Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Bile salt export pump

Gene

Abcb11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi455 – 462ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1113 – 1120ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-159418 Recycling of bile acids and salts
R-MMU-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bile salt export pump
Alternative name(s):
ATP-binding cassette sub-family B member 11
Sister of P-glycoprotein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Abcb11
Synonyms:Bsep, Spgp
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1351619 Abcb11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 62CytoplasmicSequence analysisAdd BLAST62
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei63 – 83HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini84 – 147ExtracellularSequence analysisAdd BLAST64
Transmembranei148 – 168HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini169 – 215CytoplasmicSequence analysisAdd BLAST47
Transmembranei216 – 236HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini237 – 240ExtracellularSequence analysis4
Transmembranei241 – 261HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini262 – 319CytoplasmicSequence analysisAdd BLAST58
Transmembranei320 – 340HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini341 – 353ExtracellularSequence analysisAdd BLAST13
Transmembranei354 – 374HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini375 – 755CytoplasmicSequence analysisAdd BLAST381
Transmembranei756 – 776HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini777 – 794ExtracellularSequence analysisAdd BLAST18
Transmembranei795 – 815HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini816 – 869CytoplasmicSequence analysisAdd BLAST54
Transmembranei870 – 890HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei891 – 911HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini912 – 979CytoplasmicSequence analysisAdd BLAST68
Transmembranei980 – 1000HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini1001 – 1011ExtracellularSequence analysisAdd BLAST11
Transmembranei1012 – 1032HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini1033 – 1321CytoplasmicSequence analysisAdd BLAST289

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL2073695

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000932971 – 1321Bile salt export pumpAdd BLAST1321

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi109N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi116N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi122N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi125N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei586PhosphothreonineBy similarity1
Modified residuei587PhosphoserineBy similarity1
Modified residuei692PhosphoserineCombined sources1
Modified residuei703PhosphoserineBy similarity1
Modified residuei706PhosphoserineBy similarity1
Modified residuei1321PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9QY30

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9QY30

PRoteomics IDEntifications database

More...
PRIDEi
Q9QY30

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9QY30

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9QY30

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9QY30

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000027048 Expressed in 25 organ(s), highest expression level in liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9QY30 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9QY30 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with HAX1.By similarity

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9QY30, 1 interactor

Molecular INTeraction database

More...
MINTi
Q9QY30

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000099770

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9QY30

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9QY30

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini62 – 385ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST324
Domaini420 – 656ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini755 – 1043ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST289
Domaini1078 – 1316ABC transporter 2PROSITE-ProRule annotationAdd BLAST239

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni651 – 674Interaction with HAX1By similarityAdd BLAST24

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0055 Eukaryota
COG1132 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157564

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG080809

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9QY30

KEGG Orthology (KO)

More...
KOi
K05664

Identification of Orthologs from Complete Genome Data

More...
OMAi
FIQRMTT

TreeFam database of animal gene trees

More...
TreeFami
TF105193

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030278 BSEP
IPR027417 P-loop_NTPase
IPR039421 Type_I_exporter

The PANTHER Classification System

More...
PANTHERi
PTHR24221 PTHR24221, 1 hit
PTHR24221:SF165 PTHR24221:SF165, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9QY30-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDSVILRSV KKFGEENHAF ESDGFHNNDK KSRLQDKKKG EGARVGFFEL
60 70 80 90 100
FRFSSSKDNW LMFMGSVCAL LHGMAQPGMI IVFGILTDIF VEYDIERQEL
110 120 130 140 150
SIPEKVCMNN TIVWINSSFN QNMTNGTSCG LVDINSEVIK FSGIYAGVGV
160 170 180 190 200
AVLILGYFQI RLWVITGARQ IRKMRKFYFR RIMRMEIGWF DCTSVGELNS
210 220 230 240 250
RFSDDINKID EAIADQMALF LQRLSTALSG LLLGFYRGWK LTLVILAVSP
260 270 280 290 300
LIGIGAAVIG LSVAKFTELE LKAYAKAGSI ADEVLSSIRT VAAFGGENKE
310 320 330 340 350
VERYEKNLMF AQRWGIWKGM VMGFFTGYMW CLIFFCYALA FWYGSRLVLD
360 370 380 390 400
EGEYTPGTLI QIFLCVIIAA MNIGNASSCL EIFSTGCSAA SSIFQTIDRQ
410 420 430 440 450
PVMDCMSGDG YKLDRIKGEI EFHNVTFHYP SRPEVKILNN LSMVIKPGET
460 470 480 490 500
TAFVGSSGAG KSTALQLIQR FYDPCEGMVT LDGHDIRSLN IRWLRDQIGI
510 520 530 540 550
VEQEPVLFST TIAENIRLGR EEATMEDIVQ AAKDANAYNF IMALPQQFDT
560 570 580 590 600
LVGEGGGQMS GGQKQRVAIA RALIRKPKIL LLDMATSALD NESEAKVQGA
610 620 630 640 650
LNKIQHGHTI ISVAHRLSTV RSADVIIGFE HGTAVERGTH EELLERKGVY
660 670 680 690 700
FMLVTLQSQE DNTHKETGIK GKDTTEGDTP ERTFSRGSYQ DSLRASIRQR
710 720 730 740 750
SKSQLSHLSH EPPLAIGDHK SSYEDRKDND VLVEEVEPAP VRRILKYNIS
760 770 780 790 800
EWPYILVGAL CAAINGAVTP IYSLLFSQIL KTFSLVDKEQ QRSEIYSMCL
810 820 830 840 850
FFVILGCVSL FTQFLQGYNF AKSGELLTKR LRKFGFKAML RQDIGWFDDL
860 870 880 890 900
KNNPGVLTTR LATDASQVQG ATGSQVGMMV NSFTNIFVAV LIAFLFNWKL
910 920 930 940 950
SLVISVFFPF LALSGAVQTK MLTGFASQDK EILEKAGQIT NEALSNIRTV
960 970 980 990 1000
AGIGVEGRFI KAFEVELEKS YKTAIRKANV YGLCYAFSQG ISFLANSAAY
1010 1020 1030 1040 1050
RYGGYLIVYE DLNFSYVFRV VSSIAMSATA VGRTFSYTPS YAKAKISAAR
1060 1070 1080 1090 1100
FFQLLDRKPP IDVYSGAGEK WDNFQGKIDF IDCKFTYPSR PDIQVLNGLS
1110 1120 1130 1140 1150
VSVDPGQTLA FVGSSGCGKS TSIQLLERFY DPDQGTVMID GHDSKKVNVQ
1160 1170 1180 1190 1200
FLRSNIGIVS QEPVLFDCSI MDNIKYGDNT KEISVERAIA AAKQAQLHDF
1210 1220 1230 1240 1250
VMSLPEKYET NVGIQGSQLS RGEKQRIAIA RAIVRDPKIL LLDEATSALD
1260 1270 1280 1290 1300
TESEKTVQLA LDKAREGRTC IVIAHRLSTI QNSDIIAVMS QGVVIEKGTH
1310 1320
KKLMDQKGAY YKLVITGAPI S
Length:1,321
Mass (Da):146,749
Last modified:June 28, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC71F8D3D0A352BA8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3QNY6J3QNY6_MOUSE
Bile salt export pump
Abcb11
1,321Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti104E → G in AAF14372 (PubMed:10607905).Curated1
Sequence conflicti481L → P in AAD56419 (Ref. 3) Curated1
Sequence conflicti633T → V in AAD56419 (Ref. 3) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF133903 mRNA Translation: AAF14372.1
AL929170 Genomic DNA Translation: CAM24720.1
CH466519 Genomic DNA Translation: EDL27032.1
AF186585 mRNA Translation: AAD56419.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS16090.1

NCBI Reference Sequences

More...
RefSeqi
NP_066302.2, NM_021022.3
XP_006499732.1, XM_006499669.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.439855

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000102709; ENSMUSP00000099770; ENSMUSG00000027048
ENSMUST00000102710; ENSMUSP00000099771; ENSMUSG00000027048

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
27413

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:27413

UCSC genome browser

More...
UCSCi
uc008jya.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF133903 mRNA Translation: AAF14372.1
AL929170 Genomic DNA Translation: CAM24720.1
CH466519 Genomic DNA Translation: EDL27032.1
AF186585 mRNA Translation: AAD56419.1
CCDSiCCDS16090.1
RefSeqiNP_066302.2, NM_021022.3
XP_006499732.1, XM_006499669.3
UniGeneiMm.439855

3D structure databases

ProteinModelPortaliQ9QY30
SMRiQ9QY30
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9QY30, 1 interactor
MINTiQ9QY30
STRINGi10090.ENSMUSP00000099770

Chemistry databases

ChEMBLiCHEMBL2073695

PTM databases

iPTMnetiQ9QY30
PhosphoSitePlusiQ9QY30
SwissPalmiQ9QY30

Proteomic databases

MaxQBiQ9QY30
PaxDbiQ9QY30
PRIDEiQ9QY30

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000102709; ENSMUSP00000099770; ENSMUSG00000027048
ENSMUST00000102710; ENSMUSP00000099771; ENSMUSG00000027048
GeneIDi27413
KEGGimmu:27413
UCSCiuc008jya.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8647
MGIiMGI:1351619 Abcb11

Phylogenomic databases

eggNOGiKOG0055 Eukaryota
COG1132 LUCA
GeneTreeiENSGT00940000157564
HOVERGENiHBG080809
InParanoidiQ9QY30
KOiK05664
OMAiFIQRMTT
TreeFamiTF105193

Enzyme and pathway databases

ReactomeiR-MMU-159418 Recycling of bile acids and salts
R-MMU-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Abcb11 mouse

Protein Ontology

More...
PROi
PR:Q9QY30

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000027048 Expressed in 25 organ(s), highest expression level in liver
ExpressionAtlasiQ9QY30 baseline and differential
GenevisibleiQ9QY30 MM

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030278 BSEP
IPR027417 P-loop_NTPase
IPR039421 Type_I_exporter
PANTHERiPTHR24221 PTHR24221, 1 hit
PTHR24221:SF165 PTHR24221:SF165, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiABCBB_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9QY30
Secondary accession number(s): A2AUN4, Q9QZE8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: June 28, 2011
Last modified: December 5, 2018
This is version 152 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again