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Entry version 106 (18 Sep 2019)
Sequence version 1 (01 May 2000)
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Protein

PDZ domain-containing protein 2

Gene

Pdzd2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PDZ domain-containing protein 2
Alternative name(s):
PDZ domain-containing protein 3
Plakophilin-related armadillo repeat protein-interacting PDZ protein
Cleaved into the following chain:
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pdzd2
Synonyms:Papin, Pdzk3, Pin1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...
RGDi
619958 Pdzd2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cytoplasm, Endoplasmic reticulum, Nucleus, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi2402 – 2411DLDKLCNGED → I: Loss of proteolytic cleavage. 10
Mutagenesisi2402D → A: Loss of proteolytic cleavage. 1 Publication1
Mutagenesisi2404D → A: No loss of proteolytic cleavage. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000582951 – 2766PDZ domain-containing protein 2Add BLAST2766
ChainiPRO_0000302757?2403 – 2766Processed PDZ domain-containing protein 2Add BLAST364

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei517PhosphoserineCombined sources1
Modified residuei891PhosphoserineCombined sources1
Modified residuei895PhosphoserineCombined sources1
Modified residuei1767PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

A secreted form is produced by caspase-mediated proteolytic cleavage.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei2402 – 2403Cleavage; by caspases2

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9QZR8

PRoteomics IDEntifications database

More...
PRIDEi
Q9QZR8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9QZR8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9QZR8

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9QZR8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the heart, liver, brain, spleen, lung, kidney, testis and skeletal muscle.2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SCN10A, CTNND2 and PKP4.

2 Publications

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9QZR8, 2 interactors

Molecular INTeraction database

More...
MINTi
Q9QZR8

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000017937

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9QZR8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini85 – 177PDZ 1PROSITE-ProRule annotationAdd BLAST93
Domaini334 – 419PDZ 2PROSITE-ProRule annotationAdd BLAST86
Domaini535 – 621PDZ 3PROSITE-ProRule annotationAdd BLAST87
Domaini679 – 764PDZ 4PROSITE-ProRule annotationAdd BLAST86
Domaini2550 – 2634PDZ 5PROSITE-ProRule annotationAdd BLAST85
Domaini2678 – 2763PDZ 6PROSITE-ProRule annotationAdd BLAST86

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2271 – 2390Ser-richAdd BLAST120

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3528 Eukaryota
ENOG4110362 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000115486

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9QZR8

Database of Orthologous Groups

More...
OrthoDBi
225688at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9QZR8

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00595 PDZ, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228 PDZ, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106 PDZ, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9QZR8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPITQDNALL HLPLLYEWLQ NSLREGGDSP EQRLCQAAIQ KLQEYIQLNL
60 70 80 90 100
AVDESTVPPD HSPPEMEICT VYLTKQLGDT ETVGLSFGNI PVFGDYGEKR
110 120 130 140 150
RGGKKRKTHQ GPVLDVGCIW VTELRKNSPA GKSGKVRLRD EILSLNGQLM
160 170 180 190 200
VGVDVTGASY LAEQCWNGGF IYLIMLRRFK QKAHVTYNGN SGNSSEPGET
210 220 230 240 250
PTLELGDQTS KKGKRTRKFG VISRPSISKT PEDSKSSSGC DTADDPNSEL
260 270 280 290 300
ENGADPELGN GHAFELENGP HSLKDVAGPH LERSEADSEV ELRVPKTEAP
310 320 330 340 350
LSDSNDKRRF SKTGKTDFQS SDCLAREEVG RIWKMELLKE SDGLGIQVSG
360 370 380 390 400
GRGSKRSPHA IVVTQVKEGG AAHRDGRLSL GDELLVINGH LLVGLSHEEA
410 420 430 440 450
VAILRSATGM VQLVVASKMP GSEESQDVGS SEESKGNLES PKQGNCKTKL
460 470 480 490 500
KSRLSGGVHR LESVEEYNEL MVRNGDPRIR MLEVSRDGRK HSLPQLLDST
510 520 530 540 550
GTSQEYHIVK KSTRSLSTTH VESPWRLIRP SVISIIGLYK EKGKGLGFSI
560 570 580 590 600
AGGRDCIRGQ MGIFVKTIFP NGSAAEDGRL KEGDEILDVN GIPIKGLTFQ
610 620 630 640 650
EAIHTFKQIR SGLFVLTVRT KLLSPSLTPC STPTHMSRSS SPSFNTNSGG
660 670 680 690 700
TPAGGGQEEG GSSSLGRKAP GPKDRIVMEV TLNKEPRVGL GIGACCLALE
710 720 730 740 750
NSPPGIYIHS LAPGSVAKME SNLSRGDQIL EVNSVNVRHA ALSKVHAILS
760 770 780 790 800
KCPPGPVRLV IGRHPNPKVS EQEMDEVIAR STYQESREAN SSPGLGTPLK
810 820 830 840 850
SPSLAKKDSL LSESELSQYF VHDGQGSLSD FVVAGSEDED HPGSGYETSE
860 870 880 890 900
DGSLLPVPSA HKARANSLVT LGSQRTSGLL HKQVTVARQA SLPGSPQVLR
910 920 930 940 950
NPLLRQRRVR CYDSNGGSDD EDFDGEGDCI SLPGVLPGPG KPLVEDDTRP
960 970 980 990 1000
ALTTSSKSID VNKQEERLQK PLVSKACSVP LLGSSLDSEH SILNGAGGTP
1010 1020 1030 1040 1050
PKVASLPGSG ETPKNGPRGS GRKEMSGSRS SPKLEYRVPT DTQSPRSPEN
1060 1070 1080 1090 1100
HTSPPQKSEN LVSRHKPVAR ISPHYKRSDA EEAPGGTANG PCAQDLKVQA
1110 1120 1130 1140 1150
SPVKDPVTSR QPGGTAEKEL RGNPTPGDSS VPTNCGPAST PCHPNIGLPT
1160 1170 1180 1190 1200
ENPQGAAPEC GPHPGTGWDG SSEHLCSPGK SREVHPDSSE TPTVAEQVHQ
1210 1220 1230 1240 1250
PESLSQPVSP RTSEPESQGI SKMKPPSQRC VSPREKASTP PDSSRAWAAP
1260 1270 1280 1290 1300
GDSSPSTRRI AVPMSTGAAP ATAIPQASLV SQERSRGLSG PSKGLGTKEL
1310 1320 1330 1340 1350
CIPKSLKDGA LLEDTAPASG KMSHASSPSG PVATERTLSG SPENPVTDID
1360 1370 1380 1390 1400
NFIEEASEAR LSQSPQKADC RAHGDTFESQ PPGGAGSSSS HHAQMVRSDQ
1410 1420 1430 1440 1450
TSSPRKTGGT GSPPPQQWAL QPSVLDSIHP DKHLAVNKTF LNNYSRNFSN
1460 1470 1480 1490 1500
FHEDSISLSG PGGSSEPSPS SMYGNAEDSS SDPESLAEDP GAAARNNWSP
1510 1520 1530 1540 1550
PLSPESSPKE GSSESEDERI EICSTDGCPG TPVTAPPPTQ VALCPVLPVQ
1560 1570 1580 1590 1600
QRAVCKPVGD ICERACFVPG ASRTSIPDSS QPFSFLDVSS EEPETWASIN
1610 1620 1630 1640 1650
ASQNHMPVCT EGIMDVTSTS SNMGDSQSSQ MTRHCRNAPF VLGNPDMVND
1660 1670 1680 1690 1700
LGRDLLDEGA PKEGAAAASV MRSVFALGAE GPKNGEAVLA DLHIAERGNL
1710 1720 1730 1740 1750
EDLLQKPKTI SRRPILTWFK EINKDSQGSH LRSTSEKEQS SMLALGPGSK
1760 1770 1780 1790 1800
ANMVNTGHRK GVTVPKSPPS RQKSQENKDL PPKSPVETLG NCQKPKCSPK
1810 1820 1830 1840 1850
LKRLNSKGKA SPEVPVAIST KGSRNDHRKT LPSPQASHKM FSKAVSHRLH
1860 1870 1880 1890 1900
IADQEEPKNT AGDTPKPPQC VPESKPPQAA LGSLRTSASD TSIRTFTSPL
1910 1920 1930 1940 1950
TSPKLLPEQG ANSRFHMAVY LESDTSCPTT SRSPRSGPEG KAPHANSGSA
1960 1970 1980 1990 2000
SPPASRASLA LAGIRQSKQF TPGRADLLVS EATQPQGICE KGAEKKVSDP
2010 2020 2030 2040 2050
PQRTNQLKIV EISSERVPKN ACGDRPPESD RKGGFLTQNN CQEKSAIRLR
2060 2070 2080 2090 2100
QSEESSPEHT PFPPSQASQV EREIRWSFSM AKPATSSSSS LQLPAKLPES
2110 2120 2130 2140 2150
FQGKSSQMPA SVGVPKNGVP IGLAGEESPY FTPRPATRTY SMPAQFSSHF
2160 2170 2180 2190 2200
GREGPSPHSP SHSPQDPQVP AMGGKLSEKT AKGVTNGQGV YSVKPLLETS
2210 2220 2230 2240 2250
KNLSPVDGRD VSADPETSCL IPDKVKVTRR QYCCEQSWPH ESTSFFSVKQ
2260 2270 2280 2290 2300
RIKSFENLAN SDRPTAKCAT SPFLSVSSKP PINRRSSGSI PSGSPSDMTS
2310 2320 2330 2340 2350
RSLRRSLSSC SESQSEASSL LPQMTKSPSS MTLTVSRQNP PDTSNKGPSP
2360 2370 2380 2390 2400
DPKKSLVPVG IPTSTVSPAS PSKRNKSSVR HAQPSPVSRS KLQERRTLSM
2410 2420 2430 2440 2450
PDLDKLCNGE DDSASPGAVL FKTQLEITPR RSKGSQATSP AGSPARGHAD
2460 2470 2480 2490 2500
FNGSTFLSCP MNGGTRAYTK GNSPPASEPA IATGSREEGE SVWATPSGKS
2510 2520 2530 2540 2550
WSVSLDRLLA SVGNQQRLQG ILSLVGSKSP ILTLIQEAKA QSETKEDICF
2560 2570 2580 2590 2600
IVLNKKEGSG LGFSVAGGAD VEPKSVMVHR VFSQGVASQE GTVSRGDFLL
2610 2620 2630 2640 2650
SVNGTSLAGL AHSEVTKVLH QAELHKHALM IIKKGNDQPG PSFKQEPPSA
2660 2670 2680 2690 2700
NGKGPFPRRT LPLEPGAGRN GAAHDALCVE VLKTSAGLGL SLDGGKSSVS
2710 2720 2730 2740 2750
GEGPLVIKRV YKGGAAERAG TIEAGDEILA INGKPLVGLV HFDAWNIMKS
2760
VPEGPVQLVI RKHRDS
Length:2,766
Mass (Da):293,890
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1DC34DF7B4A6D1DD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1M785F1M785_RAT
PDZ domain-containing protein 2
Pdzd2
2,762Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF169411 mRNA Translation: AAD55940.1

NCBI Reference Sequences

More...
RefSeqi
NP_075229.1, NM_022940.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
65034

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:65034

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF169411 mRNA Translation: AAD55940.1
RefSeqiNP_075229.1, NM_022940.1

3D structure databases

SMRiQ9QZR8
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9QZR8, 2 interactors
MINTiQ9QZR8
STRINGi10116.ENSRNOP00000017937

PTM databases

iPTMnetiQ9QZR8
PhosphoSitePlusiQ9QZR8
SwissPalmiQ9QZR8

Proteomic databases

PaxDbiQ9QZR8
PRIDEiQ9QZR8

Genome annotation databases

GeneIDi65034
KEGGirno:65034

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23037
RGDi619958 Pdzd2

Phylogenomic databases

eggNOGiKOG3528 Eukaryota
ENOG4110362 LUCA
HOGENOMiHOG000115486
InParanoidiQ9QZR8
OrthoDBi225688at2759
PhylomeDBiQ9QZR8

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9QZR8

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF00595 PDZ, 5 hits
SMARTiView protein in SMART
SM00228 PDZ, 6 hits
SUPFAMiSSF50156 SSF50156, 6 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPDZD2_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9QZR8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: May 1, 2000
Last modified: September 18, 2019
This is version 106 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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