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UniProtKB - Q9PUU5 (Q9PUU5_DANRE)
Protein
Kinesin-like protein
Gene
kif23
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- ATP hydrolysis activity Source: GO_Central
- microtubule binding Source: GO_Central
- microtubule motor activity Source: GO_Central
GO - Biological processi
- cleavage furrow formation Source: ZFIN
- embryonic cleavage Source: ZFIN
- microtubule-based movement Source: GO_Central
- mitotic cytokinesis Source: ZFIN
- mitotic spindle midzone assembly Source: GO_Central
- system development Source: UniProt
- vesicle transport along microtubule Source: ZFIN
Keywordsi
Molecular function | Motor proteinUniRule annotation |
Ligand | ATP-bindingUniRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Kinesin-like proteinUniRule annotation |
Gene namesi | |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-991019-4, kif23 |
Subcellular locationi
Cytoskeleton
- kinesin complex Source: GO_Central
- microtubule Source: ZFIN
Nucleus
- nucleus Source: ZFIN
Plasma Membrane
- cleavage furrow Source: ZFIN
Other locations
- cytoplasm Source: ZFIN
Keywords - Cellular componenti
MicrotubuleUniRule annotationExpressioni
Gene expression databases
Bgeei | ENSDARG00000014943, Expressed in blastula and 35 other tissues |
Interactioni
GO - Molecular functioni
- microtubule binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000026695 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 25 – 436 | Kinesin motorInterPro annotationAdd BLAST | 412 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 26 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 173 – 192 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 674 – 733 | DisorderedSequence analysisAdd BLAST | 60 | |
Regioni | 799 – 867 | DisorderedSequence analysisAdd BLAST | 69 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 553 – 629 | Sequence analysisAdd BLAST | 77 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 682 – 697 | Basic and acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 717 – 732 | Basic and acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 810 – 824 | Basic and acidic residuesSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG0247, Eukaryota |
GeneTreei | ENSGT00940000155837 |
HOGENOMi | CLU_001485_13_0_1 |
OMAi | SIEINAC |
OrthoDBi | 314538at2759 |
TreeFami | TF105232 |
Family and domain databases
Gene3Di | 2.60.40.4330, 1 hit 3.40.850.10, 1 hit |
InterProi | View protein in InterPro IPR032384, Kif23_Arf-bd IPR038105, Kif23_Arf-bd_sf IPR027640, Kinesin-like_fam IPR019821, Kinesin_motor_CS IPR001752, Kinesin_motor_dom IPR036961, Kinesin_motor_dom_sf IPR027417, P-loop_NTPase |
PANTHERi | PTHR24115, PTHR24115, 1 hit |
Pfami | View protein in Pfam PF00225, Kinesin, 1 hit PF16540, MKLP1_Arf_bdg, 1 hit |
PRINTSi | PR00380, KINESINHEAVY |
SMARTi | View protein in SMART SM00129, KISc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00411, KINESIN_MOTOR_1, 1 hit PS50067, KINESIN_MOTOR_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q9PUU5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIRQAKGKTP RRPPPKKPSN NQKDPVGVYC RVRPLGAEDE ECCIEVISNT
60 70 80 90 100
TIQLHAPDGL KANRNGEFKE TQYSFKKVFG IKTTQRELFE DVAKPLAQDL
110 120 130 140 150
IHGKNGLLFT YGVTGSGKTH TMTGSPGQGG LLPRSLDMIF NSIGPYQAKR
160 170 180 190 200
YVFKPDDKNG MEVQNQVDAL LDRQKRDSQT SVPKTPNTRR VDPEFADMIS
210 220 230 240 250
PEEACKAEGV DEDSSYSVFV SYIEIYNNYI YDLLEETPFD PIKPKPPQSK
260 270 280 290 300
ILREDQNHNM YVAGCTEVEV KSTEEAFEVF WRGQKKRRIA NTQLNRESSR
310 320 330 340 350
SHSVFIVKLA QAPLDADGDN VLQDKNQVNV SQLCLVDLAG SERTSRTRAE
360 370 380 390 400
GNRLREAGNI NQSLMTLRTC IEVLRENQMC GTNKMVPYRD SKVTHLFKNY
410 420 430 440 450
FDGEGKVRMV VCVNPKADDY EETLLVMRFA EMTQEVEVAR PVDRPICGFA
460 470 480 490 500
AGRRQRNQAF KEELTRRLEE RGGPVDGDCP TVLNQLLQAF PPLPPCEISG
510 520 530 540 550
PNDDVTLPRL IEALEKRHKI RQMMIEEYNK TATMLKSVLQ EQDGNILSKE
560 570 580 590 600
NVIQEQRGKL GEKDKMLQNQ KNEIDRLEKK SKMLEYKIDI LQKTTNIYEE
610 620 630 640 650
DKRSLQNELE SREQRLQREM SEKRRIEARM QGMVSDTKLK WEKECERRVN
660 670 680 690 700
AKQLEMQNKL WVKDEKLKQL KAIVTEGKTE NRQPQRPSRE KDKVPPKRSA
710 720 730 740 750
SPSPAPTGPP VRPLHRRSHS AGGERWVDHK PTTNVDLDTV MQPNIPNAIK
760 770 780 790 800
VNAPNEKALS KCDKYVLTHQ EVASDGEIQT KLIKGEVFKT RGGGQSVQFT
810 820 830 840 850
DIETLKQETP VAASRKRRSS ESGPDSEPME GNWTDVETRC SVAVEMRAGS
860
NLGPGYQHHG YTKRRKP
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A286Y967 | A0A286Y967_DANRE | Kinesin-like protein | kif23 | 882 | Annotation score: | ||
Q1LUF4 | Q1LUF4_DANRE | Kinesin family member 23 | kif23 | 151 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX942814 Genomic DNA No translation available. AF139990 mRNA Translation: AAF00594.1 |
RefSeqi | NP_571430.1, NM_131355.1 |
Genome annotation databases
Ensembli | ENSDART00000012241.10; ENSDARP00000026695.8; ENSDARG00000014943.13 ENSDART00000159515.2; ENSDARP00000134353.2; ENSDARG00000116561.1 |
GeneIDi | 30627 |
KEGGi | dre:30627 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX942814 Genomic DNA No translation available. AF139990 mRNA Translation: AAF00594.1 |
RefSeqi | NP_571430.1, NM_131355.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000026695 |
Genome annotation databases
Ensembli | ENSDART00000012241.10; ENSDARP00000026695.8; ENSDARG00000014943.13 ENSDART00000159515.2; ENSDARP00000134353.2; ENSDARG00000116561.1 |
GeneIDi | 30627 |
KEGGi | dre:30627 |
Organism-specific databases
CTDi | 9493 |
ZFINi | ZDB-GENE-991019-4, kif23 |
Phylogenomic databases
eggNOGi | KOG0247, Eukaryota |
GeneTreei | ENSGT00940000155837 |
HOGENOMi | CLU_001485_13_0_1 |
OMAi | SIEINAC |
OrthoDBi | 314538at2759 |
TreeFami | TF105232 |
Gene expression databases
Bgeei | ENSDARG00000014943, Expressed in blastula and 35 other tissues |
Family and domain databases
Gene3Di | 2.60.40.4330, 1 hit 3.40.850.10, 1 hit |
InterProi | View protein in InterPro IPR032384, Kif23_Arf-bd IPR038105, Kif23_Arf-bd_sf IPR027640, Kinesin-like_fam IPR019821, Kinesin_motor_CS IPR001752, Kinesin_motor_dom IPR036961, Kinesin_motor_dom_sf IPR027417, P-loop_NTPase |
PANTHERi | PTHR24115, PTHR24115, 1 hit |
Pfami | View protein in Pfam PF00225, Kinesin, 1 hit PF16540, MKLP1_Arf_bdg, 1 hit |
PRINTSi | PR00380, KINESINHEAVY |
SMARTi | View protein in SMART SM00129, KISc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00411, KINESIN_MOTOR_1, 1 hit PS50067, KINESIN_MOTOR_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9PUU5_DANRE | |
Accessioni | Q9PUU5Primary (citable) accession number: Q9PUU5 Secondary accession number(s): A0A0R4IKS5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | May 25, 2022 | |
This is version 154 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |