Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Pecanex-like protein 1

Gene

Pcnx1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Pecanex-like protein 1
Alternative name(s):
Pecanex homolog protein 1By similarity
Gene namesi
Name:Pcnx1By similarity
Synonyms:Kiaa0805, Pcnx, Pcnxl1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1891924 Pcnx

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalSequence analysisAdd BLAST21
Transmembranei57 – 77HelicalSequence analysisAdd BLAST21
Transmembranei1010 – 1030HelicalSequence analysisAdd BLAST21
Transmembranei1035 – 1055HelicalSequence analysisAdd BLAST21
Transmembranei1069 – 1089HelicalSequence analysisAdd BLAST21
Transmembranei1119 – 1139HelicalSequence analysisAdd BLAST21
Transmembranei1163 – 1183HelicalSequence analysisAdd BLAST21
Transmembranei1196 – 1216HelicalSequence analysisAdd BLAST21
Transmembranei1269 – 1289HelicalSequence analysisAdd BLAST21
Transmembranei1297 – 1317HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002157941 – 2344Pecanex-like protein 1Add BLAST2344

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi1094N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1158N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1582N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1723N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1985N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2075N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2231N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2237N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2263N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9QYC1
PeptideAtlasiQ9QYC1
PRIDEiQ9QYC1

PTM databases

iPTMnetiQ9QYC1
PhosphoSitePlusiQ9QYC1

Expressioni

Gene expression databases

BgeeiENSMUSG00000021140 Expressed in 269 organ(s), highest expression level in choroid plexus epithelium
CleanExiMM_PCNX
ExpressionAtlasiQ9QYC1 baseline and differential
GenevisibleiQ9QYC1 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021567

Structurei

3D structure databases

ProteinModelPortaliQ9QYC1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi320 – 417Ser-richAdd BLAST98
Compositional biasi573 – 638Ser-richAdd BLAST66
Compositional biasi2106 – 2202Ser-richAdd BLAST97

Sequence similaritiesi

Belongs to the pecanex family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3604 Eukaryota
ENOG410XPRI LUCA
GeneTreeiENSGT00390000013164
HOGENOMiHOG000007773
HOVERGENiHBG045627
InParanoidiQ9QYC1
OrthoDBiEOG091G007W
PhylomeDBiQ9QYC1
TreeFamiTF313570

Family and domain databases

InterProiView protein in InterPro
IPR039797 Pecanex
IPR007735 Pecanex_C
PANTHERiPTHR12372 PTHR12372, 4 hits
PfamiView protein in Pfam
PF05041 Pecanex_C, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9QYC1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGSQTLQILR QGVWAALSGG WYYDPHQATF VNALHLYLWL FLLGLPFTLY
60 70 80 90 100
MALPSSMIIV AVYCPVVAAV FIILKMVNYR LHRALDAGEI VDRSAKEFTD
110 120 130 140 150
QRAKAEQGNC STRRKDSNGP SDPGGGIEMS EFIREATPPV GCSSRNSYAG
160 170 180 190 200
LDPSNQIGSG SSRLGTAATI KGDTDTAKTS DDISLSLGQS SSLCKEGSEE
210 220 230 240 250
QDLATDRKLF RLVSNDSFIS IQPSLSSCGQ DLPRDFSDKV SLPSHSQHHR
260 270 280 290 300
VDQSLCSACD TEVASLVPLH SHSYRKEHRP RGVPRTSSSA VAFPDASLSG
310 320 330 340 350
LPLYQQQQRR GLDPVTELDS SKPHSGTRES SAGKSCPPAQ SQPAADRRKS
360 370 380 390 400
SSQPPTKCGK SRALNAEKSV DSLRSLSTRS SGSTESYCSG TDRDTNSTLS
410 420 430 440 450
SYKSEQTSST HIESILSEHE ESPKVGDKSA RKRECGADSV EERSHRADDR
460 470 480 490 500
RTSSDKTAPE GNTPAGPPEA PDAQASEEMA DQAAPSSSAS EDANKNPHAN
510 520 530 540 550
EFTVPGDRPP EQSAESKEEQ SEKPSLATDS RVCKDDGGKQ KEGDVRPKSS
560 570 580 590 600
SLIHRTTSAH KPGRRRTGKK RASSFDSSRH RDYVSFRGVS GTKPHSAVFG
610 620 630 640 650
HDEDSSDQSD LSRAPSIHSA HQFSSDSSSS ATSHSCQSPE GKYGALKTKH
660 670 680 690 700
GHRDRGTDSD HTHRAHPGPE GTTKKRASRR TSSTSSAKTR ARVLSLDSGT
710 720 730 740 750
VACLNDSNRL LAPDSMKPLT TSKSDLEAKE GEVLDELSLL GRASQLETVT
760 770 780 790 800
RSRNSLPSQV AFPEGEEQDA ATGAAQASEE AVAFRRERST FRRQAVRRRH
810 820 830 840 850
NAGSNPTPPT LLIGSPLSLQ DGQQGQQSTA QVKVQSRPPS QAAVLSASAS
860 870 880 890 900
LLVRKGSVHL EASHDHASAV GGSSLHDELG KFSSTLYETG GCDMSLVNFE
910 920 930 940 950
PAARRASNIC DTDSHVSSST SVRFYPHDML SLPQIRLNRL LTIDTDLLEQ
960 970 980 990 1000
QDIDLSPDLA ATYGPTEEAA QKVKHYYRFW VLPQLWIGIN FDRLTLLALF
1010 1020 1030 1040 1050
DRNREILENI LAVVLAILVA FLGSILLIQG FFRDIWVFQF CLVIASCQYS
1060 1070 1080 1090 1100
LLKSVQPDSS SPRHGHNRII AYSRPVYFCL CCGLIWLLDY GSRNLTTSKF
1110 1120 1130 1140 1150
KLYGVTFTNP LVLLSARDLV IVFTLCFPIV FFIGLLPQVN TFVMYLCEQL
1160 1170 1180 1190 1200
DIHIFGGNAT TSLLAALYSF LCSIVAVALL YGLCYGALRD SWDGQHVPVL
1210 1220 1230 1240 1250
FSVFCGLLVA VSYHLSRQSS DPSVLFSLMQ SKIFPKADEK NPEDPLSEVK
1260 1270 1280 1290 1300
DPLPEKLSNS VSERLQSDLV VCVIIGVLYF AIHVSTVFTA LQPALKYVLY
1310 1320 1330 1340 1350
ALVGVVGLVT HYVLPQVRKQ LPWHCFSRPL LRTAEHSQYE VRNAATMMWF
1360 1370 1380 1390 1400
EKLHVWLLFV EKNIIYPLIV LNELSSSAET IASPKKLDTE LGALMITIAG
1410 1420 1430 1440 1450
LKLLRSSFSS PTYQYITVIF TVLFFKFDYE AFSETMLLDL FFMSILFSKL
1460 1470 1480 1490 1500
WELLYKLQFV YTYVAPWQIT WGSAFHAFAQ PFAVPHSAML FVQAIVSAFF
1510 1520 1530 1540 1550
STPLNPFLGS AIFITSYVRP VKFWERDYNT KRVDHSNTRL ASQLDRNPGS
1560 1570 1580 1590 1600
DDNNLNSIFY EHLTRSLQHS LCGDLLLGRW GNYSTGDCFI LASDYLNALV
1610 1620 1630 1640 1650
HLIEIGNGLV TFQLRGLEFR GTYCQQREVE AITEGVEEDE GFCCCEPGHV
1660 1670 1680 1690 1700
PHVLSFNAAF GQRWLAWEVV VTKYILEGYS ITDNSAASML QVFDLRRVLT
1710 1720 1730 1740 1750
TYYVKGIIYY VTTSSKLEEW LANETMQEGL RLCADRNYVD VDPTFNPNID
1760 1770 1780 1790 1800
EDYDHRLAGI SRESFCVIYL SWIEYCSSRR AKPLDVDKDS SLVTLCYGLC
1810 1820 1830 1840 1850
VLGRRALGTA SHHMSSNLES FLYGLHALFK GDFRISSVRD EWIFADMELL
1860 1870 1880 1890 1900
RKVVVPGIRM SIKLHQDHFT SPDEYDDPTV LYEAIVSHEK NLVIAHEGDP
1910 1920 1930 1940 1950
AWRSAVLANS PSLLALRHVM DDGTNEYKII MLNRRYLSFR VIKVNKECVR
1960 1970 1980 1990 2000
GLWAGQQQEL VFLRNRNPER GSIQNAKQAL RNMINSSCDQ PIGYPIFVSP
2010 2020 2030 2040 2050
LTTSYSDSHD QLKEILGGPI SLGNIRNFIV STWHRLRKGC GAGCNSGGNI
2060 2070 2080 2090 2100
EDSDTGGGTS CPGNSAVTAS DPHNNVSQGS TGHPGQGAGS GLHPPTTSYP
2110 2120 2130 2140 2150
PTLGTSHSAH SVQSSLVRQS PARASMASQS SYCYSSRHSS LRMSTTGFVP
2160 2170 2180 2190 2200
CRRSSTSQIS LRNLPSSIQS RLSMVNQMEA ASQGGMGCVQ HGLPSSSSSS
2210 2220 2230 2240 2250
QSIPACKHHT LVAFLGAEGG QGSATEAQPG NTSSPANISH ARKGEVIYRV
2260 2270 2280 2290 2300
QIVDLSQILE GINVSKRKEL HWPDEGIRLK AGRNSWKDWS PQEGMEGHVV
2310 2320 2330 2340
HRWVPCSRDP STRSHIDKTV LLVQIDDKYV TIIETGVLEL GAEV
Length:2,344
Mass (Da):258,147
Last modified:January 9, 2007 - v3
Checksum:iFF3E3C60D57488CB
GO
Isoform 2 (identifier: Q9QYC1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     854-945: Missing.

Note: No experimental confirmation available.
Show »
Length:2,252
Mass (Da):248,162
Checksum:i970A28422B905E70
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VKR5A0A1Y7VKR5_MOUSE
Pecanex homolog
Pcnx
2,338Annotation score:
A0A1Y7VLV8A0A1Y7VLV8_MOUSE
Pecanex homolog
Pcnx
1,473Annotation score:
A0A1Y7VJ77A0A1Y7VJ77_MOUSE
Pecanex homolog
Pcnx
818Annotation score:
A0A1Y7VLG1A0A1Y7VLG1_MOUSE
Pecanex homolog
Pcnx
75Annotation score:

Sequence cautioni

The sequence AAF21809 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti930 – 934Missing in AAF21809 (Ref. 3) Curated5
Sequence conflicti1220S → N in AAF21809 (Ref. 3) Curated1
Sequence conflicti1457L → R in AAF21809 (Ref. 3) Curated1
Sequence conflicti1806A → T in BAB29314 (PubMed:16141072).Curated1
Sequence conflicti1874E → K in BAB29314 (PubMed:16141072).Curated1
Sequence conflicti1899D → Y in BAB29314 (PubMed:16141072).Curated1
Sequence conflicti2318K → N in AAF21809 (Ref. 3) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_022167854 – 945Missing in isoform 2. 1 PublicationAdd BLAST92

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124484 Genomic DNA No translation available.
AC124595 Genomic DNA No translation available.
AK129221 mRNA Translation: BAC98031.3
AF096286 mRNA Translation: AAF21809.1 Different initiation.
AK014387 mRNA Translation: BAB29314.1
CCDSiCCDS26025.1 [Q9QYC1-1]
RefSeqiNP_061284.2, NM_018814.3 [Q9QYC1-1]
UniGeneiMm.86584

Genome annotation databases

EnsembliENSMUST00000021567; ENSMUSP00000021567; ENSMUSG00000021140 [Q9QYC1-1]
GeneIDi54604
KEGGimmu:54604
UCSCiuc007ocq.1 mouse [Q9QYC1-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124484 Genomic DNA No translation available.
AC124595 Genomic DNA No translation available.
AK129221 mRNA Translation: BAC98031.3
AF096286 mRNA Translation: AAF21809.1 Different initiation.
AK014387 mRNA Translation: BAB29314.1
CCDSiCCDS26025.1 [Q9QYC1-1]
RefSeqiNP_061284.2, NM_018814.3 [Q9QYC1-1]
UniGeneiMm.86584

3D structure databases

ProteinModelPortaliQ9QYC1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021567

PTM databases

iPTMnetiQ9QYC1
PhosphoSitePlusiQ9QYC1

Proteomic databases

PaxDbiQ9QYC1
PeptideAtlasiQ9QYC1
PRIDEiQ9QYC1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021567; ENSMUSP00000021567; ENSMUSG00000021140 [Q9QYC1-1]
GeneIDi54604
KEGGimmu:54604
UCSCiuc007ocq.1 mouse [Q9QYC1-1]

Organism-specific databases

CTDi54604
MGIiMGI:1891924 Pcnx
RougeiSearch...

Phylogenomic databases

eggNOGiKOG3604 Eukaryota
ENOG410XPRI LUCA
GeneTreeiENSGT00390000013164
HOGENOMiHOG000007773
HOVERGENiHBG045627
InParanoidiQ9QYC1
OrthoDBiEOG091G007W
PhylomeDBiQ9QYC1
TreeFamiTF313570

Miscellaneous databases

PROiPR:Q9QYC1
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021140 Expressed in 269 organ(s), highest expression level in choroid plexus epithelium
CleanExiMM_PCNX
ExpressionAtlasiQ9QYC1 baseline and differential
GenevisibleiQ9QYC1 MM

Family and domain databases

InterProiView protein in InterPro
IPR039797 Pecanex
IPR007735 Pecanex_C
PANTHERiPTHR12372 PTHR12372, 4 hits
PfamiView protein in Pfam
PF05041 Pecanex_C, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPCX1_MOUSE
AccessioniPrimary (citable) accession number: Q9QYC1
Secondary accession number(s): Q6ZQ41, Q9CUU7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2003
Last sequence update: January 9, 2007
Last modified: November 7, 2018
This is version 104 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again