Srr

Functionⁱ

Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.5 Publications

Catalytic activityⁱ

L-serine = D-serine.4 Publications

D-serine = pyruvate + NH₃.1 Publication

L-serine = pyruvate + NH₃.3 Publications

Cofactorⁱ

pyridoxal 5'-phosphate2 Publications

Activity regulationⁱ

Allosterically activated by magnesium, and possibly also other divalent metal cations. Allosterically activated by ATP, ADP or GTP.2 Publications

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	51	ATPCurated	1
Active siteⁱ	56	Proton acceptorBy similarity	1
Active siteⁱ	84	Proton acceptorBy similarity	1
Binding siteⁱ	121	ATPBy similarity	1
Binding siteⁱ	135	SubstrateBy similarity	1
Metal bindingⁱ	210	MagnesiumBy similarity	1
Metal bindingⁱ	214	Magnesium; via carbonyl oxygenBy similarity	1
Metal bindingⁱ	216	MagnesiumBy similarity	1

GO - Molecular functionⁱ

ATP binding
Source: MGI
Inferred from direct assayⁱ
- 17293453
calcium ion binding
Source: MGI
Inferred from direct assayⁱ
- 12021263
D-serine ammonia-lyase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
glycine binding
Source: MGI
Inferred from direct assayⁱ
- 15710237
L-serine ammonia-lyase activity Source: MGI
magnesium ion binding Source: MGI
PDZ domain binding Source: MGI
protein homodimerization activity
Source: MGI
Inferred from direct assayⁱ
- 12021263
pyridoxal phosphate binding
Source: MGI
Inferred from mutant phenotypeⁱ
- 10557334
serine racemase activity
Source: MGI
Inferred from direct assayⁱ
threonine racemase activity
Source: MGI
Inferred from direct assayⁱ
- 15536068

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

aging
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
brain development
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
D-serine biosynthetic process
Source: MGI
Inferred from direct assayⁱ
D-serine metabolic process Source: MGI
L-serine metabolic process
Source: MGI
Inferred from direct assayⁱ
protein homotetramerization
Source: MGI
Inferred from direct assayⁱ
- 12021263
pyruvate biosynthetic process Source: MGI
response to lipopolysaccharide Source: Ensembl
response to morphine
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
serine family amino acid metabolic process
Source: MGI
Inferred from direct assayⁱ
- 15536068

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Allosteric enzyme, Isomerase, Lyase
Ligand	ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Pyridoxal phosphate

Enzyme and pathway databases

BRENDAⁱ	4.3.1.17 3474 5.1.1.18 3474
Reactomeⁱ	R-MMU-977347 Serine biosynthesis

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Serine racemase1 Publication (EC:5.1.1.184 Publications) Alternative name(s): D-serine ammonia-lyase D-serine dehydratase (EC:4.3.1.181 Publication) L-serine ammonia-lyase L-serine dehydratase (EC:4.3.1.173 Publications)
Gene namesⁱ	Name:Srr
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 11

Organism-specific databases

MGIⁱ	MGI:1351636 Srr

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Mutagenesisⁱ	51	K → A: Impairs ATP-binding inducing a 80% decrease in enzyme activity.		1
Mutagenesisⁱ	113	C → S: Abolishes S-nitrosylation. 1 Publication		1

Chemistry databases

ChEMBLⁱ	CHEMBL1075306

ChEMBLⁱ

CHEMBL1075306

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000185651	1 – 339	Serine racemaseAdd BLAST		339

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	56	N6-(pyridoxal phosphate)lysineBy similarity	1
Modified residueⁱ	71	PhosphothreonineCombined sources	1
Modified residueⁱ	113	S-nitrosocysteine1 Publication	1

Post-translational modificationⁱ

S-nitrosylated, leading to decrease the enzyme activity.1 Publication

Keywords - PTMⁱ

Phosphoprotein, S-nitrosylation

Proteomic databases

PaxDbⁱ	Q9QZX7
PeptideAtlas More...PeptideAtlasⁱ	Q9QZX7
PRIDEⁱ	Q9QZX7

PTM databases

iPTMnetⁱ	Q9QZX7
PhosphoSitePlusⁱ	Q9QZX7

Expressionⁱ

Tissue specificityⁱ

Detected in brain (at protein level). Brain.

Gene expression databases

Bgeeⁱ	ENSMUSG00000001323 Expressed in 268 organ(s), highest expression level in liver
CleanExⁱ	MM_SRR
ExpressionAtlasⁱ	Q9QZX7 baseline and differential
Genevisibleⁱ	Q9QZX7 MM

Interactionⁱ

Subunit structureⁱ

Homodimer.1 Publication

GO - Molecular functionⁱ

PDZ domain binding Source: MGI
protein homodimerization activity
Source: MGI
Inferred from direct assayⁱ
- 12021263

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	205172, 4 interactors
IntActⁱ	Q9QZX7, 2 interactors
Molecular INTeraction database More...MINTⁱ	Q9QZX7
STRINGⁱ	10090.ENSMUSP00000067552

Chemistry databases

BindingDBⁱ

Q9QZX7

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9QZX7
SMRⁱ	Q9QZX7
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	238 – 239	Substrate bindingBy similarity		2

Sequence similaritiesⁱ

Belongs to the serine/threonine dehydratase family.Curated

Phylogenomic databases

eggNOGⁱ	KOG1250 Eukaryota COG1171 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000075026
HOVERGENⁱ	HBG023167
InParanoidⁱ	Q9QZX7
KEGG Orthology (KO) More...KOⁱ	K12235
OMAⁱ	LIHPFDH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0FSJ
PhylomeDBⁱ	Q9QZX7
TreeFamⁱ	TF313346

Family and domain databases

InterProⁱ	View protein in InterPro IPR001926 PLP-dep IPR000634 Ser/Thr_deHydtase_PyrdxlP-BS IPR036052 Trypto_synt_PLP_dependent
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00291 PALP, 1 hit
SUPFAMⁱ	SSF53686 SSF53686, 1 hit
PROSITEⁱ	View protein in PROSITE PS00165 DEHYDRATASE_SER_THR, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9QZX7-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MCAQYCISFA DVEKAHINIQ DSIHLTPVLT SSILNQIAGR NLFFKCELFQ 
        60         70         80         90        100
KTGSFKIRGA LNAIRGLIPD TPEEKPKAVV THSSGNHGQA LTYAAKLEGI 
       110        120        130        140        150
PAYIVVPQTA PNCKKLAIQA YGASIVYCDP SDESREKVTQ RIMQETEGIL 
       160        170        180        190        200
VHPNQEPAVI AGQGTIALEV LNQVPLVDAL VVPVGGGGMV AGIAITIKAL 
       210        220        230        240        250
KPSVKVYAAE PSNADDCYQS KLKGELTPNL HPPETIADGV KSSIGLNTWP 
       260        270        280        290        300
IIRDLVDDVF TVTEDEIKYA TQLVWGRMKL LIEPTAGVAL AAVLSQHFQT 
       310        320        330 
VSPEVKNVCI VLSGGNVDLT SLNWVGQAER PAPYQTVSV

Length:339

Mass (Da):36,359

Last modified:May 1, 2000 - v1

Checksum:ⁱB9AE9A9336358728

GO

Isoform 2 (identifier: Q9QZX7-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
174-198: Missing.

« Hide

        10         20         30         40         50
MCAQYCISFA DVEKAHINIQ DSIHLTPVLT SSILNQIAGR NLFFKCELFQ 
        60         70         80         90        100
KTGSFKIRGA LNAIRGLIPD TPEEKPKAVV THSSGNHGQA LTYAAKLEGI 
       110        120        130        140        150
PAYIVVPQTA PNCKKLAIQA YGASIVYCDP SDESREKVTQ RIMQETEGIL 
       160        170        180        190        200
VHPNQEPAVI AGQGTIALEV LNQALKPSVK VYAAEPSNAD DCYQSKLKGE 
       210        220        230        240        250
LTPNLHPPET IADGVKSSIG LNTWPIIRDL VDDVFTVTED EIKYATQLVW 
       260        270        280        290        300
GRMKLLIEPT AGVALAAVLS QHFQTVSPEV KNVCIVLSGG NVDLTSLNWV 
       310 
GQAERPAPYQ TVSV

Show »

Length:314

Mass (Da):34,030

Checksum:ⁱ0BB6492649FF8491

GO

Isoform 3 (identifier: Q9QZX7-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
183-339: Missing.

« Hide

        10         20         30         40         50
MCAQYCISFA DVEKAHINIQ DSIHLTPVLT SSILNQIAGR NLFFKCELFQ 
        60         70         80         90        100
KTGSFKIRGA LNAIRGLIPD TPEEKPKAVV THSSGNHGQA LTYAAKLEGI 
       110        120        130        140        150
PAYIVVPQTA PNCKKLAIQA YGASIVYCDP SDESREKVTQ RIMQETEGIL 
       160        170        180 
VHPNQEPAVI AGQGTIALEV LNQVPLVDAL VV

Note: No experimental confirmation available.

Show »

Length:182

Mass (Da):19,694

Checksum:ⁱ23075946C01AF288

GO

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

A8Y5D6	A8Y5D6_MOUSE	Serine racemase Serine racemase	Srr	113	Annotation score:
Z4YMF3	Z4YMF3_MOUSE	Serine racemase Serine racemase	Srr	166	Annotation score:

Sequence cautionⁱ

The sequence CAI24255 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	111	P → T in BAC25712 (PubMed:16141072).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_025013	174 – 198	Missing in isoform 2. 1 PublicationAdd BLAST		25
Alternative sequenceⁱVSP_025014	183 – 339	Missing in isoform 3. CuratedAdd BLAST		157

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF148321 mRNA Translation: AAF08701.1 AK031687 mRNA Translation: BAC27514.1 AK028034 mRNA Translation: BAC25712.1 AK043738 mRNA Translation: BAC31637.1 AK157122 mRNA Translation: BAE33968.1 AK170096 mRNA Translation: BAE41561.1 AL604066 Genomic DNA Translation: CAI24252.1 AL604066 Genomic DNA Translation: CAI24253.1 AL604066 Genomic DNA Translation: CAI24254.1 AL604066 Genomic DNA Translation: CAI24255.1 Sequence problems. BC011164 mRNA Translation: AAH11164.1 AB232340 mRNA Translation: BAE19920.1 AB232341 mRNA Translation: BAE19921.1 AB232342 mRNA Translation: BAE19922.1 AB232343 mRNA Translation: BAE19923.1 AB235396 mRNA Translation: BAE44529.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS25038.1 [Q9QZX7-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001156783.1, NM_001163311.1 [Q9QZX7-1] NP_038789.1, NM_013761.4 [Q9QZX7-1] XP_006533520.1, XM_006533457.3 [Q9QZX7-1] XP_017170058.1, XM_017314569.1 [Q9QZX7-1] XP_017170059.1, XM_017314570.1 [Q9QZX7-1] XP_017170060.1, XM_017314571.1 [Q9QZX7-1]
UniGeneⁱ	Mm.131443 Mm.220843 Mm.412219

Genome annotation databases

Ensemblⁱ	ENSMUST00000065211; ENSMUSP00000067552; ENSMUSG00000001323 [Q9QZX7-1] ENSMUST00000108447; ENSMUSP00000104086; ENSMUSG00000001323 [Q9QZX7-2] ENSMUST00000108448; ENSMUSP00000104087; ENSMUSG00000001323 [Q9QZX7-1] ENSMUST00000121738; ENSMUSP00000113372; ENSMUSG00000001323 [Q9QZX7-1] ENSMUST00000128556; ENSMUSP00000120012; ENSMUSG00000001323 [Q9QZX7-3]
GeneIDⁱ	27364
KEGGⁱ	mmu:27364
UCSC genome browser More...UCSCⁱ	uc007kcr.2 mouse [Q9QZX7-1] uc011xzd.1 mouse [Q9QZX7-2]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Protein	Similar proteins		Species	Score	Length	Source
Q9QZX7	Isoform 3 of Serine racemase		MOUSE		182	UniRef100_Q9QZX7
Serine racemase (Fragment)		MOUSE		166
Serine racemase (Fragment)		MOUSE		113
UPI00001E5FBA		MOUSE		197

Protein	Similar proteins		Species	Score	Length	Source
Q9QZX7	Serine racemase	)	HUMAN		340	UniRef90_Q9GZT4
Uncharacterized protein		AOTNA		343
Uncharacterized protein		NOMLE		340
SRR isoform 6 (Fragment)		PONAB		78
SRR isoform 1 (Fragment)		PANTR		66
+55
Q9QZX7-2	serine racemase isoform X2		MESAU		314	UniRef90_Q9QZX7-2
Uncharacterized protein		ICTTR		314
UPI000A30643D		MUSPA		314

Protein	Similar proteins		Species	Score	Length	Source
Q9QZX7	Serine racemase	)	HUMAN		340	UniRef50_Q9GZT4
Serine racemase	)	RAT		333
Serine racemase		BOVIN		334
Uncharacterized protein		AOTNA		343
SRR isoform 2		PANTR		340
+274
Q9QZX7-2	serine racemase isoform X2		MESAU		314	UniRef50_Q9QZX7-2
Uncharacterized protein		ICTTR		314
Serine racemase (Fragment)		OPIHO		241
SRR		CEREH		305
Uncharacterized protein		ORNAN		237
+22

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF148321 mRNA Translation: AAF08701.1 AK031687 mRNA Translation: BAC27514.1 AK028034 mRNA Translation: BAC25712.1 AK043738 mRNA Translation: BAC31637.1 AK157122 mRNA Translation: BAE33968.1 AK170096 mRNA Translation: BAE41561.1 AL604066 Genomic DNA Translation: CAI24252.1 AL604066 Genomic DNA Translation: CAI24253.1 AL604066 Genomic DNA Translation: CAI24254.1 AL604066 Genomic DNA Translation: CAI24255.1 Sequence problems. BC011164 mRNA Translation: AAH11164.1 AB232340 mRNA Translation: BAE19920.1 AB232341 mRNA Translation: BAE19921.1 AB232342 mRNA Translation: BAE19922.1 AB232343 mRNA Translation: BAE19923.1 AB235396 mRNA Translation: BAE44529.1
CCDSⁱ	CCDS25038.1 [Q9QZX7-1]
RefSeqⁱ	NP_001156783.1, NM_001163311.1 [Q9QZX7-1] NP_038789.1, NM_013761.4 [Q9QZX7-1] XP_006533520.1, XM_006533457.3 [Q9QZX7-1] XP_017170058.1, XM_017314569.1 [Q9QZX7-1] XP_017170059.1, XM_017314570.1 [Q9QZX7-1] XP_017170060.1, XM_017314571.1 [Q9QZX7-1]
UniGeneⁱ	Mm.131443 Mm.220843 Mm.412219

3D structure databases

ProteinModelPortalⁱ	Q9QZX7
SMRⁱ	Q9QZX7
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	205172, 4 interactors
IntActⁱ	Q9QZX7, 2 interactors
MINTⁱ	Q9QZX7
STRINGⁱ	10090.ENSMUSP00000067552

Chemistry databases

BindingDBⁱ	Q9QZX7
ChEMBLⁱ	CHEMBL1075306

PTM databases

iPTMnetⁱ	Q9QZX7
PhosphoSitePlusⁱ	Q9QZX7

Proteomic databases

PaxDbⁱ	Q9QZX7
PeptideAtlasⁱ	Q9QZX7
PRIDEⁱ	Q9QZX7

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000065211; ENSMUSP00000067552; ENSMUSG00000001323 [Q9QZX7-1] ENSMUST00000108447; ENSMUSP00000104086; ENSMUSG00000001323 [Q9QZX7-2] ENSMUST00000108448; ENSMUSP00000104087; ENSMUSG00000001323 [Q9QZX7-1] ENSMUST00000121738; ENSMUSP00000113372; ENSMUSG00000001323 [Q9QZX7-1] ENSMUST00000128556; ENSMUSP00000120012; ENSMUSG00000001323 [Q9QZX7-3]
GeneIDⁱ	27364
KEGGⁱ	mmu:27364
UCSCⁱ	uc007kcr.2 mouse [Q9QZX7-1] uc011xzd.1 mouse [Q9QZX7-2]

Organism-specific databases

CTDⁱ	63826
MGIⁱ	MGI:1351636 Srr

Phylogenomic databases

eggNOGⁱ	KOG1250 Eukaryota COG1171 LUCA
GeneTreeⁱ	ENSGT00550000075026
HOVERGENⁱ	HBG023167
InParanoidⁱ	Q9QZX7
KOⁱ	K12235
OMAⁱ	LIHPFDH
OrthoDBⁱ	EOG091G0FSJ
PhylomeDBⁱ	Q9QZX7
TreeFamⁱ	TF313346

Enzyme and pathway databases

BRENDAⁱ	4.3.1.17 3474 5.1.1.18 3474
Reactomeⁱ	R-MMU-977347 Serine biosynthesis

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q9QZX7
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000001323 Expressed in 268 organ(s), highest expression level in liver
CleanExⁱ	MM_SRR
ExpressionAtlasⁱ	Q9QZX7 baseline and differential
Genevisibleⁱ	Q9QZX7 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR001926 PLP-dep IPR000634 Ser/Thr_deHydtase_PyrdxlP-BS IPR036052 Trypto_synt_PLP_dependent
Pfamⁱ	View protein in Pfam PF00291 PALP, 1 hit
SUPFAMⁱ	SSF53686 SSF53686, 1 hit
PROSITEⁱ	View protein in PROSITE PS00165 DEHYDRATASE_SER_THR, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SRR_MOUSE
Accessionⁱ	Q9QZX7Primary (citable) accession number: Q9QZX7 Secondary accession number(s): Q401M7 , Q5SWE4, Q5SWE5, Q5SWE7, Q8BT19, Q8CD11
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 31, 2002
	Last sequence update:	May 1, 2000
	Last modified:	November 7, 2018
	This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

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Annotation systems

Supporting data

UniProtKB - Q9QZX7 (SRR_MOUSE)

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Serine racemase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma Membrane

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ