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Protein

Protein TIFY 10B

Gene

TIFY10B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY10B/JAZ2 interaction. Activated by MYC2, MYC3 and MYC4 transcription factors.2 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processJasmonic acid signaling pathway, Plant defense, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TIFY 10B
Alternative name(s):
Jasmonate ZIM domain-containing protein 2
Gene namesi
Name:TIFY10B
Synonyms:JAZ2
Ordered Locus Names:At1g74950
ORF Names:F25A4.8, F9E10.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G74950
TAIRilocus:2027267 AT1G74950

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003006531 – 249Protein TIFY 10BAdd BLAST249

Post-translational modificationi

Ubiquitinated. Targeted for degradation by the SCF(COI1) E3 ubiquitin ligase-proteasome pathway during jasmonate signaling.By similarity

Keywords - PTMi

Ubl conjugation

Proteomic databases

PaxDbiQ9S7M2
PRIDEiQ9S7M2

Expressioni

Tissue specificityi

Expressed in cotyledons, hypocotyls, roots, sepals, petal vascular tissue and stigmas of developing flowers. Expressed in stamen filaments after jasmonic acid treatment.1 Publication

Inductioni

Up-regulated by jasmonate, wounding and herbivory.2 Publications

Gene expression databases

ExpressionAtlasiQ9S7M2 baseline and differential
GenevisibleiQ9S7M2 AT

Interactioni

Subunit structurei

Homo- and heterodimer. Interacts with COI1, MYC2, MYC3, MYC4, AFPH2/NINJA, TIFY10A/JAZ1, TIFY6B/JAZ3, TIFY11A/JAZ5, TIFY11B/JAZ6, TIFY5A/JAZ8, TIFY7/JAZ9, TIFY9/JAZ10, TIFY3A/JAZ11 and TIFY3B/JAZ12.5 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi29053, 20 interactors
DIPiDIP-52214N
ELMiQ9S7M2
IntActiQ9S7M2, 16 interactors
STRINGi3702.AT1G74950.1

Structurei

3D structure databases

SMRiQ9S7M2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 148TifyPROSITE-ProRule annotationAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi87 – 95Poly-Ser9

Domaini

The jas domain (203-228) is required for interaction with COI1.By similarity

Sequence similaritiesi

Belongs to the TIFY/JAZ family.Curated

Phylogenomic databases

eggNOGiENOG410IZA3 Eukaryota
ENOG410ZDCD LUCA
HOGENOMiHOG000239787
InParanoidiQ9S7M2
KOiK13464
OMAiPCEASGM
OrthoDBiEOG09360N2V
PhylomeDBiQ9S7M2

Family and domain databases

InterProiView protein in InterPro
IPR018467 CCT_CS
IPR010399 Tify_dom
PfamiView protein in Pfam
PF09425 CCT_2, 1 hit
PF06200 tify, 1 hit
SMARTiView protein in SMART
SM00979 TIFY, 1 hit
PROSITEiView protein in PROSITE
PS51320 TIFY, 1 hit

Sequencei

Sequence statusi: Complete.

Q9S7M2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSFSAECWD FSGRKPSFSQ TCTRLSRYLK EKGSFGDLSL GMTCKPDVNG
60 70 80 90 100
GSRQPTMMNL FPCEASGMDS SAGQEDIKPK TMFPRQSSFS SSSSSGTKED
110 120 130 140 150
VQMIKETTKS VKPESQSAPL TIFYGGRVMV FDDFSAEKAK EVIDLANKGS
160 170 180 190 200
AKSFTCFTAE VNNNHSAYSQ KEIASSPNPV CSPAKTAAQE PIQPNPASLA
210 220 230 240
CELPIARRAS LHRFLEKRKD RITSKAPYQI DGSAEASSKP TNPAWLSSR
Length:249
Mass (Da):27,072
Last modified:May 1, 2000 - v1
Checksum:i7410B2A50505A543
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti31E → D in AAM64554 (Ref. 4) Curated1
Sequence conflicti195N → K in AAM64554 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008263 Genomic DNA Translation: AAD55281.1
AC013258 Genomic DNA Translation: AAG51928.1
CP002684 Genomic DNA Translation: AEE35654.1
AF344319 mRNA Translation: AAK06870.1
AF386959 mRNA Translation: AAK62404.1
BT006301 mRNA Translation: AAP13409.1
AY086993 mRNA Translation: AAM64554.1
PIRiC96779
RefSeqiNP_565096.1, NM_106153.4
UniGeneiAt.19896

Genome annotation databases

EnsemblPlantsiAT1G74950.1; AT1G74950.1; AT1G74950
GeneIDi843834
GrameneiAT1G74950.1; AT1G74950.1; AT1G74950
KEGGiath:AT1G74950

Similar proteinsi

Entry informationi

Entry nameiTI10B_ARATH
AccessioniPrimary (citable) accession number: Q9S7M2
Secondary accession number(s): Q8LBU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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