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Entry version 126 (16 Oct 2019)
Sequence version 2 (16 May 2006)
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Protein

Nuclear pore membrane glycoprotein 210

Gene

Nup210

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-159227 Transport of the SLBP independent Mature mRNA
R-MMU-159230 Transport of the SLBP Dependant Mature mRNA
R-MMU-159231 Transport of Mature mRNA Derived from an Intronless Transcript
R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-191859 snRNP Assembly
R-MMU-3108214 SUMOylation of DNA damage response and repair proteins
R-MMU-3301854 Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453 Regulation of HSF1-mediated heat shock response
R-MMU-4615885 SUMOylation of DNA replication proteins

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nuclear pore membrane glycoprotein 210
Short name:
Nuclear pore protein gp210
Alternative name(s):
Nuclear envelope pore membrane protein POM 210
Short name:
POM210
Nucleoporin Nup210
Pore membrane protein of 210 kDa
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nup210
Synonyms:Kiaa0906
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1859555 Nup210

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini27 – 1808Perinuclear spaceCuratedAdd BLAST1782
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1809 – 1829HelicalSequence analysisAdd BLAST21
Topological domaini1830 – 1886CytoplasmicCuratedAdd BLAST57

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Nuclear pore complex, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26By similarityAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000023604727 – 1886Nuclear pore membrane glycoprotein 210Add BLAST1860

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi44N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi337N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi405N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi484N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi681N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi801N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi926N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1039N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1116N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1135N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1362N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1441N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1839PhosphoserineCombined sources1
Modified residuei1844PhosphothreonineCombined sources1
Modified residuei1873PhosphoserineCombined sources1
Modified residuei1876PhosphoserineBy similarity1
Modified residuei1880PhosphoserineBy similarity1
Modified residuei1885PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides (By similarity).By similarity
Phosphorylated at Ser-1880 in mitosis specifically; not phosphorylated in interphase.By similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9QY81

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9QY81

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9QY81

PeptideAtlas

More...
PeptideAtlasi
Q9QY81

PRoteomics IDEntifications database

More...
PRIDEi
Q9QY81

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2567

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9QY81

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9QY81

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9QY81

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Preferential expressed in epithelial cells. In the kidney, expression was seen in both the epithelium derived from the ureteric tree and the mesenchyme-derived epithelium. In other tissues of 13-day-old embryos, expression was also confined to the epithelium. In nervous tissues, mainly expressed in the olfactory epithelium and walls of the lateral ventricle. Weak expression was seen in the heart.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000030091 Expressed in 261 organ(s), highest expression level in bone marrow

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9QY81 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9QY81 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms dimers and possibly higher-order oligomers.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
207678, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q9QY81, 2 interactors

Molecular INTeraction database

More...
MINTi
Q9QY81

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000032179

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9QY81

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1078 – 1151BIG2Sequence analysisAdd BLAST74

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi486 – 492Poly-Ser7

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NUP210 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1833 Eukaryota
ENOG410XNNU LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000009491

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000115312

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9QY81

KEGG Orthology (KO)

More...
KOi
K14314

Identification of Orthologs from Complete Genome Data

More...
OMAi
DIICFDS

Database of Orthologous Groups

More...
OrthoDBi
843414at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9QY81

TreeFam database of animal gene trees

More...
TreeFami
TF313331

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003343 Big_2
IPR008964 Invasin/intimin_cell_adhesion

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02368 Big_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00635 BID_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49373 SSF49373, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9QY81-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARASLVQPA LWALLLLQVV GPAAAAKLNI PKVLLPFTRA TRVNFTLEAS
60 70 80 90 100
EGCYRWSSTR PEVASIEPLG SSEQQCSQKA VVQARLTQPA RLTSIIFAED
110 120 130 140 150
ITTGQVLRCD AIVDLIHGIQ IVSTTRELYL EDSPLELKIQ ALDSEGNTFS
160 170 180 190 200
TLAGLVFDWT IVKDTEANGF SDSHNALRIL TFLESTYIPP SYISEMEKAA
210 220 230 240 250
KQGDTILVSG MKTGSSKLKA RIQEAVYKNV RPAEVRLLIL ENILLNPAYD
260 270 280 290 300
VYLLVGTSIH YKVQKIRQGK ITELSMPSDQ YELQLQNSIP DPQGDPARPV
310 320 330 340 350
AILTQDTSRV TAMQMGQSNL VLGHRSIRMQ GASRLPNSTI YVVEAGYLGF
360 370 380 390 400
TVYPGDRWVL ETGHLYAITI EVFDRSSNKV YPSDNIRIEA VLPAEFFEVL
410 420 430 440 450
SSSQNGSYHH IRAIQSGQTA ISATLTSVVD QDGGVHVLQV PVWNQQEVDI
460 470 480 490 500
HIPITLYPSI LTFPWQPKTG AYQYTIKAHG GSGNFSWSSS SSMVATVTVK
510 520 530 540 550
GVMTTSGDTG LSVIRAHDVQ NPLHFGEMKV YVIEPSSMEF APCQVEARVG
560 570 580 590 600
HTLELPLTIS GFMPGGGSEV VTLSDCSHFD LVVEVENQGV FQPLPGRLPP
610 620 630 640 650
GPEHCSGVKV KADAQGSTTL LVSYTHGHVH LDAKITLAAY LPLKAVDPSS
660 670 680 690 700
VAVVTLGSSK EMLFEGGPRP WVLEPSKFFR NVTSEDTGSI SLSLLGPPAS
710 720 730 740 750
RNYQQHRVLM TCQALGEQVI ALSVGNRPSL SNPFPAVEPT VVKSICAPPS
760 770 780 790 800
RLTLMPVYAL PQLDLSCPLL QQNKQVVPVS SHRNPLLDLG AYDQQGRRFD
810 820 830 840 850
NFSSLSIQWE SSRPLLASIE LDQPMQLVSQ DDGNGQKKLH GLQTVSVHEA
860 870 880 890 900
SGTTAISATA TGYQQSHLSE ARVKQPHDPL VPVSASIELI LVEDVRVSPE
910 920 930 940 950
EMTIYNHPGV QVELYITEGS GYFFLNTSTQ DIIKVAYQDT RGVALVHPLL
960 970 980 990 1000
PGSSTVMVHD LCLAFPAPAK AIIHVSDIQE LYVRVVDKVE IGKAVKAYVR
1010 1020 1030 1040 1050
VLDFYKKPFL AKYFTFMDLK LQAASQIITL VTLDEALDNY TATFLVHGVA
1060 1070 1080 1090 1100
IGQTSLSASV TDKSGQRVSS TPQQIEVFPP FRLIPRKVTL IIGAMMQITS
1110 1120 1130 1140 1150
EGGPQPQSNI LFSINNESVA AVSSSGLVRG LMVGNGSVLG VVQAVDAETG
1160 1170 1180 1190 1200
KVIIVSQDLV EVEVLQLQAV RIRAPITRMR TGTQMPVFVT GITSNQSPFS
1210 1220 1230 1240 1250
FGNAVPGLTF HWSVTKRDVL DLRGRHHEVS IRLPPQYNFA MNVYGRVKGR
1260 1270 1280 1290 1300
TGLRVVVKAL DPTAGQLHGL GKELSDEIQI QVFEKLRLLN PEIEAEQILM
1310 1320 1330 1340 1350
SPNSFIKLQT NRDGAAILSY RVLDGPEKAP IVHTDEKGFL VSGSGIGVST
1360 1370 1380 1390 1400
LEVIAQEPFG TNQTILVAVK VSPVSYLRIS MSPVLHTQHK EALTALPLGM
1410 1420 1430 1440 1450
TVTFIVHFHD SSGDIFHAHN SVLNFATNRD DFVQIGKGAT NNTCIIRTVS
1460 1470 1480 1490 1500
VGLTLLHVWD VEHLGLSDFV PLPVLQAITP ELSGAVVVGD ILCLASVLTS
1510 1520 1530 1540 1550
LGGVSGTWSS SASHVLYVDP KTGVAIARDA GSVTVYYEIA GQLKTFKEIV
1560 1570 1580 1590 1600
VGTPQKIVAR RLHSAQTSIQ EATASKVTVS VGDRSSNLLG ECSPAQREAI
1610 1620 1630 1640 1650
EALHPESLIS CQLQFKQDVF DFPACDVFTV EPGFDAALGQ YLCSVTMRRL
1660 1670 1680 1690 1700
TDKQLKHLNM KKTSLAVTAS IPSSYTSVEK VGAEVPFSPG LYANQAEILL
1710 1720 1730 1740 1750
SNHYTSSEVK VFGAVESLEN LEVKSGSPAV LAFVKEKSFG LPSFITYTVG
1760 1770 1780 1790 1800
VLDPTAGSQG PLSTALTFSS PATNQAITIP VTVAFVLDRR GPGPYGASLL
1810 1820 1830 1840 1850
SHFLDSYQVM FFTFFALLAG TAVTIIAYHT VCAPRELASP LALTPRASPQ
1860 1870 1880
HSPHYLASSP AAFNTLPSGR KASPPSGLWS PAYASH
Length:1,886
Mass (Da):204,101
Last modified:May 16, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8732FBAA46096862
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4J1I6A0A0R4J1I6_MOUSE
Nuclear pore membrane glycoprotein ...
Nup210
1,842Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6XGN0F6XGN0_MOUSE
Nuclear pore membrane glycoprotein ...
Nup210
1,076Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti14L → V in AAF21969 (PubMed:10469352).Curated1
Sequence conflicti37F → G in AAF21969 (PubMed:10469352).Curated1
Sequence conflicti107 – 108LR → VA in AAF21969 (PubMed:10469352).Curated2
Sequence conflicti420A → S in AAF21969 (PubMed:10469352).Curated1
Sequence conflicti425L → F in BAE34024 (PubMed:16141072).Curated1
Sequence conflicti512 – 513SV → RE in AAF21969 (PubMed:10469352).Curated2
Sequence conflicti517 – 518HD → QH in AAF21969 (PubMed:10469352).Curated2
Sequence conflicti597R → K in AAF21969 (PubMed:10469352).Curated1
Sequence conflicti719 – 762Missing (PubMed:15489334).CuratedAdd BLAST44
Sequence conflicti808Q → E in BAE34024 (PubMed:16141072).Curated1
Sequence conflicti812 – 814SRP → FPR in AAF21969 (PubMed:10469352).Curated3
Sequence conflicti904I → V in BAE34024 (PubMed:16141072).Curated1
Sequence conflicti969A → T in BAE34024 (PubMed:16141072).Curated1
Sequence conflicti974 – 975HV → QL in AAF21969 (PubMed:10469352).Curated2
Sequence conflicti1020 – 1021KL → NW in AAF21969 (PubMed:10469352).Curated2
Sequence conflicti1049V → C in AAF21969 (PubMed:10469352).Curated1
Sequence conflicti1256V → L in AAF21969 (PubMed:10469352).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AF113751 mRNA Translation: AAF21969.1
BC052468 mRNA Translation: AAH52468.1
AK173056 mRNA Translation: BAD32334.1
AK157272 mRNA Translation: BAE34024.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS39565.1

NCBI Reference Sequences

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RefSeqi
NP_061285.2, NM_018815.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMUST00000032179; ENSMUSP00000032179; ENSMUSG00000030091

Database of genes from NCBI RefSeq genomes

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GeneIDi
54563

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:54563

UCSC genome browser

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UCSCi
uc009cxu.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF113751 mRNA Translation: AAF21969.1
BC052468 mRNA Translation: AAH52468.1
AK173056 mRNA Translation: BAD32334.1
AK157272 mRNA Translation: BAE34024.1
CCDSiCCDS39565.1
RefSeqiNP_061285.2, NM_018815.2

3D structure databases

SMRiQ9QY81
ModBaseiSearch...

Protein-protein interaction databases

BioGridi207678, 2 interactors
IntActiQ9QY81, 2 interactors
MINTiQ9QY81
STRINGi10090.ENSMUSP00000032179

PTM databases

GlyConnecti2567
iPTMnetiQ9QY81
PhosphoSitePlusiQ9QY81
SwissPalmiQ9QY81

Proteomic databases

EPDiQ9QY81
MaxQBiQ9QY81
PaxDbiQ9QY81
PeptideAtlasiQ9QY81
PRIDEiQ9QY81

Genome annotation databases

EnsembliENSMUST00000032179; ENSMUSP00000032179; ENSMUSG00000030091
GeneIDi54563
KEGGimmu:54563
UCSCiuc009cxu.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
23225
MGIiMGI:1859555 Nup210

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
Search...

Phylogenomic databases

eggNOGiKOG1833 Eukaryota
ENOG410XNNU LUCA
GeneTreeiENSGT00390000009491
HOGENOMiHOG000115312
InParanoidiQ9QY81
KOiK14314
OMAiDIICFDS
OrthoDBi843414at2759
PhylomeDBiQ9QY81
TreeFamiTF313331

Enzyme and pathway databases

ReactomeiR-MMU-159227 Transport of the SLBP independent Mature mRNA
R-MMU-159230 Transport of the SLBP Dependant Mature mRNA
R-MMU-159231 Transport of Mature mRNA Derived from an Intronless Transcript
R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-191859 snRNP Assembly
R-MMU-3108214 SUMOylation of DNA damage response and repair proteins
R-MMU-3301854 Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453 Regulation of HSF1-mediated heat shock response
R-MMU-4615885 SUMOylation of DNA replication proteins

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Nup210 mouse

Protein Ontology

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PROi
PR:Q9QY81

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000030091 Expressed in 261 organ(s), highest expression level in bone marrow
ExpressionAtlasiQ9QY81 baseline and differential
GenevisibleiQ9QY81 MM

Family and domain databases

InterProiView protein in InterPro
IPR003343 Big_2
IPR008964 Invasin/intimin_cell_adhesion
PfamiView protein in Pfam
PF02368 Big_2, 1 hit
SMARTiView protein in SMART
SM00635 BID_2, 1 hit
SUPFAMiSSF49373 SSF49373, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPO210_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9QY81
Secondary accession number(s): Q3U031, Q69ZW2, Q7TQM1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: May 16, 2006
Last modified: October 16, 2019
This is version 126 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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