UniProtKB - Q9RWM1 (MOBA_DEIRA)
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Protein
Probable molybdenum cofactor guanylyltransferase
Gene
mobA
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Functioni
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.UniRule annotation
Catalytic activityi
GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.UniRule annotation
Cofactori
Mg2+UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 21 | GTPUniRule annotation | 1 | |
Binding sitei | 64 | GTPUniRule annotation | 1 | |
Metal bindingi | 93 | MagnesiumUniRule annotation | 1 | |
Binding sitei | 93 | GTPUniRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 9 – 11 | GTPUniRule annotation | 3 |
GO - Molecular functioni
- GTP binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
- molybdenum cofactor guanylyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- Mo-molybdopterin cofactor biosynthetic process Source: UniProtKB-KW
Keywordsi
Molecular function | Transferase |
Biological process | Molybdenum cofactor biosynthesis |
Ligand | GTP-binding, Magnesium, Metal-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Probable molybdenum cofactor guanylyltransferaseUniRule annotation (EC:2.7.7.77UniRule annotation)Short name: MoCo guanylyltransferaseUniRule annotation Alternative name(s): GTP:molybdopterin guanylyltransferaseUniRule annotation Mo-MPT guanylyltransferaseUniRule annotation Molybdopterin guanylyltransferaseUniRule annotation Molybdopterin-guanine dinucleotide synthaseUniRule annotation Short name: MGD synthaseUniRule annotation |
Gene namesi | Name:mobAUniRule annotation Ordered Locus Names:DR_0645 |
Organismi | Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) |
Taxonomic identifieri | 243230 [NCBI] |
Taxonomic lineagei | Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000134886 | 1 – 193 | Probable molybdenum cofactor guanylyltransferaseAdd BLAST | 193 |
Family & Domainsi
Domaini
The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.UniRule annotation
Sequence similaritiesi
Belongs to the MobA family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG41080QG. Bacteria. COG0746. LUCA. |
HOGENOMi | HOG000280425. |
InParanoidi | Q9RWM1. |
KOi | K03752. |
OMAi | LFNCNTP. |
OrthoDBi | POG091H05CW. |
Family and domain databases
CDDi | cd02503. MobA. 1 hit. |
Gene3Di | 3.90.550.10. 1 hit. |
HAMAPi | MF_00316. MobA. 1 hit. |
InterProi | View protein in InterPro IPR025877. MobA-like_NTP_Trfase. IPR013482. Molybde_CF_guanTrfase. IPR029044. Nucleotide-diphossugar_trans. |
Pfami | View protein in Pfam PF12804. NTP_transf_3. 1 hit. |
SUPFAMi | SSF53448. SSF53448. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q9RWM1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPLTAAITA GGASSRFGSD KALALWQGRP LLDQVAAGLA ACERRLLIAP
60 70 80 90 100
PGKYALPGWE TWPDTRPGEG PLAGLEVALT HAAPGWVAFT GVDNPALTSD
110 120 130 140 150
YWLTLLAACR PGMSSVQALH PERGPQPLGA LYHTALLPRV TGLLAAGERR
160 170 180 190
LRLTAPAEQT VLVTGLGAHF FQNVNRPADL AELSGRGEES LEV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000513 Genomic DNA. Translation: AAF10223.1. |
PIRi | B75493. |
RefSeqi | NP_294368.1. NC_001263.1. WP_010887290.1. NZ_CP015081.1. |
Genome annotation databases
EnsemblBacteriai | AAF10223; AAF10223; DR_0645. |
GeneIDi | 1798304. |
KEGGi | dra:DR_0645. |
PATRICi | fig|243230.17.peg.824. |
Similar proteinsi
Entry informationi
Entry namei | MOBA_DEIRA | |
Accessioni | Q9RWM1Primary (citable) accession number: Q9RWM1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 21, 2001 |
Last sequence update: | May 1, 2000 | |
Last modified: | October 25, 2017 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |