UniProtKB - Q9QYC0 (ADDA_MOUSE)

BLAST

>sp|Q9QYC0|ADDA_MOUSE Alpha-adducin OS=Mus musculus OX=10090 GN=Add1 PE=1 SV=2
MNGDTRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTASVPNVYPAAPQGGMAALNMS
LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
LIVPFGLLYSEVTASSLVKVNLQGDIVDRGSTNLGVNQAGFTLHSAVYAARPDAKCIVHI
HTPAGAAVSAMKCGLLPISPEALSLGDVAYHDYHGILVDEEEKILIQKNLGPKSKVLILR
NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLDPGKYKAKSRSPGTPA
GEGSGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALRERSKKYSDVEVPASVTGHS
FASDGDSGTCSPLRHSFQKQQREKTRWLHSGRGDDASEEGQNGSSPKSKTKWTKEDGHRT
STSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVMMDRSLVQGELVT
ASKAIIEKEYQPHVIVSTTGPNPFNTLTDRELEEYRREVERKQKGSEENLDETREQKEKS
PPDQSAVPNTPPSTPVKLEEDLPQEPTSRDDSDATTFKPTPPDLSPDEPSEALAFPAVEE
EAHASPDPTQPPAEADPEPASAPTPGAEEVASPATEEGSPMDPGSDGSPGKSPSKKKKKF
RTPSFLKKSKKKSDS

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History
Entry version 150 (12 Sep 2018)
Sequence version 2 (01 Dec 2000)
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Protein

Alpha-adducin

Gene

Add1

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.

GO - Molecular functionⁱ

actin filament binding Source: MGI
calmodulin binding Source: UniProtKB-KW
protein heterodimerization activity Source: MGI
protein homodimerization activity Source: MGI
spectrin binding Source: MGI
structural molecule activity
Source: MGI
Inferred from direct assayⁱ
- 10485892
T cell receptor binding Source: MGI
transcription factor binding Source: MGI

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

actin filament bundle assembly Source: MGI
barbed-end actin filament capping Source: MGI
cell morphogenesis
Source: MGI
Inferred from mutant phenotypeⁱ
- 18723693
cellular response to calcium ion
Source: CAFA
Inferred from direct assayⁱ
- 25978380
cellular response to retinoic acid Source: MGI
cell volume homeostasis
Source: MGI
Inferred from mutant phenotypeⁱ
- 18723693
erythrocyte differentiation
Source: MGI
Inferred from mutant phenotypeⁱ
- 18723693
hemoglobin metabolic process
Source: MGI
Inferred from mutant phenotypeⁱ
- 18723693
homeostasis of number of cells within a tissue
Source: MGI
Inferred from mutant phenotypeⁱ
- 18723693
in utero embryonic development
Source: MGI
Inferred from mutant phenotypeⁱ
- 18723693
multicellular organism growth
Source: MGI
Inferred from mutant phenotypeⁱ
- 18723693
negative regulation of actin filament polymerization Source: MGI
positive regulation of adherens junction organization
Source: CAFA
Inferred from mutant phenotypeⁱ
- 25978380
positive regulation of angiogenesis Source: MGI
positive regulation of endocytosis Source: MGI
positive regulation of establishment of endothelial barrier
Source: CAFA
Inferred from mutant phenotypeⁱ
- 25978380
positive regulation of protein binding Source: MGI

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Actin-binding, Calmodulin-binding

Molecular function

Actin-binding, Calmodulin-binding

Enzyme and pathway databases

Reactomeⁱ	R-MMU-264870 Caspase-mediated cleavage of cytoskeletal proteins R-MMU-5223345 Miscellaneous transport and binding events

Reactomeⁱ

R-MMU-264870 Caspase-mediated cleavage of cytoskeletal proteins
R-MMU-5223345 Miscellaneous transport and binding events

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Alpha-adducin Alternative name(s): Erythrocyte adducin subunit alpha
Gene namesⁱ	Name:Add1
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 5

Organism-specific databases

MGIⁱ	MGI:87918 Add1

Keywords - Cellular componentⁱ

Cell membrane, Cytoplasm, Cytoskeleton, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000218531	1 – 735	Alpha-adducinAdd BLAST		735

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	1	N-acetylmethionineBy similarity	1
Modified residueⁱ	12	PhosphoserineBy similarity	1
Modified residueⁱ	59	PhosphoserineCombined sources	1
Modified residueⁱ	64	PhosphoserineBy similarity	1
Modified residueⁱ	331	PhosphothreonineBy similarity	1
Modified residueⁱ	334	PhosphoserineBy similarity	1
Modified residueⁱ	353	PhosphoserineBy similarity	1
Modified residueⁱ	355	PhosphoserineCombined sources	1
Modified residueⁱ	358	PhosphothreonineCombined sources	1
Modified residueⁱ	364	PhosphoserineCombined sources	1
Modified residueⁱ	366	PhosphoserineCombined sources	1
Modified residueⁱ	408	PhosphoserineCombined sources	1
Modified residueⁱ	427	PhosphoserineCombined sources	1
Modified residueⁱ	429	PhosphothreonineCombined sources	1
Modified residueⁱ	431	PhosphoserineCombined sources	1
Modified residueⁱ	436	PhosphoserineCombined sources	1
Modified residueⁱ	445	Phosphothreonine; by ROCK2By similarity	1
Modified residueⁱ	464	PhosphoserineCombined sources	1
Modified residueⁱ	465	PhosphoserineCombined sources	1
Modified residueⁱ	480	Phosphothreonine; by ROCK2By similarity	1
Modified residueⁱ	481	Phosphoserine; by PKABy similarity	1
Modified residueⁱ	586	PhosphoserineCombined sources	1
Modified residueⁱ	600	PhosphoserineCombined sources	1
Modified residueⁱ	605	PhosphoserineCombined sources	1
Modified residueⁱ	610	PhosphothreonineCombined sources	1
Modified residueⁱ	613	PhosphoserineCombined sources	1
Modified residueⁱ	614	PhosphothreonineCombined sources	1
Modified residueⁱ	705	PhosphoserineBy similarity	1
Modified residueⁱ	708	PhosphoserineBy similarity	1
Modified residueⁱ	712	PhosphoserineBy similarity	1
Modified residueⁱ	714	Phosphoserine; by PKCBy similarity	1
Modified residueⁱ	724	Phosphoserine; by PKA and PKCBy similarity	1
Isoform 2 (identifier: Q9QYC0-2)
Modified residueⁱ	600	PhosphoserineCombined sources	1
Modified residueⁱ	605	PhosphoserineCombined sources	1
Modified residueⁱ	610	PhosphothreonineCombined sources	1
Modified residueⁱ	613	PhosphoserineCombined sources	1
Modified residueⁱ	614	PhosphothreonineCombined sources	1

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

EPDⁱ	Q9QYC0
PaxDbⁱ	Q9QYC0
PeptideAtlas More...PeptideAtlasⁱ	Q9QYC0
PRIDEⁱ	Q9QYC0

PTM databases

iPTMnetⁱ	Q9QYC0
PhosphoSitePlusⁱ	Q9QYC0
SwissPalmⁱ	Q9QYC0

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000029106 Expressed in 287 organ(s), highest expression level in blood
CleanExⁱ	MM_ADD1
ExpressionAtlasⁱ	Q9QYC0 baseline and differential
Genevisibleⁱ	Q9QYC0 MM

Interactionⁱ

Subunit structureⁱ

Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit.

GO - Molecular functionⁱ

actin filament binding Source: MGI
calmodulin binding Source: UniProtKB-KW
protein heterodimerization activity Source: MGI
protein homodimerization activity Source: MGI
spectrin binding Source: MGI
T cell receptor binding Source: MGI
transcription factor binding Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	197981, 9 interactors
IntActⁱ	Q9QYC0, 7 interactors
Molecular INTeraction database More...MINTⁱ	Q9QYC0
STRINGⁱ	10090.ENSMUSP00000109979

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9QYC0
SMRⁱ	Q9QYC0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	715 – 732	Interaction with calmodulinSequence analysisAdd BLAST		18

Domainⁱ

Each subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region.

Sequence similaritiesⁱ

Belongs to the aldolase class II family. Adducin subfamily.Curated

Phylogenomic databases

eggNOGⁱ	KOG3699 Eukaryota COG0235 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000016462
HOGENOMⁱ	HOG000116349
HOVERGENⁱ	HBG004180
InParanoidⁱ	Q9QYC0
KEGG Orthology (KO) More...KOⁱ	K18622
OMAⁱ	SFQKQQR
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0324
PhylomeDBⁱ	Q9QYC0
TreeFamⁱ	TF313003

Family and domain databases

Gene3Dⁱ	3.40.225.10, 1 hit
InterProⁱ	View protein in InterPro IPR027766 ADD1 IPR001303 Aldolase_II/adducin_N IPR036409 Aldolase_II/adducin_N_sf
PANTHERⁱ	PTHR10672:SF4 PTHR10672:SF4, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00596 Aldolase_II, 1 hit
SMARTⁱ	View protein in SMART SM01007 Aldolase_II, 1 hit
SUPFAMⁱ	SSF53639 SSF53639, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

Note: Additional isoforms seem to exist.

This entry has 2 described isoforms and 7 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9QYC0-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNGDTRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN 
        60         70         80         90        100
MMEQKKRVSM ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTA 
       110        120        130        140        150
SVPNVYPAAP QGGMAALNMS LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA 
       160        170        180        190        200
AFYRLADLFG WSQLIYNHIT TRVNSEQEHF LIVPFGLLYS EVTASSLVKV 
       210        220        230        240        250
NLQGDIVDRG STNLGVNQAG FTLHSAVYAA RPDAKCIVHI HTPAGAAVSA 
       260        270        280        290        300
MKCGLLPISP EALSLGDVAY HDYHGILVDE EEKILIQKNL GPKSKVLILR 
       310        320        330        340        350
NHGLVSVGES VEEAFYYIHN LVVACEIQVR TLASAGGPDN LVLLDPGKYK 
       360        370        380        390        400
AKSRSPGTPA GEGSGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL 
       410        420        430        440        450
RERSKKYSDV EVPASVTGHS FASDGDSGTC SPLRHSFQKQ QREKTRWLHS 
       460        470        480        490        500
GRGDDASEEG QNGSSPKSKT KWTKEDGHRT STSAVPNLFV PLNTNPKEVQ 
       510        520        530        540        550
EMRNKIREQN LQDIKTAGPQ SQVLCGVMMD RSLVQGELVT ASKAIIEKEY 
       560        570        580        590        600
QPHVIVSTTG PNPFNTLTDR ELEEYRREVE RKQKGSEENL DETREQKEKS 
       610        620        630        640        650
PPDQSAVPNT PPSTPVKLEE DLPQEPTSRD DSDATTFKPT PPDLSPDEPS 
       660        670        680        690        700
EALAFPAVEE EAHASPDPTQ PPAEADPEPA SAPTPGAEEV ASPATEEGSP 
       710        720        730 
MDPGSDGSPG KSPSKKKKKF RTPSFLKKSK KKSDS

Length:735

Mass (Da):80,647

Last modified:December 1, 2000 - v2

Checksum:ⁱE6AAA7F6273A33DD

Isoform 2 (identifier: Q9QYC0-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
621-632: DLPQEPTSRDDS → AGDGCAKEYLLP
633-735: Missing.

« Hide

        10         20         30         40         50
MNGDTRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN 
        60         70         80         90        100
MMEQKKRVSM ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTA 
       110        120        130        140        150
SVPNVYPAAP QGGMAALNMS LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA 
       160        170        180        190        200
AFYRLADLFG WSQLIYNHIT TRVNSEQEHF LIVPFGLLYS EVTASSLVKV 
       210        220        230        240        250
NLQGDIVDRG STNLGVNQAG FTLHSAVYAA RPDAKCIVHI HTPAGAAVSA 
       260        270        280        290        300
MKCGLLPISP EALSLGDVAY HDYHGILVDE EEKILIQKNL GPKSKVLILR 
       310        320        330        340        350
NHGLVSVGES VEEAFYYIHN LVVACEIQVR TLASAGGPDN LVLLDPGKYK 
       360        370        380        390        400
AKSRSPGTPA GEGSGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL 
       410        420        430        440        450
RERSKKYSDV EVPASVTGHS FASDGDSGTC SPLRHSFQKQ QREKTRWLHS 
       460        470        480        490        500
GRGDDASEEG QNGSSPKSKT KWTKEDGHRT STSAVPNLFV PLNTNPKEVQ 
       510        520        530        540        550
EMRNKIREQN LQDIKTAGPQ SQVLCGVMMD RSLVQGELVT ASKAIIEKEY 
       560        570        580        590        600
QPHVIVSTTG PNPFNTLTDR ELEEYRREVE RKQKGSEENL DETREQKEKS 
       610        620        630 
PPDQSAVPNT PPSTPVKLEE AGDGCAKEYL LP

Show »

Length:632

Mass (Da):69,887

Checksum:ⁱEA5ED051D13C6B38

Computationally mapped potential isoform sequencesⁱ

There are 7 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

F8WGR0	F8WGR0_MOUSE	Alpha-adducin Alpha-adducin	Add1	663	Annotation score:
E9Q1K3	E9Q1K3_MOUSE	Alpha-adducin Alpha-adducin	Add1	660	Annotation score:
F8WHZ9	F8WHZ9_MOUSE	Alpha-adducin Alpha-adducin	Add1	662	Annotation score:
F6RDR0	F6RDR0_MOUSE	Alpha-adducin Alpha-adducin	Add1	160	Annotation score:
A0A0J9YVI4	A0A0J9YVI4_MOUSE	Alpha-adducin Alpha-adducin	Add1	248	Annotation score:
F6V4G5	F6V4G5_MOUSE	Alpha-adducin Alpha-adducin	Add1	135	Annotation score:
D3Z0T1	D3Z0T1_MOUSE	Alpha-adducin Alpha-adducin	Add1	141	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	234	A → T in AAF29504 (PubMed:10845937).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_000177	621 – 632	DLPQE…SRDDS → AGDGCAKEYLLP in isoform 2. CuratedAdd BLAST		12
Alternative sequenceⁱVSP_000178	633 – 735	Missing in isoform 2. CuratedAdd BLAST		103

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF096839 mRNA Translation: AAF24971.1 AF189771 mRNA Translation: AAF29504.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS19216.1 [Q9QYC0-1] CCDS39069.1 [Q9QYC0-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001019629.2, NM_001024458.4 [Q9QYC0-1] NP_001095914.1, NM_001102444.2 NP_001318009.1, NM_001331080.1 [Q9QYC0-1] NP_001318016.1, NM_001331087.1 [Q9QYC0-2] NP_038485.1, NM_013457.4 [Q9QYC0-2] XP_017176104.1, XM_017320615.1 [Q9QYC0-2]
UniGeneⁱ	Mm.289106

Genome annotation databases

Ensemblⁱ	ENSMUST00000114338; ENSMUSP00000109977; ENSMUSG00000029106 [Q9QYC0-2] ENSMUST00000114340; ENSMUSP00000109979; ENSMUSG00000029106 [Q9QYC0-1]
GeneIDⁱ	11518
KEGGⁱ	mmu:11518
UCSC genome browser More...UCSCⁱ	uc008xcp.1 mouse [Q9QYC0-2] uc008xcr.1 mouse [Q9QYC0-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9QYC0	Alpha-adducin		HUMAN		737	UniRef90_P35611
Alpha-adducin		PONAB		737
Alpha-adducin		RAT		735
Adducin 1		MUSPF		775
alpha-adducin isoform X3		DELLE		754
+110

Protein	Similar proteins		Species	Score	Length	Source
Q9QYC0	Alpha-adducin		HUMAN		737	UniRef50_P35611
Alpha-adducin		PONAB		737
Alpha-adducin		RAT		735
Adducin 1		MUSPF		775
alpha-adducin isoform X3		DELLE		754
+1449

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF096839 mRNA Translation: AAF24971.1 AF189771 mRNA Translation: AAF29504.1
CCDSⁱ	CCDS19216.1 [Q9QYC0-1] CCDS39069.1 [Q9QYC0-2]
RefSeqⁱ	NP_001019629.2, NM_001024458.4 [Q9QYC0-1] NP_001095914.1, NM_001102444.2 NP_001318009.1, NM_001331080.1 [Q9QYC0-1] NP_001318016.1, NM_001331087.1 [Q9QYC0-2] NP_038485.1, NM_013457.4 [Q9QYC0-2] XP_017176104.1, XM_017320615.1 [Q9QYC0-2]
UniGeneⁱ	Mm.289106

3D structure databases

ProteinModelPortalⁱ	Q9QYC0
SMRⁱ	Q9QYC0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	197981, 9 interactors
IntActⁱ	Q9QYC0, 7 interactors
MINTⁱ	Q9QYC0
STRINGⁱ	10090.ENSMUSP00000109979

PTM databases

iPTMnetⁱ	Q9QYC0
PhosphoSitePlusⁱ	Q9QYC0
SwissPalmⁱ	Q9QYC0

Proteomic databases

EPDⁱ	Q9QYC0
PaxDbⁱ	Q9QYC0
PeptideAtlasⁱ	Q9QYC0
PRIDEⁱ	Q9QYC0

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000114338; ENSMUSP00000109977; ENSMUSG00000029106 [Q9QYC0-2] ENSMUST00000114340; ENSMUSP00000109979; ENSMUSG00000029106 [Q9QYC0-1]
GeneIDⁱ	11518
KEGGⁱ	mmu:11518
UCSCⁱ	uc008xcp.1 mouse [Q9QYC0-2] uc008xcr.1 mouse [Q9QYC0-1]

Organism-specific databases

CTDⁱ	118
MGIⁱ	MGI:87918 Add1

Phylogenomic databases

eggNOGⁱ	KOG3699 Eukaryota COG0235 LUCA
GeneTreeⁱ	ENSGT00390000016462
HOGENOMⁱ	HOG000116349
HOVERGENⁱ	HBG004180
InParanoidⁱ	Q9QYC0
KOⁱ	K18622
OMAⁱ	SFQKQQR
OrthoDBⁱ	EOG091G0324
PhylomeDBⁱ	Q9QYC0
TreeFamⁱ	TF313003

Enzyme and pathway databases

Reactomeⁱ	R-MMU-264870 Caspase-mediated cleavage of cytoskeletal proteins R-MMU-5223345 Miscellaneous transport and binding events

Reactomeⁱ

R-MMU-264870 Caspase-mediated cleavage of cytoskeletal proteins
R-MMU-5223345 Miscellaneous transport and binding events

Miscellaneous databases

ChiTaRSⁱ	Add1 mouse
Protein Ontology More...PROⁱ	PR:Q9QYC0
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000029106 Expressed in 287 organ(s), highest expression level in blood
CleanExⁱ	MM_ADD1
ExpressionAtlasⁱ	Q9QYC0 baseline and differential
Genevisibleⁱ	Q9QYC0 MM

Family and domain databases

Gene3Dⁱ	3.40.225.10, 1 hit
InterProⁱ	View protein in InterPro IPR027766 ADD1 IPR001303 Aldolase_II/adducin_N IPR036409 Aldolase_II/adducin_N_sf
PANTHERⁱ	PTHR10672:SF4 PTHR10672:SF4, 1 hit
Pfamⁱ	View protein in Pfam PF00596 Aldolase_II, 1 hit
SMARTⁱ	View protein in SMART SM01007 Aldolase_II, 1 hit
SUPFAMⁱ	SSF53639 SSF53639, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ADDA_MOUSE
Accessionⁱ	Q9QYC0Primary (citable) accession number: Q9QYC0 Secondary accession number(s): Q9JLE3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
	Last sequence update:	December 1, 2000
	Last modified:	September 12, 2018
	This is version 150 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9QYC0 (ADDA_MOUSE)

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Alpha-adducin

Add1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytoskeleton

Plasma membrane

Cytoskeleton

Nucleus

Plasma Membrane

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ