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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei137UniRule annotation1
Active sitei569UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:SCO3127
ORF Names:SCE66.06c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001666281 – 911Phosphoenolpyruvate carboxylaseAdd BLAST911

Proteomic databases

PRIDEiQ9RNU9

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO3127

Structurei

3D structure databases

ProteinModelPortaliQ9RNU9
SMRiQ9RNU9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
InParanoidiQ9RNU9
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O
PhylomeDBiQ9RNU9

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9RNU9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSADDQTTT TTSSELRADI RRLGDLLGET LVRQEGPELL ELVEKVRRLT
60 70 80 90 100
REDGEAAAEL LRGTELETAA KLVRAFSTYF HLANVTEQVH RGRELGAKRA
110 120 130 140 150
AEGGLLARTA DRLKDADPEH LRETVRNLNV RPVFTAHPTE AARRSVLNKL
160 170 180 190 200
RRIAALLDTP VNESDRRRLD TRLAENIDLV WQTDELRVVR PEPADEARNA
210 220 230 240 250
IYYLDELHLG AVGDVLEDLT AELERAGVKL PDDTRPLTFG TWIGGDRDGN
260 270 280 290 300
PNVTPQVTWD VLILQHEHGI NDALEMIDEL RGFLSNSIRY AGATEELLAS
310 320 330 340 350
LQADLERLPE ISPRYKRLNA EEPYRLKATC IRQKLENTKQ RLAKGTPHED
360 370 380 390 400
GRDYLGTAQL IDDLRIVQTS LREHRGGLFA DGRLARTIRT LAAFGLQLAT
410 420 430 440 450
MDVREHADAH HHALGQLFDR LGEESWRYAD MPREYRTKLL AKELRSRRPL
460 470 480 490 500
APSPAPVDAP GEKTLGVFQT VRRALEVFGP EVIESYIISM CQGADDVFAA
510 520 530 540 550
AVLAREAGLI DLHAGWAKIG IVPLLETTDE LKAADTILED LLADPSYRRL
560 570 580 590 600
VALRGDVQEV MLGYSDSSKF GGITTSQWEI HRAQRRLRDV AHRYGVRLRL
610 620 630 640 650
FHGRGGTVGR GGGPTHDAIL AQPWGTLEGE IKVTEQGEVI SDKYLIPALA
660 670 680 690 700
RENLELTVAA TLQASALHTA PRQSDEALAR WDAAMDVVSD AAHTAYRHLV
710 720 730 740 750
EDPDLPTYFL ASTPVDQLAD LHLGSRPSRR PGSGVSLDGL RAIPWVFGWT
760 770 780 790 800
QSRQIVPGWY GVGSGLKALR EAGLDTVLDE MHQQWHFFRN FISNVEMTLA
810 820 830 840 850
KTDLRIAQHY VDTLVPDELK HVFDTIKAEH ELTVAEVLRV TGESELLDAD
860 870 880 890 900
PVLKQTFTIR DAYLDPISYL QVALLGRQRE AAAANEDPDP LLARALLLTV
910
NGVAAGLRNT G
Length:911
Mass (Da):101,297
Last modified:May 1, 2000 - v1
Checksum:i5192E0BB96881273
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF177946 Genomic DNA Translation: AAD53311.1
AF160253 Genomic DNA Translation: AAM54458.1
AL939115 Genomic DNA Translation: CAB95920.1
RefSeqiNP_627344.1, NC_003888.3
WP_003975687.1, NC_003888.3

Genome annotation databases

EnsemblBacteriaiCAB95920; CAB95920; CAB95920
GeneIDi1098561
KEGGisco:SCO3127
PATRICifig|100226.15.peg.3191

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF177946 Genomic DNA Translation: AAD53311.1
AF160253 Genomic DNA Translation: AAM54458.1
AL939115 Genomic DNA Translation: CAB95920.1
RefSeqiNP_627344.1, NC_003888.3
WP_003975687.1, NC_003888.3

3D structure databases

ProteinModelPortaliQ9RNU9
SMRiQ9RNU9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO3127

Proteomic databases

PRIDEiQ9RNU9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB95920; CAB95920; CAB95920
GeneIDi1098561
KEGGisco:SCO3127
PATRICifig|100226.15.peg.3191

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
InParanoidiQ9RNU9
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O
PhylomeDBiQ9RNU9

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCAPP_STRCO
AccessioniPrimary (citable) accession number: Q9RNU9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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