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Entry version 159 (02 Jun 2021)
Sequence version 3 (27 Jul 2011)
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Protein

Baculoviral IAP repeat-containing protein 1a

Gene

Naip1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor-neuron apoptosis induced by a variety of signals (By similarity).

By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi315ZincPROSITE-ProRule annotation1
Metal bindingi318ZincPROSITE-ProRule annotation1
Metal bindingi335ZincPROSITE-ProRule annotation1
Metal bindingi342ZincPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei476ATPBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionProtease inhibitor, Thiol protease inhibitor
Biological processApoptosis
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Protein family/group databases

MEROPS protease database

More...
MEROPSi
I32.001

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Baculoviral IAP repeat-containing protein 1a
Alternative name(s):
Neuronal apoptosis inhibitory protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Naip1
Synonyms:Birc1a, Naip
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1298223, Naip1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001223421 – 1403Baculoviral IAP repeat-containing protein 1aAdd BLAST1403

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9QWK5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9QWK5

PeptideAtlas

More...
PeptideAtlasi
Q9QWK5

PRoteomics IDEntifications database

More...
PRIDEi
Q9QWK5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
273783

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9QWK5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9QWK5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000021640, Expressed in colon and 90 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9QWK5, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via NACHT domain) with APAF1 (via CARD and NACHT domains).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
201684, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000022142

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9QWK5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati63 – 128BIR 1Add BLAST66
Repeati162 – 228BIR 2Add BLAST67
Repeati281 – 346BIR 3Add BLAST66
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini464 – 758NACHTPROSITE-ProRule annotationAdd BLAST295

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Both the BIR and NACHT domains are essential for effective inhibition of pro-CASP9 cleavage. BIR3 domain binds to procaspase-9 and the NACHT domain interacts with the NACHT domain of APAF1 forming a bridge between pro-CASP9 and APAF1 (By similarity).By similarity

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1101, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163369

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005648_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9QWK5

Database of Orthologous Groups

More...
OrthoDBi
268914at2759

TreeFam database of animal gene trees

More...
TreeFami
TF105356

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00022, BIR, 3 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001370, BIR_rpt
IPR032675, LRR_dom_sf
IPR007111, NACHT_NTPase
IPR028789, Naip
IPR040535, NLRC4_HD
IPR041075, NOD2_WH
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR46914, PTHR46914, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00653, BIR, 3 hits
PF05729, NACHT, 1 hit
PF17889, NLRC4_HD, 1 hit
PF17779, NOD2_WH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00238, BIR, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01282, BIR_REPEAT_1, 1 hit
PS50143, BIR_REPEAT_2, 3 hits
PS50837, NACHT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9QWK5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEHGESSED RISEIDYEFL PELSALLGVD AVQLAKSQEE EEHKERMKMK
60 70 80 90 100
KGFNSQMRSE AKRLKTFETY DTFRSWTPQE MAAAGFYHTG VKLGVQCFCC
110 120 130 140 150
SLILFGNSLR KLPIERHKKL RPECEFLQGK DVGNIGKYDI RVKSPEKMLR
160 170 180 190 200
GGKARYHEEE ARLESFEDWP FYAHGTSPRV LSAAGFVFTG KRDTVQCFSC
210 220 230 240 250
GGSLGNWEEG DDPWKEHAKW FPKCEFLQSK KSSEEIAQYI QGYEGFVHVT
260 270 280 290 300
GEHFVNSWVR RELPMVSAYC NDSVFANEEL RMDTFKDWPH ESPVAVDALV
310 320 330 340 350
RAGLFYTGKK GIVQCFSCGG CMEKCTEGDD PIQEHNKFFP NCVFLQTPKS
360 370 380 390 400
SAEVIPALQS HCALPEAMET TSESNHDDPA AVHSTVVGLG RSEAQWFQEA
410 420 430 440 450
RSLSEQLRDN YTKATFRHMN LPEVCSSLGT DHLIGCDVSI ISKHISQPVQ
460 470 480 490 500
GALTIPEVFS NLSSVMCVEG ETGSGKTTFL KRIAFLWASG CCPLLYRFQL
510 520 530 540 550
VFYLSLSSIT PDQGLANIIC AQLLGAGGCI SEVCLSSIIQ QLQHQVLFLL
560 570 580 590 600
DDYSGLASLP QALHTLITKN YLSRTCLLIA VHTNRVRGIR SYLDTSLEIK
610 620 630 640 650
EFPLSNTVYI LKKFFSHNIK RLLEFMVYFG QNEDLQGIHK TPLFVAAVCT
660 670 680 690 700
DWFENPSDQP FQDMALFKSY MQYLSLKHKG AAKPLQATVS SCGQLALTGL
710 720 730 740 750
FSSCFEFNSD DLAEAGVDED EELTTCLMSK FTAQRLRPVY RFLGPLFQEF
760 770 780 790 800
LAAMRLTELL SSDRQEDQDL GLYYLRQINS PLKALTTYNN FLKYVFSHPS
810 820 830 840 850
SKAGPTVVSH LLHLVDETEL LENTYKNEDY VNHPPGTSRI MKGLKELWLL
860 870 880 890 900
SPEYYSSFVS EHLLRIALNF AYESNTVAEC SPFILQFLRG RTLALKVLNL
910 920 930 940 950
QYFRDHPESL LLVKSLEVSI NGNKVPKVVD YSVMEKSFET LQPPTIDQDY
960 970 980 990 1000
ASAFEQMKEH EKNLSENEET IKSIKNIFPL QPPKISSGYW KLSPKPCKIP
1010 1020 1030 1040 1050
RLEVGVTNMG PADQALLQVL MEVFSASQSI EFRLSDSSGF LESIRPALEL
1060 1070 1080 1090 1100
SKASVTKCSM SRLELSRAEQ ELLLTLPALQ SLEVSETNQL PDQLFHNLHK
1110 1120 1130 1140 1150
FLGLKELCVR LDGKPDVLSV LPGEFPNLLH MEKLSIRTSM ESDLSKLVKL
1160 1170 1180 1190 1200
IQNSPNLHVF HLKCDFLSNC DSLMAVLASC KKLREIEFSG RCFEAMPFVN
1210 1220 1230 1240 1250
ILPNFISLKI LNLISQQFPD KETSEKFAQA LGSLRNLEEL LVPTGDGIHQ
1260 1270 1280 1290 1300
VAKLIVRQCL QLPCLRVLAF HYILDNDSVI EIARVATSGG FQKLEKLDLS
1310 1320 1330 1340 1350
MNHKITEEGY RNFFQALDNL PNLQNLNICR HIPECIQVQA TTVKALGQCV
1360 1370 1380 1390 1400
SRLPSLTRLH MLSWLLDEED MKVINDVKER HPQSKRLIIF WKWIVPFSPV

VLE
Length:1,403
Mass (Da):158,724
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i933E23BB1F1DA3E9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VLC9A0A1Y7VLC9_MOUSE
Baculoviral IAP repeat-containing p...
Naip1
388Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y7VJ19A0A1Y7VJ19_MOUSE
Baculoviral IAP repeat-containing p...
Naip1
401Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti343V → I in AAB69223 (PubMed:9693038).Curated1
Sequence conflicti343V → I in AAF82752 (PubMed:10958627).Curated1
Sequence conflicti359Q → L in AAB69223 (PubMed:9693038).Curated1
Sequence conflicti359Q → L in AAF82752 (PubMed:10958627).Curated1
Sequence conflicti624E → K in AAD56763 (PubMed:10501978).Curated1
Sequence conflicti1092D → E in AAF82752 (PubMed:10958627).Curated1
Sequence conflicti1116D → N in AAF82752 (PubMed:10958627).Curated1
Sequence conflicti1123G → R in AAF82752 (PubMed:10958627).Curated1
Sequence conflicti1129L → H in AAB69223 (PubMed:9693038).Curated1
Sequence conflicti1140M → T in AAB69223 (PubMed:9693038).Curated1
Sequence conflicti1140M → T in AAF82752 (PubMed:10958627).Curated1
Sequence conflicti1269A → V in AAF82752 (PubMed:10958627).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF007769 mRNA Translation: AAB69223.1
AF135491 mRNA Translation: AAD56763.1
AF242432 Genomic DNA Translation: AAF82752.1
BC132413 mRNA Translation: AAI32414.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS26729.1

NCBI Reference Sequences

More...
RefSeqi
NP_032696.2, NM_008670.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000022142; ENSMUSP00000022142; ENSMUSG00000021640
ENSMUST00000222155; ENSMUSP00000152583; ENSMUSG00000021640

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
17940

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:17940

UCSC genome browser

More...
UCSCi
uc007rqr.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF007769 mRNA Translation: AAB69223.1
AF135491 mRNA Translation: AAD56763.1
AF242432 Genomic DNA Translation: AAF82752.1
BC132413 mRNA Translation: AAI32414.1
CCDSiCCDS26729.1
RefSeqiNP_032696.2, NM_008670.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi201684, 1 interactor
STRINGi10090.ENSMUSP00000022142

Protein family/group databases

MEROPSiI32.001

PTM databases

iPTMnetiQ9QWK5
PhosphoSitePlusiQ9QWK5

Proteomic databases

MaxQBiQ9QWK5
PaxDbiQ9QWK5
PeptideAtlasiQ9QWK5
PRIDEiQ9QWK5
ProteomicsDBi273783

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
17940

Genome annotation databases

EnsembliENSMUST00000022142; ENSMUSP00000022142; ENSMUSG00000021640
ENSMUST00000222155; ENSMUSP00000152583; ENSMUSG00000021640
GeneIDi17940
KEGGimmu:17940
UCSCiuc007rqr.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
17940
MGIiMGI:1298223, Naip1

Phylogenomic databases

eggNOGiKOG1101, Eukaryota
GeneTreeiENSGT00940000163369
HOGENOMiCLU_005648_0_0_1
InParanoidiQ9QWK5
OrthoDBi268914at2759
TreeFamiTF105356

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
17940, 0 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Naip1, mouse

Protein Ontology

More...
PROi
PR:Q9QWK5
RNActiQ9QWK5, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000021640, Expressed in colon and 90 other tissues
GenevisibleiQ9QWK5, MM

Family and domain databases

CDDicd00022, BIR, 3 hits
Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR001370, BIR_rpt
IPR032675, LRR_dom_sf
IPR007111, NACHT_NTPase
IPR028789, Naip
IPR040535, NLRC4_HD
IPR041075, NOD2_WH
IPR027417, P-loop_NTPase
PANTHERiPTHR46914, PTHR46914, 1 hit
PfamiView protein in Pfam
PF00653, BIR, 3 hits
PF05729, NACHT, 1 hit
PF17889, NLRC4_HD, 1 hit
PF17779, NOD2_WH, 1 hit
SMARTiView protein in SMART
SM00238, BIR, 3 hits
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS01282, BIR_REPEAT_1, 1 hit
PS50143, BIR_REPEAT_2, 3 hits
PS50837, NACHT, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBIR1A_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9QWK5
Secondary accession number(s): A2RT89, Q9JIB5, Q9R017
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: July 27, 2011
Last modified: June 2, 2021
This is version 159 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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