 2000)
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Protein

Pentatricopeptide repeat-containing protein At1g74850, chloroplastic

Gene

PTAC2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in plastid gene expression.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Pentatricopeptide repeat-containing protein At1g74850, chloroplastic
Alternative name(s):
Protein PLASTID TRANSCRIPTIONALLY ACTIVE 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PTAC2
Ordered Locus Names:At1g74850
ORF Names:F25A4.18, F9E10.30
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G74850

The Arabidopsis Information Resource

More...
TAIRi
locus:2027166, AT1G74850

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Chloroplast, Plastid

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Lethal without exogenous carbon sources. Decrease of total chlorophyll content as well as a decrease in the chlorophyll a:b ratio. Unequally expanded grana thylakoids. Altered expression profiles of plastid genes.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 66ChloroplastSequence analysisAdd BLAST66
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000034286567 – 862Pentatricopeptide repeat-containing protein At1g74850, chloroplasticAdd BLAST796

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9S7Q2

PRoteomics IDEntifications database

More...
PRIDEi
Q9S7Q2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
250580

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mostly expressed in leaves, stems and flowers, but barely in roots.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9S7Q2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9S7Q2, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9S7Q2, 1 interactor

Molecular INTeraction database

More...
MINTi
Q9S7Q2

STRING: functional protein association networks

More...
STRINGi
3702.AT1G74850.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9S7Q2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati104 – 139PPR 1Add BLAST36
Repeati140 – 174PPR 2Add BLAST35
Repeati175 – 209PPR 3Add BLAST35
Repeati210 – 245PPR 4Add BLAST36
Repeati246 – 280PPR 5Add BLAST35
Repeati281 – 315PPR 6Add BLAST35
Repeati316 – 350PPR 7Add BLAST35
Repeati351 – 385PPR 8Add BLAST35
Repeati386 – 420PPR 9Add BLAST35
Repeati421 – 455PPR 10Add BLAST35
Repeati456 – 490PPR 11Add BLAST35
Repeati491 – 525PPR 12Add BLAST35
Repeati526 – 560PPR 13Add BLAST35
Repeati561 – 595PPR 14Add BLAST35
Repeati596 – 630PPR 15Add BLAST35
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini713 – 801SmrPROSITE-ProRule annotationAdd BLAST89

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni831 – 862DisorderedSequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi831 – 847Polar residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PPR family. P subfamily.Curated

Keywords - Domaini

Repeat, Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4197, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002706_49_5_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9S7Q2

Identification of Orthologs from Complete Genome Data

More...
OMAi
DIDTCEN

Database of Orthologous Groups

More...
OrthoDBi
1344243at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9S7Q2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002885, Pentatricopeptide_repeat
IPR002625, Smr_dom
IPR011990, TPR-like_helical_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01535, PPR, 2 hits
PF13041, PPR_2, 2 hits
PF13812, PPR_3, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00463, SMR, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00756, PPR, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51375, PPR, 16 hits
PS50828, SMR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9S7Q2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLAIPNPNS HHLSFLIQNS SFIGNRRFAD GNRLRFLSGG NRKPCSFSGK
60 70 80 90 100
IKAKTKDLVL GNPSVSVEKG KYSYDVESLI NKLSSLPPRG SIARCLDIFK
110 120 130 140 150
NKLSLNDFAL VFKEFAGRGD WQRSLRLFKY MQRQIWCKPN EHIYTIMISL
160 170 180 190 200
LGREGLLDKC LEVFDEMPSQ GVSRSVFSYT ALINAYGRNG RYETSLELLD
210 220 230 240 250
RMKNEKISPS ILTYNTVINA CARGGLDWEG LLGLFAEMRH EGIQPDIVTY
260 270 280 290 300
NTLLSACAIR GLGDEAEMVF RTMNDGGIVP DLTTYSHLVE TFGKLRRLEK
310 320 330 340 350
VCDLLGEMAS GGSLPDITSY NVLLEAYAKS GSIKEAMGVF HQMQAAGCTP
360 370 380 390 400
NANTYSVLLN LFGQSGRYDD VRQLFLEMKS SNTDPDAATY NILIEVFGEG
410 420 430 440 450
GYFKEVVTLF HDMVEENIEP DMETYEGIIF ACGKGGLHED ARKILQYMTA
460 470 480 490 500
NDIVPSSKAY TGVIEAFGQA ALYEEALVAF NTMHEVGSNP SIETFHSLLY
510 520 530 540 550
SFARGGLVKE SEAILSRLVD SGIPRNRDTF NAQIEAYKQG GKFEEAVKTY
560 570 580 590 600
VDMEKSRCDP DERTLEAVLS VYSFARLVDE CREQFEEMKA SDILPSIMCY
610 620 630 640 650
CMMLAVYGKT ERWDDVNELL EEMLSNRVSN IHQVIGQMIK GDYDDDSNWQ
660 670 680 690 700
IVEYVLDKLN SEGCGLGIRF YNALLDALWW LGQKERAARV LNEATKRGLF
710 720 730 740 750
PELFRKNKLV WSVDVHRMSE GGMYTALSVW LNDINDMLLK GDLPQLAVVV
760 770 780 790 800
SVRGQLEKSS AARESPIAKA AFSFLQDHVS SSFSFTGWNG GRIMCQRSQL
810 820 830 840 850
KQLLSTKEPT SEESENKNLV ALANSPIFAA GTRASTSSDT NHSGNPTQRR
860
TRTKKELAGS TA
Length:862
Mass (Da):96,326
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i674C8853A78751D3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC008263 Genomic DNA Translation: AAD55291.1
AC013258 Genomic DNA Translation: AAG51934.1
CP002684 Genomic DNA Translation: AEE35639.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A96778

NCBI Reference Sequences

More...
RefSeqi
NP_177623.1, NM_106143.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G74850.1; AT1G74850.1; AT1G74850

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
843824

Gramene; a comparative resource for plants

More...
Gramenei
AT1G74850.1; AT1G74850.1; AT1G74850

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G74850

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Pentatricopeptide repeat proteins

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008263 Genomic DNA Translation: AAD55291.1
AC013258 Genomic DNA Translation: AAG51934.1
CP002684 Genomic DNA Translation: AEE35639.1
PIRiA96778
RefSeqiNP_177623.1, NM_106143.3

3D structure databases

SMRiQ9S7Q2
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9S7Q2, 1 interactor
MINTiQ9S7Q2
STRINGi3702.AT1G74850.1

Proteomic databases

PaxDbiQ9S7Q2
PRIDEiQ9S7Q2
ProteomicsDBi250580

Genome annotation databases

EnsemblPlantsiAT1G74850.1; AT1G74850.1; AT1G74850
GeneIDi843824
GrameneiAT1G74850.1; AT1G74850.1; AT1G74850
KEGGiath:AT1G74850

Organism-specific databases

AraportiAT1G74850
TAIRilocus:2027166, AT1G74850

Phylogenomic databases

eggNOGiKOG4197, Eukaryota
HOGENOMiCLU_002706_49_5_1
InParanoidiQ9S7Q2
OMAiDIDTCEN
OrthoDBi1344243at2759
PhylomeDBiQ9S7Q2

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9S7Q2

Gene expression databases

ExpressionAtlasiQ9S7Q2, baseline and differential
GenevisibleiQ9S7Q2, AT

Family and domain databases

Gene3Di1.25.40.10, 5 hits
InterProiView protein in InterPro
IPR002885, Pentatricopeptide_repeat
IPR002625, Smr_dom
IPR011990, TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF01535, PPR, 2 hits
PF13041, PPR_2, 2 hits
PF13812, PPR_3, 3 hits
SMARTiView protein in SMART
SM00463, SMR, 1 hit
TIGRFAMsiTIGR00756, PPR, 11 hits
PROSITEiView protein in PROSITE
PS51375, PPR, 16 hits
PS50828, SMR, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPP124_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9S7Q2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: May 1, 2000
Last modified: June 2, 2021
This is version 118 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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