UniProtKB - Q9RTE3 (Q9RTE3_DEIRA)
Protein
Multifunctional fusion protein
Gene
secD
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Functioni
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
GO - Molecular functioni
GO - Biological processi
- intracellular protein transmembrane transport Source: UniProtKB-UniRule
- protein targeting Source: UniProtKB-UniRule
- protein transport Source: GO_Central
- protein transport by the Sec complex Source: UniProtKB-UniRule
Keywordsi
Biological process | Protein transport, TranslocationUniRule annotationARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Multifunctional fusion proteinUniRule annotationIncluding the following 2 domains: Protein translocase subunit SecDUniRule annotation Protein-export membrane protein SecFUniRule annotation |
Gene namesi | Name:secDUniRule annotation Synonyms:secFUniRule annotation Ordered Locus Names:DR_1822Imported |
Organismi | Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Imported |
Taxonomic identifieri | 243230 [NCBI] |
Taxonomic lineagei | Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus › |
Proteomesi |
|
Subcellular locationi
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 33 – 50 | HelicalUniRule annotationAdd BLAST | 18 | |
Transmembranei | 295 – 315 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 321 – 341 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 424 – 447 | HelicalUniRule annotationAdd BLAST | 24 | |
Transmembranei | 474 – 493 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 599 – 616 | HelicalUniRule annotationAdd BLAST | 18 | |
Transmembranei | 623 – 644 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 650 – 671 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 702 – 722 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 728 – 752 | HelicalUniRule annotationAdd BLAST | 25 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell membraneUniRule annotationARBA annotation, MembraneInteractioni
Subunit structurei
Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
UniRule annotationForms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
UniRule annotationProtein-protein interaction databases
STRINGi | 243230.DR_1822 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 620 – 751 | SSDInterPro annotationAdd BLAST | 132 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 28 | DisorderedSequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 18 | PolarSequence analysisAdd BLAST | 18 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | COG0341, Bacteria COG0342, Bacteria |
HOGENOMi | CLU_007894_3_2_0 |
InParanoidi | Q9RTE3 |
OMAi | RTVNTGM |
OrthoDBi | 410730at2 |
Family and domain databases
HAMAPi | MF_01463_B, SecD_B, 1 hit MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR005791, SecD IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS IPR005665, SecF_bac IPR000731, SSD |
PANTHERi | PTHR30081, PTHR30081, 2 hits |
Pfami | View protein in Pfam PF07549, Sec_GG, 2 hits PF02355, SecD_SecF, 2 hits |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00916, 2A0604s01, 2 hits TIGR00966, 3a0501s07, 1 hit TIGR01129, secD, 1 hit |
PROSITEi | View protein in PROSITE PS50156, SSD, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9RTE3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTYGSKQVRK TSGSNRRPPP PRRSGGVSRP NPWTALLLLL TLLGSLLYIW
60 70 80 90 100
RPWEHKNDPW SLWNDQYQFM TLGLDLKGGL RIELAPESGT ATRDELDRVK
110 120 130 140 150
TVIENRINAL GVAEPTVTVS GGKRVVVEIP GATPAVQDRA RSIIQQTARL
160 170 180 190 200
EFRIVNSDAK PDPAVREKNP RSSGYTLAQL GPVVATGETI ADATSGTDQR
210 220 230 240 250
SGQWVVNFKT TDAGAKTFGD FTGKNVNRLM AVVLDDQIQS VATINQRLFR
260 270 280 290 300
DIQISGNFTP EEASQLALVL KSGALPIKIV TAAERSIGPS LGADAIRSGA
310 320 330 340 350
IAALVGIGLV FVMLFAYYGL WFGLVGALGL LFSSIIILGI LGGFGATLTL
360 370 380 390 400
PGIAGLVLTI GAAVDGNVIS FERIKEELAR GKGIKNAIGA GYEHSTAAIL
410 420 430 440 450
DVNASHLLSA LALYNYSTGA VKGFAVTLII GVIASTFSNL VFAKWFMQWL
460 470 480 490 500
AQRRPNMSAP QWIKHTHFDF MKPAKVITTL SVLLALAGAA LVATRGLNYG
510 520 530 540 550
VDFAPGTTLT ARVDRQVTTE QLRNSVIGAG VSKVTGQSAT IQRDTTPGQQ
560 570 580 590 600
GQNFTVKVPE LNDAEVKQIG AAIGKLPQGQ VLASETVGPA VGKELTQKTI
610 620 630 640 650
YAVLLGLGLI LVYVGFRFDF IMGLGSIIAA IHDVAIAMGL FSLLGLEFTV
660 670 680 690 700
ASVAALLTLI GYSLNDSIIV SDRIRENMKT MRGHSYREIV NAAINQTLSR
710 720 730 740 750
TVMTSVSTML PLISLLIFGG PVLRDFSLIL LVGILVGTYS SIYIVAPLVV
760
YFEEWRDKNR AAKPVTNS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000513 Genomic DNA Translation: AAF11371.1 |
PIRi | F75350 |
RefSeqi | NP_295545.1, NC_001263.1 WP_010888457.1, NZ_CP015081.1 |
Genome annotation databases
EnsemblBacteriai | AAF11371; AAF11371; DR_1822 |
KEGGi | dra:DR_1822 |
PATRICi | fig|243230.17.peg.2034 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000513 Genomic DNA Translation: AAF11371.1 |
PIRi | F75350 |
RefSeqi | NP_295545.1, NC_001263.1 WP_010888457.1, NZ_CP015081.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5XAM | X-ray | 4.00 | A/B | 28-768 | [»] | |
5XAN | X-ray | 2.75 | A/B | 28-768 | [»] | |
5XAP | X-ray | 2.60 | A | 28-768 | [»] | |
SMRi | Q9RTE3 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 243230.DR_1822 |
Genome annotation databases
EnsemblBacteriai | AAF11371; AAF11371; DR_1822 |
KEGGi | dra:DR_1822 |
PATRICi | fig|243230.17.peg.2034 |
Phylogenomic databases
eggNOGi | COG0341, Bacteria COG0342, Bacteria |
HOGENOMi | CLU_007894_3_2_0 |
InParanoidi | Q9RTE3 |
OMAi | RTVNTGM |
OrthoDBi | 410730at2 |
Family and domain databases
HAMAPi | MF_01463_B, SecD_B, 1 hit MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR005791, SecD IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS IPR005665, SecF_bac IPR000731, SSD |
PANTHERi | PTHR30081, PTHR30081, 2 hits |
Pfami | View protein in Pfam PF07549, Sec_GG, 2 hits PF02355, SecD_SecF, 2 hits |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00916, 2A0604s01, 2 hits TIGR00966, 3a0501s07, 1 hit TIGR01129, secD, 1 hit |
PROSITEi | View protein in PROSITE PS50156, SSD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9RTE3_DEIRA | |
Accessioni | Q9RTE3Primary (citable) accession number: Q9RTE3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |