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Entry version 138 (10 Apr 2019)
Sequence version 2 (21 Feb 2006)
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Protein

Interferon-inducible GTPase 1

Gene

Iigp1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

GTPase with low activity. Has higher affinity for GDP than for GTP. Plays a role in resistance to intracellular pathogens. Required for disruption of the parasitophorous vacuole formed following T.gondii infection and subsequent killing of the parasite. Mediates resistance to C.trachomatis infection by targeting bacterial inclusions to autophagosomes for subsequent lysosomal destruction.4 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi77 – 84GTP1 Publication8
Nucleotide bindingi102 – 106GTP1 Publication5
Nucleotide bindingi184 – 186GTP1 Publication3
Nucleotide bindingi231 – 233GTP1 Publication3

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processImmunity, Innate immunity
LigandGTP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Interferon-inducible GTPase 1 (EC:3.6.5.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Iigp1
Synonyms:Irga6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1926259 Iigp1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi2G → A: Protein is detected exclusively in the aqueous phase. 1 Publication1
Mutagenesisi82K → A: Constitutively active. Binds GTP but fails to hydrolyze it. Does not localize to the parasitophorous vacuole membrane following T.gondii infection. 2 Publications1
Mutagenesisi83S → N: Abrogates interaction with HOOK3. Greatly reduces binding affinity for GDP and GTP. Abolishes GTP-dependent oligomer formation. 2 Publications1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCurated
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002235272 – 413Interferon-inducible GTPase 1Add BLAST412

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi2N-myristoyl glycineCurated1

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9QZ85

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9QZ85

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9QZ85

PRoteomics IDEntifications database

More...
PRIDEi
Q9QZ85

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9QZ85

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9QZ85

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9QZ85

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by IFNG, IFNA1 and lipopolysaccharide (LPS) within 20 hours. Transiently up-regulated during the early stages of infection by Listeria monocytogenes. After 6 days expression is back to basal levels.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000054072 Expressed in 235 organ(s), highest expression level in liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9QZ85 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9QZ85 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer, as apoenzyme and in the GDP-bound form. Homooligomer, upon GTP binding. Interacts with HOOK3.3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
208563, 1 interactor

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9QZ85

Database of interacting proteins

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DIPi
DIP-58958N

Protein interaction database and analysis system

More...
IntActi
Q9QZ85, 5 interactors

Molecular INTeraction database

More...
MINTi
Q9QZ85

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000032473

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1413
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TPZX-ray2.00A/B1-411[»]
1TQ2X-ray2.70A/B1-411[»]
1TQ4X-ray1.95A1-413[»]
1TQ6X-ray2.70A1-413[»]
1TQDX-ray2.30A/B1-413[»]
4LV5X-ray1.70B1-413[»]
4LV8X-ray1.72B1-413[»]
5FPHX-ray3.20A/B/C/D/E/F/G1-413[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9QZ85

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9QZ85

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9QZ85

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini68 – 250IRG-type GAdd BLAST183

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J4GH Eukaryota
ENOG41125KF LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183007

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000220822

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG054304

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9QZ85

Identification of Orthologs from Complete Genome Data

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OMAi
MIRENCK

Database of Orthologous Groups

More...
OrthoDBi
688334at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9QZ85

TreeFam database of animal gene trees

More...
TreeFami
TF331897

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030385 G_IRG_dom
IPR007743 Immunity-related_GTPase-like
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05049 IIGP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51716 G_IRG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9QZ85-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGQLFSSPKS DENNDLPSSF TGYFKKFNTG RKIISQEILN LIELRMRKGN
60 70 80 90 100
IQLTNSAISD ALKEIDSSVL NVAVTGETGS GKSSFINTLR GIGNEEEGAA
110 120 130 140 150
KTGVVEVTME RHPYKHPNIP NVVFWDLPGI GSTNFPPNTY LEKMKFYEYD
160 170 180 190 200
FFIIISATRF KKNDIDIAKA ISMMKKEFYF VRTKVDSDIT NEADGKPQTF
210 220 230 240 250
DKEKVLQDIR LNCVNTFREN GIAEPPIFLL SNKNVCHYDF PVLMDKLISD
260 270 280 290 300
LPIYKRHNFM VSLPNITDSV IEKKRQFLKQ RIWLEGFAAD LVNIIPSLTF
310 320 330 340 350
LLDSDLETLK KSMKFYRTVF GVDETSLQRL ARDWEIEVDQ VEAMIKSPAV
360 370 380 390 400
FKPTDEETIQ ERLSRYIQEF CLANGYLLPK NSFLKEIFYL KYYFLDMVTE
410
DAKTLLKEIC LRN
Length:413
Mass (Da):47,572
Last modified:February 21, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44B5A95FCA58A37A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti138N → D in AAF07195 (PubMed:11907101).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ007971 mRNA Translation: CAA07798.1
AF194871 mRNA Translation: AAF07195.1
AK153060 mRNA Translation: BAE31686.1
CT010300 mRNA Translation: CAJ18508.1
BC004649 mRNA Translation: AAH04649.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS29270.1

NCBI Reference Sequences

More...
RefSeqi
NP_001139747.1, NM_001146275.1
NP_068564.4, NM_021792.4
XP_011245279.1, XM_011246977.2
XP_011245280.1, XM_011246978.2
XP_011245281.1, XM_011246979.2
XP_011245282.1, XM_011246980.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.261140

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000032473; ENSMUSP00000032473; ENSMUSG00000054072
ENSMUST00000066912; ENSMUSP00000063390; ENSMUSG00000054072

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
60440

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:60440

UCSC genome browser

More...
UCSCi
uc008fac.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ007971 mRNA Translation: CAA07798.1
AF194871 mRNA Translation: AAF07195.1
AK153060 mRNA Translation: BAE31686.1
CT010300 mRNA Translation: CAJ18508.1
BC004649 mRNA Translation: AAH04649.1
CCDSiCCDS29270.1
RefSeqiNP_001139747.1, NM_001146275.1
NP_068564.4, NM_021792.4
XP_011245279.1, XM_011246977.2
XP_011245280.1, XM_011246978.2
XP_011245281.1, XM_011246979.2
XP_011245282.1, XM_011246980.1
UniGeneiMm.261140

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TPZX-ray2.00A/B1-411[»]
1TQ2X-ray2.70A/B1-411[»]
1TQ4X-ray1.95A1-413[»]
1TQ6X-ray2.70A1-413[»]
1TQDX-ray2.30A/B1-413[»]
4LV5X-ray1.70B1-413[»]
4LV8X-ray1.72B1-413[»]
5FPHX-ray3.20A/B/C/D/E/F/G1-413[»]
ProteinModelPortaliQ9QZ85
SMRiQ9QZ85
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi208563, 1 interactor
CORUMiQ9QZ85
DIPiDIP-58958N
IntActiQ9QZ85, 5 interactors
MINTiQ9QZ85
STRINGi10090.ENSMUSP00000032473

PTM databases

iPTMnetiQ9QZ85
PhosphoSitePlusiQ9QZ85
SwissPalmiQ9QZ85

Proteomic databases

EPDiQ9QZ85
jPOSTiQ9QZ85
PaxDbiQ9QZ85
PRIDEiQ9QZ85

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
60440
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000032473; ENSMUSP00000032473; ENSMUSG00000054072
ENSMUST00000066912; ENSMUSP00000063390; ENSMUSG00000054072
GeneIDi60440
KEGGimmu:60440
UCSCiuc008fac.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
60440
MGIiMGI:1926259 Iigp1

Phylogenomic databases

eggNOGiENOG410J4GH Eukaryota
ENOG41125KF LUCA
GeneTreeiENSGT00950000183007
HOGENOMiHOG000220822
HOVERGENiHBG054304
InParanoidiQ9QZ85
OMAiMIRENCK
OrthoDBi688334at2759
PhylomeDBiQ9QZ85
TreeFamiTF331897

Miscellaneous databases

EvolutionaryTraceiQ9QZ85

Protein Ontology

More...
PROi
PR:Q9QZ85

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000054072 Expressed in 235 organ(s), highest expression level in liver
ExpressionAtlasiQ9QZ85 baseline and differential
GenevisibleiQ9QZ85 MM

Family and domain databases

InterProiView protein in InterPro
IPR030385 G_IRG_dom
IPR007743 Immunity-related_GTPase-like
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF05049 IIGP, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51716 G_IRG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIIGP1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9QZ85
Secondary accession number(s): Q9Z1M3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: February 21, 2006
Last modified: April 10, 2019
This is version 138 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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