Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - Q9QXE2 (DPOLL_MOUSE)

Entry version 162 (25 May 2022)
Sequence version 1 (01 May 2000)
Previous versions | rss
Add a publicationFeedback
Protein

DNA polymerase lambda

Gene

Poll

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.

By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mn2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei310Schiff-base intermediate with DNABy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei384dCTPBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi425ManganeseBy similarity1
Metal bindingi427ManganeseBy similarity1
Metal bindingi488ManganeseBy similarity1
Binding sitei511dCTPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi415 – 418dCTP bindingBy similarity4
Nucleotide bindingi424 – 427dCTP bindingBy similarity4

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase
Biological processDNA damage, DNA repair, DNA replication, DNA synthesis
LigandManganese, Metal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-5693571, Nonhomologous End-Joining (NHEJ)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA polymerase lambdaCurated (EC:2.7.7.7By similarity, EC:4.2.99.-By similarity)
Short name:
Pol LambdaCurated
Alternative name(s):
DNA polymerase kappa1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PollImported
Synonyms:Polk1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1889000, Poll

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000025218

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL3124737

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002187851 – 573DNA polymerase lambdaAdd BLAST573

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9QXE2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9QXE2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9QXE2

PeptideAtlas

More...PeptideAtlasi		Q9QXE2

PRoteomics IDEntifications database

More...PRIDEi		Q9QXE2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		277390

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9QXE2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9QXE2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000025218, Expressed in spermatocyte and 225 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9QXE2, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PCNA.

Interacts with PAXX; promoting POLL recruitment to double-strand breaks (DSBs) and stimulation of the end-filling activity of POLL.

Interacts with XRCC4; promoting POLL recruitment to double-strand breaks (DSBs) and stimulation of the end-filling activity of POLL.

Interacts with NHEJ1/XLF; promoting POLL recruitment to double-strand breaks (DSBs) and stimulation of the end-filling activity of POLL.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		208108, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000026239

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		Q9QXE2

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9QXE2, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9QXE2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9QXE2

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 131BRCTPROSITE-ProRule annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni126 – 204DisorderedSequence analysisAdd BLAST79
Regioni214 – 233DisorderedSequence analysisAdd BLAST20
Regioni263 – 277DNA-bindingBy similarityAdd BLAST15
Regioni343 – 346DNA-bindingBy similarity4
Regioni418 – 427Involved in primer bindingBy similarity10
Regioni464 – 503DNA-bindingBy similarityAdd BLAST40

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi141 – 170Polar residuesSequence analysisAdd BLAST30
Compositional biasi180 – 204Polar residuesSequence analysisAdd BLAST25

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA polymerase type-X family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2534, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158515

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_008698_6_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9QXE2

Identification of Orthologs from Complete Genome Data

More...OMAi		KWHGASA

Database of Orthologous Groups

More...OrthoDBi		1328151at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9QXE2

TreeFam database of animal gene trees

More...TreeFami		TF103011

Family and domain databases

Conserved Domains Database

More...CDDi		cd00141, NT_POLXc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.150.110, 1 hit
3.30.210.10, 1 hit
3.30.460.10, 1 hit
3.40.50.10190, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001357, BRCT_dom
IPR036420, BRCT_dom_sf
IPR002054, DNA-dir_DNA_pol_X
IPR019843, DNA_pol-X_BS
IPR010996, DNA_pol_b-like_N
IPR028207, DNA_pol_B_palm_palm
IPR018944, DNA_pol_lambd_fingers_domain
IPR027421, DNA_pol_lamdba_lyase_dom_sf
IPR037160, DNA_Pol_thumb_sf
IPR022312, DNA_pol_X
IPR002008, DNA_pol_X_beta-like
IPR043519, NT_sf
IPR029398, PolB_thumb

The PANTHER Classification System

More...PANTHERi		PTHR11276, PTHR11276, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14792, DNA_pol_B_palm, 1 hit
PF14791, DNA_pol_B_thumb, 1 hit
PF10391, DNA_pol_lambd_f, 1 hit
PF14716, HHH_8, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00869, DNAPOLX
PR00870, DNAPOLXBETA

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00483, POLXc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47802, SSF47802, 1 hit
SSF52113, SSF52113, 1 hit
SSF81301, SSF81301, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50172, BRCT, 1 hit
PS00522, DNA_POLYMERASE_X, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9QXE2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPQGIVKAF PKRKKSHADL SSKALAKIPK REVGEARGWL SSLRAHIMPA 
        60         70         80         90        100
GIGRARAELF EKQIIHHGGQ VCSAQAPGVT HIVVDEDMDY ERALRLLRLP 
       110        120        130        140        150
QLPPGAQLVK STWLSLCLQE GRLTDTEGFS LPMPKRSLDE PQPSKSGQDA 
       160        170        180        190        200
SAPGTQRDLP RTTLSLSPPH TRAVSPPPTA EKPSRTQAQL SSEDETSDGE 
       210        220        230        240        250
GPQVSSADLQ ALITGHYPTP PEEDGGPDPA PEALDKWVCA QPSSQKATNY 
       260        270        280        290        300
NLHITEKLEV LAKAYSVQGD KWRALGYAKA INALKSFHKP VSSYQEACSI 
       310        320        330        340        350
PGIGKRMAEK VMEILESGHL RKLDHISDSV PVLELFSNIW GAGTKTAQMW 
       360        370        380        390        400
YHQGFRNLED LQSLGSLTAQ QAIGLKHYDD FLDRMPREEA AEIEQTVRIS 
       410        420        430        440        450
AQAFNPGLLC VACGSYRRGK MTCGDVDVLI THPDGRSHRG IFSCLLDSLR 
       460        470        480        490        500
QQGFLTDDLV SQEENGQQQK YLGVCRLPGP GKRHRRLDII VVPYCEFACA 
       510        520        530        540        550
LLYFTGSAHF NRSMRALAKT KGMSLSEHAL SAAVVRNSQG VKVGPGQVLP 
       560        570 
TPTEKDVFKH LGLPYREPAE RDW
Length:573
Mass (Da):62,943
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5B2EA4D1597E06A2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ131889 mRNA Translation: CAB65241.1
AF176099 mRNA Translation: AAF27553.1
BC004767 mRNA Translation: AAH04767.1
AK003392 mRNA Translation: BAB22759.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS29861.1

NCBI Reference Sequences

More...RefSeqi		NP_001317435.1, NM_001330506.1
NP_001317436.1, NM_001330507.1
NP_064416.1, NM_020032.3
XP_011245603.1, XM_011247301.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000026239; ENSMUSP00000026239; ENSMUSG00000025218

Database of genes from NCBI RefSeq genomes

More...GeneIDi		56626

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:56626

UCSC genome browser

More...UCSCi		uc008hrc.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ131889 mRNA Translation: CAB65241.1
AF176099 mRNA Translation: AAF27553.1
BC004767 mRNA Translation: AAH04767.1
AK003392 mRNA Translation: BAB22759.1
CCDSiCCDS29861.1
RefSeqiNP_001317435.1, NM_001330506.1
NP_001317436.1, NM_001330507.1
NP_064416.1, NM_020032.3
XP_011245603.1, XM_011247301.2

3D structure databases

AlphaFoldDBiQ9QXE2
SMRiQ9QXE2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi208108, 1 interactor
STRINGi10090.ENSMUSP00000026239

Chemistry databases

BindingDBiQ9QXE2
ChEMBLiCHEMBL3124737

PTM databases

iPTMnetiQ9QXE2
PhosphoSitePlusiQ9QXE2

Proteomic databases

EPDiQ9QXE2
MaxQBiQ9QXE2
PaxDbiQ9QXE2
PeptideAtlasiQ9QXE2
PRIDEiQ9QXE2
ProteomicsDBi277390

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31295, 245 antibodies from 32 providers

The DNASU plasmid repository

More...DNASUi		56626

Genome annotation databases

EnsembliENSMUST00000026239; ENSMUSP00000026239; ENSMUSG00000025218
GeneIDi56626
KEGGimmu:56626
UCSCiuc008hrc.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		27343
MGIiMGI:1889000, Poll
VEuPathDBiHostDB:ENSMUSG00000025218

Phylogenomic databases

eggNOGiKOG2534, Eukaryota
GeneTreeiENSGT00940000158515
HOGENOMiCLU_008698_6_1_1
InParanoidiQ9QXE2
OMAiKWHGASA
OrthoDBi1328151at2759
PhylomeDBiQ9QXE2
TreeFamiTF103011

Enzyme and pathway databases

ReactomeiR-MMU-5693571, Nonhomologous End-Joining (NHEJ)

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		56626, 9 hits in 106 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Polk, mouse

Protein Ontology

More...PROi		PR:Q9QXE2
RNActiQ9QXE2, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000025218, Expressed in spermatocyte and 225 other tissues
GenevisibleiQ9QXE2, MM

Family and domain databases

CDDicd00141, NT_POLXc, 1 hit
Gene3Di1.10.150.110, 1 hit
3.30.210.10, 1 hit
3.30.460.10, 1 hit
3.40.50.10190, 1 hit
InterProiView protein in InterPro
IPR001357, BRCT_dom
IPR036420, BRCT_dom_sf
IPR002054, DNA-dir_DNA_pol_X
IPR019843, DNA_pol-X_BS
IPR010996, DNA_pol_b-like_N
IPR028207, DNA_pol_B_palm_palm
IPR018944, DNA_pol_lambd_fingers_domain
IPR027421, DNA_pol_lamdba_lyase_dom_sf
IPR037160, DNA_Pol_thumb_sf
IPR022312, DNA_pol_X
IPR002008, DNA_pol_X_beta-like
IPR043519, NT_sf
IPR029398, PolB_thumb
PANTHERiPTHR11276, PTHR11276, 1 hit
PfamiView protein in Pfam
PF14792, DNA_pol_B_palm, 1 hit
PF14791, DNA_pol_B_thumb, 1 hit
PF10391, DNA_pol_lambd_f, 1 hit
PF14716, HHH_8, 1 hit
PRINTSiPR00869, DNAPOLX
PR00870, DNAPOLXBETA
SMARTiView protein in SMART
SM00483, POLXc, 1 hit
SUPFAMiSSF47802, SSF47802, 1 hit
SSF52113, SSF52113, 1 hit
SSF81301, SSF81301, 1 hit
PROSITEiView protein in PROSITE
PS50172, BRCT, 1 hit
PS00522, DNA_POLYMERASE_X, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDPOLL_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9QXE2
Secondary accession number(s): Q9CTJ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: May 1, 2000
Last modified: May 25, 2022
This is version 162 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again