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UniProtKB - Q9RXJ1 (RL24_DEIRA)
Protein
50S ribosomal protein L24
Gene
rplX
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Functioni
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
By similarityOne of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. Contacts trigger factor (TF) when it is bound to the ribosome; this contact may expose a hydrophobic crevice in TF (PubMed:16271892).
1 PublicationGO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: GO_Central
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L24 |
Gene namesi | Name:rplX Ordered Locus Names:DR_0322 |
Organismi | Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) |
Taxonomic identifieri | 243230 [NCBI] |
Taxonomic lineagei | Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000130653 | 1 – 115 | 50S ribosomal protein L24Add BLAST | 115 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit. Contacts trigger factor when it is bound to the ribosome (PubMed:16271892).
7 PublicationsProtein-protein interaction databases
IntActi | Q9RXJ1, 1 interactor |
STRINGi | 243230.DR_0322 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | Q9RXJ1 |
SMRi | Q9RXJ1 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q9RXJ1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL24 family.Curated
Phylogenomic databases
eggNOGi | COG0198, Bacteria |
HOGENOMi | CLU_093315_2_3_0 |
InParanoidi | Q9RXJ1 |
OMAi | HVKPTQE |
OrthoDBi | 2040741at2 |
Family and domain databases
CDDi | cd06089, KOW_RPL26, 1 hit |
Gene3Di | 2.30.30.30, 1 hit |
HAMAPi | MF_01326_B, Ribosomal_L24_B, 1 hit |
InterProi | View protein in InterPro IPR005824, KOW IPR041988, KOW_RPL26/RPL24 IPR014722, Rib_L2_dom2 IPR003256, Ribosomal_L24 IPR005825, Ribosomal_L24/26_CS IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR12903, PTHR12903, 1 hit |
Pfami | View protein in Pfam PF00467, KOW, 1 hit PF17136, ribosomal_L24, 1 hit |
SMARTi | View protein in SMART SM00739, KOW, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit |
TIGRFAMsi | TIGR01079, rplX_bact, 1 hit |
PROSITEi | View protein in PROSITE PS01108, RIBOSOMAL_L24, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9RXJ1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRPSAGSHH NDKLHFKKGD TVIVLSGKHK GQTGKVLLAL PRDQKVVVEG
60 70 80 90 100
VNVITKNVKP SMTNPQGGQE QRELALHASK VALVDPETGK ATRVRKQIVD
110
GKKVRVAVAS GKTID
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000513 Genomic DNA Translation: AAF09903.1 |
PIRi | B75535 |
RefSeqi | NP_294045.1, NC_001263.1 WP_010886967.1, NZ_CP015081.1 |
Genome annotation databases
EnsemblBacteriai | AAF09903; AAF09903; DR_0322 |
KEGGi | dra:DR_0322 |
PATRICi | fig|243230.17.peg.488 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000513 Genomic DNA Translation: AAF09903.1 |
PIRi | B75535 |
RefSeqi | NP_294045.1, NC_001263.1 WP_010886967.1, NZ_CP015081.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1NKW | X-ray | 3.10 | S | 1-115 | [»] | |
1NWX | X-ray | 3.50 | S | 1-115 | [»] | |
1NWY | X-ray | 3.30 | S | 1-115 | [»] | |
1SM1 | X-ray | 3.42 | S | 1-115 | [»] | |
1XBP | X-ray | 3.50 | S | 1-115 | [»] | |
2D3O | X-ray | 3.35 | S | 1-115 | [»] | |
2ZJP | X-ray | 3.70 | R | 1-115 | [»] | |
2ZJQ | X-ray | 3.30 | R | 1-115 | [»] | |
2ZJR | X-ray | 2.91 | R | 1-115 | [»] | |
3CF5 | X-ray | 3.30 | R | 1-115 | [»] | |
3DLL | X-ray | 3.50 | R | 1-115 | [»] | |
3PIO | X-ray | 3.25 | R | 1-115 | [»] | |
3PIP | X-ray | 3.45 | R | 1-115 | [»] | |
4IO9 | X-ray | 3.20 | R | 1-115 | [»] | |
4IOA | X-ray | 3.20 | R | 1-115 | [»] | |
4IOC | X-ray | 3.60 | R | 1-115 | [»] | |
4U67 | X-ray | 3.65 | R | 2-115 | [»] | |
4V49 | X-ray | 8.70 | S | 2-114 | [»] | |
4V4A | X-ray | 9.50 | S | 2-114 | [»] | |
4V4G | X-ray | 11.50 | V | 2-114 | [»] | |
4WFN | X-ray | 3.54 | R | 1-115 | [»] | |
5DM6 | X-ray | 2.90 | R | 4-113 | [»] | |
5DM7 | X-ray | 3.00 | R | 4-113 | [»] | |
5JVG | X-ray | 3.43 | R | 1-115 | [»] | |
5JVH | X-ray | 3.58 | R | 1-115 | [»] | |
7A0R | X-ray | 3.30 | R | 4-113 | [»] | |
7A0S | X-ray | 3.22 | R | 4-113 | [»] | |
7A18 | X-ray | 3.40 | R | 4-113 | [»] | |
AlphaFoldDBi | Q9RXJ1 | |||||
SMRi | Q9RXJ1 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | Q9RXJ1, 1 interactor |
STRINGi | 243230.DR_0322 |
Genome annotation databases
EnsemblBacteriai | AAF09903; AAF09903; DR_0322 |
KEGGi | dra:DR_0322 |
PATRICi | fig|243230.17.peg.488 |
Phylogenomic databases
eggNOGi | COG0198, Bacteria |
HOGENOMi | CLU_093315_2_3_0 |
InParanoidi | Q9RXJ1 |
OMAi | HVKPTQE |
OrthoDBi | 2040741at2 |
Miscellaneous databases
EvolutionaryTracei | Q9RXJ1 |
Family and domain databases
CDDi | cd06089, KOW_RPL26, 1 hit |
Gene3Di | 2.30.30.30, 1 hit |
HAMAPi | MF_01326_B, Ribosomal_L24_B, 1 hit |
InterProi | View protein in InterPro IPR005824, KOW IPR041988, KOW_RPL26/RPL24 IPR014722, Rib_L2_dom2 IPR003256, Ribosomal_L24 IPR005825, Ribosomal_L24/26_CS IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR12903, PTHR12903, 1 hit |
Pfami | View protein in Pfam PF00467, KOW, 1 hit PF17136, ribosomal_L24, 1 hit |
SMARTi | View protein in SMART SM00739, KOW, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit |
TIGRFAMsi | TIGR01079, rplX_bact, 1 hit |
PROSITEi | View protein in PROSITE PS01108, RIBOSOMAL_L24, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RL24_DEIRA | |
Accessioni | Q9RXJ1Primary (citable) accession number: Q9RXJ1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 15, 2004 |
Last sequence update: | May 1, 2000 | |
Last modified: | May 25, 2022 | |
This is version 126 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families