Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - Q9QZX7 (SRR_MOUSE)

Entry version 159 (29 Sep 2021)
Sequence version 1 (01 May 2000)
Previous versions | rss
Add a publicationFeedback
Protein

Serine racemase

Gene

Srr

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.

5 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pyridoxal 5'-phosphate2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Allosterically activated by magnesium, and possibly also other divalent metal cations. Allosterically activated by ATP, ADP or GTP.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei51ATPCurated1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei56Proton acceptorBy similarity1
Active sitei84Proton acceptorBy similarity1
Binding sitei121ATPBy similarity1
Binding sitei135SubstrateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi210MagnesiumBy similarity1
Metal bindingi214Magnesium; via carbonyl oxygenBy similarity1
Metal bindingi216MagnesiumBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAllosteric enzyme, Isomerase, Lyase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Pyridoxal phosphate

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		4.3.1.17, 3474
5.1.1.18, 3474

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-977347, Serine biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Serine racemase1 Publication (EC:5.1.1.184 Publications)
Alternative name(s):
D-serine ammonia-lyase
D-serine dehydratase (EC:4.3.1.181 Publication)
L-serine ammonia-lyase
L-serine dehydratase (EC:4.3.1.173 Publications)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Srr
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1351636, Srr

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000001323

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi51K → A: Impairs ATP-binding inducing a 80% decrease in enzyme activity. 1
Mutagenesisi113C → S: Abolishes S-nitrosylation. 1 Publication1

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL1075306

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001856511 – 339Serine racemaseAdd BLAST339

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei56N6-(pyridoxal phosphate)lysineBy similarity1
Modified residuei71PhosphothreonineCombined sources1
Modified residuei113S-nitrosocysteine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

S-nitrosylated, leading to decrease the enzyme activity.1 Publication

Keywords - PTMi

Phosphoprotein, S-nitrosylation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9QZX7

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9QZX7

PeptideAtlas

More...PeptideAtlasi		Q9QZX7

PRoteomics IDEntifications database

More...PRIDEi		Q9QZX7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		257407 [Q9QZX7-1]
257408 [Q9QZX7-2]
257409 [Q9QZX7-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9QZX7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9QZX7

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9QZX7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in brain (at protein level). Brain.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000001323, Expressed in liver and 293 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9QZX7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9QZX7, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		205172, 9 interactors

Molecular INTeraction database

More...MINTi		Q9QZX7

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000113372

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		Q9QZX7

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9QZX7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9QZX7

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni238 – 239Substrate bindingBy similarity2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the serine/threonine dehydratase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1251, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00550000075026

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_021152_4_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9QZX7

Identification of Orthologs from Complete Genome Data

More...OMAi		LIHPFDH

Database of Orthologous Groups

More...OrthoDBi		943371at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9QZX7

TreeFam database of animal gene trees

More...TreeFami		TF313346

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.1100, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001926, PLP-dep
IPR000634, Ser/Thr_deHydtase_PyrdxlP-BS
IPR036052, Trypto_synt_PLP_dependent

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00291, PALP, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53686, SSF53686, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00165, DEHYDRATASE_SER_THR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9QZX7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MCAQYCISFA DVEKAHINIQ DSIHLTPVLT SSILNQIAGR NLFFKCELFQ 
        60         70         80         90        100
KTGSFKIRGA LNAIRGLIPD TPEEKPKAVV THSSGNHGQA LTYAAKLEGI 
       110        120        130        140        150
PAYIVVPQTA PNCKKLAIQA YGASIVYCDP SDESREKVTQ RIMQETEGIL 
       160        170        180        190        200
VHPNQEPAVI AGQGTIALEV LNQVPLVDAL VVPVGGGGMV AGIAITIKAL 
       210        220        230        240        250
KPSVKVYAAE PSNADDCYQS KLKGELTPNL HPPETIADGV KSSIGLNTWP 
       260        270        280        290        300
IIRDLVDDVF TVTEDEIKYA TQLVWGRMKL LIEPTAGVAL AAVLSQHFQT 
       310        320        330 
VSPEVKNVCI VLSGGNVDLT SLNWVGQAER PAPYQTVSV
Length:339
Mass (Da):36,359
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB9AE9A9336358728
GO
Isoform 2 (identifier: Q9QZX7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     174-198: Missing.

Show »
Length:314
Mass (Da):34,030
Checksum:i0BB6492649FF8491
GO
Isoform 3 (identifier: Q9QZX7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     183-339: Missing.

Show »
Length:182
Mass (Da):19,694
Checksum:i23075946C01AF288
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8Y5D6A8Y5D6_MOUSE
L-serine ammonia-lyase
Srr
113Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Z4YMF3Z4YMF3_MOUSE
L-serine ammonia-lyase
Srr
166Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAI24255 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti111P → T in BAC25712 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_025013174 – 198Missing in isoform 2. 1 PublicationAdd BLAST25
Alternative sequenceiVSP_025014183 – 339Missing in isoform 3. CuratedAdd BLAST157

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF148321 mRNA Translation: AAF08701.1
AK031687 mRNA Translation: BAC27514.1
AK028034 mRNA Translation: BAC25712.1
AK043738 mRNA Translation: BAC31637.1
AK157122 mRNA Translation: BAE33968.1
AK170096 mRNA Translation: BAE41561.1
AL604066 Genomic DNA Translation: CAI24252.1
AL604066 Genomic DNA Translation: CAI24253.1
AL604066 Genomic DNA Translation: CAI24254.1
AL604066 Genomic DNA Translation: CAI24255.1 Sequence problems.
BC011164 mRNA Translation: AAH11164.1
AB232340 mRNA Translation: BAE19920.1
AB232341 mRNA Translation: BAE19921.1
AB232342 mRNA Translation: BAE19922.1
AB232343 mRNA Translation: BAE19923.1
AB235396 mRNA Translation: BAE44529.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS25038.1 [Q9QZX7-1]
CCDS88190.1 [Q9QZX7-2]

NCBI Reference Sequences

More...RefSeqi		NP_001156783.1, NM_001163311.1 [Q9QZX7-1]
NP_038789.1, NM_013761.4 [Q9QZX7-1]
XP_006533520.1, XM_006533457.3 [Q9QZX7-1]
XP_017170058.1, XM_017314569.1 [Q9QZX7-1]
XP_017170059.1, XM_017314570.1
XP_017170060.1, XM_017314571.1 [Q9QZX7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000065211; ENSMUSP00000067552; ENSMUSG00000001323 [Q9QZX7-1]
ENSMUST00000108447; ENSMUSP00000104086; ENSMUSG00000001323 [Q9QZX7-2]
ENSMUST00000108448; ENSMUSP00000104087; ENSMUSG00000001323 [Q9QZX7-1]
ENSMUST00000121738; ENSMUSP00000113372; ENSMUSG00000001323 [Q9QZX7-1]
ENSMUST00000128556; ENSMUSP00000120012; ENSMUSG00000001323 [Q9QZX7-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		27364

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:27364

UCSC genome browser

More...UCSCi		uc007kcr.2, mouse [Q9QZX7-1]
uc011xzd.1, mouse [Q9QZX7-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF148321 mRNA Translation: AAF08701.1
AK031687 mRNA Translation: BAC27514.1
AK028034 mRNA Translation: BAC25712.1
AK043738 mRNA Translation: BAC31637.1
AK157122 mRNA Translation: BAE33968.1
AK170096 mRNA Translation: BAE41561.1
AL604066 Genomic DNA Translation: CAI24252.1
AL604066 Genomic DNA Translation: CAI24253.1
AL604066 Genomic DNA Translation: CAI24254.1
AL604066 Genomic DNA Translation: CAI24255.1 Sequence problems.
BC011164 mRNA Translation: AAH11164.1
AB232340 mRNA Translation: BAE19920.1
AB232341 mRNA Translation: BAE19921.1
AB232342 mRNA Translation: BAE19922.1
AB232343 mRNA Translation: BAE19923.1
AB235396 mRNA Translation: BAE44529.1
CCDSiCCDS25038.1 [Q9QZX7-1]
CCDS88190.1 [Q9QZX7-2]
RefSeqiNP_001156783.1, NM_001163311.1 [Q9QZX7-1]
NP_038789.1, NM_013761.4 [Q9QZX7-1]
XP_006533520.1, XM_006533457.3 [Q9QZX7-1]
XP_017170058.1, XM_017314569.1 [Q9QZX7-1]
XP_017170059.1, XM_017314570.1
XP_017170060.1, XM_017314571.1 [Q9QZX7-1]

3D structure databases

SMRiQ9QZX7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi205172, 9 interactors
MINTiQ9QZX7
STRINGi10090.ENSMUSP00000113372

Chemistry databases

BindingDBiQ9QZX7
ChEMBLiCHEMBL1075306

PTM databases

iPTMnetiQ9QZX7
PhosphoSitePlusiQ9QZX7
SwissPalmiQ9QZX7

Proteomic databases

jPOSTiQ9QZX7
PaxDbiQ9QZX7
PeptideAtlasiQ9QZX7
PRIDEiQ9QZX7
ProteomicsDBi257407 [Q9QZX7-1]
257408 [Q9QZX7-2]
257409 [Q9QZX7-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		4201, 310 antibodies

The DNASU plasmid repository

More...DNASUi		27364

Genome annotation databases

EnsembliENSMUST00000065211; ENSMUSP00000067552; ENSMUSG00000001323 [Q9QZX7-1]
ENSMUST00000108447; ENSMUSP00000104086; ENSMUSG00000001323 [Q9QZX7-2]
ENSMUST00000108448; ENSMUSP00000104087; ENSMUSG00000001323 [Q9QZX7-1]
ENSMUST00000121738; ENSMUSP00000113372; ENSMUSG00000001323 [Q9QZX7-1]
ENSMUST00000128556; ENSMUSP00000120012; ENSMUSG00000001323 [Q9QZX7-3]
GeneIDi27364
KEGGimmu:27364
UCSCiuc007kcr.2, mouse [Q9QZX7-1]
uc011xzd.1, mouse [Q9QZX7-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		63826
MGIiMGI:1351636, Srr
VEuPathDBiHostDB:ENSMUSG00000001323

Phylogenomic databases

eggNOGiKOG1251, Eukaryota
GeneTreeiENSGT00550000075026
HOGENOMiCLU_021152_4_2_1
InParanoidiQ9QZX7
OMAiLIHPFDH
OrthoDBi943371at2759
PhylomeDBiQ9QZX7
TreeFamiTF313346

Enzyme and pathway databases

BRENDAi4.3.1.17, 3474
5.1.1.18, 3474
ReactomeiR-MMU-977347, Serine biosynthesis

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		27364, 2 hits in 61 CRISPR screens

Protein Ontology

More...PROi		PR:Q9QZX7
RNActiQ9QZX7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000001323, Expressed in liver and 293 other tissues
ExpressionAtlasiQ9QZX7, baseline and differential
GenevisibleiQ9QZX7, MM

Family and domain databases

Gene3Di3.40.50.1100, 2 hits
InterProiView protein in InterPro
IPR001926, PLP-dep
IPR000634, Ser/Thr_deHydtase_PyrdxlP-BS
IPR036052, Trypto_synt_PLP_dependent
PfamiView protein in Pfam
PF00291, PALP, 1 hit
SUPFAMiSSF53686, SSF53686, 1 hit
PROSITEiView protein in PROSITE
PS00165, DEHYDRATASE_SER_THR, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSRR_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9QZX7
Secondary accession number(s): Q401M7
, Q5SWE4, Q5SWE5, Q5SWE7, Q8BT19, Q8CD11
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 31, 2002
Last sequence update: May 1, 2000
Last modified: September 29, 2021
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again