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UniProtKB - Q9RXJ5 (RL16_DEIRA)
Protein
50S ribosomal protein L16
Gene
rplP
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Functioni
Binds the 5S and 23S rRNAs and is also seen to make contacts with the A and P site tRNAs. Interacts with A site tRNA mimics, and is probably one of the key factors, along with a helix of the 23S rRNA, in positioning tRNA stems in the peptidyl-transferase center.
GO - Molecular functioni
- rRNA binding Source: GO_Central
- structural constituent of ribosome Source: GO_Central
- tRNA binding Source: UniProtKB-KW
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L16 |
Gene namesi | Name:rplP Ordered Locus Names:DR_0318 |
Organismi | Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) |
Taxonomic identifieri | 243230 [NCBI] |
Taxonomic lineagei | Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed | |||
ChainiPRO_0000062093 | 2 – 141 | 50S ribosomal protein L16Add BLAST | 140 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit. Contacts the CTC protein (RL25).
6 PublicationsProtein-protein interaction databases
IntActi | Q9RXJ5, 1 interactor |
STRINGi | 243230.DR_0318 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | Q9RXJ5 |
SMRi | Q9RXJ5 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q9RXJ5 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL16 family.Curated
Phylogenomic databases
eggNOGi | COG0197, Bacteria |
HOGENOMi | CLU_078858_2_1_0 |
InParanoidi | Q9RXJ5 |
OMAi | KGAVEYW |
OrthoDBi | 1786618at2 |
Family and domain databases
CDDi | cd01433, Ribosomal_L16_L10e, 1 hit |
Gene3Di | 3.90.1170.10, 1 hit |
HAMAPi | MF_01342, Ribosomal_L16, 1 hit |
InterProi | View protein in InterPro IPR016180, Ribosomal_L10e/L16 IPR036920, Ribosomal_L10e/L16_sf IPR000114, Ribosomal_L16 IPR020798, Ribosomal_L16_CS |
PANTHERi | PTHR12220, PTHR12220, 1 hit |
Pfami | View protein in Pfam PF00252, Ribosomal_L16, 1 hit |
PRINTSi | PR00060, RIBOSOMALL16 |
SUPFAMi | SSF54686, SSF54686, 1 hit |
TIGRFAMsi | TIGR01164, rplP_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00586, RIBOSOMAL_L16_1, 1 hit PS00701, RIBOSOMAL_L16_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9RXJ5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLPKRTKFR KQFRGRMTGD AKGGDYVAFG DYGLIAMEPA WIKSNQIEAC
60 70 80 90 100
RIVMSRHFRR GGKIYIRIFP DKPVTKKPAE TRMGKGKGAV EYWVSVVKPG
110 120 130 140
RVMFEVAGVT EEQAKEAFRL AGHKLPIQTK MVKREVYDEA Q
Sequence cautioni
The sequence AAF09899 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000513 Genomic DNA Translation: AAF09899.1 Different initiation. |
PIRi | F75534 |
RefSeqi | NP_294041.1, NC_001263.1 WP_025567820.1, NZ_CP015081.1 |
Genome annotation databases
EnsemblBacteriai | AAF09899; AAF09899; DR_0318 |
GeneIDi | 59165585 |
KEGGi | dra:DR_0318 |
PATRICi | fig|243230.17.peg.484 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000513 Genomic DNA Translation: AAF09899.1 Different initiation. |
PIRi | F75534 |
RefSeqi | NP_294041.1, NC_001263.1 WP_025567820.1, NZ_CP015081.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1NJM | X-ray | 3.60 | K | 1-141 | [»] | |
1NJP | X-ray | 3.50 | K | 1-141 | [»] | |
1NKW | X-ray | 3.10 | K | 1-141 | [»] | |
1NWX | X-ray | 3.50 | K | 1-141 | [»] | |
1NWY | X-ray | 3.30 | K | 1-141 | [»] | |
1SM1 | X-ray | 3.42 | K | 1-141 | [»] | |
1XBP | X-ray | 3.50 | K | 1-141 | [»] | |
1Y69 | X-ray | 3.33 | K | 1-141 | [»] | |
2ZJP | X-ray | 3.70 | J | 1-141 | [»] | |
2ZJQ | X-ray | 3.30 | J | 1-141 | [»] | |
2ZJR | X-ray | 2.91 | J | 1-141 | [»] | |
3CF5 | X-ray | 3.30 | J | 1-141 | [»] | |
3DLL | X-ray | 3.50 | J | 1-141 | [»] | |
3PIO | X-ray | 3.25 | J | 1-141 | [»] | |
3PIP | X-ray | 3.45 | J | 1-141 | [»] | |
4IO9 | X-ray | 3.20 | J | 1-141 | [»] | |
4IOA | X-ray | 3.20 | J | 1-141 | [»] | |
4IOC | X-ray | 3.60 | J | 1-141 | [»] | |
4U67 | X-ray | 3.65 | J | 1-141 | [»] | |
4V49 | X-ray | 8.70 | K | 7-130 | [»] | |
4V4A | X-ray | 9.50 | K | 7-130 | [»] | |
4V4G | X-ray | 11.50 | N | 7-130 | [»] | |
4WFN | X-ray | 3.54 | J | 1-141 | [»] | |
5DM6 | X-ray | 2.90 | J | 5-140 | [»] | |
5DM7 | X-ray | 3.00 | J | 5-140 | [»] | |
5JVG | X-ray | 3.43 | J | 1-141 | [»] | |
5JVH | X-ray | 3.58 | J | 1-141 | [»] | |
7A0R | X-ray | 3.30 | J | 5-140 | [»] | |
7A0S | X-ray | 3.22 | J | 5-140 | [»] | |
7A18 | X-ray | 3.40 | J | 5-138 | [»] | |
AlphaFoldDBi | Q9RXJ5 | |||||
SMRi | Q9RXJ5 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | Q9RXJ5, 1 interactor |
STRINGi | 243230.DR_0318 |
Genome annotation databases
EnsemblBacteriai | AAF09899; AAF09899; DR_0318 |
GeneIDi | 59165585 |
KEGGi | dra:DR_0318 |
PATRICi | fig|243230.17.peg.484 |
Phylogenomic databases
eggNOGi | COG0197, Bacteria |
HOGENOMi | CLU_078858_2_1_0 |
InParanoidi | Q9RXJ5 |
OMAi | KGAVEYW |
OrthoDBi | 1786618at2 |
Miscellaneous databases
EvolutionaryTracei | Q9RXJ5 |
Family and domain databases
CDDi | cd01433, Ribosomal_L16_L10e, 1 hit |
Gene3Di | 3.90.1170.10, 1 hit |
HAMAPi | MF_01342, Ribosomal_L16, 1 hit |
InterProi | View protein in InterPro IPR016180, Ribosomal_L10e/L16 IPR036920, Ribosomal_L10e/L16_sf IPR000114, Ribosomal_L16 IPR020798, Ribosomal_L16_CS |
PANTHERi | PTHR12220, PTHR12220, 1 hit |
Pfami | View protein in Pfam PF00252, Ribosomal_L16, 1 hit |
PRINTSi | PR00060, RIBOSOMALL16 |
SUPFAMi | SSF54686, SSF54686, 1 hit |
TIGRFAMsi | TIGR01164, rplP_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00586, RIBOSOMAL_L16_1, 1 hit PS00701, RIBOSOMAL_L16_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RL16_DEIRA | |
Accessioni | Q9RXJ5Primary (citable) accession number: Q9RXJ5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 15, 2004 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 131 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families