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Protein

Alpha- and gamma-adaptin-binding protein p34

Gene

Aagab

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in endocytic recycling of growth factor receptors such as EGFR.By similarity

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha- and gamma-adaptin-binding protein p34
Gene namesi
Name:Aagab
Synonyms:P34
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi621601 Aagab

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000581371 – 315Alpha- and gamma-adaptin-binding protein p34Add BLAST315

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei310PhosphoserineCombined sources1
Modified residuei311PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9R0Z7
PeptideAtlasiQ9R0Z7
PRIDEiQ9R0Z7

PTM databases

iPTMnetiQ9R0Z7
PhosphoSitePlusiQ9R0Z7

Expressioni

Tissue specificityi

Widely expressed.1 Publication

Gene expression databases

BgeeiENSRNOG00000008424
GenevisibleiQ9R0Z7 RN

Interactioni

Subunit structurei

Associated with AP-1 and AP-2 complexes.1 Publication

Protein-protein interaction databases

BioGridi251245, 1 interactor
MINTiQ9R0Z7
STRINGi10116.ENSRNOP00000011385

Structurei

3D structure databases

SMRiQ9R0Z7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4273 Eukaryota
ENOG410XRVH LUCA
GeneTreeiENSGT00390000007218
HOGENOMiHOG000115322
InParanoidiQ9R0Z7
OMAiVMKNDRN
OrthoDBiEOG091G1A3H
PhylomeDBiQ9R0Z7

Family and domain databases

InterProiView protein in InterPro
IPR019341 Alpha/Gamma-adaptin-bd_p34
PANTHERiPTHR14659 PTHR14659, 1 hit

Sequencei

Sequence statusi: Complete.

Q9R0Z7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGVPCALV TSCSATFTGD RLVQHILGTE DAVVEATSSD AVRFYPWTID
60 70 80 90 100
NKYYSAEVNL CVVPSKCRVT AEIAEAVQAF VVYFDSTQKS GLDSVSSWLP
110 120 130 140 150
LAETWLPEVM ILVCDRVCED GINRQQAQEW CIKHGFELVE LCPEELPEED
160 170 180 190 200
DDFPESTGVK RIVQALNANV WSNVVMKNDR SQGFSLLNSL AGASRSVGSA
210 220 230 240 250
ESCQCEQEPS PTAERTESLP GHRSGACGPA GAQVDSIVDP MLDLDIQELA
260 270 280 290 300
SLTTGGGDLE NFERLFSKLK EMKDKAATLP HEQRKLHAEK VAKAFWMAIG
310
GDRDEIEGLS SDDEH
Length:315
Mass (Da):34,363
Last modified:May 1, 2000 - v1
Checksum:i7330E91679945A9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF178669 mRNA Translation: AAD51852.1
RefSeqiNP_599225.1, NM_134398.2
UniGeneiRn.163023

Genome annotation databases

EnsembliENSRNOT00000011385; ENSRNOP00000011385; ENSRNOG00000008424
GeneIDi171435
KEGGirno:171435
UCSCiRGD:621601 rat

Similar proteinsi

Entry informationi

Entry nameiAAGAB_RAT
AccessioniPrimary (citable) accession number: Q9R0Z7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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