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Protein

Myoglobin

Gene

Mb

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi65Iron (heme distal ligand)1
Metal bindingi94Iron (heme proximal ligand)1

GO - Molecular functioni

  • heme binding Source: RGD
  • metal ion binding Source: UniProtKB-KW
  • oxygen binding Source: RGD
  • oxygen carrier activity Source: UniProtKB-KW

GO - Biological processi

  • brown fat cell differentiation Source: Ensembl
  • enucleate erythrocyte differentiation Source: Ensembl
  • heart development Source: Ensembl
  • oxygen transport Source: RGD
  • response to hormone Source: RGD
  • response to hydrogen peroxide Source: RGD
  • response to hypoxia Source: Ensembl
  • slow-twitch skeletal muscle fiber contraction Source: RGD

Keywordsi

Molecular functionMuscle protein
Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-RNO-8981607 Intracellular oxygen transport

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:Mb
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi620411 Mb

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000533411 – 154MyoglobinAdd BLAST154

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei4PhosphoserineCombined sources1
Modified residuei32PhosphoserineCombined sources1
Modified residuei68PhosphothreonineBy similarity1
Modified residuei121PhosphoserineCombined sources1
Modified residuei133PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9QZ76
PRIDEiQ9QZ76

PTM databases

iPTMnetiQ9QZ76
PhosphoSitePlusiQ9QZ76

Expressioni

Gene expression databases

BgeeiENSRNOG00000004583
GenevisibleiQ9QZ76 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006184

Structurei

3D structure databases

ProteinModelPortaliQ9QZ76
SMRiQ9QZ76
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3378 Eukaryota
COG1018 LUCA
GeneTreeiENSGT00730000110844
HOGENOMiHOG000070111
HOVERGENiHBG107340
InParanoidiQ9QZ76
KOiK21892
OMAiLFRNDIA
OrthoDBiEOG091G0OAO
PhylomeDBiQ9QZ76
TreeFamiTF332967

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002335 Myoglobin
PANTHERiPTHR11442:SF5 PTHR11442:SF5, 1 hit
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00613 MYOGLOBIN
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q9QZ76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDGEWQM VLNIWGKVEG DLAGHGQEVL ISLFKAHPET LEKFDKFKNL
60 70 80 90 100
KSEEEMKSSE DLKKHGCTVL TALGTILKKK GQHAAEIQPL AQSHATKHKI
110 120 130 140 150
PVKYLEFISE VIIQVLKKRY SGDFGADAQG AMSKALELFR NDIAAKYKEL

GFQG
Length:154
Mass (Da):17,157
Last modified:January 23, 2007 - v3
Checksum:i98B31BE57FA020DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF197916 mRNA Translation: AAF05848.1
BC070511 mRNA Translation: AAH70511.1
RefSeqiNP_067599.1, NM_021588.2
UniGeneiRn.40511

Genome annotation databases

EnsembliENSRNOT00000006184; ENSRNOP00000006184; ENSRNOG00000004583
GeneIDi59108
KEGGirno:59108
UCSCiRGD:620411 rat

Similar proteinsi

Entry informationi

Entry nameiMYG_RAT
AccessioniPrimary (citable) accession number: Q9QZ76
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 117 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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