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Entry version 130 (02 Dec 2020)
Sequence version 1 (01 May 2000)
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Protein

Multifunctional fusion protein

Gene

secD

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, TranslocationUniRule annotationARBA annotation, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Multifunctional fusion proteinUniRule annotation
Including the following 2 domains:
Protein translocase subunit SecDUniRule annotation
Protein-export membrane protein SecFUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:secDUniRule annotation
Synonyms:secFUniRule annotation
Ordered Locus Names:DR_1822Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri243230 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002524 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei33 – 50HelicalUniRule annotationAdd BLAST18
Transmembranei295 – 315HelicalUniRule annotationAdd BLAST21
Transmembranei321 – 341HelicalUniRule annotationAdd BLAST21
Transmembranei424 – 447HelicalUniRule annotationAdd BLAST24
Transmembranei474 – 493HelicalUniRule annotationAdd BLAST20
Transmembranei599 – 616HelicalUniRule annotationAdd BLAST18
Transmembranei623 – 644HelicalUniRule annotationAdd BLAST22
Transmembranei650 – 671HelicalUniRule annotationAdd BLAST22
Transmembranei702 – 722HelicalUniRule annotationAdd BLAST21
Transmembranei728 – 752HelicalUniRule annotationAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationARBA annotation, Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.

UniRule annotation

Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.

UniRule annotation

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
243230.DR_1822

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9RTE3

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini620 – 751SSDInterPro annotationAdd BLAST132

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 28DisorderedSequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 18PolarSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SecD/SecF family. SecD subfamily.UniRule annotation
Belongs to the SecD/SecF family. SecF subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0341, Bacteria
COG0342, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007894_3_2_0

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9RTE3

Identification of Orthologs from Complete Genome Data

More...
OMAi
RTVNTGM

Database of Orthologous Groups

More...
OrthoDBi
410730at2

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_01463_B, SecD_B, 1 hit
MF_01464_B, SecF_B, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005791, SecD
IPR022813, SecD/SecF_arch_bac
IPR022645, SecD/SecF_bac
IPR022646, SecD/SecF_CS
IPR005665, SecF_bac
IPR000731, SSD

The PANTHER Classification System

More...
PANTHERi
PTHR30081, PTHR30081, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07549, Sec_GG, 2 hits
PF02355, SecD_SecF, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01755, SECFTRNLCASE

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00916, 2A0604s01, 2 hits
TIGR00966, 3a0501s07, 1 hit
TIGR01129, secD, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50156, SSD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9RTE3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTYGSKQVRK TSGSNRRPPP PRRSGGVSRP NPWTALLLLL TLLGSLLYIW
60 70 80 90 100
RPWEHKNDPW SLWNDQYQFM TLGLDLKGGL RIELAPESGT ATRDELDRVK
110 120 130 140 150
TVIENRINAL GVAEPTVTVS GGKRVVVEIP GATPAVQDRA RSIIQQTARL
160 170 180 190 200
EFRIVNSDAK PDPAVREKNP RSSGYTLAQL GPVVATGETI ADATSGTDQR
210 220 230 240 250
SGQWVVNFKT TDAGAKTFGD FTGKNVNRLM AVVLDDQIQS VATINQRLFR
260 270 280 290 300
DIQISGNFTP EEASQLALVL KSGALPIKIV TAAERSIGPS LGADAIRSGA
310 320 330 340 350
IAALVGIGLV FVMLFAYYGL WFGLVGALGL LFSSIIILGI LGGFGATLTL
360 370 380 390 400
PGIAGLVLTI GAAVDGNVIS FERIKEELAR GKGIKNAIGA GYEHSTAAIL
410 420 430 440 450
DVNASHLLSA LALYNYSTGA VKGFAVTLII GVIASTFSNL VFAKWFMQWL
460 470 480 490 500
AQRRPNMSAP QWIKHTHFDF MKPAKVITTL SVLLALAGAA LVATRGLNYG
510 520 530 540 550
VDFAPGTTLT ARVDRQVTTE QLRNSVIGAG VSKVTGQSAT IQRDTTPGQQ
560 570 580 590 600
GQNFTVKVPE LNDAEVKQIG AAIGKLPQGQ VLASETVGPA VGKELTQKTI
610 620 630 640 650
YAVLLGLGLI LVYVGFRFDF IMGLGSIIAA IHDVAIAMGL FSLLGLEFTV
660 670 680 690 700
ASVAALLTLI GYSLNDSIIV SDRIRENMKT MRGHSYREIV NAAINQTLSR
710 720 730 740 750
TVMTSVSTML PLISLLIFGG PVLRDFSLIL LVGILVGTYS SIYIVAPLVV
760
YFEEWRDKNR AAKPVTNS
Length:768
Mass (Da):82,284
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCDFF423F4070B6FD
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE000513 Genomic DNA Translation: AAF11371.1

Protein sequence database of the Protein Information Resource

More...
PIRi
F75350

NCBI Reference Sequences

More...
RefSeqi
NP_295545.1, NC_001263.1
WP_010888457.1, NZ_CP015081.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAF11371; AAF11371; DR_1822

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dra:DR_1822

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|243230.17.peg.2034

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA Translation: AAF11371.1
PIRiF75350
RefSeqiNP_295545.1, NC_001263.1
WP_010888457.1, NZ_CP015081.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5XAMX-ray4.00A/B28-768[»]
5XANX-ray2.75A/B28-768[»]
5XAPX-ray2.60A28-768[»]
SMRiQ9RTE3
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi243230.DR_1822

Genome annotation databases

EnsemblBacteriaiAAF11371; AAF11371; DR_1822
KEGGidra:DR_1822
PATRICifig|243230.17.peg.2034

Phylogenomic databases

eggNOGiCOG0341, Bacteria
COG0342, Bacteria
HOGENOMiCLU_007894_3_2_0
InParanoidiQ9RTE3
OMAiRTVNTGM
OrthoDBi410730at2

Family and domain databases

HAMAPiMF_01463_B, SecD_B, 1 hit
MF_01464_B, SecF_B, 1 hit
InterProiView protein in InterPro
IPR005791, SecD
IPR022813, SecD/SecF_arch_bac
IPR022645, SecD/SecF_bac
IPR022646, SecD/SecF_CS
IPR005665, SecF_bac
IPR000731, SSD
PANTHERiPTHR30081, PTHR30081, 2 hits
PfamiView protein in Pfam
PF07549, Sec_GG, 2 hits
PF02355, SecD_SecF, 2 hits
PRINTSiPR01755, SECFTRNLCASE
TIGRFAMsiTIGR00916, 2A0604s01, 2 hits
TIGR00966, 3a0501s07, 1 hit
TIGR01129, secD, 1 hit
PROSITEiView protein in PROSITE
PS50156, SSD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9RTE3_DEIRA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9RTE3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: December 2, 2020
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Reference proteomeImported
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