UniProtKB - Q9RGG5 (PTRA_LACCA)
Protein
PTS system sorbose-specific EIIA component
Gene
sorA
Organism
Lactobacillus casei
Status
Functioni
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The enzyme II SorABCD PTS system is involved in L-sorbose transport.1 Publication
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 8 | Tele-phosphohistidine intermediatePROSITE-ProRule annotation1 Publication | 1 |
GO - Molecular functioni
- kinase activity Source: UniProtKB-KW
- phosphotransferase activity, alcohol group as acceptor Source: InterPro
GO - Biological processi
- phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW
Keywordsi
Molecular function | Kinase, Transferase |
Biological process | Phosphotransferase system, Sugar transport, Transport |
Protein family/group databases
TCDBi | 4.A.6.1.26, the pts mannose-fructose-sorbose (man) family |
Names & Taxonomyi
Protein namesi | Recommended name: PTS system sorbose-specific EIIA component1 PublicationAlternative name(s): EIIA-Sor1 Publication Sorbose-specific phosphotransferase enzyme IIA component1 Publication |
Gene namesi | Name:sorA1 Publication |
Organismi | Lactobacillus casei |
Taxonomic identifieri | 1582 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lacticaseibacillus |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Other locations
- cytoplasm Source: UniProtKB-SubCell
- integral component of membrane Source: InterPro
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000437530 | 1 – 138 | PTS system sorbose-specific EIIA componentAdd BLAST | 138 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 8 | Phosphohistidine; by HPr1 Publication | 1 |
Keywords - PTMi
PhosphoproteinPTM databases
iPTMneti | Q9RGG5 |
Expressioni
Inductioni
Induced by L-sorbose and repressed by D-glucose.1 Publication
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 125 | PTS EIIA type-4PROSITE-ProRule annotationAdd BLAST | 125 |
Domaini
The EIIA type-4 domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB type-4 domain.PROSITE-ProRule annotation
Phylogenomic databases
eggNOGi | COG2893, Bacteria |
Family and domain databases
CDDi | cd00006, PTS_IIA_man, 1 hit |
Gene3Di | 3.40.50.510, 1 hit |
InterProi | View protein in InterPro IPR013789, PTS_EIIA_man IPR004701, PTS_EIIA_man-typ IPR036662, PTS_EIIA_man-typ_sf IPR033887, PTS_IIA_man |
Pfami | View protein in Pfam PF03610, EIIA-man, 1 hit |
SUPFAMi | SSF53062, SSF53062, 1 hit |
TIGRFAMsi | TIGR00824, EIIA-man, 1 hit |
PROSITEi | View protein in PROSITE PS51096, PTS_EIIA_TYPE_4, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9RGG5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEIILVGHAH TAKAFKEAVE MIYGEVPNFH PIDFTPKEGL QSLTDKIVSA
60 70 80 90 100
IEPGKTASTL IITDLFSGTP YNASAELVLK KKAADVVAGM CLPMLLEVAV
110 120 130
NANNMSVSQL VSHLMKIKEE FSTSLSEKMT TNAKEDDF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF129168 Genomic DNA Translation: AAF24131.1 |
RefSeqi | WP_012490965.1, NZ_MODT01000074.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF129168 Genomic DNA Translation: AAF24131.1 |
RefSeqi | WP_012490965.1, NZ_MODT01000074.1 |
3D structure databases
SMRi | Q9RGG5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 543734.LCABL_04250 |
Protein family/group databases
TCDBi | 4.A.6.1.26, the pts mannose-fructose-sorbose (man) family |
PTM databases
iPTMneti | Q9RGG5 |
Phylogenomic databases
eggNOGi | COG2893, Bacteria |
Family and domain databases
CDDi | cd00006, PTS_IIA_man, 1 hit |
Gene3Di | 3.40.50.510, 1 hit |
InterProi | View protein in InterPro IPR013789, PTS_EIIA_man IPR004701, PTS_EIIA_man-typ IPR036662, PTS_EIIA_man-typ_sf IPR033887, PTS_IIA_man |
Pfami | View protein in Pfam PF03610, EIIA-man, 1 hit |
SUPFAMi | SSF53062, SSF53062, 1 hit |
TIGRFAMsi | TIGR00824, EIIA-man, 1 hit |
PROSITEi | View protein in PROSITE PS51096, PTS_EIIA_TYPE_4, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PTRA_LACCA | |
Accessioni | Q9RGG5Primary (citable) accession number: Q9RGG5 Secondary accession number(s): F2M4U9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 5, 2016 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 10, 2021 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |