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Entry version 162 (07 Oct 2020)
Sequence version 1 (01 May 2000)
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Protein
Submitted name:

LuxR family transcriptional regulator

Gene

phzR

Organism
Pseudomonas aeruginosa
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivatorARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
LuxR family transcriptional regulatorImported
Submitted name:
PhzRImported
Submitted name:
Quorum-sensing control repressorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:phzRImported
Synonyms:qscRImported
ORF Names:ALP65_03645Imported, C0044_14205Imported, CAZ10_26210Imported, DT376_23495Imported, DY930_34595Imported, DZ962_05695Imported, E4V10_12590Imported, ECC04_019105Imported, F7O98_25585Imported, FC629_17500Imported, FDK04_17040Imported, IPC116_18515Imported, IPC1323_26100Imported, IPC1481_00290Imported, IPC1509_32940Imported, IPC36_04320Imported, IPC620_12285Imported, IPC669_03745Imported, NCTC10662_04415Imported, NCTC12951_04801Imported, NCTC13621_00173Imported, PAMH19_5306Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas aeruginosaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri287 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000297623 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000043988 Componenti: Unassembled WGS sequence
  • UP000253594 Componenti: Unassembled WGS sequence
  • UP000272646 Componenti: Unassembled WGS sequence
  • UP000278438 Componenti: Unassembled WGS sequence
  • UP000341211 Componenti: Unassembled WGS sequence
  • UP000297232 Componenti: Unassembled WGS sequence
  • UP000372148 Componenti: Unassembled WGS sequence
  • UP000426765 Componenti: Unassembled WGS sequence
  • UP000270834 Componenti: Unassembled WGS sequence
  • UP000194857 Componenti: Unassembled WGS sequence
  • UP000258262 Componenti: Unassembled WGS sequence
  • UP000297361 Componenti: Unassembled WGS sequence
  • UP000424265 Componenti: Chromosome
  • UP000297845 Componenti: Unassembled WGS sequence
  • UP000344659 Componenti: Unassembled WGS sequence
  • UP000297376 Componenti: Unassembled WGS sequence
  • UP000297560 Componenti: Unassembled WGS sequence
  • UP000297499 Componenti: Unassembled WGS sequence
  • UP000285404 Componenti: Unassembled WGS sequence
  • UP000422128 Componenti: Chromosome
  • UP000247072 Componenti: Unassembled WGS sequence

Organism-specific databases

Pseudomonas genome database

More...
PseudoCAPi
PA1898

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL1075213

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Database of interacting proteins

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DIPi
DIP-59711N

STRING: functional protein association networks

More...
STRINGi
287.DR97_5949

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9RMS5

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini169 – 234HTH luxR-typeInterPro annotationAdd BLAST66

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the autoinducer-regulated transcriptional regulatory protein family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG2197, Bacteria

Database of Orthologous Groups

More...
OrthoDBi
1687028at2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06170, LuxR_C_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit
3.30.450.80, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016032, Sig_transdc_resp-reg_C-effctor
IPR005143, TF_LuxR_autoind-bd_dom
IPR036693, TF_LuxR_autoind-bd_dom_sf
IPR000792, Tscrpt_reg_LuxR_C
IPR036388, WH-like_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03472, Autoind_bind, 1 hit
PF00196, GerE, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00038, HTHLUXR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00421, HTH_LUXR, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46894, SSF46894, 1 hit
SSF75516, SSF75516, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00622, HTH_LUXR_1, 1 hit
PS50043, HTH_LUXR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9RMS5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHDEREGYLE ILSRITTEEE FFSLVLEICG NYGFEFFSFG ARAPFPLTAP
60 70 80 90 100
KYHFLSNYPG EWKSRYISED YTSIDPIVRH GLLEYTPLIW NGEDFQENRF
110 120 130 140 150
FWEEALHHGI RHGWSIPVRG KYGLISMLSL VRSSESIAAT EILEKESFLL
160 170 180 190 200
WITSMLQATF GDLLAPRIVP ESNVRLTARE TEMLKWTAVG KTYGEIGLIL
210 220 230
SIDQRTVKFH IVNAMRKLNS SNKAEATMKA YAIGLLN
Length:237
Mass (Da):27,254
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD4A62CD5ADDD57EE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF190630 Genomic DNA Translation: AAF01471.1
CDAZ01000022 Genomic DNA Translation: CEI20178.1
VZIW01000074 Genomic DNA Translation: KAB0761171.1
NFFZ01000016 Genomic DNA Translation: OTI57720.1
QHLU01001103 Genomic DNA Translation: PXB97875.1
CP039988 Genomic DNA Translation: QGP97466.1
CP039990 Genomic DNA Translation: QGQ04201.1
QORE01000934 Genomic DNA Translation: RCI72489.1
QVBL01000004 Genomic DNA Translation: RFJ76781.1
RBSQ01001046 Genomic DNA Translation: RMS48604.1
NSVB01000002 Genomic DNA Translation: RPY77481.1
RXTB01000187 Genomic DNA Translation: RTR63861.1
RWMJ01000031 Genomic DNA Translation: TEE11344.1
RWNG01000001 Genomic DNA Translation: TEF49585.1
RWOM01000015 Genomic DNA Translation: TEH30190.1
RWPP01000004 Genomic DNA Translation: TEJ18856.1
RWTJ01000008 Genomic DNA Translation: TEO90507.1
RWUZ01000001 Genomic DNA Translation: TER59485.1
SRHR01000016 Genomic DNA Translation: TGA89142.1
RHMD02000002 Genomic DNA Translation: TGB21458.1
CAADJI010000001 Genomic DNA Translation: VFS93328.1
CAADJP010000001 Genomic DNA Translation: VFT07633.1
CAADJQ010000024 Genomic DNA Translation: VFT33223.1

Protein sequence database of the Protein Information Resource

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PIRi
D83407

NCBI Reference Sequences

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RefSeqi
WP_003118960.1, NZ_WYAF01000018.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CEI20178; CEI20178; PAMH19_5306
CRO11189; CRO11189; PAERUG_P32_London_17_VIM_2_10_11_01625
CRQ84527; CRQ84527; PAERUG_E15_London_28_01_14_06284

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
45710939

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pae:PA1898

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|287.1484.peg.393

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF190630 Genomic DNA Translation: AAF01471.1
CDAZ01000022 Genomic DNA Translation: CEI20178.1
VZIW01000074 Genomic DNA Translation: KAB0761171.1
NFFZ01000016 Genomic DNA Translation: OTI57720.1
QHLU01001103 Genomic DNA Translation: PXB97875.1
CP039988 Genomic DNA Translation: QGP97466.1
CP039990 Genomic DNA Translation: QGQ04201.1
QORE01000934 Genomic DNA Translation: RCI72489.1
QVBL01000004 Genomic DNA Translation: RFJ76781.1
RBSQ01001046 Genomic DNA Translation: RMS48604.1
NSVB01000002 Genomic DNA Translation: RPY77481.1
RXTB01000187 Genomic DNA Translation: RTR63861.1
RWMJ01000031 Genomic DNA Translation: TEE11344.1
RWNG01000001 Genomic DNA Translation: TEF49585.1
RWOM01000015 Genomic DNA Translation: TEH30190.1
RWPP01000004 Genomic DNA Translation: TEJ18856.1
RWTJ01000008 Genomic DNA Translation: TEO90507.1
RWUZ01000001 Genomic DNA Translation: TER59485.1
SRHR01000016 Genomic DNA Translation: TGA89142.1
RHMD02000002 Genomic DNA Translation: TGB21458.1
CAADJI010000001 Genomic DNA Translation: VFS93328.1
CAADJP010000001 Genomic DNA Translation: VFT07633.1
CAADJQ010000024 Genomic DNA Translation: VFT33223.1
PIRiD83407
RefSeqiWP_003118960.1, NZ_WYAF01000018.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3SZTX-ray2.55A/B1-237[»]
6CBQX-ray2.80A/B1-237[»]
6CC0X-ray2.50A/B1-237[»]
SMRiQ9RMS5
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

DIPiDIP-59711N
STRINGi287.DR97_5949

Chemistry databases

ChEMBLiCHEMBL1075213

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
880650

Genome annotation databases

EnsemblBacteriaiCEI20178; CEI20178; PAMH19_5306
CRO11189; CRO11189; PAERUG_P32_London_17_VIM_2_10_11_01625
CRQ84527; CRQ84527; PAERUG_E15_London_28_01_14_06284
GeneIDi45710939
KEGGipae:PA1898
PATRICifig|287.1484.peg.393

Organism-specific databases

PseudoCAPiPA1898

Phylogenomic databases

eggNOGiCOG2197, Bacteria
OrthoDBi1687028at2

Family and domain databases

CDDicd06170, LuxR_C_like, 1 hit
Gene3Di1.10.10.10, 1 hit
3.30.450.80, 1 hit
InterProiView protein in InterPro
IPR016032, Sig_transdc_resp-reg_C-effctor
IPR005143, TF_LuxR_autoind-bd_dom
IPR036693, TF_LuxR_autoind-bd_dom_sf
IPR000792, Tscrpt_reg_LuxR_C
IPR036388, WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF03472, Autoind_bind, 1 hit
PF00196, GerE, 1 hit
PRINTSiPR00038, HTHLUXR
SMARTiView protein in SMART
SM00421, HTH_LUXR, 1 hit
SUPFAMiSSF46894, SSF46894, 1 hit
SSF75516, SSF75516, 1 hit
PROSITEiView protein in PROSITE
PS00622, HTH_LUXR_1, 1 hit
PS50043, HTH_LUXR_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9RMS5_PSEAI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9RMS5
Secondary accession number(s): Q7DCE1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 7, 2020
This is version 162 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
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