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Protein

Potassium-transporting ATPase ATP-binding subunit

Gene

kdpB

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system.UniRule annotation

Catalytic activityi

ATP + H2O + K+(Out) = ADP + phosphate + K+(In).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei3044-aspartylphosphate intermediateUniRule annotation1
Binding sitei341ATPUniRule annotation1
Binding sitei345ATPUniRule annotation1
Binding sitei389ATPUniRule annotation1
Metal bindingi512MagnesiumUniRule annotation1
Metal bindingi516MagnesiumUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi371 – 378ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
Biological processIon transport, Potassium transport, Transport
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Potassium-transporting ATPase ATP-binding subunitUniRule annotation (EC:3.6.3.12UniRule annotation)
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chainUniRule annotation
Potassium-binding and translocating subunit BUniRule annotation
Potassium-translocating ATPase B chainUniRule annotation
Gene namesi
Name:kdpBUniRule annotation
Ordered Locus Names:DR_B0083
Encoded oniPlasmid megaplasmid MP10 Publication
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Plasmid megaplasmid MP1

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei38 – 58HelicalUniRule annotationAdd BLAST21
Transmembranei67 – 87HelicalUniRule annotationAdd BLAST21
Transmembranei216 – 236HelicalUniRule annotationAdd BLAST21
Transmembranei253 – 273HelicalUniRule annotationAdd BLAST21
Transmembranei582 – 602HelicalUniRule annotationAdd BLAST21
Transmembranei610 – 630HelicalUniRule annotationAdd BLAST21
Transmembranei654 – 674HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000461141 – 675Potassium-transporting ATPase ATP-binding subunitAdd BLAST675

Keywords - PTMi

Phosphoprotein

Interactioni

Subunit structurei

The system is composed of three essential subunits: KdpA, KdpB and KdpC.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ9RZP0
SMRiQ9RZP0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000244113
InParanoidiQ9RZP0
KOiK01547
OMAiILWLWFT
OrthoDBiPOG091H00YH

Family and domain databases

CDDicd02078 P-type_ATPase_K, 1 hit
Gene3Di3.40.1110.10, 1 hit
HAMAPiMF_00285 KdpB, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR006391 P-type_ATPase_bsu_IA
IPR001757 P_typ_ATPase
PANTHERiPTHR43743 PTHR43743, 1 hit
SUPFAMiSSF56784 SSF56784, 3 hits
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 2 hits
TIGRFAMsiTIGR01494 ATPase_P-type, 2 hits
TIGR01497 kdpB, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9RZP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTAPQPKQS IFSPELVRGA VRASFAKLSP RDQARNPVMF VVYLGTALTA
60 70 80 90 100
YLTVANLVTG KPWGYELAIT LLLLLTVLFA NFAEGMAEAR GKAQAASLRS
110 120 130 140 150
AREDVKARRL VNGQEELVAG TALERGDLVV VEAGEMIPAD GEIVEGLASV
160 170 180 190 200
DESAITGESA PVIREAGTDH SGVTGGTKVL SDRIVIQITS GAGESFLDRM
210 220 230 240 250
IALVEGASRQ KTPNEIALSI LLSGLTLIFL LAVVTLYPFT VYAGAPASAV
260 270 280 290 300
TLIALLVCLI PTTIGGLLPA IGIAGMDRAL QANVIAKSGK AVEVAGDVDV
310 320 330 340 350
LLLDKTGTIT IGNRMATKFH PLPGVTEAEL AKAALLSSLA DPTPEGKSIV
360 370 380 390 400
ALARQLGVDA PEPAGAEFIE FTAQTRMSGV DFPGTSIRKG AGSRISALAQ
410 420 430 440 450
ERGGQLPPEL AAITDEVSRQ GATPLTVIEN DRLLGVVALS DIIKPGIRER
460 470 480 490 500
FEQLRRMGLR TVMITGDNPL TAEAIAKEAG VDGFLAEATP EDKMEMIKQE
510 520 530 540 550
QASGKLVAMM GDGTNDAPAL AQADVGLAMN SGTQAAKEAG NMVDLDSDPT
560 570 580 590 600
KLLEVVEIGK GLLITRGALT TFSIANDVAK YFAILPALFV TAYPQLGVLN
610 620 630 640 650
VMGLHSPTSA VLSAVIFNAL IIPVLIPLAL RGVPYQPMSA GALLNRNLLV
660 670
YGGGGILVPF IAIKLIDLLI GGLMS
Length:675
Mass (Da):70,302
Last modified:May 1, 2000 - v1
Checksum:i0A033AAB471FC5BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001826 Genomic DNA Translation: AAF12535.1
PIRiA75627
RefSeqiNP_051616.1, NC_000958.1
WP_010883953.1, NZ_CP015083.1

Genome annotation databases

EnsemblBacteriaiAAF12535; AAF12535; DR_B0083
GeneIDi1799773
KEGGidra:DR_B0083
PATRICifig|243230.17.peg.83

Similar proteinsi

Entry informationi

Entry nameiKDPB_DEIRA
AccessioniPrimary (citable) accession number: Q9RZP0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: May 1, 2000
Last modified: February 28, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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