Cnga3

Functionⁱ

GO - Molecular functionⁱ

cGMP binding
Source: RGD
Inferred from direct assayⁱ
- 11387380
intracellular cGMP activated cation channel activity
Source: RGD
Inferred from direct assayⁱ
- 11387380
protein C-terminus binding
Source: RGD
Inferred from physical interactionⁱ
- 23329832

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

inorganic cation import across plasma membrane
Source: RGD
Inferred from direct assayⁱ
- 9278419
ion transmembrane transport
Source: RGD
Inferred from direct assayⁱ
- 11387380
response to cAMP
Source: RGD
Inferred from direct assayⁱ
- 11387380
response to corticosteroid
Source: RGD
Inferred from expression patternⁱ
- 15471576
response to magnesium ion
Source: RGD
Inferred from direct assayⁱ
- 11387380

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ion channelSAAS annotation
Biological process	Ion transport, Transport

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Cyclic nucleotide-gated channelImported
Gene namesⁱ	Name:Cnga3Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus

Organism-specific databases

Rat genome database More...RGDⁱ	70948 Cnga3

RGDⁱ

70948 Cnga3

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	227 – 245	HelicalSequence analysisAdd BLAST		19
Transmembraneⁱ	299 – 321	HelicalSequence analysisAdd BLAST		23

Keywords - Cellular componentⁱ

Membrane

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q9QWN7 RN

Genevisibleⁱ

Q9QWN7 RN

Interactionⁱ

GO - Molecular functionⁱ

protein C-terminus binding
Source: RGD
Inferred from physical interactionⁱ
- 23329832

View the complete GO annotation on QuickGO ...

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9QWN7
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	403 – 517	Cyclic nucleotide-bindingInterPro annotationAdd BLAST		115

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	544 – 564	Sequence analysisAdd BLAST		21
Coiled coilⁱ	569 – 589	Sequence analysisAdd BLAST		21

Keywords - Domainⁱ

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG0500 Eukaryota ENOG410YWWI LUCA
HOVERGENⁱ	HBG000281
KEGG Orthology (KO) More...KOⁱ	K04950

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00038 CAP_ED, 1 hit
Gene3Dⁱ	2.60.120.10, 1 hit
InterProⁱ	View protein in InterPro IPR032406 CLZ_dom IPR018490 cNMP-bd-like IPR018488 cNMP-bd_CS IPR000595 cNMP-bd_dom IPR005821 Ion_trans_dom IPR014710 RmlC-like_jellyroll
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF16526 CLZ, 1 hit PF00027 cNMP_binding, 1 hit PF00520 Ion_trans, 1 hit
SMARTⁱ	View protein in SMART SM00100 cNMP, 1 hit
SUPFAMⁱ	SSF51206 SSF51206, 1 hit
PROSITEⁱ	View protein in PROSITE PS00888 CNMP_BINDING_1, 1 hit PS00889 CNMP_BINDING_2, 1 hit PS50042 CNMP_BINDING_3, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9QWN7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MHQMETSTMV QDNRVSRFII SIRAWAARHL HHEDPTPDSF LDRFHGAEPK 
        60         70         80         90        100
EVSSQERNAQ PNPGGQEPPE GGKGRKKDPI VVDPSSNIYY RWLTAIALPV 
       110        120        130        140        150
FYNWCLLVCR ACFDELQSEH LTLWLVLDYS ADALYVVDML VRARTGFLEQ 
       160        170        180        190        200
GLMVRDTKRL WKHYTKTLHF KLDILSLIPT DLAYLKLGMN YPELRFNRLL 
       210        220        230        240        250
RFSRLFEFFD RTETRTNYPN VFRIGNLVLY TLIIIHWNAC IYFAISKFIG 
       260        270        280        290        300
FGTDSWVYPN TSKPEYGRLS RKYIYSLYWS TLTLTTIGET PPPVKDEEYL 
       310        320        330        340        350
FVVIDFLVGV LIFATIVGNV GSMISNMNAS RAEFQAKIDS IKQYMQFRKV 
       360        370        380        390        400
TKDLETRVIR WFDYLWANRK TVDEKEVLKN LPDKLKAEIA INVHLDTLKK 
       410        420        430        440        450
VRIFQDCEAG LLVELVLKLR PAVFSPGDYI CKKGDIGREM YIIKEGKLAV 
       460        470        480        490        500
VADDGVTQFV VLSDGSYFGE ISILNIKGSK SGNRRTANIR SIGYSDLFCL 
       510        520        530        540        550
SKDDLMETLT EYPDAKRALE EKGRQILMKD NLIDDDLVTA RADARNIEEK 
       560        570        580        590        600
VEYLESSLDG LQTRFARLLA EYSASQMKLK QRLSQLESQM TRRGHGFSPD 
       610 
RENSEDASKA D

Length:611

Mass (Da):70,400

Last modified:May 1, 2000 - v1

Checksum:ⁱ9ACECEF9EEF63AC4

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB002801 mRNA Translation: BAA24353.1
NCBI Reference Sequences More...RefSeqⁱ	NP_445947.1, NM_053495.1
UniGeneⁱ	Rn.10886

Genome annotation databases

GeneIDⁱ	85257
KEGGⁱ	rno:85257

Protein	Similar proteins		Species	Score	Length
Q9QWN7	Cyclic nucleotide gated channel alpha 3, isoform CRA_a		RAT		670
cyclic nucleotide-gated cation channel alpha-3 isoform X1		MESAU		669
Cyclic nucleotide-gated cation channel alpha-3		MOUSE		669
UPI00022F3D73		CRIGR		669
UPI00042AA369		PERMB		669
+12

Protein	Similar proteins		Species	Score	Length
Q9QWN7	Cyclic nucleotide gated channel alpha 3, isoform CRA_a		RAT		670
cyclic nucleotide-gated cation channel alpha-3 isoform X1		MESAU		669
UPI000A319E37		MUSCR		669
UPI00042AA369		PERMB		669
UPI00022F3D73		CRIGR		669
+30

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB002801 mRNA Translation: BAA24353.1
NCBI Reference Sequences More...RefSeqⁱ	NP_445947.1, NM_053495.1
UniGeneⁱ	Rn.10886

3D structure databases

ProteinModelPortalⁱ	Q9QWN7
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	85257
KEGGⁱ	rno:85257

Organism-specific databases

CTDⁱ	1261
Rat genome database More...RGDⁱ	70948 Cnga3

Phylogenomic databases

eggNOGⁱ	KOG0500 Eukaryota ENOG410YWWI LUCA
HOVERGENⁱ	HBG000281
KEGG Orthology (KO) More...KOⁱ	K04950

Gene expression databases

Genevisibleⁱ	Q9QWN7 RN

Genevisibleⁱ

Q9QWN7 RN

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00038 CAP_ED, 1 hit
Gene3Dⁱ	2.60.120.10, 1 hit
InterProⁱ	View protein in InterPro IPR032406 CLZ_dom IPR018490 cNMP-bd-like IPR018488 cNMP-bd_CS IPR000595 cNMP-bd_dom IPR005821 Ion_trans_dom IPR014710 RmlC-like_jellyroll
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF16526 CLZ, 1 hit PF00027 cNMP_binding, 1 hit PF00520 Ion_trans, 1 hit
SMARTⁱ	View protein in SMART SM00100 cNMP, 1 hit
SUPFAMⁱ	SSF51206 SSF51206, 1 hit
PROSITEⁱ	View protein in PROSITE PS00888 CNMP_BINDING_1, 1 hit PS00889 CNMP_BINDING_2, 1 hit PS50042 CNMP_BINDING_3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q9QWN7_RAT
Accessionⁱ	Q9QWN7Primary (citable) accession number: Q9QWN7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 1, 2000
	Last sequence update:	May 1, 2000
	Last modified:	July 18, 2018
	This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

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UniProtKB - Q9QWN7 (Q9QWN7_RAT)

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Cyclic nucleotide-gated channel

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma Membrane

Other locations

Topology

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ