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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei67NucleophileUniRule annotation1
Binding sitei127SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:DR_2290
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000573711 – 280tRNA pseudouridine synthase AAdd BLAST280

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi243230.DR_2290

Structurei

3D structure databases

ProteinModelPortaliQ9RS37
SMRiQ9RS37
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248674
InParanoidiQ9RS37
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 1 hit
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

Q9RS37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDADPPRLYA PPPGFTRLRL TVAWDGRDYA GWQEQRNAVS VQETLQTALH
60 70 80 90 100
ALGGEGALRP VSAGRTDAGV HAEAMPLHWD VPTTFRVPLV QLPRALNAWL
110 120 130 140 150
PASVSVLSAE VAPAGFHARF SCTERRYVYR LWVAPQRHPL WAGRALHVPG
160 170 180 190 200
PLDAEAMNRA AQSLIGLHDF AAFATREDRQ TVRDLLRLEV QPQGELWDIH
210 220 230 240 250
VAGESFLRHM VRGLVGTLLL VGQGKLGAAE VEGILASRER ARAGANVPPG
260 270 280
GLYFAGAEYG VRRVEGRSGN GGEPGTHRGR
Length:280
Mass (Da):30,455
Last modified:May 1, 2000 - v1
Checksum:iEB603B442127EDB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA Translation: AAF11837.1
PIRiD75291
RefSeqiNP_296011.1, NC_001263.1
WP_010888918.1, NZ_CP015081.1

Genome annotation databases

EnsemblBacteriaiAAF11837; AAF11837; DR_2290
GeneIDi1797369
KEGGidra:DR_2290
PATRICifig|243230.17.peg.2519

Similar proteinsi

Entry informationi

Entry nameiTRUA_DEIRA
AccessioniPrimary (citable) accession number: Q9RS37
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: May 1, 2000
Last modified: July 18, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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